CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma
Nijhof, Inger S., Casneuf, Tineke, van Velzen, Jeroen, van Kessel, Berris, Axel, Amy E., Syed, Khaja, Groen, Richard W.J., van Duin, Mark, Sonneveld, Pieter, Minnema, Monique C., Zweegman, Sonja, Chiu, Christopher, Bloem, Andries C., Mutis, Tuna, Lokhorst, Henk M., Sasser, A.Kate, van de Donk, Niels W.C.J.
Published in Blood (18.08.2016)
Published in Blood (18.08.2016)
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Effect of daratumumab on normal plasma cells, polyclonal immunoglobulin levels, and vaccination responses in extensively pre-treated multiple myeloma patients
Frerichs, Kristine A, Bosman, Patricia W C, van Velzen, Jeroen F, Fraaij, Pieter L A, Koopmans, Marion P G, Rimmelzwaan, Guus F, Nijhof, Inger S, Bloem, Andries C, Mutis, Tuna, Zweegman, Sonja, van de Donk, Niels W C J
Published in Haematologica (Roma) (01.06.2020)
Published in Haematologica (Roma) (01.06.2020)
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Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients
Franssen, Laurens E, Nijhof, Inger S, Couto, Suzana, Levin, Mark-David, Bos, Gerard M J, Broijl, Annemiek, Klein, Saskia K, Ren, Yan, Wang, Maria, Koene, Harry R, Bloem, Andries C, Beeker, Aart, Faber, Laura M, van der Spek, Ellen, Raymakers, Reinier, Leguit, Roos J, Sonneveld, Pieter, Zweegman, Sonja, Lokhorst, Henk, Mutis, Tuna, Thakurta, Anjan, Qian, Xiaozhong, van de Donk, Niels W C J
Published in Haematologica (Roma) (01.08.2018)
Published in Haematologica (Roma) (01.08.2018)
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CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia
van Montfrans, Joris M., MD, PhD, Hoepelman, Andy I.M., MD, PhD, Otto, Sigrid, BSc, van Gijn, Marielle, PhD, van de Corput, Lisette, PhD, de Weger, Roel A., PhD, Monaco-Shawver, Linda, BSc, Banerjee, Pinaki P., PhD, Sanders, Elisabeth A.M., MD, PhD, Jol–van der Zijde, Cornelia M., PhD, Betts, Michael R., PhD, Orange, Jordan S., MD, PhD, Bloem, Andries C., PhD, Tesselaar, Kiki, PhD
Published in Journal of allergy and clinical immunology (01.03.2012)
Published in Journal of allergy and clinical immunology (01.03.2012)
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Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma
Groen, Richard W.J., Noort, Willy A., Raymakers, Reinier A., Prins, Henk-Jan, Aalders, Linda, Hofhuis, Frans M., Moerer, Petra, van Velzen, Jeroen F., Bloem, Andries C., van Kessel, Berris, Rozemuller, Henk, van Binsbergen, Ellen, Buijs, Arjan, Yuan, Huipin, de Bruijn, Joost D., de Weers, Michel, Parren, Paul W.H.I., Schuringa, Jan Jacob, Lokhorst, Henk M., Mutis, Tuna, Martens, Anton C.M.
Published in Blood (19.07.2012)
Published in Blood (19.07.2012)
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Novel data analysis method for multicolour flow cytometry links variability of multiple markers on single cells to a clinical phenotype
Tinnevelt, Gerjen H., Kokla, Marietta, Hilvering, Bart, van Staveren, Selma, Folcarelli, Rita, Xue, Luzheng, Bloem, Andries C., Koenderman, Leo, Buydens, Lutgarde M. C., Jansen, Jeroen J.
Published in Scientific reports (14.07.2017)
Published in Scientific reports (14.07.2017)
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Lethal neonatal bone marrow failure syndrome with multiple congenital abnormalities, including limb defects, due to a constitutional deletion of 3' MECOM
van der Veken, Lars T, Maiburg, Merel C, Groenendaal, Floris, van Gijn, Mariëlle E, Bloem, Andries C, Erpelinck, Claudia, Gröschel, Stefan, Sanders, Mathijs A, Delwel, Ruud, Bierings, Marc B, Buijs, Arjan
Published in Haematologica (Roma) (01.04.2018)
Published in Haematologica (Roma) (01.04.2018)
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Illegitimate WNT Signaling Promotes Proliferation of Multiple Myeloma Cells
Patrick W. B. Derksen, Tjin, Esther, Meijer, Helen P., Klok, Melanie D., Harold D. Mac Gillavry, Marinus H. J. van Oers, Lokhorst, Henk M., Bloem, Andries C., Clevers, Hans, Nusse, Roel, van der Neut, Ronald, Spaargaren, Marcel, Pals, Steven T., Weissman, Irving L.
