Differential stability of cell-free circulating microRNAs: implications for their utilization as biomarkers
Köberle, Verena, Pleli, Thomas, Schmithals, Christian, Augusto Alonso, Eduardo, Haupenthal, Jörg, Bönig, Halvard, Peveling-Oberhag, Jan, Biondi, Ricardo M, Zeuzem, Stefan, Kronenberger, Bernd, Waidmann, Oliver, Piiper, Albrecht
Published in PloS one (20.09.2013)
Published in PloS one (20.09.2013)
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Journal Article
AGC protein kinases: From structural mechanism of regulation to allosteric drug development for the treatment of human diseases
Arencibia, José M., Pastor-Flores, Daniel, Bauer, Angelika F., Schulze, Jörg O., Biondi, Ricardo M.
Published in Biochimica et biophysica acta (01.07.2013)
Published in Biochimica et biophysica acta (01.07.2013)
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Journal Article
Predicting protein targets for drug-like compounds using transcriptomics
Pabon, Nicolas A, Xia, Yan, Estabrooks, Samuel K, Ye, Zhaofeng, Herbrand, Amanda K, Süß, Evelyn, Biondi, Ricardo M, Assimon, Victoria A, Gestwicki, Jason E, Brodsky, Jeffrey L, Camacho, Carlos J, Bar-Joseph, Ziv
Published in PLoS computational biology (01.12.2018)
Published in PLoS computational biology (01.12.2018)
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Journal Article
Alternative AKT2 splicing produces protein lacking the hydrophobic motif regulatory region
Plotz, Guido, Lopez-Garcia, Laura A, Brieger, Angela, Zeuzem, Stefan, Biondi, Ricardo M
Published in PloS one (30.11.2020)
Published in PloS one (30.11.2020)
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Journal Article
Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase
Schulze, Jörg O., Saladino, Giorgio, Busschots, Katrien, Neimanis, Sonja, Süß, Evelyn, Odadzic, Dalibor, Zeuzem, Stefan, Hindie, Valerie, Herbrand, Amanda K., Lisa, María-Natalia, Alzari, Pedro M., Gervasio, Francesco L., Biondi, Ricardo M.
Published in Cell chemical biology (20.10.2016)
Published in Cell chemical biology (20.10.2016)
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Journal Article
Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway
González, Lorena, Díaz, Lucía, Pous, Joan, Baginski, Blazej, Duran-Corbera, Anna, Scarpa, Margherita, Brun-Heath, Isabelle, Igea, Ana, Martin-Malpartida, Pau, Ruiz, Lidia, Pallara, Chiara, Esguerra, Mauricio, Colizzi, Francesco, Mayor-Ruiz, Cristina, Biondi, Ricardo M, Soliva, Robert, Macias, Maria J, Orozco, Modesto, Nebreda, Angel R
Published in Nature communications (12.06.2023)
Published in Nature communications (12.06.2023)
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Journal Article
Activation of Adenylyl Cyclase Causes Stimulation of Adenosine Receptors
Pleli, Thomas, Mondorf, Antonia, Ferreiros, Nerea, Thomas, Dominique, Dvorak, Karel, Biondi, Ricardo M., Heringdorf, Dagmar Meyer zu, Zeuzem, Stefan, Geisslinger, Gerd, Zimmermann, Herbert, Waidmann, Oliver, Piiper, Albrecht
Published in Cellular physiology and biochemistry (01.04.2018)
Published in Cellular physiology and biochemistry (01.04.2018)
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Journal Article
Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis
Lisa, María-Natalia, Gil, Magdalena, André-Leroux, Gwénaëlle, Barilone, Nathalie, Durán, Rosario, Biondi, Ricardo M., Alzari, Pedro M.
