GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity
Cichocki, Frank, Valamehr, Bahram, Bjordahl, Ryan, Zhang, Bin, Rezner, Betsy, Rogers, Paul, Gaidarova, Svetlana, Moreno, Stacey, Tuininga, Katie, Dougherty, Phillip, McCullar, Valarie, Howard, Peter, Sarhan, Dhifaf, Taras, Emily, Schlums, Heinrich, Abbot, Stewart, Shoemaker, Daniel, Bryceson, Yenan T, Blazar, Bruce R, Wolchko, Scott, Cooley, Sarah, Miller, Jeffrey S
Published in Cancer research (Chicago, Ill.) (15.10.2017)
Published in Cancer research (Chicago, Ill.) (15.10.2017)
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Journal Article
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma
Cichocki, Frank, Bjordahl, Ryan, Goodridge, Jodie P, Mahmood, Sajid, Gaidarova, Svetlana, Abujarour, Ramzey, Davis, Zachary B, Merino, Aimee, Tuininga, Katie, Wang, Hongbo, Kumar, Akhilesh, Groff, Brian, Witty, Alec, Bonello, Greg, Huffman, Janel, Dailey, Thomas, Lee, Tom T, Malmberg, Karl-Johan, Walcheck, Bruce, Höpken, Uta, Rehm, Armin, Valamehr, Bahram, Miller, Jeffrey S
Published in Nature communications (29.11.2022)
Published in Nature communications (29.11.2022)
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Journal Article
iNKT cells suppress the CD8+ T cell response to a murine Burkitt's-like B cell lymphoma
Bjordahl, Ryan L, Gapin, Laurent, Marrack, Philippa, Refaeli, Yosef
Published in PloS one (07.08.2012)
Published in PloS one (07.08.2012)
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Journal Article
CD160 activation by herpesvirus entry mediator augments inflammatory cytokine production and cytolytic function by NK cells
Šedý, John R, Bjordahl, Ryan L, Bekiaris, Vasileios, Macauley, Matthew G, Ware, Brian C, Norris, Paula S, Lurain, Nell S, Benedict, Chris A, Ware, Carl F
Published in The Journal of immunology (1950) (15.07.2013)
Published in The Journal of immunology (1950) (15.07.2013)
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Journal Article
iPSC-derived NK cells expressing high-affinity IgG Fc receptor fusion CD64/16A to mediate flexible, multi-tumor antigen targeting for lymphoma
Dixon, Kate J., Snyder, Kristin M., Khaw, Melissa, Hullsiek, Robert, Davis, Zachary B., Matson, Anders W., Shirinbak, Soheila, Hancock, Bryan, Bjordahl, Ryan, Hosking, Martin, Miller, Jeffrey S., Valamehr, Bahram, Wu, Jianming, Walcheck, Bruce
Published in Frontiers in immunology (19.07.2024)
Published in Frontiers in immunology (19.07.2024)
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Journal Article
Lymphotoxin network pathways shape the tumor microenvironment
Bjordahl, Ryan L, Steidl, Christian, Gascoyne, Randy D, Ware, Carl F
Published in Current opinion in immunology (01.04.2013)
Published in Current opinion in immunology (01.04.2013)
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Journal Article
iPSC-derived natural killer cells expressing the FcγR fusion CD64/16A can be armed with antibodies for multitumor antigen targeting
Snyder, Kristin M, Dixon, Kate J, Davis, Zachary, Hosking, Martin, Hart, Geoffrey, Khaw, Melissa, Matson, Anders, Bjordahl, Ryan, Hancock, Bryan, Shirinbak, Soheila, Miller, Jeffrey S, Valamehr, Bahram, Wu, Jianming, Walcheck, Bruce
Published in Journal for immunotherapy of cancer (06.12.2023)
Published in Journal for immunotherapy of cancer (06.12.2023)
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Journal Article
169 Off-the-shelf, engineered iPSC-derived NK cells mediate potent cytotoxic activity against primary glioblastoma cells and promote durable long-term survival in vivo
Cichocki, Frank, Ning, Jianfang, Davis, Zachary, Wang, Hongbo, Tuininga, Katie, Bjordahl, Ryan, Rogers, Paul, Ge, Moyar, Lee, Tom, Valamehr, Bob, Chen, Clark, Miller, Jeffrey
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
155 iPSC-derived NK cells mediate robust anti-tumor activity against glioblastoma
Miller, Jeffrey, Cichocki, Frank, Ning, Jianfang, Bjordahl, Ryan, Davis, Zachary, Tuininga, Katie, Wang, Hongbo, Rogers, Paul, Ge, Moyar, Lee, Tom, Valamehr, Bob, Chen, Clark
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
114 Preclinical development of a novel iPSC-derived CAR-MICA/B NK cell immunotherapy to overcome solid tumor escape from NKG2D-mediated mechanisms of recognition and killing
Goulding, John, Pribadi, Mochtar, Blum, Robert, Yeh, Wen-I, Pan, Yijia, Gaidarova, Svetlana, Chang, Chia-Wei, Chu, Hui-Yi, Liu, Ellen, Sikaroodi, Shohreh, Andrade, Lucas Ferrari de, Fong, Lauren, Huffman, Janel, Lee, Tom, Bjordahl, Ryan, Wucherpfennig, Kai, Valamehr, Bahram
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
Pluripotent stem cell–derived NK cells with high-affinity noncleavable CD16a mediate improved antitumor activity
Zhu, Huang, Blum, Robert H., Bjordahl, Ryan, Gaidarova, Svetlana, Rogers, Paul, Lee, Tom Tong, Abujarour, Ramzey, Bonello, Gregory B., Wu, Jianming, Tsai, Pei-Fang, Miller, Jeffrey S., Walcheck, Bruce, Valamehr, Bahram, Kaufman, Dan S.
