The Varied Roles of Notch in Cancer
Aster, Jon C, Pear, Warren S, Blacklow, Stephen C
Published in Annual review of pathology (24.01.2017)
Published in Annual review of pathology (24.01.2017)
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Journal Article
Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch
Gordon, Wendy R., Zimmerman, Brandon, He, Li, Miles, Laura J., Huang, Jiuhong, Tiyanont, Kittichoat, McArthur, Debbie G., Aster, Jon C., Perrimon, Norbert, Loparo, Joseph J., Blacklow, Stephen C.
Published in Developmental cell (22.06.2015)
Published in Developmental cell (22.06.2015)
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Journal Article
Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket
Zimmerman, Brandon, Kelly, Brendan, McMillan, Brian J., Seegar, Tom C.M., Dror, Ron O., Kruse, Andrew C., Blacklow, Stephen C.
Published in Cell (03.11.2016)
Published in Cell (03.11.2016)
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Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition
LaRochelle, Jonathan R., Fodor, Michelle, Vemulapalli, Vidyasiri, Mohseni, Morvarid, Wang, Ping, Stams, Travis, LaMarche, Matthew J., Chopra, Rajiv, Acker, Michael G., Blacklow, Stephen C.
Published in Nature communications (30.10.2018)
Published in Nature communications (30.10.2018)
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Journal Article
Structural Basis for Substrate Selectivity of the E3 Ligase COP1
Uljon, Sacha, Xu, Xiang, Durzynska, Izabela, Stein, Sarah, Adelmant, Guillaume, Marto, Jarrod A., Pear, Warren S., Blacklow, Stephen C.
Published in Structure (London) (03.05.2016)
Published in Structure (London) (03.05.2016)
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Journal Article
Design of biologically active binary protein 2D materials
Ben-Sasson, Ariel J., Watson, Joseph L., Sheffler, William, Johnson, Matthew Camp, Bittleston, Alice, Somasundaram, Logeshwaran, Decarreau, Justin, Jiao, Fang, Chen, Jiajun, Mela, Ioanna, Drabek, Andrew A., Jarrett, Sanchez M., Blacklow, Stephen C., Kaminski, Clemens F., Hura, Greg L., De Yoreo, James J., Kollman, Justin M., Ruohola-Baker, Hannele, Derivery, Emmanuel, Baker, David
Published in Nature (London) (21.01.2021)
Published in Nature (London) (21.01.2021)
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Journal Article
NOTCH1–RBPJ complexes drive target gene expression through dynamic interactions with superenhancers
Wang, Hongfang, Zang, Chongzhi, Taing, Len, Arnett, Kelly L., Wong, Yinling Joey, Pear, Warren S., Blacklow, Stephen C., Liu, Shirley, Aster, Jon C.
Published in Proceedings of the National Academy of Sciences - PNAS (14.01.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (14.01.2014)
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Journal Article
Pharmacological disruption of the Notch transcription factor complex
Lehal, Rajwinder, Zaric, Jelena, Vigolo, Michele, Urech, Charlotte, Frismantas, Viktoras, Zangger, Nadine, Cao, Linlin, Berger, Adeline, Chicote, Irene, Loubéry, Sylvain, Choi, Sung Hee, Koch, Ute, Blacklow, Stephen C., Palmer, Hector G., Bornhauser, Beat, González-Gaitán, Marcos, Arsenijevic, Yvan, Zoete, Vincent, Aster, Jon C., Bourquin, Jean-Pierre, Radtke, Freddy
Published in Proceedings of the National Academy of Sciences - PNAS (14.07.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (14.07.2020)
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Journal Article
molecular logic of Notch signaling - a structural and biochemical perspective
Gordon, Wendy R, Arnett, Kelly L, Blacklow, Stephen C
Published in Journal of cell science (01.10.2008)
Published in Journal of cell science (01.10.2008)
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Journal Article
Direct inhibition of the NOTCH transcription factor complex
Moellering, Raymond E., Cornejo, Melanie, Davis, Tina N., Bianco, Cristina Del, Aster, Jon C., Blacklow, Stephen C., Kung, Andrew L., Gilliland, D. Gary, Verdine, Gregory L., Bradner, James E.
Published in Nature (London) (12.11.2009)
Published in Nature (London) (12.11.2009)
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Journal Article
T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling
Germar, Kristine, Dose, Marei, Konstantinou, Tassos, Zhang, Jiangwen, Wang, Hongfang, Lobry, Camille, Arnett, Kelly L, Blacklow, Stephen C, Aifantis, Iannis, Aster, Jon C, Gounari, Fotini
Published in Proceedings of the National Academy of Sciences - PNAS (13.12.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (13.12.2011)
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Journal Article
Complementary Genomic Screens Identify SERCA as a Therapeutic Target in NOTCH1 Mutated Cancer
Roti, Giovanni, Carlton, Anne, Ross, Kenneth N., Markstein, Michele, Pajcini, Kostandin, Su, Angela H., Perrimon, Norbert, Pear, Warren S., Kung, Andrew L., Blacklow, Stephen C., Aster, Jon C., Stegmaier, Kimberly
Published in Cancer cell (18.03.2013)
Published in Cancer cell (18.03.2013)
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Journal Article
Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells
Wang, Hongfang, Zou, James, Zhao, Bo, Johannsen, Eric, Ashworth, Todd, Wong, Hoifung, Pear, Warren S, Schug, Jonathan, Blacklow, Stephen C, Arnett, Kelly L, Bernstein, Bradley E, Kieff, Elliott, Aster, Jon C
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2011)
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Journal Article
Intrinsic Selectivity of Notch 1 for Delta-like 4 Over Delta-like 1
Andrawes, Marie Blanke, Xu, Xiang, Liu, Hong, Ficarro, Scott B., Marto, Jarrod A., Aster, Jon C., Blacklow, Stephen C.
Published in The Journal of biological chemistry (30.08.2013)
Published in The Journal of biological chemistry (30.08.2013)
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Journal Article
Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia
Yashiro-Ohtani, Yumi, Wang, Hongfang, Zang, Chongzhi, Arnett, Kelly L, Bailis, Will, Ho, Yugong, Knoechel, Birgit, Lanauze, Claudia, Louis, Lumena, Forsyth, Katherine S, Chen, Sujun, Chung, Yoonjie, Schug, Jonathan, Blobel, Gerd A, Liebhaber, Stephen A, Bernstein, Bradley E, Blacklow, Stephen C, Liu, Xiaole Shirley, Aster, Jon C, Pear, Warren S
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2014)
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Journal Article
Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma
Wang, Nicholas J, Sanborn, Zachary, Arnett, Kelly L, Bayston, Laura J, Liao, Wilson, Proby, Charlotte M, Leigh, Irene M, Collisson, Eric A, Gordon, Patricia B, Jakkula, Lakshmi, Pennypacker, Sally, Zou, Yong, Sharma, Mimansa, North, Jeffrey P, Vemula, Swapna S, Mauro, Theodora M, Neuhaus, Isaac M, LeBoit, Philip E, Hur, Joe S, Park, Kyunghee, Huh, Nam, Kwok, Pui-Yan, Arron, Sarah T, Massion, Pierre P, Bale, Allen E, Haussler, David, Cleaver, James E, Gray, Joe W, Spellman, Paul T, South, Andrew P, Aster, Jon C, Blacklow, Stephen C, Cho, Raymond J
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2011)
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Journal Article
Notch signaling in leukemia
Aster, Jon C, Pear, Warren S, Blacklow, Stephen C
Published in Annual review of pathology (01.01.2008)
Published in Annual review of pathology (01.01.2008)
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