Genome doubling shapes the evolution and prognosis of advanced cancers
Bielski, Craig M, Zehir, Ahmet, Penson, Alexander V, Donoghue, Mark T A, Chatila, Walid, Armenia, Joshua, Chang, Matthew T, Schram, Alison M, Jonsson, Philip, Bandlamudi, Chaitanya, Razavi, Pedram, Iyer, Gopa, Robson, Mark E, Stadler, Zsofia K, Schultz, Nikolaus, Baselga, Jose, Solit, David B, Hyman, David M, Berger, Michael F, Taylor, Barry S
Published in Nature genetics (01.08.2018)
Published in Nature genetics (01.08.2018)
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Tumour lineage shapes BRCA-mediated phenotypes
Jonsson, Philip, Bandlamudi, Chaitanya, Cheng, Michael L, Srinivasan, Preethi, Chavan, Shweta S, Friedman, Noah D, Rosen, Ezra Y, Richards, Allison L, Bouvier, Nancy, Selcuklu, S Duygu, Bielski, Craig M, Abida, Wassim, Mandelker, Diana, Birsoy, Ozge, Zhang, Liying, Zehir, Ahmet, Donoghue, Mark T A, Baselga, José, Offit, Kenneth, Scher, Howard I, O'Reilly, Eileen M, Stadler, Zsofia K, Schultz, Nikolaus, Socci, Nicholas D, Viale, Agnes, Ladanyi, Marc, Robson, Mark E, Hyman, David M, Berger, Michael F, Solit, David B, Taylor, Barry S
Published in Nature (London) (01.07.2019)
Published in Nature (London) (01.07.2019)
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MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells
Kryukov, Gregory V., Wilson, Frederick H., Ruth, Jason R., Paulk, Joshiawa, Tsherniak, Aviad, Marlow, Sara E., Vazquez, Francisca, Weir, Barbara A., Fitzgerald, Mark E., Tanaka, Minoru, Bielski, Craig M., Scott, Justin M., Dennis, Courtney, Cowley, Glenn S., Boehm, Jesse S., Root, David E., Golub, Todd R., Clish, Clary B., Bradner, James E., Hahn, William C., Garraway, Levi A.
Published in Science (American Association for the Advancement of Science) (11.03.2016)
Published in Science (American Association for the Advancement of Science) (11.03.2016)
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Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis
Scher, Jose U, Sczesnak, Andrew, Longman, Randy S, Segata, Nicola, Ubeda, Carles, Bielski, Craig, Rostron, Tim, Cerundolo, Vincenzo, Pamer, Eric G, Abramson, Steven B, Huttenhower, Curtis, Littman, Dan R
Published in eLife (05.11.2013)
Published in eLife (05.11.2013)
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KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer
Burgess, Michael R., Hwang, Eugene, Mroue, Rana, Bielski, Craig M., Wandler, Anica M., Huang, Benjamin J., Firestone, Ari J., Young, Amy, Lacap, Jennifer A., Crocker, Lisa, Asthana, Saurabh, Davis, Elizabeth M., Xu, Jin, Akagi, Keiko, Le Beau, Michelle M., Li, Qing, Haley, Benjamin, Stokoe, David, Sampath, Deepak, Taylor, Barry S., Evangelista, Marie, Shannon, Kevin
Published in Cell (23.02.2017)
Published in Cell (23.02.2017)
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The context-specific role of germline pathogenicity in tumorigenesis
Srinivasan, Preethi, Bandlamudi, Chaitanya, Jonsson, Philip, Kemel, Yelena, Chavan, Shweta S, Richards, Allison L, Penson, Alexander V, Bielski, Craig M, Fong, Christopher, Syed, Aijazuddin, Jayakumaran, Gowtham, Prasad, Meera, Hwee, Jason, Sumer, Selcuk Onur, de Bruijn, Ino, Li, Xiang, Gao, JianJiong, Schultz, Nikolaus, Cambria, Roy, Galle, Jesse, Mukherjee, Semanti, Vijai, Joseph, Cadoo, Karen A, Carlo, Maria I, Walsh, Michael F, Mandelker, Diana, Ceyhan-Birsoy, Ozge, Shia, Jinru, Zehir, Ahmet, Ladanyi, Marc, Hyman, David M, Zhang, Liying, Offit, Kenneth, Robson, Mark E, Solit, David B, Stadler, Zsofia K, Berger, Michael F, Taylor, Barry S
Published in Nature genetics (01.11.2021)
Published in Nature genetics (01.11.2021)
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Phase and context shape the function of composite oncogenic mutations
Gorelick, Alexander N, Sánchez-Rivera, Francisco J, Cai, Yanyan, Bielski, Craig M, Biederstedt, Evan, Jonsson, Philip, Richards, Allison L, Vasan, Neil, Penson, Alexander V, Friedman, Noah D, Ho, Yu-Jui, Baslan, Timour, Bandlamudi, Chaitanya, Scaltriti, Maurizio, Schultz, Nikolaus, Lowe, Scott W, Reznik, Ed, Taylor, Barry S
Published in Nature (London) (01.06.2020)
Published in Nature (London) (01.06.2020)
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Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer
Bielski, Craig M., Donoghue, Mark T.A., Gadiya, Mayur, Hanrahan, Aphrothiti J., Won, Helen H., Chang, Matthew T., Jonsson, Philip, Penson, Alexander V., Gorelick, Alexander, Harris, Christopher, Schram, Alison M., Syed, Aijazuddin, Zehir, Ahmet, Chapman, Paul B., Hyman, David M., Solit, David B., Shannon, Kevin, Chandarlapaty, Sarat, Berger, Michael F., Taylor, Barry S.
