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Published in Nature genetics (01.04.2019)
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Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination
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Published in Nature communications (07.08.2020)
Published in Nature communications (07.08.2020)
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Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases
Franzén, Oscar, Ermel, Raili, Cohain, Ariella, Akers, Nicholas K., Di Narzo, Antonio, Talukdar, Husain A., Foroughi-Asl, Hassan, Giambartolomei, Claudia, Fullard, John F., Sukhavasi, Katyayani, Köks, Sulev, Gan, Li-Ming, Giannarelli, Chiara, Kovacic, Jason C., Betsholtz, Christer, Losic, Bojan, Michoel, Tom, Hao, Ke, Roussos, Panos, Skogsberg, Josefin, Ruusalepp, Arno, Schadt, Eric E., Björkegren, Johan L. M.
Published in Science (American Association for the Advancement of Science) (19.08.2016)
Published in Science (American Association for the Advancement of Science) (19.08.2016)
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Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits
Zhang, Wen, Voloudakis, Georgios, Rajagopal, Veera M, Readhead, Ben, Dudley, Joel T, Schadt, Eric E, Björkegren, Johan L M, Kim, Yungil, Fullard, John F, Hoffman, Gabriel E, Roussos, Panos
Published in Nature communications (23.08.2019)
Published in Nature communications (23.08.2019)
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HDL and atherosclerotic cardiovascular disease: genetic insights into complex biology
Rosenson, Robert S, Brewer, Jr, H Bryan, Barter, Philip J, Björkegren, Johan L M, Chapman, M John, Gaudet, Daniel, Kim, Daniel Seung, Niesor, Eric, Rye, Kerry-Anne, Sacks, Frank M, Tardif, Jean-Claude, Hegele, Robert A
Published in Nature reviews cardiology (01.01.2018)
Published in Nature reviews cardiology (01.01.2018)
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Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade
Wang, Ying, Nanda, Vivek, Direnzo, Daniel, Ye, Jianqin, Xiao, Sophia, Kojima, Yoko, Howe, Kathryn L., Jarr, Kai-Uwe, Flores, Alyssa M., Tsantilas, Pavlos, Tsao, Noah, Rao, Abhiram, Newmane, Alexandra A. C., Eberhard, Anne V., Priest, James R., Ruusalepp, Arno, Pasterkamp, Gerard, Maegdefessel, Lars, Miller, Clint L., Lind, Lars, Koplev, Simon, Björkegren, Johan L. M., Owense, Gary K., Ingelsson, Erik, Weissmanr, Irving L., Leeper, Nicholas J.
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.2020)
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Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus
Nanda, Vivek, Wang, Ting, Pjanic, Milos, Liu, Boxiang, Nguyen, Trieu, Matic, Ljubica Perisic, Hedin, Ulf, Koplev, Simon, Ma, Lijiang, Franzén, Oscar, Ruusalepp, Arno, Schadt, Eric E, Björkegren, Johan L M, Montgomery, Stephen B, Snyder, Michael P, Quertermous, Thomas, Leeper, Nicholas J, Miller, Clint L
Published in PLoS genetics (16.11.2018)
Published in PLoS genetics (16.11.2018)
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Family-Based Approaches to Cardiovascular Health Promotion
Vedanthan, Rajesh, MD, MPH, Bansilal, Sameer, MD, MS, Soto, Ana Victoria, MD, Kovacic, Jason C., MD, PhD, Latina, Jacqueline, MD, Jaslow, Risa, MS, RDN, Santana, Maribel, BS, Gorga, Elio, MD, Kasarskis, Andrew, PhD, Hajjar, Roger, MD, Schadt, Eric E., PhD, Björkegren, Johan L., MD, PhD, Fayad, Zahi A., PhD, MSE, Fuster, Valentin, MD, PhD
Published in Journal of the American College of Cardiology (12.04.2016)
Published in Journal of the American College of Cardiology (12.04.2016)
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Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes
Li, Ling, Chen, Zhifen, von Scheidt, Moritz, Li, Shuangyue, Steiner, Andrea, Güldener, Ulrich, Koplev, Simon, Ma, Angela, Hao, Ke, Pan, Calvin, Lusis, Aldons J., Pang, Shichao, Kessler, Thorsten, Ermel, Raili, Sukhavasi, Katyayani, Ruusalepp, Arno, Gagneur, Julien, Erdmann, Jeanette, Kovacic, Jason C., Björkegren, Johan L. M., Schunkert, Heribert
Published in Basic research in cardiology (01.12.2022)
