Golexanolone reduces glial activation in the striatum and improves non-motor and some motor alterations in a rat model of Parkinson's disease
Izquierdo-Altarejos, Paula, Arenas, Yaiza M, Martínez-García, Mar, Vázquez, Lola, Mincheva, Gergana, Doverskog, Magnus, Blackburn, Thomas P, Bohnen, Nicolaas I, Llansola, Marta, Felipo, Vicente
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Published in Frontiers in aging neuroscience (21.06.2024)
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Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist
Forray, Carlos, Borowsky, Beth, Durkin, Margaret M, Ogozalek, Kristine, Marzabadi, Mohammad R, DeLeon, John, Heurich, Rainer, Lichtblau, Harvey, Shaposhnik, Zoya, Daniewska, Irena, Blackburn, Thomas P, Branchek, Theresa A, Gerald, Christophe, Vaysse, Pierre J
Published in Nature medicine (01.08.2002)
Published in Nature medicine (01.08.2002)
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Anxiolytic- and Antidepressant-like Profiles of the Galanin-3 Receptor ($Gal_3$) Antagonists SNAP 37889 and SNAP 398299
Chad J. Swanson, Thomas P. Blackburn, Xuexiang Zhang, Zheng, Kang, Xu, Zhi-Qing David, Hökfelt, Tomas, Toni D. Wolinsky, Michael J. Konkel, Heidi Chen, Huailing Zhong, Mary W. Walker, Craig, Douglas A., Christophe P. G. Gerald, Branchek, Theresa A.
Published in Proceedings of the National Academy of Sciences - PNAS (29.11.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (29.11.2005)
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Selecting Double Bond Positions with a Single Cation-Responsive Iridium Olefin Isomerization Catalyst
Camp, Andrew M, Kita, Matthew R, Blackburn, P. Thomas, Dodge, Henry M, Chen, Chun-Hsing, Miller, Alexander J. M
Published in Journal of the American Chemical Society (24.02.2021)
Published in Journal of the American Chemical Society (24.02.2021)
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Golexanolone, a GABAA receptor modulating steroid antagonist, restores motor coordination and cognitive function in hyperammonemic rats by dual effects on peripheral inflammation and neuroinflammation
Mincheva, Gergana, Gimenez‐Garzo, Carla, Izquierdo‐Altarejos, Paula, Martinez‐Garcia, Mar, Doverskog, Magnus, Blackburn, Thomas P., Hällgren, Anneli, Bäckström, Torbjörn, Llansola, Marta, Felipo, Vicente
Published in CNS neuroscience & therapeutics (01.11.2022)
Published in CNS neuroscience & therapeutics (01.11.2022)
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In memory of Norman Bowery (1944–2016)
Trist, David G, Kenakin, Terry P, Blackburn, Thomas P
Published in Current opinion in pharmacology (01.08.2017)
Published in Current opinion in pharmacology (01.08.2017)
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The promise of molecular science in brain health. What breakthroughs are anticipated in the next 20 years?
Hainsworth, Atticus H, Blackburn, Thomas P, Bradshaw, Elizabeth M, Elahi, Fanny M, Gorelick, Philip B, Isaacs, Jeremy D, Wallin, Anders, Williams, Steven CR
Published in Cerebral circulation - cognition and behavior (2024)
Published in Cerebral circulation - cognition and behavior (2024)
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The medical benefit of 5-HT research
Jones, Brian J, Blackburn, Thomas P
Published in Pharmacology, biochemistry and behavior (01.04.2002)
Published in Pharmacology, biochemistry and behavior (01.04.2002)
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Acute and repeated administration of fluoxetine, citalopram, and paroxetine significantly alters the activity of midbrain dopamine neurons in rats: An in vivo electrophysiological study
Sekine, Yoshimoto, Suzuki, Katsuaki, Ramachandran, P. Veeraraghavan, Blackburn, Thomas P., Ashby JR, Charles R.
Published in Synapse (New York, N.Y.) (01.02.2007)
Published in Synapse (New York, N.Y.) (01.02.2007)
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3-Arylimino-2-indolones Are Potent and Selective Galanin GAL3 Receptor Antagonists
Konkel, Michael J, Lagu, Bharat, Boteju, Lakmal W, Jimenez, Hermogenes, Noble, Stewart, Walker, Mary W, Chandrasena, Gamini, Blackburn, Thomas P, Nikam, Sham S, Wright, Jon L, Kornberg, Brian E, Gregory, Tracy, Pugsley, Thomas A, Akunne, Hyacinth, Zoski, Kim, Wise, Lawrence D
Published in Journal of medicinal chemistry (29.06.2006)
Published in Journal of medicinal chemistry (29.06.2006)
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5-ht6 receptors as emerging targets for drug discovery
Branchek, T A, Blackburn, T P
Published in Annual review of pharmacology and toxicology (01.01.2000)
Published in Annual review of pharmacology and toxicology (01.01.2000)
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6-Chloro-5-methyl-1-[[2-[(2-methyl-3- pyridyl)oxy]-5-pyridyl]carbamoyl]indoline (SB-242084): The First Selective and Brain Penetrant 5-HT2C Receptor Antagonist
Bromidge, Steven M, Duckworth, Malcolm, Forbes, Ian T, Ham, Peter, King, Frank D, Thewlis, Kevin M, Blaney, Frank E, Naylor, Christopher B, Blackburn, Thomas P, Kennett, Guy A, Wood, Martyn D, Clarke, Stephen E
Published in Journal of medicinal chemistry (24.10.1997)
Published in Journal of medicinal chemistry (24.10.1997)
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