Published in Cancer cell (12.11.2018)
Published in Cancer cell (12.11.2018)
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EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer
Oldrini, Barbara, Hsieh, Wan-Ying, Erdjument-Bromage, Hediye, Codega, Paolo, Carro, Maria Stella, Curiel-García, Alvaro, Campos, Carl, Pourmaleki, Maryam, Grommes, Christian, Vivanco, Igor, Rohle, Daniel, Bielski, Craig M, Taylor, Barry S, Hollmann, Travis J, Rosenblum, Marc, Tempst, Paul, Blenis, John, Squatrito, Massimo, Mellinghoff, Ingo K
Published in Nature communications (11.12.2017)
Published in Nature communications (11.12.2017)
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The Genetic Evolution of Treatment-Resistant Cutaneous, Acral, and Uveal Melanomas
Makohon-Moore, Alvin P, Lipson, Evan J, Hooper, Jody E, Zucker, Amanda, Hong, Jungeui, Bielski, Craig M, Hayashi, Akimasa, Tokheim, Collin, Baez, Priscilla, Kappagantula, Rajya, Kohutek, Zachary, Makarov, Vladimir, Riaz, Nadeem, Postow, Michael A, Chapman, Paul B, Karchin, Rachel, Socci, Nicholas D, Solit, David B, Chan, Timothy A, Taylor, Barry S, Topalian, Suzanne L, Iacobuzio-Donahue, Christine A
Published in Clinical cancer research (01.03.2021)
Published in Clinical cancer research (01.03.2021)
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Accelerating Discovery of Functional Mutant Alleles in Cancer
Chang, Matthew T, Bhattarai, Tripti Shrestha, Schram, Alison M, Bielski, Craig M, Donoghue, Mark T A, Jonsson, Philip, Chakravarty, Debyani, Phillips, Sarah, Kandoth, Cyriac, Penson, Alexander, Gorelick, Alexander, Shamu, Tambudzai, Patel, Swati, Harris, Christopher, Gao, JianJiong, Sumer, Selcuk Onur, Kundra, Ritika, Razavi, Pedram, Li, Bob T, Reales, Dalicia N, Socci, Nicholas D, Jayakumaran, Gowtham, Zehir, Ahmet, Benayed, Ryma, Arcila, Maria E, Chandarlapaty, Sarat, Ladanyi, Marc, Schultz, Nikolaus, Baselga, José, Berger, Michael F, Rosen, Neal, Solit, David B, Hyman, David M, Taylor, Barry S
Published in Cancer discovery (01.02.2018)
Published in Cancer discovery (01.02.2018)
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Genetic Effect of Chemotherapy Exposure in Children of Testicular Cancer Survivors
Kryukov, Gregory V, Bielski, Craig M, Samocha, Kaitlin, Fromer, Menachem, Seepo, Sara, Gentry, Carleen, Neale, Benjamin, Garraway, Levi A, Sweeney, Christopher J, Taplin, Mary-Ellen, Van Allen, Eliezer M
Published in Clinical cancer research (01.05.2016)
Published in Clinical cancer research (01.05.2016)
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Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors
Janouskova, Hana, El Tekle, Geniver, Bellini, Elisa, Udeshi, Namrata D, Rinaldi, Anna, Ulbricht, Anna, Bernasocchi, Tiziano, Civenni, Gianluca, Losa, Marco, Svinkina, Tanya, Bielski, Craig M, Kryukov, Gregory V, Cascione, Luciano, Napoli, Sara, Enchev, Radoslav I, Mutch, David G, Carney, Michael E, Berchuck, Andrew, Winterhoff, Boris J N, Broaddus, Russell R, Schraml, Peter, Moch, Holger, Bertoni, Francesco, Catapano, Carlo V, Peter, Matthias, Carr, Steven A, Garraway, Levi A, Wild, Peter J, Theurillat, Jean-Philippe P
Published in Nature medicine (01.09.2017)
Published in Nature medicine (01.09.2017)
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The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers
