Eosinophilic and Noneosinophilic Asthma: An Expert Consensus Framework to Characterize Phenotypes in a Global Real-Life Severe Asthma Cohort
Heaney, Liam G, Perez de Llano, Luis, Al-Ahmad, Mona, Backer, Vibeke, Busby, John, Canonica, Giorgio Walter, Christoff, George C, Cosio, Borja G, FitzGerald, J Mark, Heffler, Enrico, Iwanaga, Takashi, Jackson, David J, Menzies-Gow, Andrew N, Papadopoulos, Nikolaos G, Papaioannou, Andriana I, Pfeffer, Paul E, Popov, Todor A, Porsbjerg, Celeste M, Rhee, Chin Kook, Sadatsafavi, Mohsen, Tohda, Yuji, Wang, Eileen, Wechsler, Michael E, Alacqua, Marianna, Altraja, Alan, Bjermer, Leif, Björnsdóttir, Unnur S, Bourdin, Arnaud, Brusselle, Guy G, Buhl, Roland, Costello, Richard W, Hew, Mark, Koh, Mariko Siyue, Lehmann, Sverre, Lehtimäki, Lauri, Peters, Matthew, Taillé, Camille, Taube, Christian, Tran, Trung N, Zangrilli, James, Bulathsinhala, Lakmini, Carter, Victoria A, Chaudhry, Isha, Eleangovan, Neva, Hosseini, Naeimeh, Kerkhof, Marjan, Murray, Ruth B, Price, Chris A, Price, David B
Published in Chest (01.09.2021)
Published in Chest (01.09.2021)
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Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations
Aguillo, Esperanza, Kristvinsson, Hoskuldur, Sigurdsson, Asgeir, Jakobsdottir, Margret, Jonsson, Thorvaldur, Frigge, Michael L, Li, Wei, Kristjansson, Kristleifur, Helgadottir, Hafdis, Geller, Frank, Blondal, Thorarinn, Magnusdottir, Droplaug N, Prats, Enrique, Bergthorsson, Jon T, Nagy, Rebecca, Martinez, Mariano, Stacey, Simon N, Eyjolfsson, Gudmundur I, Gudbjartsson, Daniel F, Saez, Berta, Gulcher, Jeffrey R, Gudmundsson, Julius, Kong, Augustine, Hrafnkelsson, Jon, Sulem, Patrick, Jonasson, Jon G, He, Huiling, Matthiasdottir, Sigurborg, Rafnar, Thorunn, Stefansson, Kari, Thorsteinsdottir, Unnur, Bjornsdottir, Unnur S, Mayordomo, Jose I, de la Chapelle, Albert, Holm, Hilma, Skarphedinsson, Oskar B, Faure, Eduardo, Hjartarsson, Hannes
Published in Nature genetics (01.04.2009)
Published in Nature genetics (01.04.2009)
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Sequence variants influencing the regulation of serum IgG subclass levels
Olafsdottir, Thorunn A., Thorleifsson, Gudmar, Lopez de Lapuente Portilla, Aitzkoa, Jonsson, Stefan, Stefansdottir, Lilja, Niroula, Abhishek, Jonasdottir, Aslaug, Eggertsson, Hannes P., Halldorsson, Gisli H., Thorlacius, Gudny E., Arnthorsson, Asgeir O., Bjornsdottir, Unnur S., Asselbergs, Folkert W., Bentlage, Arthur E. H., Eyjolfsson, Gudmundur I., Gudmundsdottir, Steinunn, Gunnarsdottir, Kristbjorg, Halldorsson, Bjarni V., Holm, Hilma, Ludviksson, Bjorn R., Melsted, Pall, Norddahl, Gudmundur L., Olafsson, Isleifur, Saevarsdottir, Saedis, Sigurdardottir, Olof, Sigurdsson, Asgeir, Temming, Robin, Önundarson, Pall T., Thorsteinsdottir, Unnur, Vidarsson, Gestur, Sulem, Patrick, Gudbjartsson, Daniel F., Jonsdottir, Ingileif, Nilsson, Björn, Stefansson, Kari
Published in Nature communications (14.09.2024)
Published in Nature communications (14.09.2024)
