Synthesis of site-specific antibody-drug conjugates using unnatural amino acids
Axup, Jun Y, Bajjuri, Krishna M, Ritland, Melissa, Hutchins, Benjamin M, Kim, Chan Hyuk, Kazane, Stephanie A, Halder, Rajkumar, Forsyth, Jane S, Santidrian, Antonio F, Stafin, Karin, Lu, Yingchun, Tran, Hon, Seller, Aaron J, Biroc, Sandra L, Szydlik, Aga, Pinkstaff, Jason K, Tian, Feng, Sinha, Subhash C, Felding-Habermann, Brunhilde, Smider, Vaughn V, Schultz, Peter G
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2012)
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Journal Article
A general approach to site-specific antibody drug conjugates
Tian, Feng, Lu, Yingchun, Manibusan, Anthony, Sellers, Aaron, Tran, Hon, Sun, Ying, Phuong, Trung, Barnett, Richard, Hehli, Brad, Song, Frank, DeGuzman, Michael J., Ensari, Semsi, Pinkstaff, Jason K., Sullivan, Lorraine M., Biroc, Sandra L., Ho Cho, Schultz, Peter G., DiJoseph, John, Dougher, Maureen, Ma, Dangshe, Dushin, Russell, Leal, Mauricio, Tchistiakova, Lioudmila, Feyfant, Eric, Gerber, Hans-Peter, Sapra, Puja
Published in Proceedings of the National Academy of Sciences - PNAS (04.02.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (04.02.2014)
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Journal Article
Bispecific small molecule–antibody conjugate targeting prostate cancer
Kim, Chan Hyuk, Axup, Jun Y., Lawson, Brian R., Yun, Hwayoung, Tardif, Virginie, Choi, Sei Hyun, Zhou, Quan, Dubrovska, Anna, Biroc, Sandra L., Marsden, Robin, Pinstaff, Jason, Smider, Vaughn V., Schultz, Peter G.
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2013)
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Journal Article
The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models
Ying, Han, Biroc, Sandra L, Li, Wei-Wei, Alicke, Bruno, Xuan, Jian-Ai, Pagila, Rene, Ohashi, Yasuhiro, Okada, Toshiya, Kamata, Yoichi, Dinter, Harald
Published in Molecular cancer therapeutics (01.09.2006)
Published in Molecular cancer therapeutics (01.09.2006)
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Journal Article
Remodeling of the Mammary Microenvironment after Lactation Promotes Breast Tumor Cell Metastasis
McDaniel, Shauntae M., Rumer, Kristen K., Biroc, Sandra L., Metz, Richard P., Singh, Meenakshi, Porter, Weston, Schedin, Pepper
Published in The American journal of pathology (01.02.2006)
Published in The American journal of pathology (01.02.2006)
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Journal Article
Novel Small Molecule Inhibitors of 3-Phosphoinositide-dependent Kinase-1
Feldman, Richard I., Wu, James M., Polokoff, Mark A., Kochanny, Monica J., Dinter, Harald, Zhu, Daguang, Biroc, Sandra L., Alicke, Bruno, Bryant, Judi, Yuan, Shendong, Buckman, Brad O., Lentz, Dao, Ferrer, Mike, Whitlow, Marc, Adler, Marc, Finster, Silke, Chang, Zheng, Arnaiz, Damian O.
Published in The Journal of biological chemistry (20.05.2005)
Published in The Journal of biological chemistry (20.05.2005)
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Journal Article
Recruiting Cytotoxic T Cells to Folate-Receptor-Positive Cancer Cells
Kularatne, Sumith A., Deshmukh, Vishal, Gymnopoulos, Marco, Biroc, Sandra L., Xia, Jinming, Srinagesh, Shailaja, Sun, Ying, Zou, Ning, Shimazu, Mark, Pinkstaff, Jason, Ensari, Semsi, Knudsen, Nick, Manibusan, Anthony, Axup, Jun Y., Kim, Chan Hyuk, Smider, Vaughn V., Javahishvili, Tsotne, Schultz, Peter G.
Published in Angewandte Chemie (International ed.) (11.11.2013)
Published in Angewandte Chemie (International ed.) (11.11.2013)
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In Vivo Efficacy Study Showing Comparative Advantage of Bacterial Infection Prevention with Zip-type Skin Closure Device vs. Subcuticular Sutures
Safa, Bauback, Belson, Amir, Meschter, Carol, Kelley, Michelle, Stewart, Daren, Ichiryu, Kei, Biroc, Sandra, Storne, Eric
Published in Curēus (Palo Alto, CA) (04.08.2018)
Published in Curēus (Palo Alto, CA) (04.08.2018)
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Journal Article
Interferon receptor expression regulates the antiproliferative effects of interferons on cancer cells and solid tumors
Wagner, T. Charis, Velichko, Sharlene, Chesney, Steven K., Biroc, Sandra, Harde, Dean, Vogel, David, Croze, Ed
Published in International journal of cancer (10.08.2004)
Published in International journal of cancer (10.08.2004)
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Journal Article
Potent Triazolothione Inhibitor of Heat-Shock Protein-90
Feldman, Richard I, Mintzer, Bob, Zhu, Daguang, Wu, James M, Biroc, Sandra L, Yuan, Shendong, Emayan, Kumar, Chang, Zheng, Chen, Deborah, Arnaiz, Damian O, Bryant, Judi, Ge, Xue Snow, Whitlow, Marc, Adler, Marc, Polokoff, Mark A, Li, Wei-Wei, Ferrer, Mike, Sato, Takashi, Gu, Jian-Ming, Shen, Jun, Tseng, Jih-Lie, Dinter, Harald, Buckman, Brad
Published in Chemical biology & drug design (01.07.2009)
Published in Chemical biology & drug design (01.07.2009)
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Journal Article
Identification of a novel prostate tumor target, Mindin/RG-1, for antibody-based radiotherapy of prostate cancer
PARRY, Renate, SCHNEIDER, Doug, BIROC, Sandra, KRETSCHMER, Peter J, HALKS-MILLER, Meredith, KLOCKER, Helmut, YING ZHU, LARSEN, Brent, COBB, Ronald R, BRINGMANN, Peter, ROTH, Georg, LEWIS, Jason S, HUDSON, Debra, DINTER, Harald, PARRY, Gordon, PARKES, Debbie, XUAN, Jian-Ai, NEWTON, Alicia, TOY, Pam, LIN, Rick, HARKINS, Rick, ALICKE, Bruno
Published in Cancer research (Chicago, Ill.) (15.09.2005)
Published in Cancer research (Chicago, Ill.) (15.09.2005)
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Journal Article
Anti-EphA2 Antibodies Decrease EphA2 Protein Levels in Murine CT26 Colorectal and Human MDA-231 Breast Tumors But Do Not Inhibit Tumor Growth
Kiewlich, David, Zhang, Jianhuan, Gross, Cynthia, Xia, Wei, Larsen, Brent, Cobb, Ronald R., Biroc, Sandra, Gu, Jian-Ming, Sato, Takashi, Light, David R., Heitner, Tara, Willuda, Joerg, Vogel, David, Monteclaro, Felipe, Citkowicz, Andrzej, Roffler, Steve R., Zajchowski, Deborah A.
