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Safety, tolerability, pharmacodynamics and pharmacokinetics of DWP14012, a novel potassium‐competitive acid blocker, in healthy male subjects
Sunwoo, J., Oh, J., Moon, S. J., Ji, S. C., Lee, S. H., Yu, K.‐S., Kim, H. S., Lee, A., Jang, I.‐J.
Published in Alimentary pharmacology & therapeutics (01.07.2018)
Published in Alimentary pharmacology & therapeutics (01.07.2018)
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Within-Subject Comparison of [11C]-( + )-PHNO and [11C]raclopride Sensitivity to Acute Amphetamine Challenge in Healthy Humans
Shotbolt, Paul, Tziortzi, Andri C, Searle, Graham E, Colasanti, Alessandro, van der Aart, Jasper, Abanades, Sergio, Plisson, Christophe, Miller, Sam R, Huiban, Mickael, Beaver, John D, Gunn, Roger N, Laruelle, Marc, Rabiner, Eugenii A
Published in Journal of cerebral blood flow and metabolism (01.01.2012)
Published in Journal of cerebral blood flow and metabolism (01.01.2012)
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Mixed-Affinity Binding in Humans with 18-kDa Translocator Protein Ligands
Owen, David R.J., Gunn, Roger N., Rabiner, Eugenii A., Bennacef, Idriss, Fujita, Masahiro, Kreisl, William C., Innis, Robert B., Pike, Victor W., Reynolds, Richard, Matthews, Paul M., Parker, Christine A.
Published in Journal of Nuclear Medicine (01.01.2011)
Published in Journal of Nuclear Medicine (01.01.2011)
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pH-dependent binding of ATP aptamer to the target and competition strands: Fluorescent melting curve fitting study
Gabrusenok, P.V., Ramazanov, R.R., Kasyanenko, N.A., Lantushenko, A.O., Sokolov, P.A.
Published in Biochimica et biophysica acta. General subjects (01.11.2024)
Published in Biochimica et biophysica acta. General subjects (01.11.2024)
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Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue
Ni, R., Gillberg, P.-G., Bergfors, A., Marutle, A., Nordberg, A.
Published in Brain (London, England : 1878) (01.07.2013)
Published in Brain (London, England : 1878) (01.07.2013)
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Investigation of the Impact of Substrate Selection on In Vitro Organic Anion Transporting Polypeptide 1B1 Inhibition Profiles for the Prediction of Drug-Drug Interactions
Izumi, Saki, Nozaki, Yoshitane, Maeda, Kazuya, Komori, Takafumi, Takenaka, Osamu, Kusuhara, Hiroyuki, Sugiyama, Yuichi
Published in Drug metabolism and disposition (01.02.2015)
Published in Drug metabolism and disposition (01.02.2015)
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An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28
Owen, David R, Yeo, Astrid J, Gunn, Roger N, Song, Kijoung, Wadsworth, Graham, Lewis, Andrew, Rhodes, Chris, Pulford, David J, Bennacef, Idriss, Parker, Christine A, StJean, Pamela L, Cardon, Lon R, Mooser, Vincent E, Matthews, Paul M, Rabiner, Eugenii A, Rubio, Justin P
Published in Journal of cerebral blood flow and metabolism (01.01.2012)
Published in Journal of cerebral blood flow and metabolism (01.01.2012)
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Imaging Dopamine D3 Receptors in the Human Brain with Positron Emission Tomography, [11 C]PHNO, and a Selective D3 Receptor Antagonist
Searle, Graham, Beaver, John D, Comley, Robert A, Bani, Massimo, Tziortzi, Andri, Slifstein, Mark, Mugnaini, Manolo, Griffante, Cristiana, Wilson, Alan A, Merlo-Pich, Emilio, Houle, Sylvain, Gunn, Roger, Rabiner, Eugenii A, Laruelle, Marc
Published in Biological psychiatry (1969) (15.08.2010)
Published in Biological psychiatry (1969) (15.08.2010)
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La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region
Philippe, Lucas, Vasseur, Jean-Jacques, Debart, Françoise, Thoreen, Carson C
Published in Nucleic acids research (16.02.2018)
Published in Nucleic acids research (16.02.2018)
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Switching brain serotonin with oxytocin
Mottolese, Raphaelle, Redouté, Jérôme, Costes, Nicolas, Le Bars, Didier, Sirigu, Angela
