Extensive DNA mimicry by the ArdA anti-restriction protein and its role in the spread of antibiotic resistance
McMahon, Stephen A, Roberts, Gareth A, Johnson, Kenneth A, Cooper, Laurie P, Liu, Huanting, White, John H, Carter, Lester G, Sanghvi, Bansi, Oke, Muse, Walkinshaw, Malcolm D, Blakely, Garry W, Naismith, James H, Dryden, David T.F
Published in Nucleic acids research (01.08.2009)
Published in Nucleic acids research (01.08.2009)
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Twenty-eight divergent polysaccharide loci specifying within- and amongst-strain capsule diversity in three strains of Bacteroides fragilis
Patrick, Sheila, Blakely, Garry W, Houston, Simon, Moore, Jane, Abratt, Valerie R, Bertalan, Marcelo, Cerdeño-Tárraga, Ana M, Quail, Michael A, Corton, Nicola, Corton, Craig, Bignell, Alexandra, Barron, Andrew, Clark, Louise, Bentley, Stephen D, Parkhill, Julian
Published in Microbiology (Society for General Microbiology) (01.11.2010)
Published in Microbiology (Society for General Microbiology) (01.11.2010)
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Journal Article
Mutational analysis of genes implicated in LPS and capsular polysaccharide biosynthesis in the opportunistic pathogen Bacteroides fragilis
Patrick, Sheila, Houston, Simon, Thacker, Zubin, Blakely, Garry W
Published in Microbiology (Society for General Microbiology) (01.04.2009)
Published in Microbiology (Society for General Microbiology) (01.04.2009)
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Journal Article
Generation of Markerless Deletions in the Nosocomial Pathogen Clostridium difficile by Induction of DNA Double-Strand Breaks
Theophilou, Elena-Stella, Vohra, Prerna, Gallagher, Maurice P, Poxton, Ian R, Blakely, Garry W
Published in Applied and environmental microbiology (01.02.2019)
Published in Applied and environmental microbiology (01.02.2019)
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Journal Article
Binding and degradation of fibrinogen by Bacteroides fragilis and characterization of a 54 kDa fibrinogen-binding protein
HOUSTON, Simon, BLAKELY, Garry W, MCDOWELL, Andrew, MARTIN, Lorraine, PATRICK, Sheila
Published in Microbiology (Society for General Microbiology) (01.08.2010)
Published in Microbiology (Society for General Microbiology) (01.08.2010)
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Journal Article
Exploring the DNA mimicry of the Ocr protein of phage T7
Roberts, Gareth A, Stephanou, Augoustinos S, Kanwar, Nisha, Dawson, Angela, Cooper, Laurie P, Chen, Kai, Nutley, Margaret, Cooper, Alan, Blakely, Garry W, Dryden, David T F
Published in Nucleic acids research (01.09.2012)
Published in Nucleic acids research (01.09.2012)
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Journal Article
structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro
Serfiotis-Mitsa, Dimitra, Herbert, Andrew P, Roberts, Gareth A, Soares, Dinesh C, White, John H, Blakely, Garry W, Uhrín, Dušan, Dryden, David T.F
Published in Nucleic acids research (01.03.2010)
Published in Nucleic acids research (01.03.2010)
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Journal Article
ArdA proteins from different mobile genetic elements can bind to the EcoKI Type I DNA methyltransferase of E. coli K12
Chen, Kai, Reuter, Marcel, Sanghvi, Bansi, Roberts, Gareth A., Cooper, Laurie P., Tilling, Matthew, Blakely, Garry W., Dryden, David T.F.
Published in Biochimica et biophysica acta (01.03.2014)
Published in Biochimica et biophysica acta (01.03.2014)
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A unique homologue of the eukaryotic protein-modifier ubiquitin present in the bacterium Bacteroides fragilis, a predominant resident of the human gastrointestinal tract
PATRICK, Sheila, JOBLING, Kelly L, O'CONNOR, Danny, THACKER, Zubin, DRYDEN, David T. F, BLAKELY, Garry W
Published in Microbiology (Society for General Microbiology) (01.11.2011)
Published in Microbiology (Society for General Microbiology) (01.11.2011)
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Removal of a frameshift between the hsdM and hsdS genes of the EcoKI Type IA DNA restriction and modification system produces a new type of system and links the different families of Type I systems
Roberts, Gareth A, Chen, Kai, Cooper, Laurie P, White, John H, Blakely, Garry W, Dryden, David T F
Published in Nucleic acids research (01.11.2012)
Published in Nucleic acids research (01.11.2012)
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Journal Article
Mutations of the domain forming the dimeric interface of the ArdA protein affect dimerization and antimodification activity but not antirestriction activity
Roberts, Gareth A., Chen, Kai, Bower, Edward K. M., Madrzak, Julia, Woods, Arcadia, Barker, Amy M., Cooper, Laurie P., White, John H., Blakely, Garry W., Manfield, Iain, Dryden, David T. F.
Published in The FEBS journal (01.10.2013)
Published in The FEBS journal (01.10.2013)
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The Orf18 gene product from conjugative transposon Tn916 is an ArdA antirestriction protein that inhibits type I DNA restriction-modification systems
Serfiotis-Mitsa, Dimitra, Roberts, Gareth A, Cooper, Laurie P, White, John H, Nutley, Margaret, Cooper, Alan, Blakely, Garry W, Dryden, David T F
Published in Journal of molecular biology (28.11.2008)
Published in Journal of molecular biology (28.11.2008)
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