In vivo selection of retrovirally transduced hematopoietic stem cells
Sorrentino, Brian P, Allay, James A, Persons, Derek A, Galipeau, Jacques, Riberdy, Janice M, Ashmun, Richard A, Blakley, Raymond L
Published in Nature medicine (01.10.1998)
Published in Nature medicine (01.10.1998)
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Comparison of Two Independent Crystal Structures of Human Dihydrofolate Reductase Ternary Complexes Reduced with Nicotinamide Adenine Dinucleotide Phosphate and the Very Tight-Binding Inhibitor PT523
Cody, Vivian, Galitsky, Nikolai, Luft, Joseph R, Pangborn, Walter, Rosowsky, Andre, Blakley, Raymond L
Published in Biochemistry (Easton) (11.11.1997)
Published in Biochemistry (Easton) (11.11.1997)
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Pharmacokinetics of cladribine (2-chlorodeoxyadenosine) in children with acute leukemia
KEARNS, C. M, BLAKLEY, R. L, SANTANA, V. M, CROM, W. R
Published in Cancer research (Chicago, Ill.) (01.03.1994)
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Published in Cancer research (Chicago, Ill.) (01.03.1994)
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Measurement of serum L-asparagine in the presence of L-asparaginase requires the presence of an L-asparaginase inhibitor
ASSELIN, B. L, LORENSON, M. Y, WHITIN, J. C, COPPOLA, D. J, KENDE, A. S, BLAKLEY, R. L, COHEN, H. J
Published in Cancer research (Chicago, Ill.) (15.12.1991)
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Published in Cancer research (Chicago, Ill.) (15.12.1991)
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Dissociation constants for dihydrofolic acid and dihydrobiopterin and implications for mechanistic models for dihydrofolate reductase
Maharaj, Geeta, Selinsky, Barry S, Appleman, James R, Perlman, Michael, London, Robert E, Blakley, Raymond L
Published in Biochemistry (Easton) (01.05.1990)
Published in Biochemistry (Easton) (01.05.1990)
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Biochemical pharmacology of 2-chlorodeoxyadenosine in malignant human hematopoietic cell lines and therapeutic effects of 2-bromodeoxyadenosine in drug combinations in mice
AVERY, T. L, REHG, J. E, LUMM, W. C, HARWOOD, F. C, SANTANA, V. M, BLAKLEY, R. L
Published in Cancer research (Chicago, Ill.) (15.09.1989)
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Published in Cancer research (Chicago, Ill.) (15.09.1989)
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Titration of histidine 62 in R67 dihydrofolate reductase is linked to a tetramer .tautm. two-dimer equilibrium
Nichols, Robert, Weaver, C. David, Eisenstein, Edward, Blakley, Raymond L, Appleman, James, Huang, Tai Huang, Huang, Fu Yung, Howell, Elizabeth E
Published in Biochemistry (Easton) (01.02.1993)
Published in Biochemistry (Easton) (01.02.1993)
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Methotrexate-resistant Variants of Human Dihydrofolate Reductase with Substitutions of Leucine 22
Lewis, William S., Cody, Vivian, Galitsky, Nikolai, Luft, Joseph R., Pangborn, Walter, Chunduru, Srinivas K., Spencer, H. Trent, Appleman, James R., Blakley, Raymond L.
Published in The Journal of biological chemistry (10.03.1995)
Published in The Journal of biological chemistry (10.03.1995)
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Effect of enzyme and ligand protonation on the binding of folates to recombinant human dihydrofolate reductase: implications for the evolution of eukaryotic enzyme efficiency
Appleman, James R, Tsay, Jiu Tsair, Freisheim, James H, Blakley, Raymond L
Published in Biochemistry (Easton) (14.04.1992)
Published in Biochemistry (Easton) (14.04.1992)
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Role of the conserved active site residue tryptophan-24 of human dihydrofolate reductase as revealed by mutagenesis
Beard, William A, Appleman, James R, Huang, Shaoming, Delcamp, Tavner J, Freisheim, James H, Blakley, Raymond L
Published in Biochemistry (Easton) (05.02.1991)
Published in Biochemistry (Easton) (05.02.1991)
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Kinetic investigation of the functional role of phenylalanine-31 of recombinant human dihydrofolate reductase
Tsay, Jiu Tsair, Appleman, James R, Beard, William A, Prendergast, Neal J, Delcamp, Tavner J, Freisheim, James H, Blakley, Raymond L
Published in Biochemistry (Easton) (10.07.1990)
Published in Biochemistry (Easton) (10.07.1990)
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