Published in Proceedings of the National Academy of Sciences - PNAS (10.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (10.06.2014)
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Blockade of [11C](+)-PHNO binding in human subjects by the dopamine D3 receptor antagonist ABT-925
Graff-Guerrero, Ariel, Redden, Laura, Abi-Saab, Walid, Katz, David A., Houle, Sylvain, Barsoum, Penny, Bhathena, Anahita, Palaparthy, Ramesh, Saltarelli, Mario D., Kapur, Shitij
Published in The international journal of neuropsychopharmacology (01.04.2010)
Published in The international journal of neuropsychopharmacology (01.04.2010)
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Evidence for natural antisense transcript-mediated inhibition of microRNA function
Faghihi, Mohammad Ali, Zhang, Ming, Huang, Jia, Modarresi, Farzaneh, Van der Brug, Marcel P, Nalls, Michael A, Cookson, Mark R, St-Laurent, Georges, Wahlestedt, Claes
Published in Genome biology (27.05.2010)
Published in Genome biology (27.05.2010)
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Increased Occupancy of Dopamine Receptors in Human Striatum during Cue-Elicited Cocaine Craving
Wong, Dean F, Kuwabara, Hiroto, Schretlen, David J, Bonson, Katherine R, Zhou, Yun, Nandi, Ayon, Brašić, James R, Kimes, Alane S, Maris, Marika A, Kumar, Anil, Contoreggi, Carlo, Links, Jonathan, Ernst, Monique, Rousset, Olivier, Zukin, Stephen, Grace, Anthony A, Rohde, Charles, Jasinski, Donald R, Gjedde, Albert, London, Edythe D
Published in Neuropsychopharmacology (New York, N.Y.) (01.12.2006)
Published in Neuropsychopharmacology (New York, N.Y.) (01.12.2006)
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Low Density Lipoprotein Binds to Proprotein Convertase Subtilisin/Kexin Type-9 (PCSK9) in Human Plasma and Inhibits PCSK9-mediated Low Density Lipoprotein Receptor Degradation
Kosenko, Tanja, Golder, Mia, Leblond, Geoffrey, Weng, Willy, Lagace, Thomas A.
Published in The Journal of biological chemistry (22.03.2013)
Published in The Journal of biological chemistry (22.03.2013)
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Influence of Affinity and Antigen Internalization on the Uptake and Penetration of Anti-HER2 Antibodies in Solid Tumors
Rudnick, Stephen I., Lou, Jianlong, Shaller, Calvin C., Tang, Yong, Klein-Szanto, Andres J.P., Weiner, Louis M., Marks, James D., Adams, Gregory P.
Published in Cancer research (Chicago, Ill.) (15.03.2011)
Published in Cancer research (Chicago, Ill.) (15.03.2011)
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Glucagon-like Peptide 1 Conjugated to Recombinant Human Serum Albumin Variants with Modified Neonatal Fc Receptor Binding Properties. Impact on Molecular Structure and Half-Life
Bukrinski, Jens T, Sønderby, Pernille, Antunes, Filipa, Andersen, Birgitte, Schmidt, Esben G. W, Peters, Günther H. J, Harris, Pernille
Published in Biochemistry (Easton) (12.09.2017)
Published in Biochemistry (Easton) (12.09.2017)
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Dopamine D2 and D3 Receptor Occupancy in Normal Humans Treated with the Antipsychotic Drug Aripiprazole (OPC 14597): A Study Using Positron Emission Tomography and [11C]Raclopride
Yokoi, Fuji, Ph.D, M.D, Gründer, Gerhard, Biziere, Kathleen, Stephane, Massoud, Dogan, Ahmet S, Dannals, Robert F, Ravert, Hayden, Suri, Ajit, Bramer, Steven, Wong, Dean F
Published in Neuropsychopharmacology (New York, N.Y.) (01.08.2002)
Published in Neuropsychopharmacology (New York, N.Y.) (01.08.2002)
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Novel Functional Polymorphisms in the UGT1A7 and UGT1A9 Glucuronidating Enzymes in Caucasian and African-American Subjects and Their Impact on the Metabolism of 7-Ethyl-10-hydroxycamptothecin and Flavopiridol Anticancer Drugs
Villeneuve, Lyne, Girard, Hugo, Fortier, Louis-Charles, Gagné, Jean-Francois, Guillemette, Chantal
Published in The Journal of pharmacology and experimental therapeutics (01.10.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2003)
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