CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis
Schneider, Kai Markus, Bieghs, Veerle, Heymann, Felix, Hu, Wei, Dreymueller, Daniela, Liao, Lijun, Frissen, Mick, Ludwig, Andreas, Gassler, Nikolaus, Pabst, Oliver, Latz, Eicke, Sellge, Gernot, Penders, John, Tacke, Frank, Trautwein, Christian
Published in Hepatology (Baltimore, Md.) (01.11.2015)
Published in Hepatology (Baltimore, Md.) (01.11.2015)
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Journal Article
Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
Wouters, Kristiaan, van Gorp, Patrick J., Bieghs, Veerle, Gijbels, Marion J., Duimel, Hans, Lütjohann, Dieter, Kerksiek, Anja, van Kruchten, Roger, Maeda, Nobuyo, Staels, Bart, van Bilsen, Marc, Shiri‐Sverdlov, Ronit, Hofker, Marten H.
Published in Hepatology (Baltimore, Md.) (01.08.2008)
Published in Hepatology (Baltimore, Md.) (01.08.2008)
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Journal Article
Non-alcoholic steatohepatitis: The role of oxidized low-density lipoproteins
Walenbergh, Sofie M.A, Koek, Ger H, Bieghs, Veerle, Shiri-Sverdlov, Ronit
Published in Journal of hepatology (01.04.2013)
Published in Journal of hepatology (01.04.2013)
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Journal Article
NASH and atherosclerosis are two aspects of a shared disease: Central role for macrophages
Bieghs, Veerle, Rensen, Patrick C.N, Hofker, Marten H, Shiri-Sverdlov, Ronit
Published in Atherosclerosis (01.02.2012)
Published in Atherosclerosis (01.02.2012)
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Journal Article
LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease
Bieghs, Veerle, Van Gorp, Patrick J, Wouters, Kristiaan, Hendrikx, Tim, Gijbels, Marion J, van Bilsen, Marc, Bakker, Jaap, Binder, Christoph J, Lütjohann, Dieter, Staels, Bart, Hofker, Marten H, Shiri-Sverdlov, Ronit
Published in PloS one (25.01.2012)
Published in PloS one (25.01.2012)
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Journal Article
Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells
Bieghs, Veerle, Verheyen, Fons, van Gorp, Patrick J, Hendrikx, Tim, Wouters, Kristiaan, Lütjohann, Dieter, Gijbels, Marion J J, Febbraio, Maria, Binder, Christoph J, Hofker, Marten H, Shiri-Sverdlov, Ronit
Published in PloS one (28.03.2012)
Published in PloS one (28.03.2012)
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Journal Article
Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice
Bieghs, Veerle, Wouters, Kristiaan, van Gorp, Patrick J, Gijbels, Marion J J, de Winther, Menno P J, Binder, Christoph J, Lütjohann, Dieter, Febbraio, Maria, Moore, Kathryn J, van Bilsen, Marc, Hofker, Marten H, Shiri-Sverdlov, Ronit
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2010)
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Journal Article
Specific immunization strategies against oxidized low-density lipoprotein: A novel way to reduce nonalcoholic steatohepatitis in mice
Bieghs, Veerle, van Gorp, Patrick J., Walenbergh, Sofie M.A., Gijbels, Marion J., Verheyen, Fons, Buurman, Wim A., Briles, David E., Hofker, Marten H., Binder, Christoph J., Shiri-Sverdlov, Ronit
Published in Hepatology (Baltimore, Md.) (01.09.2012)
Published in Hepatology (Baltimore, Md.) (01.09.2012)
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Journal Article
Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice
Wouters, Kristiaan, Bilsen, Marc van, Gorp, Patrick J. van, Bieghs, Veerle, Lütjohann, Dieter, Kerksiek, Anja, Staels, Bart, Hofker, Marten H., Shiri-Sverdlov, Ronit
Published in FEBS letters (05.03.2010)
Published in FEBS letters (05.03.2010)
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Journal Article
Bile Acids Activate NLRP3 Inflammasome, Promoting Murine Liver Inflammation or Fibrosis in a Cell Type-Specific Manner
Holtmann, Theresa Maria, Inzaugarat, Maria Eugenia, Knorr, Jana, Geisler, Lukas, Schulz, Marten, Bieghs, Veerle, Frissen, Mick, Feldstein, Ariel E, Tacke, Frank, Trautwein, Christian, Wree, Alexander
Published in Cells (Basel, Switzerland) (01.10.2021)
Published in Cells (Basel, Switzerland) (01.10.2021)
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Journal Article
Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation
Bieghs, Veerle, Walenbergh, Sofie M. A., Hendrikx, Tim, van Gorp, Patrick J., Verheyen, Fons, Olde Damink, Steven W., Masclee, Ad A., Koek, Ger H., Hofker, Marten H., Binder, Christoph J., Shiri-Sverdlov, Ronit
Published in Liver international (01.08.2013)
Published in Liver international (01.08.2013)
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Journal Article
Protective role of plant sterol and stanol esters in liver inflammation: insights from mice and humans
Plat, Jogchum, Hendrikx, Tim, Bieghs, Veerle, Jeurissen, Mike L J, Walenbergh, Sofie M A, van Gorp, Patrick J, De Smet, Els, Konings, Maurice, Vreugdenhil, Anita C E, Guichot, Yasmin Dias, Rensen, Sander S, Buurman, Wim A, Greve, Jan Willem M, Lütjohann, Dieter, Mensink, Ronald P, Shiri-Sverdlov, Ronit
Published in PloS one (30.10.2014)
Published in PloS one (30.10.2014)
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Journal Article
Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr−/− mice
Hendrikx, Tim, Jeurissen, Mike L.J, Bieghs, Veerle, Walenbergh, Sofie M.A, van Gorp, Patrick J, Verheyen, Fons, Houben, Tom, Guichot, Yasmin Dias, Gijbels, Marion J.J, Leitersdorf, Eran, Hofker, Marten H, Lütjohann, Dieter, Shiri-Sverdlov, Ronit
Published in Journal of hepatology (01.02.2015)
Published in Journal of hepatology (01.02.2015)
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Journal Article
Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice
Hendrikx, Tim, Bieghs, Veerle, Walenbergh, Sofie M A, van Gorp, Patrick J, Verheyen, Fons, Jeurissen, Mike L J, Steinbusch, Mandy M F, Vaes, Nathalie, Binder, Christoph J, Koek, Ger H, Stienstra, Rinke, Netea, Mihai G, Hofker, Marten H, Shiri-Sverdlov, Ronit
Published in PloS one (02.12.2013)
Published in PloS one (02.12.2013)
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Journal Article
Neutrophil-derived myeloperoxidase aggravates non-alcoholic steatohepatitis in low-density lipoprotein receptor-deficient mice
Rensen, Sander S, Bieghs, Veerle, Xanthoulea, Sofia, Arfianti, Evi, Bakker, Jaap A, Shiri-Sverdlov, Ronit, Hofker, Marten H, Greve, Jan Willem, Buurman, Wim A
Published in PloS one (20.12.2012)
Published in PloS one (20.12.2012)
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Journal Article
Increased Hepatic Myeloperoxidase Activity in Obese Subjects with Nonalcoholic Steatohepatitis
Rensen, Sander S, Slaats, Yanti, Nijhuis, Jeroen, Jans, Anneke, Bieghs, Veerle, Driessen, Ann, Malle, Ernst, Greve, Jan Willem, Buurman, Wim A
Published in The American journal of pathology (01.10.2009)
Published in The American journal of pathology (01.10.2009)
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