Published in Basic research in cardiology (01.12.2022)
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Functional investigation of the coronary artery disease gene SVEP1
Winkler, Michael J., Müller, Philipp, Sharifi, Amin M., Wobst, Jana, Winter, Hanna, Mokry, Michal, Ma, Lijiang, van der Laan, Sander W., Pang, Shichao, Miritsch, Benedikt, Hinterdobler, Julia, Werner, Julia, Stiller, Barbara, Güldener, Ulrich, Webb, Tom R., Asselbergs, Folkert W., Björkegren, Johan L. M., Maegdefessel, Lars, Schunkert, Heribert, Sager, Hendrik B., Kessler, Thorsten
Published in Basic research in cardiology (01.12.2020)
Published in Basic research in cardiology (01.12.2020)
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Plasma cholesterol-induced lesion networks activated before regression of early, mature, and advanced atherosclerosis
Björkegren, Johan L M, Hägg, Sara, Talukdar, Husain A, Foroughi Asl, Hassan, Jain, Rajeev K, Cedergren, Cecilia, Shang, Ming-Mei, Rossignoli, Aránzazu, Takolander, Rabbe, Melander, Olle, Hamsten, Anders, Michoel, Tom, Skogsberg, Josefin
Published in PLoS genetics (01.02.2014)
Published in PLoS genetics (01.02.2014)
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A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism
Seldin, Marcus M., Koplev, Simon, Rajbhandari, Prashant, Vergnes, Laurent, Rosenberg, Gregory M., Meng, Yonghong, Pan, Calvin, Phuong, Thuy M.N., Gharakhanian, Raffi, Che, Nam, Mäkinen, Selina, Shih, Diana M., Civelek, Mete, Parks, Brian W., Kim, Eric D., Norheim, Frode, Chella Krishnan, Karthickeyan, Hasin-Brumshtein, Yehudit, Mehrabian, Margarete, Laakso, Markku, Drevon, Christian A., Koistinen, Heikki A., Tontonoz, Peter, Reue, Karen, Cantor, Rita M., Björkegren, Johan L.M., Lusis, Aldons J.
Published in Cell metabolism (01.05.2018)
Published in Cell metabolism (01.05.2018)
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JCAD Gene at the 10p11 Coronary Artery Disease Locus Regulates Hippo Signaling in Endothelial Cells
Jones, Peter D, Kaiser, Michael A, Ghaderi Najafabadi, Maryam, Koplev, Simon, Zhao, Yuqi, Douglas, Gillian, Kyriakou, Theodosios, Andrews, Sarah, Rajmohan, Rathinasabapathy, Watkins, Hugh, Channon, Keith M, Ye, Shu, Yang, Xia, Björkegren, Johan L.M, Samani, Nilesh J, Webb, Tom R
Published in Arteriosclerosis, thrombosis, and vascular biology (01.08.2018)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.08.2018)
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Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2
Chella Krishnan, Karthickeyan, Vergnes, Laurent, Acín-Pérez, Rebeca, Stiles, Linsey, Shum, Michael, Ma, Lijiang, Mouisel, Etienne, Pan, Calvin, Moore, Timothy M, Péterfy, Miklós, Romanoski, Casey E, Reue, Karen, Björkegren, Johan L M, Laakso, Markku, Liesa, Marc, Lusis, Aldons J
Published in Nature metabolism (01.11.2021)
Published in Nature metabolism (01.11.2021)
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Rationale and Design of Family-Based Approach in a Minority Community Integrating Systems–Biology for Promotion of Health (FAMILIA)
Bansilal, Sameer, Vedanthan, Rajesh, Kovacic, Jason C., Soto, Ana Victoria, Latina, Jacqueline, Björkegren, Johan L.M., Jaslow, Risa, Santana, Maribel, Sartori, Samantha, Giannarelli, Chiara, Mani, Venkatesh, Hajjar, Roger, Schadt, Eric, Kasarskis, Andrew, Fayad, Zahi A., Fuster, Valentin
Published in The American heart journal (01.05.2017)
Published in The American heart journal (01.05.2017)
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Publisher Correction: Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination
Muhl, Lars, Genové, Guillem, Leptidis, Stefanos, Liu, Jianping, He, Liqun, Mocci, Giuseppe, Sun, Ying, Gustafsson, Sonja, Buyandelger, Byambajav, Chivukula, Indira V., Segerstolpe, Åsa, Raschperger, Elisabeth, Hansson, Emil M., Björkegren, Johan L. M., Peng, Xiao-Rong, Vanlandewijck, Michael, Lendahl, Urban, Betsholtz, Christer
Published in Nature communications (03.09.2020)
Published in Nature communications (03.09.2020)
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