Gene essentiality and synthetic lethality in haploid human cells
Blomen, Vincent A., Májek, Peter, Jae, Lucas T., Bigenzahn, Johannes W., Nieuwenhuis, Joppe, Staring, Jacqueline, Sacco, Roberto, van Diemen, Ferdy R., Olk, Nadine, Stukalov, Alexey, Marceau, Caleb, Janssen, Hans, Carette, Jan E., Bennett, Keiryn L., Colinge, Jacques, Superti-Furga, Giulio, Brummelkamp, Thijn R.
Published in Science (American Association for the Advancement of Science) (27.11.2015)
Published in Science (American Association for the Advancement of Science) (27.11.2015)
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Journal Article
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9
Heinz, Leonhard X, Lee, JangEun, Kapoor, Utkarsh, Kartnig, Felix, Sedlyarov, Vitaly, Papakostas, Konstantinos, César-Razquin, Adrian, Essletzbichler, Patrick, Goldmann, Ulrich, Stefanovic, Adrijana, Bigenzahn, Johannes W, Scorzoni, Stefania, Pizzagalli, Mattia D, Bensimon, Ariel, Müller, André C, King, F James, Li, Jun, Girardi, Enrico, Mbow, M Lamine, Whitehurst, Charles E, Rebsamen, Manuele, Superti-Furga, Giulio
Published in Nature (London) (01.05.2020)
Published in Nature (London) (01.05.2020)
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Journal Article
Recent advances in combinatorial drug screening and synergy scoring
Pemovska, Tea, Bigenzahn, Johannes W, Superti-Furga, Giulio
Published in Current opinion in pharmacology (01.10.2018)
Published in Current opinion in pharmacology (01.10.2018)
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Journal Article
The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification
Sedlyarov, Vitaly, Eichner, Ruth, Girardi, Enrico, Essletzbichler, Patrick, Goldmann, Ulrich, Nunes-Hasler, Paula, Srndic, Ismet, Moskovskich, Anna, Heinz, Leonhard X., Kartnig, Felix, Bigenzahn, Johannes W., Rebsamen, Manuele, Kovarik, Pavel, Demaurex, Nicolas, Superti-Furga, Giulio
Published in Cell host & microbe (13.06.2018)
Published in Cell host & microbe (13.06.2018)
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Journal Article
Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking
Fauster, Astrid, Rebsamen, Manuele, Willmann, Katharina L, César-Razquin, Adrian, Girardi, Enrico, Bigenzahn, Johannes W, Schischlik, Fiorella, Scorzoni, Stefania, Bruckner, Manuela, Konecka, Justyna, Hörmann, Katrin, Heinz, Leonhard X, Boztug, Kaan, Superti-Furga, Giulio
Published in Cell death and differentiation (01.06.2019)
Published in Cell death and differentiation (01.06.2019)
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Journal Article
Metabolic drug survey highlights cancer cell dependencies and vulnerabilities
Pemovska, Tea, Bigenzahn, Johannes W, Srndic, Ismet, Lercher, Alexander, Bergthaler, Andreas, César-Razquin, Adrián, Kartnig, Felix, Kornauth, Christoph, Valent, Peter, Staber, Philipp B, Superti-Furga, Giulio
Published in Nature communications (14.12.2021)
Published in Nature communications (14.12.2021)
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Journal Article
The Comparability of Anti-Spike SARS-CoV-2 Antibody Tests is Time-Dependent: a Prospective Observational Study
Perkmann, Thomas, Mucher, Patrick, Perkmann-Nagele, Nicole, Radakovics, Astrid, Repl, Manuela, Koller, Thomas, Schmetterer, Klaus G, Bigenzahn, Johannes W, Leitner, Florentina, Jordakieva, Galateja, Wagner, Oswald F, Binder, Christoph J, Haslacher, Helmuth
Published in Microbiology spectrum (23.02.2022)
Published in Microbiology spectrum (23.02.2022)
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Journal Article
An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client
Bigenzahn, Johannes W., Fauster, Astrid, Rebsamen, Manuele, Kandasamy, Richard K., Scorzoni, Stefania, Vladimer, Gregory I., Müller, André C., Gstaiger, Matthias, Zuber, Johannes, Bennett, Keiryn L., Superti-Furga, Giulio
Published in Molecular & cellular proteomics (01.03.2016)
Published in Molecular & cellular proteomics (01.03.2016)
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Journal Article
Identifying Kinase Substrates via a Heavy ATP Kinase Assay and Quantitative Mass Spectrometry
Müller, André C, Giambruno, Roberto, Weißer, Juliane, Májek, Peter, Hofer, Alexandre, Bigenzahn, Johannes W, Superti-Furga, Giulio, Jessen, Henning J, Bennett, Keiryn L
Published in Scientific reports (27.06.2016)
Published in Scientific reports (27.06.2016)
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Journal Article
Global survey of the immunomodulatory potential of common drugs
Vladimer, Gregory I, Snijder, Berend, Krall, Nikolaus, Bigenzahn, Johannes W, Huber, Kilian V M, Lardeau, Charles-Hugues, Sanjiv, Kumar, Ringler, Anna, Berglund, Ulrika Warpman, Sabler, Monika, de la Fuente, Oscar Lopez, Knöbl, Paul, Kubicek, Stefan, Helleday, Thomas, Jäger, Ulrich, Superti-Furga, Giulio
Published in Nature chemical biology (01.06.2017)
Published in Nature chemical biology (01.06.2017)
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Journal Article
High risk of unilateral recurrent laryngeal nerve paralysis after esophagectomy using cervical anastomosis
Pertl, L., Zacherl, J., Mancusi, G., Gächter, J. N., Asari, R., Schoppmann, S., Bigenzahn, W., Schneider-Stickler, B.