Published in Structure (London) (02.06.2015)
Published in Structure (London) (02.06.2015)
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Journal Article
InterAKTions with FKBPs--mutational and pharmacological exploration
Fabian, Anne-Katrin, März, Andreas, Neimanis, Sonja, Biondi, Ricardo M, Kozany, Christian, Hausch, Felix
Published in PloS one (28.02.2013)
Published in PloS one (28.02.2013)
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Journal Article
A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG
Lisa, María-Natalia, Sogues, Adrià, Barilone, Nathalie, Baumgart, Meike, Gil, Magdalena, Graña, Martín, Durán, Rosario, Biondi, Ricardo M, Bellinzoni, Marco, Bott, Michael, Alzari, Pedro M
Published in mBio (26.10.2021)
Published in mBio (26.10.2021)
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Journal Article
Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1
Biondi, Ricardo M, Hindie, Valerie, Stroba, Adriana, Zhang, Hua, Lopez-Garcia, Laura A, Idrissova, Leila, Zeuzem, Stefan, Hirschberg, Daniel, Schaeffer, Francis, Jørgensen, Thomas J D, Engel, Matthias, Alzari, Pedro M
Published in Nature chemical biology (01.10.2009)
Published in Nature chemical biology (01.10.2009)
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Journal Article
2‑(3-Oxo-1,3-diphenylpropyl)malonic Acids as Potent Allosteric Ligands of the PIF Pocket of Phosphoinositide-Dependent Kinase-1: Development and Prodrug Concept
Wilhelm, Adriana, Lopez-Garcia, Laura A, Busschots, Katrien, Fröhner, Wolfgang, Maurer, Frauke, Boettcher, Stefan, Zhang, Hua, Schulze, Jörg O, Biondi, Ricardo M, Engel, Matthias
Published in Journal of medicinal chemistry (26.11.2012)
Published in Journal of medicinal chemistry (26.11.2012)
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Journal Article
Identification of Key Phospholipids That Bind and Activate Atypical PKCs
Velnati, Suresh, Centonze, Sara, Girivetto, Federico, Capello, Daniela, Biondi, Ricardo M, Bertoni, Alessandra, Cantello, Roberto, Ragnoli, Beatrice, Malerba, Mario, Graziani, Andrea, Baldanzi, Gianluca
Published in Biomedicines (06.01.2021)
Published in Biomedicines (06.01.2021)
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Journal Article
Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation
Hauge, Camilla, Antal, Torben L, Hirschberg, Daniel, Doehn, Ulrik, Thorup, Katrine, Idrissova, Leila, Hansen, Klaus, Jensen, Ole N, Jørgensen, Thomas J, Biondi, Ricardo M, Frödin, Morten
Published in The EMBO journal (02.05.2007)
Published in The EMBO journal (02.05.2007)
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Journal Article
Renaissance of Allostery to Disrupt Protein Kinase Interactions
Leroux, Alejandro E., Biondi, Ricardo M.
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.01.2020)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.01.2020)
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Journal Article
AGC kinases, mechanisms of regulation and innovative drug development
Leroux, Alejandro E, Schulze, Jörg, Biondi, Ricardo M
Published in Seminars in cancer biology (01.02.2018)
Published in Seminars in cancer biology (01.02.2018)
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Journal Article
Regulation of the Interaction between Protein Kinase C-related Protein Kinase 2 (PRK2) and Its Upstream Kinase, 3-Phosphoinositide-dependent Protein Kinase 1 (PDK1)
Dettori, Rosalia, Sonzogni, Silvina, Meyer, Lucas, Lopez-Garcia, Laura A., Morrice, Nick A., Zeuzem, Stefan, Engel, Matthias, Piiper, Albrecht, Neimanis, Sonja, Frödin, Morten, Biondi, Ricardo M.
Published in The Journal of biological chemistry (30.10.2009)
Published in The Journal of biological chemistry (30.10.2009)
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Journal Article
Inhibition of the Equilibrative Nucleoside Transporter 1 and Activation of A2A Adenosine Receptors by 8-(4-Chlorophenylthio)-modified cAMP Analogs and Their Hydrolytic Products
Waidmann, Oliver, Pleli, Thomas, Dvorak, Karel, Baehr, Christina, Mondorf, Ulrich, Plotz, Guido, Biondi, Ricardo M., Zeuzem, Stefan, Piiper, Albrecht
Published in The Journal of biological chemistry (20.11.2009)
Published in The Journal of biological chemistry (20.11.2009)
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Journal Article
Synergistic Allostery in Multiligand-Protein Interactions
Ghode, Abhijeet, Gross, Lissy Z.F., Tee, Wei-Ven, Guarnera, Enrico, Berezovsky, Igor N., Biondi, Ricardo M., Anand, Ganesh S.
Published in Biophysical journal (03.11.2020)
Published in Biophysical journal (03.11.2020)
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