Neurofilament light protein in blood as a potential biomarker of neurodegeneration in Huntington's disease: a retrospective cohort analysis
Byrne, Lauren M, MRes, Rodrigues, Filipe B, MD, Blennow, Kaj, Prof, Durr, Alexandra, Prof, Leavitt, Blair R, Prof, Roos, Raymund A C, Prof, Scahill, Rachael I, PhD, Tabrizi, Sarah J, Prof, Zetterberg, Henrik, Prof, Langbehn, Douglas, Prof, Wild, Edward J, Dr
Published in Lancet neurology (01.08.2017)
Published in Lancet neurology (01.08.2017)
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Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data
Tabrizi, Sarah J, Prof, Scahill, Rachael I, PhD, Owen, Gail, PhD, Durr, Alexandra, MD, Leavitt, Blair R, MDCM, Roos, Raymund A, Prof, Borowsky, Beth, PhD, Landwehrmeyer, Bernhard, Prof, Frost, Chris, Prof, Johnson, Hans, PhD, Craufurd, David, MD, Reilmann, Ralf, MD, Stout, Julie C, Prof, Langbehn, Douglas R, Prof
Published in Lancet neurology (01.07.2013)
Published in Lancet neurology (01.07.2013)
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Huntington disease: natural history, biomarkers and prospects for therapeutics
Ross, Christopher A., Aylward, Elizabeth H., Wild, Edward J., Langbehn, Douglas R., Long, Jeffrey D., Warner, John H., Scahill, Rachael I., Leavitt, Blair R., Stout, Julie C., Paulsen, Jane S., Reilmann, Ralf, Unschuld, Paul G., Wexler, Alice, Margolis, Russell L., Tabrizi, Sarah J.
Published in Nature reviews. Neurology (01.04.2014)
Published in Nature reviews. Neurology (01.04.2014)
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Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis
Tabrizi, Sarah J, Prof, Scahill, Rachael I, PhD, Durr, Alexandra, MD, Roos, Raymund AC, MD, Leavitt, Blair R, FRCPC, Jones, Rebecca, MSc, Landwehrmeyer, G Bernhard, MD, Fox, Nick C, MD, Johnson, Hans, PhD, Hicks, Stephen L, PhD, Kennard, Christopher, FRCP, Craufurd, David, FRCPsych, Frost, Chris, PhD, Langbehn, Douglas R, MD, Reilmann, Ralf, MD, Stout, Julie C, PhD
Published in Lancet neurology (2011)
Published in Lancet neurology (2011)
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Development of biomarkers for Huntington's disease
Weir, David W, BSc, Sturrock, Aaron, MBBS, Leavitt, Blair R, MDCM
Published in Lancet neurology (01.06.2011)
Published in Lancet neurology (01.06.2011)
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Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticles
Kulkarni, Jayesh A, Thomson, Sarah B, Zaifman, Josh, Leung, Jerry, Wagner, Pamela K, Hill, Austin, Tam, Yuen Yi C, Cullis, Pieter R, Petkau, Terri L, Leavitt, Blair R
Published in Nanoscale (21.12.2020)
Published in Nanoscale (21.12.2020)
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Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data
Tabrizi, Sarah J, Langbehn, Douglas R, Leavitt, Blair R, Roos, Raymund AC, Durr, Alexandra, Craufurd, David, Kennard, Christopher, Hicks, Stephen L, Fox, Nick C, Scahill, Rachael I, Borowsky, Beth, Tobin, Allan J, Rosas, H Diana, Johnson, Hans, Reilmann, Ralf, Landwehrmeyer, Bernhard, Stout, Julie C
Published in Lancet neurology (01.09.2009)
Published in Lancet neurology (01.09.2009)
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Intracerebroventricular Administration of AAV9-PHP.B SYN1-EmGFP Induces Widespread Transgene Expression in the Mouse and Monkey Central Nervous System
Galvan, Adriana, Petkau, Terri L, Hill, Austin M, Korecki, Andrea J, Lu, Ge, Choi, Diane, Rahman, Kazi, Simpson, Elizabeth M, Leavitt, Blair R, Smith, Yoland
Published in Human gene therapy (01.06.2021)
Published in Human gene therapy (01.06.2021)
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The clinical and genetic features of Huntington disease
Sturrock, Aaron, Leavitt, Blair R
Published in Journal of geriatric psychiatry and neurology (01.12.2010)
Published in Journal of geriatric psychiatry and neurology (01.12.2010)
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FTD-associated behavioural and transcriptomic abnormalities in ‘humanized’ progranulin-deficient mice: A novel model for progranulin-associated FTD
Life, Benjamin, Petkau, Terri L., Cruz, Giuliano N.F., Navarro-Delgado, Erick I., Shen, Ning, Korthauer, Keegan, Leavitt, Blair R.