Published in European archives of oto-rhino-laryngology (01.11.2011)
Published in European archives of oto-rhino-laryngology (01.11.2011)
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Journal Article
Superimposed high-frequency jet ventilation (SHFJV) for endoscopic laryngotracheal surgery in more than 1500 patients
Rezaie-Majd, A., Bigenzahn, W., Denk, D.-M., Burian, M., Kornfehl, J., Grasl, M.Ch, Ihra, G., Aloy, A.
Published in British journal of anaesthesia : BJA (01.05.2006)
Published in British journal of anaesthesia : BJA (01.05.2006)
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Journal Article
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
Rebsamen, Manuele, Pochini, Lorena, Stasyk, Taras, de Araújo, Mariana E G, Galluccio, Michele, Kandasamy, Richard K, Snijder, Berend, Fauster, Astrid, Rudashevskaya, Elena L, Bruckner, Manuela, Scorzoni, Stefania, Filipek, Przemyslaw A, Huber, Kilian V M, Bigenzahn, Johannes W, Heinz, Leonhard X, Kraft, Claudine, Bennett, Keiryn L, Indiveri, Cesare, Huber, Lukas A, Superti-Furga, Giulio
Published in Nature (London) (26.03.2015)
Published in Nature (London) (26.03.2015)
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Journal Article
LZTR1 is a regulator of RAS ubiquitination and signaling
Bigenzahn, Johannes W, Collu, Giovanna M, Kartnig, Felix, Pieraks, Melanie, Vladimer, Gregory I, Heinz, Leonhard X, Sedlyarov, Vitaly, Schischlik, Fiorella, Fauster, Astrid, Rebsamen, Manuele, Parapatics, Katja, Blomen, Vincent A, Müller, André C, Winter, Georg E, Kralovics, Robert, Brummelkamp, Thijn R, Mlodzik, Marek, Superti-Furga, Giulio
Published in Science (American Association for the Advancement of Science) (07.12.2018)
Published in Science (American Association for the Advancement of Science) (07.12.2018)
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Journal Article
Identification and Characterization of Novel Small-Molecule Enhancers of the CUL3LZTR1 E3 Ligase KRAS Complex
Piech, Sophie, Brüschweiler, Sven, Westphalen, Josepha, Siess, Katharina M, García Murias, Julio, Konrat, Robert, Bigenzahn, Johannes W, Superti-Furga, Giulio
Published in ACS chemical biology (28.08.2024)
Published in ACS chemical biology (28.08.2024)
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Journal Article
JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia
Boztug, Kaan, Järvinen, Päivi M, Salzer, Elisabeth, Racek, Tomas, Mönch, Sebastian, Garncarz, Wojciech, Gertz, E Michael, Schäffer, Alejandro A, Antonopoulos, Aristotelis, Haslam, Stuart M, Schieck, Lena, Puchałka, Jacek, Diestelhorst, Jana, Appaswamy, Giridharan, Lescoeur, Brigitte, Giambruno, Roberto, Bigenzahn, Johannes W, Elling, Ulrich, Pfeifer, Dietmar, Conde, Cecilia Domínguez, Albert, Michael H, Welte, Karl, Brandes, Gudrun, Sherkat, Roya, van der Werff Ten Bosch, Jutte, Rezaei, Nima, Etzioni, Amos, Bellanné-Chantelot, Christine, Superti-Furga, Giulio, Penninger, Josef M, Bennett, Keiryn L, von Blume, Julia, Dell, Anne, Donadieu, Jean, Klein, Christoph
Published in Nature genetics (01.09.2014)
Published in Nature genetics (01.09.2014)
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Journal Article
Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study
Snijder, Berend, Vladimer, Gregory I, Krall, Nikolaus, Miura, Katsuhiro, Schmolke, Ann-Sofie, Kornauth, Christoph, Lopez de la Fuente, Oscar, Choi, Hye-Soo, van der Kouwe, Emiel, Gültekin, Sinan, Kazianka, Lukas, Bigenzahn, Johannes W, Hoermann, Gregor, Prutsch, Nicole, Merkel, Olaf, Ringler, Anna, Sabler, Monika, Jeryczynski, Georg, Mayerhoefer, Marius E, Simonitsch-Klupp, Ingrid, Ocko, Katharina, Felberbauer, Franz, Müllauer, Leonhard, Prager, Gerald W, Korkmaz, Belgin, Kenner, Lukas, Sperr, Wolfgang R, Kralovics, Robert, Gisslinger, Heinz, Valent, Peter, Kubicek, Stefan, Jäger, Ulrich, Staber, Philipp B, Superti-Furga, Giulio
Published in The Lancet. Haematology (01.12.2017)
Published in The Lancet. Haematology (01.12.2017)
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Journal Article
The RNA‐binding protein HuR/ELAVL1 regulates IFN‐β mRNA abundance and the type I IFN response
Herdy, Barbara, Karonitsch, Thomas, Vladimer, Gregory I., Tan, Chris S.H., Stukalov, Alexey, Trefzer, Claudia, Bigenzahn, Johannes W., Theil, Tamara, Holinka, Johannes, Kiener, Hans P., Colinge, Jacques, Bennett, Keiryn L, Superti‐Furga, Giulio
Published in European journal of immunology (01.05.2015)
Published in European journal of immunology (01.05.2015)
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Journal Article
Implementation of the Vienna Hydrotherapy Group for Laryngectomees--a pilot study
Crevenna, R, Schneider, B, Mittermaier, C, Keilani, M, Zöch, C, Nuhr, M, Wolzt, M, Quittan, M, Bigenzahn, W, Fialka-Moser, V
Published in Supportive care in cancer (01.11.2003)
Published in Supportive care in cancer (01.11.2003)
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