Imidazodipyridines via DMAP Catalyzed Domino N−H Carbonylation and 6π‐Electrocyclization: Synthetic Scope and Application
Zhang, Kena, El Bouakher, Abderrahman, Lévaique, Hélène, Bignon, Jérome, Retailleau, Pascal, Alami, Mouad, Hamze, Abdallah
Published in Advanced synthesis & catalysis (04.08.2020)
Published in Advanced synthesis & catalysis (04.08.2020)
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Journal Article
N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents
Khelifi, Ilhem, Naret, Timothée, Hamze, Abdallah, Bignon, Jérome, Levaique, Hélène, Garcia Alvarez, Maria Concepcion, Dubois, Joëlle, Provot, Olivier, Alami, Mouad
Published in European journal of medicinal chemistry (15.04.2019)
Published in European journal of medicinal chemistry (15.04.2019)
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Journal Article
Anacardic Acids from Knema hookeriana as Modulators of Bcl-xL/Bak and Mcl-1/Bid Interactions
Gény, Charlotte, Rivière, Gwladys, Bignon, Jérome, Birlirakis, Nicolas, Guittet, Eric, Awang, Khaljah, Litaudon, Marc, Roussi, Fanny, Dumontet, Vincent
Published in Journal of natural products (Washington, D.C.) (22.04.2016)
Published in Journal of natural products (Washington, D.C.) (22.04.2016)
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Journal Article
Anticancer properties of indole derivatives as IsoCombretastatin A-4 analogues
Pecnard, Shannon, Hamze, Abdallah, Bignon, Jérome, Prost, Bastien, Deroussent, Alain, Gallego-Yerga, Laura, Peláez, Rafael, Paik, Ji Yeon, Diederich, Marc, Alami, Mouad, Provot, Olivier
Published in European journal of medicinal chemistry (05.11.2021)
Published in European journal of medicinal chemistry (05.11.2021)
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Journal Article
Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors
Khelifi, Ilhem, Naret, Timothée, Renko, Dolor, Hamze, Abdallah, Bernadat, Guillaume, Bignon, Jérome, Lenoir, Christine, Dubois, Joëlle, Brion, Jean-Daniel, Provot, Olivier, Alami, Mouad
Published in European journal of medicinal chemistry (15.02.2017)
Published in European journal of medicinal chemistry (15.02.2017)
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Journal Article
Discovery of azaisoerianin derivatives as potential antitumors agents
Soussi, Mohamed Ali, Provot, Olivier, Bernadat, Guillaume, Bignon, Jerome, Wdzieczak-Bakala, Joanna, Desravines, Deborah, Dubois, Joelle, Brion, Jean-Daniel, Messaoudi, Samir, Alami, Mouad
Published in European journal of medicinal chemistry (06.05.2014)
Published in European journal of medicinal chemistry (06.05.2014)
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Journal Article
Pro-apoptotic carboxamide analogues of natural fislatifolic acid targeting Mcl-1 and Bcl-2
Gapil Tiamas, Shelly, Daressy, Florian, Abou Samra, Alma, Bignon, Jérome, Steinmetz, Vincent, Litaudon, Marc, Fourneau, Christophe, Hoong Leong, Kok, Ariffin, Azhar, Awang, Khalijah, Desrat, Sandy, Roussi, Fanny
Published in Bioorganic & medicinal chemistry letters (01.04.2020)
Published in Bioorganic & medicinal chemistry letters (01.04.2020)
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Journal Article
Synthesis and Anticancer Properties of Oxazepines Related to Azaisoerianin and IsoCoQuines
Khelifi, Ilhem, Pecnard, Shannon, Bernadat, Guillaume, Bignon, Jérome, Levaique, Hélène, Dubois, Joëlle, Provot, Olivier, Alami, Mouad
Published in ChemMedChem (19.08.2020)
Published in ChemMedChem (19.08.2020)
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Journal Article
IsoCombretaQuinazolines: Potent Cytotoxic Agents with Antitubulin Activity
Soussi, Mohamed Ali, Provot, Olivier, Bernadat, Guillaume, Bignon, Jérome, Desravines, Déborah, Dubois, Joëlle, Brion, Jean-Daniel, Messaoudi, Samir, Alami, Mouad
Published in ChemMedChem (01.08.2015)
Published in ChemMedChem (01.08.2015)
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Journal Article
Conformationnally restricted naphthalene derivatives type isocombretastatin A-4 and isoerianin analogues: Synthesis, cytotoxicity and antitubulin activity
Rasolofonjatovo, Evelia, Provot, Olivier, Hamze, Abdallah, Rodrigo, Jordi, Bignon, Jérome, Wdzieczak-Bakala, Joanna, Desravines, Déborah, Dubois, Joëlle, Brion, Jean-Daniel, Alami, Mouad
