The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling
Ochodnicka-Mackovicova, Katarina, Bahjat, Mahnoush, Maas, Chiel, van der Veen, Amélie, Bloedjes, Timon A, de Bruin, Alexander M, van Andel, Harmen, Schrader, Carol E, Hendriks, Rudi W, Verhoeyen, Els, Bende, Richard J, van Noesel, Carel J M, Guikema, Jeroen E J
Published in The Journal of immunology (1950) (01.10.2016)
Published in The Journal of immunology (1950) (01.10.2016)
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AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma
Bloedjes, Timon A., de Wilde, Guus, Maas, Chiel, Eldering, Eric, Bende, Richard J., van Noesel, Carel J.M., Pals, Steven T., Spaargaren, Marcel, Guikema, Jeroen E.J.
Published in Blood advances (08.09.2020)
Published in Blood advances (08.09.2020)
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NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity
Ochodnicka-Mackovicova, Katarina, Bahjat, Mahnoush, Bloedjes, Timon A., Maas, Chiel, de Bruin, Alexander M., Bende, Richard J., van Noesel, Carel J.M., Guikema, Jeroen E.J.
Published in Blood (10.09.2015)
Published in Blood (10.09.2015)
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SMG1, a nonsense‐mediated mRNA decay (NMD) regulator, as a candidate therapeutic target in multiple myeloma
Leeksma, Alexander C., Derks, Ingrid A. M., Garrick, Brett, Jongejan, Aldo, Colombo, Martino, Bloedjes, Timon, Trowe, Torsten, Leisten, Jim C., Howarth, Michelle, Malek, Mehnaz, Mortensen, Deborah S., Blease, Kate, Groza, Mathew C., Narla, Rama Krishna, Loos, Remco, Kersten, Marie‐José, Moerland, Perry D., Guikema, Jeroen E. J., Kater, Arnon P., Eldering, Eric, Filvaroff, Ellen H.
Published in Molecular oncology (01.02.2023)
Published in Molecular oncology (01.02.2023)
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Journal Article
AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity
Bloedjes, Timon A., de Wilde, Guus, Khan, Gerarda H., Ashby, Timothy C., Shaughnessy, John D., Zhan, Fenghuang, Houtkooper, Riekelt H., Bende, Richard J., van Noesel, Carel J. M., Spaargaren, Marcel, Guikema, Jeroen E. J.
Published in Blood advances (09.05.2023)
Published in Blood advances (09.05.2023)
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Journal Article
Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay
Bahjat, Mahnoush, Bloedjes, Timon A, van der Veen, Amélie, de Wilde, Guus, Maas, Chiel, Guikema, Jeroen E J
Published in Journal of visualized experiments (09.06.2017)
Published in Journal of visualized experiments (09.06.2017)
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The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors
Bahjat, Mahnoush, de Wilde, Guus, van Dam, Tijmen, Maas, Chiel, Bloedjes, Timon, Bende, Richard J., van Noesel, Carel J.M., Luijks, Dieuwertje M., Eldering, Eric, Kersten, Marie José, Guikema, Jeroen E.J.
Published in Cell cycle (Georgetown, Tex.) (17.09.2019)
Published in Cell cycle (Georgetown, Tex.) (17.09.2019)
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Journal Article
Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay
Bahjat, Mahnoush, Bloedjes, Timon A., van der Veen, Amélie, de Wilde, Guus, Maas, Chiel, Guikema, Jeroen E. J.
Published in Journal of visualized experiments (09.06.2017)
Published in Journal of visualized experiments (09.06.2017)
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Journal Article
Targeting AKT elicits tumor suppressive functions of FOXO transcription factors and GSK3 kinase in Multiple Myeloma
Bloedjes, Timon A, De Wilde, Guus, Maas, Chiel, Eldering, Eric E, Bende, Richard J, Van Noesel, Carel J, Pals, Steven T, Spaargaren, Marcel, Guikema, Jeroen E
Published in bioRxiv (24.10.2019)
Published in bioRxiv (24.10.2019)
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