RORγt and RORα signature genes in human Th17 cells
Castro, Glenda, Liu, Xuejun, Ngo, Karen, De Leon-Tabaldo, Aimee, Zhao, Shanrong, Luna-Roman, Rosa, Yu, Jingxue, Cao, Tinghua, Kuhn, Robert, Wilkinson, Patrick, Herman, Krystal, Nelen, Marina I, Blevitt, Jonathan, Xue, Xiaohua, Fourie, Anne, Fung-Leung, Wai-Ping
Published in PloS one (01.08.2017)
Published in PloS one (01.08.2017)
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Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation
Soroosh, Pejman, Wu, Jiejun, Xue, Xiaohua, Song, Jiao, Sutton, Steven W., Sablad, Marciano, Yu, Jingxue, Nelen, Marina I., Liu, Xuejun, Castro, Glenda, Luna, Rosa, Crawford, Shelby, Banie, Homayon, Dandridge, Rose A., Deng, Xiaohu, Bittner, Anton, Kuei, Chester, Tootoonchi, Mandana, Rozenkrants, Natasha, Herman, Krystal, Gao, Jingjin, Yang, Xia V., Sachen, Kacey, Ngo, Karen, Fung-Leung, Wai-Ping, Nguyen, Steven, de Leon-Tabaldo, Aimee, Blevitt, Jonathan, Zhang, Yan, Cummings, Maxwell D., Rao, Tadimeti, Mani, Neelakandha S., Liu, Changlu, McKinnon, Murray, Milla, Marcos E., Fourie, Anne M., Sun, Siquan
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.2014)
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Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein–Protein Interaction
Blevitt, Jonathan M, Hack, Michael D, Herman, Krystal L, Jackson, Paul F, Krawczuk, Paul J, Lebsack, Alec D, Liu, Annie X, Mirzadegan, Taraneh, Nelen, Marina I, Patrick, Aaron N, Steinbacher, Stefan, Milla, Marcos E, Lumb, Kevin J
Published in Journal of medicinal chemistry (27.04.2017)
Published in Journal of medicinal chemistry (27.04.2017)
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Coupling to Gq Signaling Is Required for Cardioprotection by an Alpha-1A-Adrenergic Receptor Agonist
Myagmar, Bat-Erdene, Ismaili, Taylor, Swigart, Philip M, Raghunathan, Anaha, Baker, Anthony J, Sahdeo, Sunil, Blevitt, Jonathan M, Milla, Marcos E, Simpson, Paul C
Published in Circulation research (13.09.2019)
Published in Circulation research (13.09.2019)
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A highly efficient, high-throughput lipidomics platform for the quantitative detection of eicosanoids in human whole blood
Song, Jiao, Liu, Xuejun, Wu, Jiejun, Meehan, Michael J., Blevitt, Jonathan M., Dorrestein, Pieter C., Milla, Marcos E.
Published in Analytical biochemistry (15.02.2013)
Published in Analytical biochemistry (15.02.2013)
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Journal Article
Phenotyping drug polypharmacology via eicosanoid profiling of blood[S]
Song, Jiao, Liu, Xuejun, Rao, Tadimeti S., Chang, Leon, Meehan, Michael J., Blevitt, Jonathan M., Wu, Jiejun, Dorrestein, Pieter C., Milla, Marcos E.
Published in Journal of lipid research (01.08.2015)
Published in Journal of lipid research (01.08.2015)
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A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors
Blevitt, Jonathan M., Hack, Michael D., Herman, Krystal, Chang, Leon, Keith, John M., Mirzadegan, Tara, Rao, Navin L., Lebsack, Alec D., Milla, Marcos E.
Published in The Journal of biological chemistry (10.06.2016)
Published in The Journal of biological chemistry (10.06.2016)
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Cloning and Pharmacological Characterization of a Fourth Histamine Receptor (H4) Expressed in Bone Marrow
Liu, C, Ma, X, Jiang, X, Wilson, S J, Hofstra, C L, Blevitt, J, Pyati, J, Li, X, Chai, W, Carruthers, N, Lovenberg, T W
Published in Molecular pharmacology (01.03.2001)
Published in Molecular pharmacology (01.03.2001)
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Journal Article
Polypharmacology of Small-Molecule Modulators of the 5-Lipoxygenase Activating Protein (FLAP) Observed via a High-throughput Lipidomics Platform
Song, Jiao, Liu, Xuejun, Zhu, Jian, Tootoonchi, Mandana, Keith, John M, Meduna, Steven P, Dvorak, Curt A, Eccles, Wendy, Krawczuk, Paul J, Blevitt, Jonathan M, Wu, Jiejun, Rao, Navin L, Lebsack, Alec D, Milla, Marcos E
Published in Journal of biomolecular screening (01.02.2016)
Published in Journal of biomolecular screening (01.02.2016)
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Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase
Eccles, Wendy, Blevitt, Jonathan M., Booker, Jamila N., Chrovian, Christa C., Crawford, Shelby, de Leon, Aimee Rose, Deng, Xiaohu, Fourie, Anne M., Grice, Cheryl A., Herman, Krystal, Karlsson, Lars, Kearney, Aaron M., Lee-Dutra, Alice, Liang, Jimmy, Luna, Rosa, Pippel, Dan, Rao, Navin, Riley, Jason P., Santillan, Alejandro, Savall, Brad, Tanis, Virginia M., Xue, Xiaohua, Young, Arlene L.