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Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases
Gudbjartsson, Daniel F, Holm, Hilma, Indridason, Olafur S, Thorleifsson, Gudmar, Edvardsson, Vidar, Sulem, Patrick, de Vegt, Femmie, d'Ancona, Frank C H, den Heijer, Martin, Wetzels, Jack F M, Franzson, Leifur, Rafnar, Thorunn, Kristjansson, Kristleifur, Bjornsdottir, Unnur S, Eyjolfsson, Gudmundur I, Kiemeney, Lambertus A, Kong, Augustine, Palsson, Runolfur, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in PLoS genetics (01.07.2010)
Published in PLoS genetics (01.07.2010)
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Profiling of Genes Expressed in Peripheral Blood Mononuclear Cells Predicts Glucocorticoid Sensitivity in Asthma Patients
Hakon Hakonarson, Unnur S. Bjornsdottir, Halapi, Eva, Jonathan Bradfield, Florian Zink, Magali Mouy, Hildur Helgadottir, Asta S. Gudmundsdottir, Hjalti Andrason, Asdis E. Adalsteinsdottir, Kristjansson, Kristleifur, Illugi Birkisson, Thor Arnason, Margret Andresdottir, David Gislason, Thorarinn Gislason, Gulcher, Jeffrey R., Stefansson, Kari
Published in Proceedings of the National Academy of Sciences - PNAS (11.10.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (11.10.2005)
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Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene
Kapur, Karen, Johnson, Toby, Beckmann, Noam D, Sehmi, Joban, Tanaka, Toshiko, Kutalik, Zoltán, Styrkarsdottir, Unnur, Zhang, Weihua, Marek, Diana, Gudbjartsson, Daniel F, Milaneschi, Yuri, Holm, Hilma, Diiorio, Angelo, Waterworth, Dawn, Li, Yun, Singleton, Andrew B, Bjornsdottir, Unnur S, Sigurdsson, Gunnar, Hernandez, Dena G, Desilva, Ranil, Elliott, Paul, Eyjolfsson, Gudmundur I, Guralnik, Jack M, Scott, James, Thorsteinsdottir, Unnur, Bandinelli, Stefania, Chambers, John, Stefansson, Kari, Waeber, Gérard, Ferrucci, Luigi, Kooner, Jaspal S, Mooser, Vincent, Vollenweider, Peter, Beckmann, Jacques S, Bochud, Murielle, Bergmann, Sven
Published in PLoS genetics (01.07.2010)
Published in PLoS genetics (01.07.2010)
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Discovery of common variants associated with low TSH levels and thyroid cancer risk
Gudmundsson, Julius, Sulem, Patrick, Gudbjartsson, Daniel F, Jonasson, Jon G, Masson, Gisli, He, Huiling, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Stacey, Simon N, Johannsdottir, Hrefna, Th Helgadottir, Hafdis, Li, Wei, Nagy, Rebecca, Ringel, Matthew D, Kloos, Richard T, de Visser, Marieke C H, Plantinga, Theo S, den Heijer, Martin, Aguillo, Esperanza, Panadero, Angeles, Prats, Enrique, Garcia-Castaño, Almudena, De Juan, Ana, Rivera, Fernando, Walters, G Bragi, Bjarnason, Hjordis, Tryggvadottir, Laufey, Eyjolfsson, Gudmundur I, Bjornsdottir, Unnur S, Holm, Hilma, Olafsson, Isleifur, Kristjansson, Kristleifur, Kristvinsson, Hoskuldur, T Magnusson, Olafur, Thorleifsson, Gudmar, Gulcher, Jeffrey R, Kong, Augustine, Kiemeney, Lambertus ALM, Jonsson, Thorvaldur, Hjartarson, Hannes, Mayordomo, Jose I, Netea-Maier, Romana T, de la Chapelle, Albert, Hrafnkelsson, Jon, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Nature genetics (01.03.2012)