Published in Neurobiology of disease (15.06.2023)
Published in Neurobiology of disease (15.06.2023)
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Journal Article
Potential biomarkers to follow the progression and treatment response of Huntington's disease
Disatnik, Marie-Hélène, Joshi, Amit U, Saw, Nay L, Shamloo, Mehrdad, Leavitt, Blair R, Qi, Xin, Mochly-Rosen, Daria
Published in The Journal of experimental medicine (14.11.2016)
Published in The Journal of experimental medicine (14.11.2016)
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A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
Björkqvist, Maria, Wild, Edward J, Thiele, Jenny, Silvestroni, Aurelio, Andre, Ralph, Lahiri, Nayana, Raibon, Elsa, Lee, Richard V, Benn, Caroline L, Soulet, Denis, Magnusson, Anna, Woodman, Ben, Landles, Christian, Pouladi, Mahmoud A, Hayden, Michael R, Khalili-Shirazi, Azadeh, Lowdell, Mark W, Brundin, Patrik, Bates, Gillian P, Leavitt, Blair R, Möller, Thomas, Tabrizi, Sarah J
Published in The Journal of experimental medicine (04.08.2008)
Published in The Journal of experimental medicine (04.08.2008)
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Operationalizing compensation over time in neurodegenerative disease
Gregory, Sarah, Long, Jeffrey D, Klöppel, Stefan, Razi, Adeel, Scheller, Elisa, Minkova, Lora, Papoutsi, Marina, Mills, James A, Durr, Alexandra, Leavitt, Blair R, Roos, Raymund A C, Stout, Julie C, Scahill, Rachael I, Langbehn, Douglas R, Tabrizi, Sarah J, Rees, Geraint
Published in Brain (London, England : 1878) (01.04.2017)
Published in Brain (London, England : 1878) (01.04.2017)
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Journal Article
Brain Regions Showing White Matter Loss in Huntington’s Disease Are Enriched for Synaptic and Metabolic Genes
McColgan, Peter, Gregory, Sarah, Seunarine, Kiran K., Razi, Adeel, Papoutsi, Marina, Johnson, Eileanoir, Durr, Alexandra, Roos, Raymund A.C., Leavitt, Blair R., Holmans, Peter, Scahill, Rachael I., Clark, Chris A., Rees, Geraint, Tabrizi, Sarah J., Coleman, A., Decolongon, J., Fan, M., Petkau, T., Jauffret, C., Justo, D., Lehericy, S., Nigaud, K., Valabrègue, R., Schoonderbeek, A., ‘t Hart, E.P., Moss, D. J. Hensman, Ghosh, R., Crawford, H., Papoutsi, M., Berna, C., Mahaleskshmi, D., Reilmann, R., Weber, N., Labuschagne, I., Stout, J., Landwehrmeyer, B., Orth, M., Mayer, I., Johnson, H., Crawfurd, D.
Published in Biological psychiatry (1969) (01.03.2018)
Published in Biological psychiatry (1969) (01.03.2018)
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A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes
Ciosi, Marc, Maxwell, Alastair, Cumming, Sarah A., Hensman Moss, Davina J., Alshammari, Asma M., Flower, Michael D., Durr, Alexandra, Leavitt, Blair R., Roos, Raymund A.C., Holmans, Peter, Jones, Lesley, Langbehn, Douglas R., Kwak, Seung, Tabrizi, Sarah J., Monckton, Darren G.
Published in EBioMedicine (01.10.2019)
Published in EBioMedicine (01.10.2019)
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Human progranulin-expressing mice as a novel tool for the development of progranulin-modulating therapeutics
Petkau, Terri L., Life, Benjamin, Lu, Ge, Yang, Jasmine, Fornes, Oriol, Wasserman, Wyeth, Simpson, Elizabeth M., Leavitt, Blair R.
Published in Neurobiology of disease (01.06.2021)
Published in Neurobiology of disease (01.06.2021)
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Selective depletion of microglial progranulin in mice is not sufficient to cause neuronal ceroid lipofuscinosis or neuroinflammation
Petkau, Terri L, Kosior, Natalia, de Asis, Kathleen, Connolly, Colúm, Leavitt, Blair R
Published in Journal of neuroinflammation (17.11.2017)
Published in Journal of neuroinflammation (17.11.2017)
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Synaptic dysfunction in progranulin-deficient mice
Petkau, Terri L, Neal, Scott J, Milnerwood, Austen, Mew, Ada, Hill, Austin M, Orban, Paul, Gregg, Jenny, Lu, Ge, Feldman, Howard H, Mackenzie, Ian R.A, Raymond, Lynn A, Leavitt, Blair R
Published in Neurobiology of disease (01.02.2012)
Published in Neurobiology of disease (01.02.2012)
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