Published in Bioorganic & medicinal chemistry letters (01.02.2013)
Published in Bioorganic & medicinal chemistry letters (01.02.2013)
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A novel B-RAF inhibitor blocks interleukin-8 (IL-8) synthesis in human melanoma xenografts, revealing IL-8 as a potential pharmacodynamic biomarker
Crawford, Shelby, Belajic, Daniel, Wei, Jianmei, Riley, Jason P, Dunford, Paul J, Bembenek, Scott, Fourie, Anne, Edwards, James P, Karlsson, Lars, Brunmark, Anders, Wolin, Ronald L, Blevitt, Jonathan M
Published in Molecular cancer therapeutics (01.03.2008)
Published in Molecular cancer therapeutics (01.03.2008)
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Journal Article
Azabenzthiazole inhibitors of leukotriene A4 hydrolase
Tanis, Virginia M., Bacani, Genesis M., Blevitt, Jonathan M., Chrovian, Christa C., Crawford, Shelby, De Leon, Aimee, Fourie, Anne M., Gomez, Laurent, Grice, Cheryl A., Herman, Krystal, Kearney, Aaron M., Landry-Bayle, Adrienne M., Lee-Dutra, Alice, Nelson, Jay, Riley, Jason P., Santillán, Alejandro, Wiener, John J.M., Xue, Xiaohua, Young, Arlene L.
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
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Journal Article
2-Aryl benzimidazoles featuring alkyl-linked pendant alcohols and amines as inhibitors of checkpoint kinase Chk2
Neff, Danielle K., Lee-Dutra, Alice, Blevitt, Jonathan M., Axe, Frank U., Hack, Michael D., Buma, Johnathan C., Rynberg, Raymond, Brunmark, Anders, Karlsson, Lars, Breitenbucher, J. Guy
Published in Bioorganic & medicinal chemistry (01.12.2007)
Published in Bioorganic & medicinal chemistry (01.12.2007)
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Dual binding site inhibitors of B-RAF kinase
Wolin, Ronald L., Bembenek, Scott D., Wei, Jianmei, Crawford, Shelby, Lundeen, Katherine, Brunmark, Anders, Karlsson, Lars, Edwards, James P., Blevitt, Jonathan M.
Published in Bioorganic & medicinal chemistry (01.05.2008)
Published in Bioorganic & medicinal chemistry (01.05.2008)
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A highly selective, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor has potent activity in vitro and in vivo
LaMontagne, Kenneth R., Butler, Jeannene, Borowski, Virna B., Fuentes-Pesquera, Angel R., Blevitt, Jonathan M., Huang, Shenlin, Li, Ronghua, Connolly, Peter J., Greenberger, Lee M.
Published in Angiogenesis (London) (01.09.2009)
Published in Angiogenesis (London) (01.09.2009)
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High-throughput phenotypic screen identifies a new family of potent anti-amoebic compounds
Sauvey, Conall, Meewan, Ittipat, Ehrenkaufer, Gretchen, Blevitt, Jonathan, Jackson, Paul, Abagyan, Ruben
Published in PloS one (09.05.2023)
Published in PloS one (09.05.2023)
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Phosphoinositide 3-kinase gamma (PI3Kgamma) inhibitors for the treatment of inflammation and autoimmune disease
Venable, Jennifer D, Ameriks, Michael K, Blevitt, Jonathan M, Thurmond, Robin L, Fung-Leung, Wai-Ping
Published in Recent patents on inflammation & allergy drug discovery (01.01.2010)
Published in Recent patents on inflammation & allergy drug discovery (01.01.2010)
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Journal Article
Coupling to Gq Signaling Is Required for Cardioprotection by an Alpha-1A-Adrenergic Receptor Agonist
Myagmar, Bat-Erdene, Ismaili, Taylor, Swigart, Philip, Raghunathan, Anaha, Baker, Anthony, Sahdeo, Sunil, Blevitt, Jonathan, Milla, Marcos, Simpson, Paul
Published in Journal of molecular and cellular cardiology (01.11.2018)
Published in Journal of molecular and cellular cardiology (01.11.2018)
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Journal Article
ROR[gamma]t and ROR[alpha] signature genes in human Th17 cells
Castro, Glenda, Liu, Xuejun, Ngo, Karen, De Leon-Tabaldo, Aimee, Zhao, Shanrong, Luna-Roman, Rosa, Yu, Jingxue, Cao, Tinghua, Kuhn, Robert, Wilkinson, Patrick, Herman, Krystal, Nelen, Marina I, Blevitt, Jonathan, Xue, Xiaohua, Fourie, Anne, Fung-Leung, Wai-Ping
Published in PloS one (01.08.2017)
Published in PloS one (01.08.2017)
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Journal Article
소분자 조절제를 사용한 IL-17 표적 결합 검정을 위한 조성물 및 방법
XUE XIAOHUA, STRASNER AMY, DE LEON TABALDO AIMEE ROSE, DEPRIMO SAMUEL E, BLEVITT JONATHAN M, LEUNG WAI PING, GOLDBERG STEVEN
Year of Publication 31.05.2022
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Year of Publication 31.05.2022
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