Published in Nature genetics (01.03.2012)
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A partial loss-of-function variant in STAT6 protects against type 2 asthma
Kristjansdottir, Katla, Norddahl, Gudmundur L., Ivarsdottir, Erna V., Halldorsson, Gisli H., Einarsson, Gudmundur, Bjarnadottir, Kristbjorg, Rutsdottir, Gudrun, Arnthorsson, Asgeir O., Erikstrup, Christian, Gudmundsdottir, Steinunn, Gunnarsdottir, Kristbjorg, Gunnbjornsdottir, Maria I., Halldorsson, Bjarni V., Holm, Hilma, Ludviksdottir, Dora, Ludviksson, Bjorn R., Brunak, Søren, Bruun, Mie Topholm, Mikkelsen, Christina, Mikkelsen, Susan, Jensen, Bitten Aagaard, Sørensen, Erik, Thomsen, Simon Francis, Ullum, Henrik, Olafsson, Isleifur, Onundarson, Pall T., Ostrowski, Sisse Rye, Saevarsdottir, Saedis, Sigurdardottir, Olof, Sigurgeirsson, Bardur, Snaebjarnarson, Audunn S., Sveinbjornsson, Gardar, Thorlacius, Gudny E., Thorleifsson, Gudmar, Tragante, Vinicius, Vidarsson, Brynjar, Porsbjerg, Celeste, Bjornsdottir, Unnur S., Sulem, Patrick, Gudbjartsson, Daniel F., Melsted, Pall, Pedersen, Ole Bv, Jonsdottir, Ingileif, Olafsdottir, Thorunn A., Stefansson, Kari
Published in Journal of allergy and clinical immunology (16.10.2024)
Published in Journal of allergy and clinical immunology (16.10.2024)
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Genetic correction of PSA values using sequence variants associated with PSA levels
Gudmundsson, Julius, Besenbacher, Soren, Sulem, Patrick, Gudbjartsson, Daniel F, Olafsson, Isleifur, Arinbjarnarson, Sturla, Agnarsson, Bjarni A, Benediktsdottir, Kristrun R, Isaksson, Helgi J, Kostic, Jelena P, Gudjonsson, Sigurjon A, Stacey, Simon N, Gylfason, Arnaldur, Sigurdsson, Asgeir, Holm, Hilma, Bjornsdottir, Unnur S, Eyjolfsson, Gudmundur I, Navarrete, Sebastian, Fuertes, Fernando, Garcia-Prats, Maria D, Polo, Eduardo, Checherita, Ionel A, Jinga, Mariana, Badea, Paula, Aben, Katja K, Schalken, Jack A, van Oort, Inge M, Sweep, Fred C, Helfand, Brian T, Davis, Michael, Donovan, Jenny L, Hamdy, Freddie C, Kristjansson, Kristleifur, Gulcher, Jeffrey R, Masson, Gisli, Kong, Augustine, Catalona, William J, Mayordomo, Jose I, Geirsson, Gudmundur, Einarsson, Gudmundur V, Barkardottir, Rosa B, Jonsson, Eirikur, Jinga, Viorel, Mates, Dana, Kiemeney, Lambertus A, Neal, David E, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Science translational medicine (15.12.2010)
Published in Science translational medicine (15.12.2010)
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A sequence variant on 17q21 is associated with age at onset and severity of asthma
