Cancer prevention and therapy through the modulation of the tumor microenvironment
Casey, Stephanie C, Amedei, Amedeo, Aquilano, Katia, Azmi, Asfar S, Benencia, Fabian, Bhakta, Dipita, Bilsland, Alan E, Boosani, Chandra S, Chen, Sophie, Ciriolo, Maria Rosa, Crawford, Sarah, Fujii, Hiromasa, Georgakilas, Alexandros G, Guha, Gunjan, Halicka, Dorota, Helferich, William G, Heneberg, Petr, Honoki, Kanya, Keith, W. Nicol, Kerkar, Sid P, Mohammed, Sulma I, Niccolai, Elena, Nowsheen, Somaira, Vasantha Rupasinghe, H.P, Samadi, Abbas, Singh, Neetu, Talib, Wamidh H, Venkateswaran, Vasundara, Whelan, Richard L, Yang, Xujuan, Felsher, Dean W
Published in Seminars in cancer biology (01.12.2015)
Published in Seminars in cancer biology (01.12.2015)
Get full text
Journal Article
Automated Generation of Novel Fragments Using Screening Data, a Dual SMILES Autoencoder, Transfer Learning and Syntax Correction
Bilsland, Alan E, McAulay, Kirsten, West, Ryan, Pugliese, Angelo, Bower, Justin
Published in Journal of chemical information and modeling (28.06.2021)
Published in Journal of chemical information and modeling (28.06.2021)
Get full text
Journal Article
A Novel Pyrazolopyrimidine Ligand of Human PGK1 and Stress Sensor DJ1 Modulates the Shelterin Complex and Telomere Length Regulation
Bilsland, Alan E., Liu, Yu, Turnbull, Andrew, Sumpton, David, Stevenson, Katrina, Cairney, Claire J., Boyd, Susan M., Roffey, Jon, Jenkinson, David, Keith, W. Nicol
Published in Neoplasia (New York, N.Y.) (01.09.2019)
Published in Neoplasia (New York, N.Y.) (01.09.2019)
Get full text
Journal Article
A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds
Cairney, Claire J, Godwin, Lauren S, Bilsland, Alan E, Burns, Sharon, Stevenson, Katrina H, McGarry, Lynn, Revie, John, Moore, Jon D, Wiggins, Ceri M, Collinson, Rebecca S, Mudd, Clare, Tsonou, Elpida, Sadaie, Mahito, Bennett, Dorothy C, Narita, Masashi, Torrance, Christopher J, Keith, W Nicol
Published in PLoS genetics (01.08.2017)
Published in PLoS genetics (01.08.2017)
Get full text
Journal Article
Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks
Bilsland, Alan E, Pugliese, Angelo, Liu, Yu, Revie, John, Burns, Sharon, McCormick, Carol, Cairney, Claire J, Bower, Justin, Drysdale, Martin, Narita, Masashi, Sadaie, Mahito, Keith, W. Nicol
Published in Neoplasia (New York, N.Y.) (01.09.2015)
Published in Neoplasia (New York, N.Y.) (01.09.2015)
Get full text
Journal Article
Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms
Bilsland, Alan E, Stevenson, Katrina, Liu, Yu, Hoare, Stacey, Cairney, Claire J, Roffey, Jon, Keith, W Nicol
Published in PLoS computational biology (01.02.2014)
Published in PLoS computational biology (01.02.2014)
Get full text
Journal Article
Modulation of telomerase promoter tumor selectivity in the context of oncolytic adenoviruses
BILSLAND, Alan E, MERRON, Andrew, VASSAUX, Georges, KEITH, W. Nicol
Published in Cancer research (Chicago, Ill.) (01.02.2007)
Published in Cancer research (Chicago, Ill.) (01.02.2007)
Get full text
Journal Article
Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase
BILSLAND, Alan E, ANDERSON, Claire J, FLETCHER-MONAGHAN, Aileen J, MCGREGOR, Fiona, EVANS, T. R, GANLY, Ian, KNOX, Richard J, PLUMB, Jane A, KEITH, W. Nicol
Published in Oncogene (23.01.2003)
Published in Oncogene (23.01.2003)
Get full text
Journal Article
Dynamic telomerase gene suppression via network effects of GSK3 inhibition
Bilsland, Alan E, Hoare, Stacey, Stevenson, Katrina, Plumb, Jane, Gomez-Roman, Natividad, Cairney, Claire, Burns, Sharon, Lafferty-Whyte, Kyle, Roffey, Jon, Hammonds, Tim, Keith, W Nicol
Published in PloS one (31.07.2009)
Published in PloS one (31.07.2009)
Get full text
Journal Article
Cancer cell senescence: a new frontier in drug development
Cairney, Claire J., Bilsland, Alan E., Evans, T.R. Jeffry, Roffey, Jon, Bennett, Dorothy C., Narita, Masashi, Torrance, Christopher J., Keith, W. Nicol
Published in Drug discovery today (01.03.2012)
Published in Drug discovery today (01.03.2012)
Get full text
Journal Article
Plasma N-acetyl-glucosaminidase in advanced gastro-intestinal adenocarcinoma correlates with age, stage and outcome
Hartmann, Daniel, von Figura, Guido, Song, Zhangfa, Harden, Sharon, Scott, Lucy C, Evans, T R Jeffry, Rudolph, Karl Lenhard, Bilsland, Alan E, Keith, W Nicol
Published in Future oncology (London, England) (01.01.2015)
Published in Future oncology (London, England) (01.01.2015)
Get full text
Journal Article
Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks12
Bilsland, Alan E., Pugliese, Angelo, Liu, Yu, Revie, John, Burns, Sharon, McCormick, Carol, Cairney, Claire J., Bower, Justin, Drysdale, Martin, Narita, Masashi, Sadaie, Mahito, Keith, W. Nicol
Published in Neoplasia (New York, N.Y.) (19.10.2015)
Published in Neoplasia (New York, N.Y.) (19.10.2015)
Get full text
Journal Article
Mathematical Model of a Telomerase Transcriptional Regulatory Network Developed by Cell-Based Screening: Analysis of Inhibitor Effects and Telomerase Expression Mechanisms: e1003448
Bilsland, Alan E, Stevenson, Katrina, Liu, Yu, Hoare, Stacey, Cairney, Claire J, Roffey, Jon, Keith, W Nicol
Published in PLoS computational biology (01.02.2014)
Published in PLoS computational biology (01.02.2014)
Get full text
Journal Article
Plasma
Hartmann, Daniel, von Figura, Guido, Song, Zhangfa, Harden, Sharon, Scott, Lucy C, Evans, TR Jeffry, Rudolph, Karl Lenhard, Bilsland, Alan E, Keith, W Nicol
Published in Future oncology (London, England) (01.01.2015)
Published in Future oncology (London, England) (01.01.2015)
Get full text
Journal Article