Rapid and non-invasive detection of malaria parasites using near-infrared spectroscopy and machine learning
Sikulu-Lord, Maggy T, Edstein, Michael D, Goh, Brendon, Lord, Anton R, Travis, Jye A, Dowell, Floyd E, Birrell, Geoffrey W, Chavchich, Marina
Published in PloS one (25.03.2024)
Published in PloS one (25.03.2024)
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Journal Article
Quantification of Tafenoquine and 5,6-Orthoquinone Tafenoquine by UHPLC-MS/MS in Blood, Plasma, and Urine, and Application to a Pharmacokinetic Study
Birrell, Geoffrey W, Van Breda, Karin, Barber, Bridget, Webster, Rebecca, McCarthy, James S, Shanks, G Dennis, Edstein, Michael D
Published in Molecules (Basel, Switzerland) (24.11.2022)
Published in Molecules (Basel, Switzerland) (24.11.2022)
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Journal Article
Susceptibility of Plasmodium falciparum to artemisinins and Plasmodium vivax to chloroquine in Phuoc Chien Commune, Ninh Thuan Province, south-central Vietnam
Phong, Nguyen Chinh, Chavchich, Marina, Quang, Huynh Hong, San, Nguyen Ngoc, Birrell, Geoffrey W, Chuang, Ilin, Martin, Nicholas J, Manh, Nguyen Duc, Edstein, Michael D
Published in Malaria journal (17.01.2019)
Published in Malaria journal (17.01.2019)
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Journal Article
Pharmacokinetics and Ex Vivo Antimalarial Activity of Artesunate-Azithromycin in Healthy Volunteers
Chinh, Nguyen Trong, Quang, Nguyen Ngoc, Anh, Chu Xuan, Thanh, Nguyen Xuan, Dai, Bui, Birrell, Geoffrey W, Chavchich, Marina, Edstein, Michael D
Published in Antimicrobial Agents and Chemotherapy (01.09.2011)
Published in Antimicrobial Agents and Chemotherapy (01.09.2011)
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Journal Article
Therapeutic efficacy of pyronaridine-artesunate (Pyramax) in treating Plasmodium vivax malaria in the central highlands of Vietnam
Manh, Nguyen Duc, Thanh, Nguyen Van, Quang, Huynh Hong, Van, Nguyen Thi Thanh, San, Nguyen Ngoc, Phong, Nguen Chinh, Birrell, Geoffrey W., Edgel, Kimberly A., Martin, Nicholas J., Edstein, Michael D., Chavchich, Marina
Published in Antimicrobial agents and chemotherapy (04.09.2024)
Published in Antimicrobial agents and chemotherapy (04.09.2024)
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Journal Article
Characterizing the Blood-Stage Antimalarial Activity of Tafenoquine in Healthy Volunteers Experimentally Infected With Plasmodium falciparum
Barber, Bridget E, Abd-Rahman, Azrin N, Webster, Rebecca, Potter, Adam J, Llewellyn, Stacey, Marquart, Louise, Sahai, Nischal, Leelasena, Indika, Birrell, Geoffrey W, Edstein, Michael D, Shanks, G Dennis, Wesche, David, Moehrle, Joerg J, McCarthy, James S
Published in Clinical infectious diseases (08.06.2023)
Published in Clinical infectious diseases (08.06.2023)
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Journal Article
Multi-omic Characterization of the Mode of Action of a Potent New Antimalarial Compound, JPC-3210, Against Plasmodium falciparum
Birrell, Geoffrey W., Challis, Matthew P., De Paoli, Amanda, Anderson, Dovile, Devine, Shane M., Heffernan, Gavin D., Jacobus, David P., Edstein, Michael D., Siddiqui, Ghizal, Creek, Darren J.
Published in Molecular & cellular proteomics (01.02.2020)
Published in Molecular & cellular proteomics (01.02.2020)
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Journal Article
The Effect of Regularly Dosed Acetaminophen vs No Acetaminophen on Renal Function in Plasmodium knowlesi Malaria (PACKNOW): A Randomized, Controlled Trial
Cooper, Daniel J, Grigg, Matthew J, Plewes, Katherine, Rajahram, Giri S, Piera, Kim A, William, Timothy, Menon, Jayaram, Koleth, Glenn, Edstein, Michael D, Birrell, Geoffrey W, Wattanakul, Thanaporn, Tarning, Joel, Patel, Aatish, Wen Yeo, Tsin, Dondorp, Arjen M, Anstey, Nicholas M, Barber, Bridget E
Published in Clinical infectious diseases (12.10.2022)
Published in Clinical infectious diseases (12.10.2022)
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Journal Article
Pyronaridine-Artesunate (Pyramax) for Treatment of Artemisinin- and Piperaquine-Resistant Plasmodium falciparum in the Central Highlands of Vietnam
Manh, Nguyen Duc, Thanh, Nguyen Van, Quang, Huynh Hong, Van, Nguyen Thi Thanh, San, Nguyen Ngoc, Phong, Nguyen Chinh, Birrell, Geoffrey W, Edstein, Michael D, Edgel, Kimberly A, Martin, Nicholas J, Chavchich, Marina
Published in Antimicrobial agents and chemotherapy (17.11.2021)
Published in Antimicrobial agents and chemotherapy (17.11.2021)
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Journal Article
Transmission Blocking Activity of Low-dose Tafenoquine in Healthy Volunteers Experimentally Infected With Plasmodium falciparum