Published in European journal of medicinal chemistry (01.06.2012)
Published in European journal of medicinal chemistry (01.06.2012)
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Journal Article
Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation
Pecnard, Shannon, Provot, Olivier, Levaique, Hélène, Bignon, Jérome, Askenatzis, Laurie, Saller, Francois, Borgel, Delphine, Michallet, Sophie, Laisne, Marie-Catherine, Lafanechère, Laurence, Alami, Mouad, Hamze, Abdallah
Published in European journal of medicinal chemistry (01.01.2021)
Published in European journal of medicinal chemistry (01.01.2021)
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Journal Article
Nitric oxide activates an Nrf2/sulfiredoxin antioxidant pathway in macrophages
Abbas, Kahina, Breton, Jacques, Planson, Anne-Gaelle, Bouton, Cécile, Bignon, Jérome, Seguin, Cendrine, Riquier, Sylvie, Toledano, Michel B., Drapier, Jean-Claude
Published in Free radical biology & medicine (01.07.2011)
Published in Free radical biology & medicine (01.07.2011)
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Journal Article
Asymmetric Total Synthesis and Biological Evaluation of Proapoptotic Natural Myrcene‐Derived Cyclohexenyl Chalcones
Tiamas, Shelly Gapil, Audet, Florian, Samra, Alma Abou, Bignon, Jérome, Litaudon, Marc, Fourneau, Christophe, Ariffin, Azhar, Awang, Khalijah, Desrat, Sandy, Roussi, Fanny
Published in European journal of organic chemistry (15.11.2018)
Published in European journal of organic chemistry (15.11.2018)
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Journal Article
Regioselective hydrostannation of diarylalkynes directed by a labile ortho bromine atom: An easy access to stereodefined triarylolefins, hybrids of combretastatin A-4 and isocombretastatin A-4
Rasolofonjatovo, Evelia, Provot, Olivier, Hamze, Abdallah, Bignon, Jérome, Thoret, Sylviane, Brion, Jean-Daniel, Alami, Mouâd
Published in European journal of medicinal chemistry (01.09.2010)
Published in European journal of medicinal chemistry (01.09.2010)
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Journal Article
Design, synthesis and anticancer properties of 5-arylbenzoxepins as conformationally restricted isocombretastatin A-4 analogs
Rasolofonjatovo, Evelia, Provot, Olivier, Hamze, Abdallah, Rodrigo, Jordi, Bignon, Jerome, Wdzieczak-Bakala, Joanna, Lenoir, Christine, Desravines, Deborah, Dubois, Joelle, Brion, Jean-Daniel, Alami, Mouad
Published in European journal of medicinal chemistry (01.04.2013)
Published in European journal of medicinal chemistry (01.04.2013)
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Journal Article
Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A‑4
Lamaa, Diana, Lin, Hsin-Ping, Zig, Lena, Bauvais, Cyril, Bollot, Guillaume, Bignon, Jérôme, Levaique, Helene, Pamlard, Olivier, Dubois, Joelle, Ouaissi, Mehdi, Souce, Martin, Kasselouri, Athena, Saller, François, Borgel, Delphine, Jayat-Vignoles, Chantal, Al-Mouhammad, Hazar, Feuillard, Jean, Benihoud, Karim, Alami, Mouad, Hamze, Abdallah
Published in Journal of medicinal chemistry (09.08.2018)
Published in Journal of medicinal chemistry (09.08.2018)
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Journal Article
Inhibition of p53-Murine Double Minute 2 (MDM2) Interactions with 3,3′-Spirocyclopentene Oxindole Derivatives
Gicquel, Maxime, Gomez, Catherine, Garcia Alvarez, Maria Concepcion, Pamlard, Olivier, Guérineau, Vincent, Jacquet, Eric, Bignon, Jérôme, Voituriez, Arnaud, Marinetti, Angela
Published in Journal of medicinal chemistry (25.10.2018)
Published in Journal of medicinal chemistry (25.10.2018)
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Journal Article
Visualization of an Endogenous Mitochondrial Azoreductase Activity under Normoxic Conditions Using a Naphthalimide Azo-Based Fluorogenic Probe
Michel, Laurane, Auvray, Marie, Askenatzis, Laurie, Badet-Denisot, Marie-Ange, Bignon, Jérôme, Durand, Philippe, Mahuteau-Betzer, Florence, Chevalier, Arnaud
Published in Analytical chemistry (Washington) (30.01.2024)
Published in Analytical chemistry (Washington) (30.01.2024)
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