Published in Blood (06.02.2020)
Published in Blood (06.02.2020)
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Journal Article
iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti-PD-1 therapy
Cichocki, Frank, Bjordahl, Ryan, Gaidarova, Svetlana, Mahmood, Sajid, Abujarour, Ramzey, Wang, Hongbo, Tuininga, Katie, Felices, Martin, Davis, Zachary B, Bendzick, Laura, Clarke, Raedun, Stokely, Laurel, Rogers, Paul, Ge, Moyar, Robinson, Megan, Rezner, Betsy, Robbins, David L, Lee, Tom T, Kaufman, Dan S, Blazar, Bruce R, Valamehr, Bahram, Miller, Jeffrey S
Published in Science translational medicine (04.11.2020)
Published in Science translational medicine (04.11.2020)
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Journal Article
Dual antigen–targeted off-the-shelf NK cells show durable response and prevent antigen escape in lymphoma and leukemia
Cichocki, Frank, Goodridge, Jodie P., Bjordahl, Ryan, Mahmood, Sajid, Davis, Zachary B., Gaidarova, Svetlana, Abujarour, Ramzey, Groff, Brian, Witty, Alec, Wang, Hongbo, Tuininga, Katie, Kodal, Behiye, Felices, Martin, Bonello, Greg, Huffman, Janel, Dailey, Thomas, Lee, Tom T., Walcheck, Bruce, Valamehr, Bahram, Miller, Jeffrey S.
Published in Blood (08.12.2022)
Published in Blood (08.12.2022)
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Journal Article
고형 종양의 유비쿼터스 표적화를 향상시키는 조작된 이펙터 세포 및 방법
GOULDING JOHN CHARLES, BJORDAHL RYAN, HOSKING MARTIN, VALAMEHR BAHRAM
Year of Publication 03.07.2024
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Year of Publication 03.07.2024
Patent
EXTH-64. IPSC-DERIVED NK CELLS EXHIBIT POTENT IN VITRO AND IN VIVO TUMORCIDAL ACTIVITY AGAINST PATIENT-DERIVED GLIOBLASTOMA STEM CELLS (GSCS)
Ning, Jianfang, Davis, Zachary, Cichocki, Frank, Wang, Hongbo, Tuininga, Katie, Bjordahl, Ryan, Lee, Tom, Miller, Jeffrey, Chen, Clark
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
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Journal Article
Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy
Woan, Karrune V., Kim, Hansol, Bjordahl, Ryan, Davis, Zachary B., Gaidarova, Svetlana, Goulding, John, Hancock, Brian, Mahmood, Sajid, Abujarour, Ramzey, Wang, Hongbo, Tuininga, Katie, Zhang, Bin, Wu, Cheng-Ying, Kodal, Behiye, Khaw, Melissa, Bendzick, Laura, Rogers, Paul, Ge, Moyar Qing, Bonello, Greg, Meza, Miguel, Felices, Martin, Huffman, Janel, Dailey, Thomas, Lee, Tom T., Walcheck, Bruce, Malmberg, Karl J., Blazar, Bruce R., Bryceson, Yenan T., Valamehr, Bahram, Miller, Jeffrey S., Cichocki, Frank
Published in Cell stem cell (02.12.2021)
Published in Cell stem cell (02.12.2021)
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Journal Article
동종이계 입양 세포 치료를 위한 보호된 이펙터 세포 및 이의 용도
WILLIAMS ALAN, BJORDAHL RYAN, GOODRIDGE JODE, MBOFUNG RINA, VALAMEHR BAHRAM
Year of Publication 07.03.2024
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Year of Publication 07.03.2024
Patent
Anti-NKG2C/IL-15/anti-CD33 killer engager directs primary and iPSC-derived NKG2C+ NK cells to target myeloid leukemia
Chiu, Emily, Felices, Martin, Cichocki, Frank, Davis, Zachary, Wang, Hongbo, Tuninga, Katie, Vallera, Daniel A., Lee, Tom, Bjordahl, Ryan, Malmberg, Karl Johan, Valamehr, Bahram, Miller, Jeffrey S.
Published in Molecular therapy (01.12.2021)
Published in Molecular therapy (01.12.2021)
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Journal Article
Alloimmune Defense Receptor Harnesses Host Immune Cell Activation to Potentiate Functional Persistence and Anti-Tumor Activity of Off-the-Shelf, Cell-Based Cancer Therapy
Williams, Alan M, Hayama, Ken L, Pan, Yijia, Groff, Brian, Mbofung, Rina M, Chang, Amber, Chen, Christine, Fong, Lauren, Brookhouser, Nicholas, Mandefro, Berhan, Abujarour, Ramzey, Lee, Tom, Mamonkin, Maksim, Clarke, Raedun, Bjordahl, Ryan, Goodridge, Jode P, Valamehr, Bahram
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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