Published in Neoplasia (New York, N.Y.) (01.01.2006)
Published in Neoplasia (New York, N.Y.) (01.01.2006)
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Journal Article
Targeting tomoregulin for radioimmunotherapy of prostate cancer
ZHAO, Xiao-Yan, SCHNEIDER, Doug, MÜLLER-TIEMANN, Beate, PARRY, Gordon, DINTER, Harald, BIROC, Sandra L, PARRY, Renate, ALICKE, Bruno, TOY, Pamela, XUAN, Jian-Ai, SAKAMOTO, Choitsu, WADA, Ken, SCHULZE, Michael
Published in Cancer research (Chicago, Ill.) (01.04.2005)
Published in Cancer research (Chicago, Ill.) (01.04.2005)
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Journal Article
ARX788, a Site-specific Anti-HER2 Antibody–Drug Conjugate, Demonstrates Potent and Selective Activity in HER2-low and T-DM1–resistant Breast and Gastric Cancers
Skidmore, Lillian, Sakamuri, Sukumar, Knudsen, Nick A., Hewet, Amha Gebre, Milutinovic, Snezana, Barkho, Wisam, Biroc, Sandra Lyn, Kirtley, Jessica, Marsden, Robin, Storey, Kristine, Lopez, Ianina, Yu, Wayne, Fang, Shiao-Yan, Yao, Sulan, Gu, Yi, Tian, Feng
Published in Molecular cancer therapeutics (01.09.2020)
Published in Molecular cancer therapeutics (01.09.2020)
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Journal Article
Anti‐tumor efficacy of the nucleoside analog 1‐(2‐deoxy‐2‐fluoro‐4‐thio‐β‐D‐arabinofuranosyl) cytosine (4′‐thio‐FAC) in human pancreatic and ovarian tumor xenograft models
Zajchowski, Deborah A., Biroc, Sandra L., Liu, Hsaio‐Lai, Chesney, Steven K., Hoffmann, Jens, Bauman, John, Kirkland, Thomas, Subramanyam, Babu, Shen, Jun, Ho, Elena, Tseng, Jih‐Lie, Dinter, Harald
Published in International journal of cancer (10.05.2005)
Published in International journal of cancer (10.05.2005)
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Journal Article
Abstract 639: Site specific conjugation of ARX-788, an antibody drug conjugate (ADC) targeting HER2, generates a potent and stable targeted therapeutic for multiple cancers
Humphreys, Robin C., Kirtely, Jessica, Hewit, Amha, Biroc, Sandra, Knudsen, Nick, Skidmore, Lillian, Wahl, Alan
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
CD70 ANTI-CD70 ANTIBODY DRUG CONJUGATES
BRESSON DAMIEN, BIROC SANDRA, BARNETT RICHARD S, BUSS TIMOTHY, SUN YING, HEWET AMHA, PINKSTAFF JASON K, KNUDSEN NICK, SRINAGESH SHAILAJA, JAVAHISHVILI TSOTNE
Year of Publication 07.12.2021
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Year of Publication 07.12.2021
Patent
Human Cathepsin O2, a Matrix Protein-degrading Cysteine Protease Expressed in Osteoclasts
Brömme, Dieter, Okamoto, Kathleen, Wang, Bruce B., Biroc, Sandra
Published in The Journal of biological chemistry (01.01.1996)
Published in The Journal of biological chemistry (01.01.1996)
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Journal Article
Abstract 668: Folate conjugated site-specifically to anti-human-CD3-Fab is efficacious in mouse models of ovarian cancer
Biroc, Sandra L., Gymnopoulos, Marco, Srinagesh, Shailaja, Hayes, Brad, Knudsen, Nick, Manibusan, Anthony, Pinkstaff, Jason, Buss, Tim, Cox, Kari, Marsden, Robin, Skidmore, Lillian, Xia, Jinming, Sun, Ying, Zou, Ning, Javahishvili, Tsotne
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Human cathepsin O2, a matrix protein-degrading cysteine protease expressed in osteoclasts. Functional expression of human cathepsin O2 in Spodoptera frugiperda and characterization of the enzyme
Brömme, D, Okamoto, K, Wang, B B, Biroc, S
Published in The Journal of biological chemistry (26.01.1996)
Published in The Journal of biological chemistry (26.01.1996)
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