GENETICALLY MODIFIED, LIVE ATTENUATED DENGUE VIRUS TYPE 3 VACCINE CANDIDATES
BLANEY, JOSEPH E., JR, HANSON, CHRISTOPHER T, FIRESTONE, CAI-YEN, HANLEY, KATHRYN A, MURPHY, BRIAN R, WHITEHEAD, STEPHEN S
Published in The American journal of tropical medicine and hygiene (01.12.2004)
Published in The American journal of tropical medicine and hygiene (01.12.2004)
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Journal Article
Immunization with a Single Major Histocompatibility Complex Class I-Restricted Cytotoxic T-Lymphocyte Recognition Epitope of Herpes Simplex Virus Type 2 Confers Protective Immunity
Blaney, Jr, J E, Nobusawa, E, Brehm, M A, Bonneau, R H, Mylin, L M, Fu, T M, Kawaoka, Y, Tevethia, S S
Published in Journal of Virology (01.12.1998)
Published in Journal of Virology (01.12.1998)
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Journal Article
Chemical Mutagenesis of Dengue Virus Type 4 Yields Mutant Viruses Which Are Temperature Sensitive in Vero Cells or Human Liver Cells and Attenuated in Mice
Blaney, Jr, J E, Johnson, D H, Firestone, C Y, Hanson, C T, Murphy, B R, Whitehead, S S
Published in Journal of Virology (01.10.2001)
Published in Journal of Virology (01.10.2001)
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Journal Article
rDEN4 Delta 30, a Live Attenuated Dengue Virus Type 4 Vaccine Candidate, Is Safe, Immunogenic, and Highly Infectious in Healthy Adult Volunteers
Durbin, A P, Whitehead, S S, McArthur, J, Perreault, J R, Blaney, JE Jr, Thumar, B, Murphy, B R, Karron, R A
Published in The Journal of infectious diseases (01.03.2005)
Published in The Journal of infectious diseases (01.03.2005)
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Journal Article
Phase I Clinical Evaluation of rDEN4 Delta 30-200,201: A Live Attenuated Dengue 4 Vaccine Candidate Designed for Decreased Hepatotoxicity
McArthur, J H, Durbin, A P, Marron, JA, Wanionek, KA, Thumar, B, Pierro, D J, Schmidt, A C, Blaney, JE Jr, Murphy, B R, Whitehead, S S
Published in The American journal of tropical medicine and hygiene (01.11.2008)
Published in The American journal of tropical medicine and hygiene (01.11.2008)
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Journal Article
A Live, Attenuated Dengue Virus Type 1 Vaccine Candidate with a 30-Nucleotide Deletion in the 3′ Untranslated Region Is Highly Attenuated and Immunogenic in Monkeys
Whitehead, Stephen S, Falgout, Barry, Hanley, Kathryn A, Blaney, Jr, Joseph E, Markoff, Lewis, Murphy, Brian R
Published in Journal of Virology (01.01.2003)
Published in Journal of Virology (01.01.2003)
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Journal Article
Development of a Live Attenuated Dengue Virus Vaccine Using Reverse Genetics
Blaney, Joseph E., Durbin, Anna P., Murphy, Brian R., Whitehead, Stephen S.
Published in Viral Immunology (01.03.2006)
Published in Viral Immunology (01.03.2006)
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Journal Article
Substitution of the structural genes of dengue virus type 4 with those of type 2 results in chimeric vaccine candidates which are attenuated for mosquitoes, mice, and rhesus monkeys
Whitehead, Stephen S, Hanley, Kathryn A, Blaney, Joseph E, Gilmore, Lara E, Elkins, William R, Murphy, Brian R
Published in Vaccine (01.10.2003)
Published in Vaccine (01.10.2003)
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Journal Article
Genetic Basis of Attenuation of Dengue Virus Type 4 Small Plaque Mutants with Restricted Replication in Suckling Mice and in SCID Mice Transplanted with Human Liver Cells
Blaney, Joseph E., Johnson, Daniel H., Manipon, Gracielle G., Firestone, Cai-Yen, Hanson, Christopher T., Murphy, Brian R., Whitehead, Stephen S.
Published in Virology (New York, N.Y.) (15.08.2002)
Published in Virology (New York, N.Y.) (15.08.2002)
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Journal Article
Temperature sensitive mutations in the genes encoding the NS1, NS2A, NS3, and NS5 nonstructural proteins of dengue virus type 4 restrict replication in the brains of mice
Blaney, Jr, J E, Manipon, G G, Murphy, B R, Whitehead, S S
Published in Archives of virology (01.05.2003)
Published in Archives of virology (01.05.2003)
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Journal Article
A trade-off in replication in mosquito versus mammalian systems conferred by a point mutation in the NS4B protein of dengue virus type 4
Hanley, Kathryn A, Manlucu, Luella R, Gilmore, Lara E, Blaney, Joseph E, Hanson, Christopher T, Murphy, Brian R, Whitehead, Stephen S
Published in Virology (New York, N.Y.) (20.07.2003)
Published in Virology (New York, N.Y.) (20.07.2003)
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Journal Article
Paired Charge-to-Alanine Mutagenesis of Dengue Virus Type 4 NS5 Generates Mutants with Temperature-Sensitive, Host Range, and Mouse Attenuation Phenotypes
Hanley, Kathryn A, Lee, Jay J, Blaney, Jr, Joseph E, Murphy, Brian R, Whitehead, Stephen S
Published in Journal of Virology (01.01.2002)
Published in Journal of Virology (01.01.2002)
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Journal Article
Mutations which enhance the replication of dengue virus type 4 and an antigenic chimeric dengue virus type 2/4 vaccine candidate in Vero cells
Blaney, Joseph E, Manipon, Gracielle G, Firestone, Cai-Yen, Johnson, Daniel H, Hanson, Christopher T, Murphy, Brian R, Whitehead, Stephen S
Published in Vaccine (01.10.2003)
Published in Vaccine (01.10.2003)
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Journal Article
CONSTRUCTION OF WEST NILE VIRUS AND DENGUE VIRUS CHIMERAS FOR USE IN A LIVE VIRUS VACCINE TO PREVENT DISEASE CAUSED BY WEST NILE VIRUS
WHITEHEAD, STEPHEN, S, PUTNAK, JOSEPH R, CHANOCK, ROBERT M, MURPHY, BRIAN R, PLETNEV, ALEXANDER G, BLANEY, JOSEPH E., JR
Year of Publication 24.11.2015
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Year of Publication 24.11.2015
Patent
DEVELOPMENT OF MUTATIONS USEFUL FOR ATTENUATING DENGUE VIRUSES AND CHIMERIC DENGUE VIRUSES
WHITEHEAD, STEPHEN, S, BLANEY, JOSEPH, E., JR, MURPHY, BRIAN, R, HANLEY, KATHRYN, A
Year of Publication 14.11.2012
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Year of Publication 14.11.2012
Patent