The SARS-CoV-2 main protease as drug target
Ullrich, Sven, Nitsche, Christoph
Published in Bioorganic & medicinal chemistry letters (01.09.2020)
Published in Bioorganic & medicinal chemistry letters (01.09.2020)
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Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir
Ullrich, Sven, Ekanayake, Kasuni B., Otting, Gottfried, Nitsche, Christoph
Published in Bioorganic & medicinal chemistry letters (15.04.2022)
Published in Bioorganic & medicinal chemistry letters (15.04.2022)
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The use of spirocyclic scaffolds in drug discovery
Zheng, Yajun, Tice, Colin M., Singh, Suresh B.
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
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Journal Article
Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead
Martino, Emanuela, Casamassima, Giuseppe, Castiglione, Sonia, Cellupica, Edoardo, Pantalone, Serena, Papagni, Francesca, Rui, Marta, Siciliano, Angela Marika, Collina, Simona
Published in Bioorganic & medicinal chemistry letters (15.09.2018)
Published in Bioorganic & medicinal chemistry letters (15.09.2018)
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N-Acylhydrazones as drugs
Thota, Sreekanth, Rodrigues, Daniel A., Pinheiro, Pedro de Sena Murteira, Lima, Lídia M., Fraga, Carlos A.M., Barreiro, Eliezer J.
Published in Bioorganic & medicinal chemistry letters (15.09.2018)
Published in Bioorganic & medicinal chemistry letters (15.09.2018)
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Journal Article
The long story of camptothecin: From traditional medicine to drugs
Martino, Emanuela, Della Volpe, Serena, Terribile, Elisa, Benetti, Emanuele, Sakaj, Mirena, Centamore, Adriana, Sala, Andrea, Collina, Simona
Published in Bioorganic & medicinal chemistry letters (15.02.2017)
Published in Bioorganic & medicinal chemistry letters (15.02.2017)
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Journal Article
New approaches for the treatment of Alzheimer’s disease
Fish, Paul V., Steadman, David, Bayle, Elliott D., Whiting, Paul
Published in Bioorganic & medicinal chemistry letters (15.01.2019)
Published in Bioorganic & medicinal chemistry letters (15.01.2019)
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Structural hybridization as a facile approach to new drug candidates
Sampath Kumar, Halmuthur M., Herrmann, Lars, Tsogoeva, Svetlana B.
Published in Bioorganic & medicinal chemistry letters (01.12.2020)
Published in Bioorganic & medicinal chemistry letters (01.12.2020)
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Discovery of a novel series of substituted quinolines acting as anticancer agents and selective EGFR blocker: Molecular docking study
Kumar, C.B. Pradeep, Raghu, M.S., Prathibha, B.S., Prashanth, M.K., Kanthimathi, G., Kumar, K. Yogesh, Parashuram, L., Alharthi, Fahad A.
Published in Bioorganic & medicinal chemistry letters (15.07.2021)
Published in Bioorganic & medicinal chemistry letters (15.07.2021)
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Development of the first small molecule histone deacetylase 6 (HDAC6) degraders
Yang, Ka, Song, Yanling, Xie, Haibo, Wu, Hao, Wu, Yi-Ting, Leisten, Eric D., Tang, Weiping
Published in Bioorganic & medicinal chemistry letters (01.08.2018)
Published in Bioorganic & medicinal chemistry letters (01.08.2018)
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Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum—The η-carbonic anhydrases
Del Prete, Sonia, Vullo, Daniela, Fisher, Gillian M., Andrews, Katherine T., Poulsen, Sally-Ann, Capasso, Clemente, Supuran, Claudiu T.
Published in Bioorganic & medicinal chemistry letters (15.09.2014)
Published in Bioorganic & medicinal chemistry letters (15.09.2014)
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Journal Article
Selective degradation of CDK6 by a palbociclib based PROTAC
Rana, Sandeep, Bendjennat, Mourad, Kour, Smit, King, Hannah M., Kizhake, Smitha, Zahid, Muhammad, Natarajan, Amarnath
Published in Bioorganic & medicinal chemistry letters (01.06.2019)
Published in Bioorganic & medicinal chemistry letters (01.06.2019)
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Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation
Furet, Pascal, Guagnano, Vito, Fairhurst, Robin A., Imbach-Weese, Patricia, Bruce, Ian, Knapp, Mark, Fritsch, Christine, Blasco, Francesca, Blanz, Joachim, Aichholz, Reiner, Hamon, Jacques, Fabbro, Doriano, Caravatti, Giorgio
Published in Bioorganic & medicinal chemistry letters (01.07.2013)
Published in Bioorganic & medicinal chemistry letters (01.07.2013)
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