Halapi, Eva, Gudbjartsson, Daniel F, Jonsdottir, Gudrun M, Bjornsdottir, Unnur S, Thorleifsson, Gudmar, Helgadottir, Hafdis, Williams, Carolyn, Koppelman, Gerard H, Heinzmann, Andrea, Boezen, H Marike, Jonasdottir, Aslaug, Blondal, Thorarinn, Gudjonsson, Sigurjon A, Jonasdottir, Adalbjorg, Thorlacius, Theodora, Henry, Amanda P, Altmueller, Janine, Krueger, Marcus, Shin, Hyoung Doo, Uh, Soo-Taek, Cheong, Hyun Sub, Jonsdottir, Brynja, Ludviksson, Bjorn R, Ludviksdottir, Dora, Gislason, David, Park, Choon-Sik, Deichmann, Klaus, Thompson, Philip J, Wjst, Matthias, Hall, Ian P, Postma, Dirkje S, Gislason, Thorarinn, Kong, Augustine, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in European journal of human genetics : EJHG (01.08.2010)
Published in European journal of human genetics : EJHG (01.08.2010)
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Allelic Frequencies and Patterns of Single-nucleotide Polymorphisms in Candidate Genes for Asthma and Atopy in Iceland
HAKONARSON, HAKON, BJORNSDOTTIR, UNNUR S, OSTERMANN, ELINBORG, ARNASON, THOR, ADALSTEINSDOTTIR, ASDIS E, HALAPI, EVA, SHKOLNY, DANA, KRISTJANSSON, KRISTLEIFUR, GUDNADOTTIR, SIGURBJORG A, FRIGGE, MICHAEL L, GISLASON, DAVID, GISLASON, THORARINN, KONG, AUGUSTINE, GULCHER, JEFFREY, STEFANSSON, KARI
Published in American journal of respiratory and critical care medicine (01.12.2001)
Published in American journal of respiratory and critical care medicine (01.12.2001)
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A Major Susceptibility Gene for Asthma Maps to Chromosome 14q24
Hakonarson, Hakon, Bjornsdottir, Unnur S., Halapi, Eva, Palsson, Snaebjorn, Adalsteinsdottir, Elva, Gislason, David, Finnbogason, Gudmundur, Gislason, Thorarinn, Kristjansson, Kristleifur, Arnason, Thor, Birkisson, Illugi, Frigge, Michael L., Kong, Augustine, Gulcher, Jeffrey R., Stefansson, Kari
Published in American journal of human genetics (01.09.2002)
Published in American journal of human genetics (01.09.2002)
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Correction: Association of Variants at UMOD with Chronic Kidney Disease and Kidney Stones—Role of Age and Comorbid Diseases
Gudbjartsson, Daniel F., Holm, Hilma, Indridason, Olafur S., Thorleifsson, Gudmar, Edvardsson, Vidar, Sulem, Patrick, de Vegt, Femmie, d'Ancona, Frank C. H., den Heijer, Martin, Wetzels, Jack F. M., Franzson, Leifur, Rafnar, Thorunn, Kristjansson, Kristleifur, Bjornsdottir, Unnur S., Eyjolfsson, Gudmundur I., Kiemeney, Lambertus A., Kong, Augustine, Palsson, Runolfur, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in PLoS genetics (02.11.2010)
Published in PLoS genetics (02.11.2010)
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Genetic Approaches to Assessing Evidence for a T Helper Type 1 Cytokine Defect in Adult Asthma
Birkisson, Illugi F, Halapi, Eva, Bjornsdottir, Unnur S, Shkolny, Dana L, Adalsteinsdottir, Elva, Arnason, Thor, Gislason, David, Gislason, Thorarinn, Gulcher, Jeffrey, Stefansson, Kari, Hakonarson, Hakon
Published in American journal of respiratory and critical care medicine (01.05.2004)
Published in American journal of respiratory and critical care medicine (01.05.2004)
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A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis
Kristjansson, Ragnar P., Benonisdottir, Stefania, Davidsson, Olafur B., Oddsson, Asmundur, Tragante, Vinicius, Sigurdsson, Jon K., Stefansdottir, Lilja, Jonsson, Stefan, Jensson, Brynjar O., Arthur, Joseph G., Arnadottir, Gudny A., Sulem, Gerald, Halldorsson, Bjarni V., Gunnarsson, Bjarni, Halldorsson, Gisli H., Stefansson, Olafur A., Oskarsson, Gudjon R., Deaton, Aimee M., Olafsson, Isleifur, Eyjolfsson, Gudmundur I., Sigurdardottir, Olof, Onundarson, Pall T., Gislason, David, Gislason, Thorarinn, Ludviksson, Bjorn R., Ludviksdottir, Dora, Olafsdottir, Thorunn A., Rafnar, Thorunn, Masson, Gisli, Zink, Florian, Bjornsdottir, Gyda, Magnusson, Olafur Th, Bjornsdottir, Unnur S., Thorleifsson, Gudmar, Norddahl, Gudmundur L., Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Sulem, Patrick, Stefansson, Kari
Published in Nature genetics (01.02.2019)
Published in Nature genetics (01.02.2019)
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Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
van Rij, Andre M, Gudbjartsson, Daniel F, So, Wing Yee, Williams, Michael J A, Heinzmann, Andrea, Chan, Juliana, Pignatti, Pier Franco, Postma, Dirkje S, Olivieri, Oliviero, Gislason, Thorarinn, Boner, Attilio, Jones, Gregory T, Cheong, Hyun Sub, Ludviksdottir, Dora, Martinelli, Nicola, Malerba, Giovanni, Jonsdottir, Ingileif, Pescollderungg, Lydia, Porsbjerg, Celeste, Shin, Hyoung Doo, Trabetti, Elisabetta, Park, Choon-Sik, Backer, Vibeke, Uh, Soo-Taek, Jönsson, Ulla-Britt, Kong, Augustine, Helgadottir, Anna, James, Alan, Thorsteinsdottir, Unnur, Krueger, Marcus, Boezen, H Marike, Altmuller, Janine, Bjornsdottir, Unnur S, Stefansson, Hreinn, Hall, Ian P, Jonsdottir, Gudrun M, Ma, Ronald, Hansen, Jakob W, Thorleifsson, Gudmar, Rasmussen, Linda M, Palmer, Lyle J, Vaccarino, Viola, Wheatley, Amanda, Granger, Christopher B, Levey, Allan I, Janson, Christer, Quyyumi, Arshed A, Rader, Daniel J, Arnar, David, Reilly, Muredach P, Shah, Svati H, Hui, Jennie, Eyjolfsson, Gudmundur I, Thorgeirsson, Gudmundur, Ludviksson, Bjorn R, Gulcher, Jeffrey, Girelli, Domenico, Ng, Maggie C Y, Wjst, Matthias, Sulem, Patrick, Helgadottir, Hafdis, Deichmann, Klaus, Koppelman, Gerard H, Thompson, Philip J, Jonsdottir, Brynja, Halapi, Eva, Warrington, Nicole M, Werge, Thomas, Stefansson, Kari, Beilby, John, Gislason, David, Williams, Carolyn, Steinthorsdottir, Valgerdur
Published in Nature genetics (01.03.2009)
Published in Nature genetics (01.03.2009)
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Sequence variant affects GCSAML splicing, mast cell specific proteins, and risk of urticaria
Kristjansson, Ragnar P., Oskarsson, Gudjon R., Skuladottir, Astros, Oddsson, Asmundur, Rognvaldsson, Solvi, Sveinbjornsson, Gardar, Lund, Sigrun H., Jensson, Brynjar O., Styrmisdottir, Edda L., Halldorsson, Gisli H., Ferkingstad, Egil, Eldjarn, Grimur Hjorleifsson, Beyter, Doruk, Kristmundsdottir, Snædis, Juliusson, Kristinn, Fridriksdottir, Run, Arnadottir, Gudny A., Katrinardottir, Hildigunnur, Snorradottir, Margret H., Tragante, Vinicius, Stefansdottir, Lilja, Ivarsdottir, Erna V., Bjornsdottir, Gyda, Halldorsson, Bjarni V., Thorleifsson, Gudmar, Ludviksson, Bjorn R., Onundarson, Pall T., Saevarsdottir, Saedis, Melsted, Pall, Norddahl, Gudmundur L., Bjornsdottir, Unnur S., Olafsdottir, Thorunn, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Sulem, Patrick, Stefansson, Kari
