Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells
Karampini, Ellie, Schillemans, Maaike, Hofman, Menno, van Alphen, Floris, de Boer, Martin, Kuijpers, Taco W, van den Biggelaar, Maartje, Voorberg, Jan, Bierings, Ruben
Published in Haematologica (Roma) (01.10.2019)
Published in Haematologica (Roma) (01.10.2019)
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Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells
Schillemans, Maaike, Karampini, Ellie, van den Eshof, Bart L, Gangaev, Anastasia, Hofman, Menno, van Breevoort, Dorothee, Meems, Henriët, Janssen, Hans, Mulder, Aat A, Jost, Carolina R, Escher, Johanna C, Adam, Rüdiger, Carter, Tom, Koster, Abraham J, van den Biggelaar, Maartje, Voorberg, Jan, Bierings, Ruben
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2018)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2018)
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Journal Article
Syntaxin 5 determines Weibel-Palade body size and Von Willebrand factor secretion by controlling Golgi architecture
Kat, Marije, Karampini, Ellie, Hoogendijk, Arie J, Bürgisser, Petra E, Mulder, Aat A, Van Alphen, Floris P J, Olins, Jenny, Geerts, Dirk, Van den Biggelaar, Maartje, Margadant, Coert, Voorberg, Jan, Bierings, Ruben
Published in Haematologica (Roma) (01.08.2022)
Published in Haematologica (Roma) (01.08.2022)
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Altered Storage and Function of von Willebrand Factor in Human Cardiac Microvascular Endothelial Cells Isolated from Recipient Transplant Hearts
Meli, Athinoula, McCormack, Ann, Conte, Ianina, Chen, Qu, Streetley, James, Rose, Marlene L, Bierings, Ruben, Hannah, Matthew J, Molloy, Justin E, Rosenthal, Peter B, Carter, Tom
Published in International journal of molecular sciences (25.02.2023)
Published in International journal of molecular sciences (25.02.2023)
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The interplay between the Rab27A effectors Slp4-a and MyRIP controls hormone-evoked Weibel-Palade body exocytosis
Bierings, Ruben, Hellen, Nicola, Kiskin, Nikolai, Knipe, Laura, Fonseca, Ana-Violeta, Patel, Bijal, Meli, Athina, Rose, Marlene, Hannah, Matthew J., Carter, Tom
Published in Blood (27.09.2012)
Published in Blood (27.09.2012)
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Dynamics and Plasticity of Weibel-Palade Bodies in Endothelial Cells
Rondaij, Mariska G, Bierings, Ruben, Kragt, Astrid, van Mourik, Jan A, Voorberg, Jan
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2006)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2006)
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Journal Article
Interaction between MyRIP and the actin cytoskeleton regulates Weibel-Palade body trafficking and exocytosis
Conte, Ianina L, Hellen, Nicola, Bierings, Ruben, Mashanov, Gregory I, Manneville, Jean-Baptiste, Kiskin, Nikolai I, Hannah, Matthew J, Molloy, Justin E, Carter, Tom
Published in Journal of cell science (01.02.2016)
Published in Journal of cell science (01.02.2016)
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A revised model for the secretion of tPA and cytokines from cultured endothelial cells
Knipe, Laura, Meli, Athinoula, Hewlett, Lindsay, Bierings, Ruben, Dempster, John, Skehel, Paul, Hannah, Matthew J., Carter, Tom
Published in Blood (23.09.2010)
Published in Blood (23.09.2010)
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A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation
Rijkers, Maaike, Saris, Anno, Heidt, Sebastiaan, Mulder, Arend, Porcelijn, Leendert, Claas, Frans H J, Bierings, Ruben, Leebeek, Frank W G, Jansen, A J Gerard, Vidarsson, Gestur, Voorberg, Jan, de Haas, Masja
Published in Haematologica (Roma) (01.10.2018)
Published in Haematologica (Roma) (01.10.2018)
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Journal Article
Proteomic Screen Identifies IGFBP7 as a Novel Component of Endothelial Cell-Specific Weibel-Palade Bodies
van Breevoort, Dorothee, van Agtmaal, Ellen L, Dragt, Bieuwke S, Gebbinck, Jacqueline Klein, Dienava-Verdoold, Ilze, Kragt, Astrid, Bierings, Ruben, Horrevoets, Anton J. G, Valentijn, Karine M, Eikenboom, Jeroen C, Fernandez-Borja, Mar, Meijer, Alexander B, Voorberg, Jan
Published in Journal of proteome research (04.05.2012)
Published in Journal of proteome research (04.05.2012)
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Generation and characterization of a control and patient-derived human iPSC line containing the Hermansky Pudlak type 2 (HPS2) associated heterozygous compound mutation in AP3B1
Aarts, Cathelijn E.M., Karampini, Ellie, Wüst, Tatjana, Webbers, Steven, Varga, Eszter, Geissler, Judy, Voorberg, Jan, von Lindern, Marieke, Bierings, Ruben, van den Akker, Emile, Kuijpers, Taco W.