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2004)
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Lymphoblastic lymphoma with a triple hit profile: a rare but distinct and relevant entity
Hiemcke-Jiwa, Laura S., MD, Leguit, Roos J., MD, van der Veken, Lars T., PhD, Buijs, Arjan, PhD, Leeuwis, Jan Willem, MD, PhD, de Boer, Mirthe, MD, Jiwa, N. Mehdi, MD, PhD, Bloem, Andries C., PhD, Petersen, Eefke J., MD, PhD, de Weger, Roel A., PhD, Huibers, Manon M.H., PhD
Published in Human pathology (01.05.2017)
Published in Human pathology (01.05.2017)
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Defective calcium signaling and disrupted CD20–B-cell receptor dissociation in patients with common variable immunodeficiency disorders
van de Ven, Annick A.J.M., MD, Compeer, Ewoud B., MSc, Bloem, Andries C., PhD, van de Corput, Lisette, PhD, van Gijn, Marielle, PhD, van Montfrans, Joris M., MD, PhD, Boes, Marianne, PhD
Published in Journal of allergy and clinical immunology (01.03.2012)
Published in Journal of allergy and clinical immunology (01.03.2012)
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Salivary immune responses to the 7-valent pneumococcal conjugate vaccine in the first 2 years of life
Rodenburg, Gerwin D, Sanders, Elisabeth A M, van Gils, Elske J M, Veenhoven, Reinier H, Zborowski, Tomasz, van den Dobbelsteen, Germie P J M, Bloem, Andries C, Berbers, Guy A M, Bogaert, Debby
Published in PloS one (16.10.2012)
Published in PloS one (16.10.2012)
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Rapid Identification of Clinical Relevant Minor Histocompatibility Antigens via Genome-Wide Zygosity-Genotype Correlation Analysis
SPAAPEN, Robbert M, DE KORT, Ron A. L, VAN DEN OUDENALDER, Kelly, VAN ELK, Maureen, BLOEM, Andries C, LOKHORST, Henk M, MUTIS, Tuna
Published in Clinical cancer research (01.12.2009)
Published in Clinical cancer research (01.12.2009)
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Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab
Krejcik, Jakub, Frerichs, Kris A, Nijhof, Inger S, van Kessel, Berris, van Velzen, Jeroen F, Bloem, Andries C, Broekmans, Marloes E C, Zweegman, Sonja, van Meerloo, Johan, Musters, René J P, Poddighe, Pino J, Groen, Richard W J, Chiu, Christopher, Plesner, Torben, Lokhorst, Henk M, Sasser, A Kate, Mutis, Tuna, van de Donk, Niels W C J
Published in Clinical cancer research (15.12.2017)
Published in Clinical cancer research (15.12.2017)
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Gene-expression profiling of CD34+ cells from various hematopoietic stem-cell sources reveals functional differences in stem-cell activity
Ng, Yuk Yin, Kessel, Berris, Lokhorst, Henk M., Baert, Miranda R. M., Burg, Caroline M. M., Bloem, Andries C., Staal, Frank J. T.
Published in Journal of leukocyte biology (01.02.2004)
Published in Journal of leukocyte biology (01.02.2004)
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A bioluminescence imaging based in vivo model for preclinical testing of novel cellular immunotherapy strategies to improve the graft-versus-myeloma effect
Rozemuller, Henk, van der Spek, Ellen, Bogers-Boer, Lijnie H, Zwart, Mieke C, Verweij, Vivienne, Emmelot, Maarten, Groen, Richard W, Spaapen, Robbert, Bloem, Andries C, Lokhorst, Henk M, Mutis, Tuna, Martens, Anton C
Published in Haematologica (Roma) (01.07.2008)
Published in Haematologica (Roma) (01.07.2008)
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Protein Geranylgeranylation Is Critical for the Regulation of Survival and Proliferation of Lymphoma Tumor Cells
VAN DE DONK, Niels W. C. J, SCHOTTE, Diana, KAMPHUIS, Marloes M. J, VAN MARION, Ariënne M. W, VAN KESSEL, Berris, BLOEM, Andries C, LOKHORST, Henk M
Published in Clinical cancer research (15.11.2003)
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Published in Clinical cancer research (15.11.2003)
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Phase 1/2 study of lenalidomide combined with low-dose cyclophosphamide and prednisone in lenalidomide-refractory multiple myeloma
Nijhof, Inger S., Franssen, Laurens E., Levin, Mark-David, Bos, Gerard M.J., Broijl, Annemiek, Klein, Saskia K., Koene, Harry R., Bloem, Andries C., Beeker, Aart, Faber, Laura M., van der Spek, Ellen, Ypma, Paula F., Raymakers, Reinier, van Spronsen, Dick-Johan, Westerweel, Peter E., Oostvogels, Rimke, van Velzen, Jeroen, van Kessel, Berris, Mutis, Tuna, Sonneveld, Pieter, Zweegman, Sonja, Lokhorst, Henk M., van de Donk, Niels W.C.J.
Published in Blood (10.11.2016)
Published in Blood (10.11.2016)
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