Expression and Localization of Rat Aldo-Keto Reductases and Induction of the 1B13 and 1D2 Isoforms by Phenolic Antioxidants
MACLEOD, A. Kenneth, KELLY, Vincent P, HIGGINS, Larry G, KELLEHER, Michael O, PRICE, Sally A, BIGLEY, Alison L, BETTON, Graham R, HAYES, John D
Published in Drug metabolism and disposition (01.02.2010)
Published in Drug metabolism and disposition (01.02.2010)
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Using Automated Image Analysis Algorithms to Distinguish Normal, Aberrant, and Degenerate Mitotic Figures Induced by Eg5 Inhibition
Bigley, Alison L, Klein, Stephanie K, Davies, Barry, Williams, Leigh, Rudmann, Daniel G
Published in Toxicologic pathology (01.07.2016)
Published in Toxicologic pathology (01.07.2016)
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ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration
WEDGE, Stephen R, OGILVIE, Donald J, GRAHAM, George A, HUGHES, Gareth D, THOMAS, Andrew P, STOKES, Elaine S. E, CURRY, Brenda, RICHMOND, Graham H. P, WADSWORTH, Peter F, BIGLEY, Alison L, HENNEQUIN, Laurent F, DUKES, Michael, KENDREW, Jane, CHESTER, Rosemary, JACKSON, Janet A, BOFFEY, Sarah J, VALENTINE, Paula J, CURWEN, Jon O, MUSGROVE, Helen L
Published in Cancer research (Chicago, Ill.) (15.08.2002)
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Published in Cancer research (Chicago, Ill.) (15.08.2002)
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Gammaherpesvirus infection modulates the temporal and spatial expression of SCGB1A1 (CCSP) and BPIFA1 (SPLUNC1) in the respiratory tract
Leeming, Gail H, Kipar, Anja, Hughes, David J, Bingle, Lynne, Bennett, Elaine, Moyo, Nathifa A, Tripp, Ralph A, Bigley, Alison L, Bingle, Colin D, Sample, Jeffery T, Stewart, James P
Published in Laboratory investigation (01.06.2015)
Published in Laboratory investigation (01.06.2015)
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Quantitative histopathological assessment of retardation of islets of langerhans degeneration in rosiglitazone-dosed obese ZDF rats using combined insulin and collagens (I and III) immunohistochemistry with automated image analysis and statistical modeling
Jones, Huw B, Bigley, Alison L, Pemberton, John, Randall, Kevin J
Published in Toxicologic pathology (01.04.2013)
Published in Toxicologic pathology (01.04.2013)
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Islets of Langerhans from prohormone convertase-2 knockout mice show α-cell hyperplasia and tumorigenesis with elevated α-cell neogenesis
Jones, Huw B., Reens, Jaimini, Brocklehurst, Simon R., Betts, Catherine J., Bickerton, Sue, Bigley, Alison L., Jenkins, Richard P., Whalley, Nicky M., Morgan, Derrick, Smith, David M.
Published in International journal of experimental pathology (01.02.2014)
Published in International journal of experimental pathology (01.02.2014)
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Tissue-specific Expression and Subcellular Distribution of Murine Glutathione S-transferase Class Kappa
Thomson, Rachel E, Bigley, Alison L, Foster, John R, Jowsey, Ian R, Elcombe, Clifford R, Orton, Terry C, Hayes, John D
Published in The journal of histochemistry and cytochemistry (01.05.2004)
Published in The journal of histochemistry and cytochemistry (01.05.2004)
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Miscellaneous: P22: The value of automated cellular imaging on tissue microarrays in the drug-discovery process
Bigley, Alison L., Brocklehurst, Simon R., Randall, Kevin J., Jenkins, Richard P., Wilkinson, Robert W., Heaton, Simon P., Foster, John, Hughes, Gareth D., McKay, Jennifer S.
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.05.2009)
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.05.2009)
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Abstract 4986: Utilizing image analysis to characterize an 8-plex immunofluorescence immune checkpoint biomarker panel within the tumor tissue microenvironment
Bigley, Alison L., Sherry, Lorcan A., Stillie, Nicole, Wood, Douglas, Downing, Sean
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 5686: Utilization of fluorescent multiplex IHC and digital image analysis for studying LAG-3, CD3 and CD8 positive TIL subsets in NSCLC tissue
Khenkhar, Malik, Biljes, Daniel, Winkler, Nickels, Uhlig, Philipp C., Juhl, Hartmut, Bigley, Alison L., Sherry, Lorcan
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Using Skin Biopsies to Measure Target Occupancy of a Renal Antifibrotic Monoclonal Antibody (mAb) in a Phase 1 Clinical Study: PO2267
Bowcutt, Rowann, Johnston, Geoffrey I., Huang, Linghong, Song, James Z., Schmidt, Tim S., Bigley, Alison L., Ogg, Graham, Wong, Eric, Thomson, Elizabeth S., Chan, Jane Y., Raievska, Anastasiia, Johnson, Timothy S.
Published in Journal of the American Society of Nephrology (01.10.2020)
Published in Journal of the American Society of Nephrology (01.10.2020)
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Digital image analysis of automated mRNA in situ hybridization and immunohistochemistry to quantify HER3 expression in cancer tissues
Khenkhar, Malik, Uhlig, Philipp C., David, Kerstin A., Bigley, Alison L., Sherry, Lorcan
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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AZD2171 : A highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer
WEDGE, Stephen R, KENDREW, Jane, CHESTER, Rosemary, JACKSON, Janet A, BOFFEY, Sarah J, KILBURN, Lyndsey L, BARNETT, Sharon, RICHMOND, Graham H. P, WADSWORTH, Peter F, WALKER, Mike, BIGLEY, Alison L, TAYLOR, Sian T, HENNEQUIN, Laurent F, COOPER, Lee, BECK, Sarah, JÜRGENSMEIER, Juliane M, OGILVIE, Donald J, VALENTINE, Paula J, BARRY, Simon T, BRAVE, Sandra R, SMITH, Neil R, JAMES, Neil H, DUKES, Michael, CURWEN, Jon O
Published in Cancer research (Chicago, Ill.) (15.05.2005)
Published in Cancer research (Chicago, Ill.) (15.05.2005)
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Miscellaneous
Bigley, Alison L., Brocklehurst, Simon R., Randall, Kevin J., Jenkins, Richard P., Wilkinson, Robert W., Heaton, Simon P., Foster, John, Hughes, Gareth D., McKay, Jennifer S.
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.05.2009)
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.05.2009)
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