Published in Stem cell research (01.07.2021)
Published in Stem cell research (01.07.2021)
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Journal Article
Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor
Smeets, Michel W J, Bierings, Ruben, Meems, Henriet, Mul, Frederik P J, Geerts, Dirk, Vlaar, Alexander P J, Voorberg, Jan, Hordijk, Peter L
Published in PloS one (01.03.2017)
Published in PloS one (01.03.2017)
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Journal Article
The Epac-Rap1 Signaling Pathway Controls cAMP-mediated Exocytosis of Weibel-Palade Bodies in Endothelial Cells
van Hooren, Kathinka W.E.M., van Agtmaal, Ellen L., Fernandez-Borja, Mar, van Mourik, Jan A., Voorberg, Jan, Bierings, Ruben
Published in The Journal of biological chemistry (13.07.2012)
Published in The Journal of biological chemistry (13.07.2012)
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Journal Article
Correction: Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor
Smeets, Michel W J, Bierings, Ruben, Meems, Henriet, Mul, Frederik P J, Geerts, Dirk, Vlaar, Alexander P J, Voorberg, Jan, Hordijk, Peter L
Published in PloS one (21.03.2018)
Published in PloS one (21.03.2018)
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Journal Article
The shear stress-induced transcription factor KLF2 affects dynamics and angiopoietin-2 content of Weibel-Palade bodies
van Agtmaal, Ellen L, Bierings, Ruben, Dragt, Bieuwke S, Leyen, Thomas A, Fernandez-Borja, Mar, Horrevoets, Anton J G, Voorberg, Jan
Published in PloS one (08.06.2012)
Published in PloS one (08.06.2012)
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Quantitative 3D microscopy highlights altered von Willebrand factor α‐granule storage in patients with von Willebrand disease with distinct pathogenic mechanisms
Swinkels, Maurice, Atiq, Ferdows, Bürgisser, Petra E., Slotman, Johan A., Houtsmuller, Adriaan B., de Heus, Cilia, Klumperman, Judith, Leebeek, Frank W.G., Voorberg, Jan, Jansen, Arend Jan Gerard, Bierings, Ruben
Published in Research and practice in thrombosis and haemostasis (01.08.2021)
Published in Research and practice in thrombosis and haemostasis (01.08.2021)
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Journal Article
Sphingosine-1-phosphate receptor 3 mediates sphingosine-1-phosphate induced release of weibel-palade bodies from endothelial cells
van Hooren, Kathinka W E M, Spijkers, Léon J A, van Breevoort, Dorothee, Fernandez-Borja, Mar, Bierings, Ruben, van Buul, Jaap D, Alewijnse, Astrid E, Peters, Stephan L M, Voorberg, Jan
Published in PloS one (14.03.2014)
Published in PloS one (14.03.2014)
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