Rosen, Ezra Y, Won, Helen H, Zheng, Youyun, Cocco, Emiliano, Selcuklu, Duygu, Gong, Yixiao, Friedman, Noah D, de Bruijn, Ino, Sumer, Onur, Bielski, Craig M, Savin, Casey, Bourque, Caitlin, Falcon, Christina, Clarke, Nikeysha, Jing, Xiaohong, Meng, Fanli, Zimel, Catherine, Shifman, Sophie, Kittane, Srushti, Wu, Fan, Ladanyi, Marc, Ebata, Kevin, Kherani, Jennifer, Brandhuber, Barbara J, Fagin, James, Sherman, Eric J, Rekhtman, Natasha, Berger, Michael F, Scaltriti, Maurizio, Hyman, David M, Taylor, Barry S, Drilon, Alexander
Published in Nature communications (18.03.2022)
Published in Nature communications (18.03.2022)
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Author Correction: Tumour lineage shapes BRCA-mediated phenotypes
Jonsson, Philip, Bandlamudi, Chaitanya, Cheng, Michael L, Srinivasan, Preethi, Chavan, Shweta S, Friedman, Noah D, Rosen, Ezra Y, Richards, Allison L, Bouvier, Nancy, Selcuklu, S Duygu, Bielski, Craig M, Abida, Wassim, Mandelker, Diana, Birsoy, Ozge, Zhang, Liying, Zehir, Ahmet, Donoghue, Mark T A, Baselga, José, Offit, Kenneth, Scher, Howard I, O'Reilly, Eileen M, Stadler, Zsofia K, Schultz, Nikolaus, Socci, Nicholas D, Viale, Agnes, Ladanyi, Marc, Robson, Mark E, Hyman, David M, Berger, Michael F, Solit, David B, Taylor, Barry S
Published in Nature (London) (09.01.2020)
Published in Nature (London) (09.01.2020)
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Publisher Correction: The long tail of oncogenic drivers in prostate cancer
Armenia, Joshua, Wankowicz, Stephanie A M, Liu, David, Gao, Jianjiong, Kundra, Ritika, Reznik, Ed, Chatila, Walid K, Chakravarty, Debyani, Han, G Celine, Coleman, Ilsa, Montgomery, Bruce, Pritchard, Colin, Morrissey, Colm, Barbieri, Christopher E, Beltran, Himisha, Sboner, Andrea, Zafeiriou, Zafeiris, Miranda, Susana, Bielski, Craig M, Penson, Alexander V, Tolonen, Charlotte, Huang, Franklin W, Robinson, Dan, Wu, Yi Mi, Lonigro, Robert, Garraway, Levi A, Demichelis, Francesca, Kantoff, Philip W, Taplin, Mary-Ellen, Abida, Wassim, Taylor, Barry S, Scher, Howard I, Nelson, Peter S, de Bono, Johann S, Rubin, Mark A, Sawyers, Charles L, Chinnaiyan, Arul M, Schultz, Nikolaus, Van Allen, Eliezer M
Published in Nature genetics (01.07.2019)
Published in Nature genetics (01.07.2019)
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The Evolutionary Origins of Recurrent Pancreatic Cancer
Sakamoto, Hitomi, Attiyeh, Marc A, Gerold, Jeffrey M, Makohon-Moore, Alvin P, Hayashi, Akimasa, Hong, Jungeui, Kappagantula, Rajya, Zhang, Lance, Melchor, Jerry P, Reiter, Johannes G, Heyde, Alexander, Bielski, Craig M, Penson, Alexander V, Gönen, Mithat, Chakravarty, Debyani, O'Reilly, Eileen M, Wood, Laura D, Hruban, Ralph H, Nowak, Martin A, Socci, Nicholas D, Taylor, Barry S, Iacobuzio-Donahue, Christine A
Published in Cancer discovery (01.06.2020)
Published in Cancer discovery (01.06.2020)
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Same-Cell Co-Occurrence of RAS Hotspot and BRAF V600E Mutations in Treatment-Naive Colorectal Cancer
Gularte-Mérida, Rodrigo, Smith, Shaleigh, Bowman, Anita S, da Cruz Paula, Arnaud, Chatila, Walid, Bielski, Craig M, Vyas, Monika, Borsu, Laetitia, Zehir, Ahmet, Martelotto, Luciano G, Shia, Jinru, Yaeger, Rona, Fang, Fang, Gardner, Rui, Luo, Ruibang, Schatz, Michael C, Shen, Ronglai, Weigelt, Britta, Sánchez-Vega, Francisco, Reis-Filho, Jorge S, Hechtman, Jaclyn F
Published in JCO precision oncology (01.03.2022)
Published in JCO precision oncology (01.03.2022)
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