Webster, Rebecca, Mitchell, Hayley, Peters, Jenny M, Heunis, Juanita, O'Neill, Brighid, Gower, Jeremy, Lynch, Sean, Jennings, Helen, Amante, Fiona H, Llewellyn, Stacey, Marquart, Louise, Potter, Adam J, Birrell, Geoffrey W, Edstein, Michael D, Shanks, G Dennis, McCarthy, James S, Barber, Bridget E
Published in Clinical infectious diseases (08.02.2023)
Published in Clinical infectious diseases (08.02.2023)
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Journal Article
Pharmacokinetics and Ex Vivo Antimalarial Activity of Artesunate-Amodiaquine plus Methylene Blue in Healthy Volunteers
Anh, Chu Xuan, Chavchich, Marina, Birrell, Geoffrey W, Van Breda, Karin, Travers, Thomas, Rowcliffe, Kerryn, Lord, Anton R, Shanks, G Dennis, Edstein, Michael D
Published in Antimicrobial agents and chemotherapy (21.02.2020)
Published in Antimicrobial agents and chemotherapy (21.02.2020)
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Journal Article
Development of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administration
Parkinson, Christopher J, Birrell, Geoffrey W, Chavchich, Marina, Mackenzie, Donna, Haynes, Richard K, de Kock, Carmen, Richardson, Des R, Edstein, Michael D
Published in Journal of antimicrobial chemotherapy (01.10.2019)
Published in Journal of antimicrobial chemotherapy (01.10.2019)
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Journal Article
In Vivo Efficacy and Pharmacokinetics of the 2-Aminomethylphenol Antimalarial JPC-3210 in the Aotus Monkey-Human Malaria Model
McCallum, Fiona J, Birrell, Geoffrey W, Chavchich, Marina, Harris, Ivor, Obaldia, 3rd, Nicanor, Van Breda, Karin, Heffernan, Gavin D, Jacobus, David P, Shanks, Dennis, Edstein, Michael D
Published in Antimicrobial agents and chemotherapy (21.02.2020)
Published in Antimicrobial agents and chemotherapy (21.02.2020)
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Journal Article
Dinuclear ruthenium(ii) antimicrobial agents that selectively target polysomes in vivo
Li, Fangfei, Harry, Elizabeth J, Bottomley, Amy L, Edstein, Michael D, Birrell, Geoffrey W, Woodward, Clifford E, Keene, F. Richard, Collins, J. Grant
Published in Chemical science (Cambridge) (01.01.2014)
Published in Chemical science (Cambridge) (01.01.2014)
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Journal Article
Comparison of the Pharmacokinetics and Ex Vivo Antimalarial Activities of Artesunate-Amodiaquine and Artemisinin-Piperaquine in Healthy Volunteers for Preselection Malaria Therapy
Quang, Nguyen Ngoc, Chavchich, Marina, Anh, Chu Xuan, Birrell, Geoffrey W, van Breda, Karin, Travers, Thomas, Rowcliffe, Kerryn, Edstein, Michael D
Published in The American journal of tropical medicine and hygiene (01.01.2018)
Published in The American journal of tropical medicine and hygiene (01.01.2018)
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Journal Article
Characterization of the Preclinical Pharmacology of the New 2-Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention
Birrell, Geoffrey W, Heffernan, Gavin D, Schiehser, Guy A, Anderson, John, Ager, Arba L, Morales, Pablo, MacKenzie, Donna, van Breda, Karin, Chavchich, Marina, Jacobus, Laura R, Shanks, G Dennis, Jacobus, David P, Edstein, Michael D
Published in Antimicrobial agents and chemotherapy (01.04.2018)
Published in Antimicrobial agents and chemotherapy (01.04.2018)
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Journal Article
Lead Selection of a New Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention
Chavchich, Marina, Birrell, Geoffrey W, Ager, Arba L, MacKenzie, Donna O, Heffernan, Gavin D, Schiehser, Guy A, Jacobus, Laura R, Shanks, G Dennis, Jacobus, David P, Edstein, Michael D
Published in Antimicrobial agents and chemotherapy (01.05.2016)
Published in Antimicrobial agents and chemotherapy (01.05.2016)
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Journal Article
JPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial activities against blood stages of Plasmodium
Birrell, Geoffrey W, Chavchich, Marina, Ager, Arba L, Shieh, Hong-Ming, Heffernan, Gavin D, Zhao, Wenyi, Krasucki, Peter E, Saionz, Kurt W, Terpinski, Jacek, Schiehser, Guy A, Jacobus, Laura R, Shanks, G Dennis, Jacobus, David P, Edstein, Michael D
Published in Antimicrobial agents and chemotherapy (01.01.2015)
Published in Antimicrobial agents and chemotherapy (01.01.2015)
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Journal Article
Mitochondrial dysfunction after aerobic exposure to the hypoxic cytotoxin tirapazamine
WOUTERS, Bradly G, DELAHOUSSAYE, Yvette M, EVANS, James W, BIRRELL, Geoffrey W, DORIE, Mary Jo, JINGLI WANG, MACDERMED, Dhara, CHIU, Roland K, BROWN, J. Martin
Published in Cancer research (Chicago, Ill.) (2001)
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Published in Cancer research (Chicago, Ill.) (2001)
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