Published in Communications biology (10.07.2023)
Published in Communications biology (10.07.2023)
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Pathways activated during human asthma exacerbation as revealed by gene expression patterns in blood
Bjornsdottir, Unnur S, Holgate, Stephen T, Reddy, Padmalatha S, Hill, Andrew A, McKee, Charlotte M, Csimma, Cristina I, Weaver, Amy A, Legault, Holly M, Small, Clayton G, Ramsey, Renee C, Ellis, Debra K, Burke, Conor M, Thompson, Philip J, Howarth, Peter H, Wardlaw, Andrew J, Bardin, Phillip G, Bernstein, David I, Irving, Louis B, Chupp, Geoffrey L, Bensch, George W, Bensch, Gregory W, Stahlman, Jon E, Karetzky, Monroe, Baker, James W, Miller, Rachel L, Goodman, Brad H, Raible, Donald G, Goldman, Samuel J, Miller, Douglas K, Ryan, John L, Dorner, Andrew J, Immermann, Frederick W, O'Toole, Margot
Published in PloS one (14.07.2011)
Published in PloS one (14.07.2011)
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Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations
Olafsson, Sigurgeir, Stridh, Pernilla, Bos, Steffan Daniël, Ingason, Andres, Euesden, Jack, Sulem, Patrick, Thorleifsson, Gudmar, Gustafsson, Omar, Johannesson, Ari, Geirsson, Arni J., Thorsson, Arni V., Sigurgeirsson, Bardur, Ludviksson, Bjorn Runar, Olafsson, Elias, Kristjansdottir, Helga, Jonasson, Jon G., Olafsson, Jon Hjaltalin, Orvar, Kjartan B., Benediktsson, Rafn, Bjarnason, Ragnar, Kristjansdottir, Sjofn, Gislason, Thorarinn, Valdimarsson, Trausti, Mikaelsdottir, Evgenia, Sigurdsson, Snaevar, Jonsson, Stefan, Rafnar, Thorunn, Aarsland, Dag, Djurovic, Srdjan, Fladby, Tormod, Knudsen, Gun Peggy, Celius, Elisabeth G., Myhr, Kjell-Morten, Grondal, Gerdur, Steinsson, Kristjan, Valdimarsson, Helgi, Bjornsson, Sigurdur, Bjornsdottir, Unnur S., Bjornsson, Einar S, Nilsson, Bjorn, Andreassen, Ole A., Alfredsson, Lars, Hillert, Jan, Kockum, Ingrid Skelton, Masson, Gisli, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Stefansson, Hreinn, Hjaltason, Haukur, Harbo, Hanne F., Olsson, Tomas, Jonsdottir, Ingileif, Stefansson, Kari
Published in Npj genomic medicine (2017)
Published in Npj genomic medicine (2017)
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Correction: Association of Variants at with Chronic Kidney Disease and Kidney Stones—Role of Age and Comorbid Diseases
Daniel F. Gudbjartsson, Hilma Holm, Olafur S. Indridason, Gudmar Thorleifsson, Vidar Edvardsson, Patrick Sulem, Femmie de Vegt, Frank C. H. d'Ancona, Martin den Heijer, Jack F. M. Wetzels, Leifur Franzson, Thorunn Rafnar, Kristleifur Kristjansson, Unnur S. Bjornsdottir, Gudmundur I. Eyjolfsson, Lambertus A. Kiemeney, Augustine Kong, Runolfur Palsson, Unnur Thorsteinsdottir, Kari Stefansson
Published in PLoS genetics (01.11.2010)
Published in PLoS genetics (01.11.2010)
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