Wnt/β-catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4
Davidson, Kathryn C, Adams, Allison M, Goodson, Jamie M, McDonald, Circe E, Potter, Jennifer C, Berndt, Jason D, Biechele, Travis L, Taylor, Russell J, Moon, Randall T
Published in Proceedings of the National Academy of Sciences - PNAS (20.03.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (20.03.2012)
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Journal Article
WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling
James, Richard G, Davidson, Kathryn C, Bosch, Katherine A, Biechele, Travis L, Robin, Nicholas C, Taylor, Russell J, Major, Michael B, Camp, Nathan D, Fowler, Kerry, Martins, Timothy J, Moon, Randall T
Published in PloS one (05.12.2012)
Published in PloS one (05.12.2012)
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Journal Article
Wnt Signaling Exerts an Antiproliferative Effect on Adult Cardiac Progenitor Cells Through IGFBP3
Oikonomopoulos, Angelos, Sereti, Konstantina-Ioanna, Conyers, Frank, Bauer, Michael, Liao, Annette, Guan, Jian, Crapps, Dylan, Han, Jung-Kyu, Dong, Hanhua, Bayomy, Ahmad F, Fine, Gabriel C, Westerman, Karen, Biechele, Travis L, Moon, Randall T, Force, Thomas, Liao, Ronglih
Published in Circulation research (09.12.2011)
Published in Circulation research (09.12.2011)
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Journal Article
AKT Kinase Activity Is Required for Lithium to Modulate Mood-Related Behaviors in Mice
PAN, Jen Q, LEWIS, Michael C, NEVE, Rachael L, BIECHELE, Travis L, MOON, Randall T, SCOLNICK, Edward M, PETRYSHEN, Tracey L, HAGGARTY, Stephen J, KETTERMAN, Josh K, CLORE, Elizabeth L, RILEY, Misha, RICHARDS, Keenan R, BERRY-SCOTT, Erin, XIULIN LIU, WAGNER, Florence F, HOLSON, Edward B
Published in Neuropsychopharmacology (New York, N.Y.) (01.06.2011)
Published in Neuropsychopharmacology (New York, N.Y.) (01.06.2011)
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Journal Article
Targeted BRAF inhibition impacts survival in melanoma patients with high levels of Wnt/β-catenin signaling
Chien, Andy J, Haydu, Lauren E, Biechele, Travis L, Kulikauskas, Rima M, Rizos, Helen, Kefford, Richard F, Scolyer, Richard A, Moon, Randall T, Long, Georgina V
Published in PloS one (14.04.2014)
Published in PloS one (14.04.2014)
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Journal Article
Regulating the response to targeted MEK inhibition in melanoma: Enhancing apoptosis in NRAS- and BRAF-mutant melanoma cells with Wnt/β-catenin activation
Conrad, William H., Swift, Reyna D., Biechele, Travis L., Kulikauskas, Rima M., Moon, Randall T., Chien, Andy J.
Published in Cell cycle (Georgetown, Tex.) (15.10.2012)
Published in Cell cycle (Georgetown, Tex.) (15.10.2012)
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Journal Article
Wilms Tumor Suppressor WTX Negatively Regulates WNT/ beta -Catenin Signaling
Major, Michael B, Camp, Nathan D, Berndt, Jason D, Yi, XianHua, Goldenberg, Seth J, Hubbert, Charlotte, Biechele, Travis L, Gingras, Anne-Claude, Zheng, Ning, MacCoss, Michael J, Angers, Stephane, Moon, Randall T
Published in Science (American Association for the Advancement of Science) (18.05.2007)
Published in Science (American Association for the Advancement of Science) (18.05.2007)
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Journal Article
The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-β-catenin pathway by targeting Dishevelled for degradation
Moon, Randall T, Angers, Stephane, Thorpe, Chris J, Biechele, Travis L, Goldenberg, Seth J, Zheng, Ning, MacCoss, Michael J
Published in Nature cell biology (01.04.2006)
Published in Nature cell biology (01.04.2006)
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Journal Article
Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness
Cheng, Jiongjia, Tsuda, Masanao, Okolotowicz, Karl, Dwyer, Mary, Bushway, Paul J., Colas, Alexandre R., Lancman, Joseph J., Schade, Dennis, Perea-Gil, Isaac, Bruyneel, Arne A.N., Lee, Jaechol, Vadgama, Nirmal, Quach, Justine, McKeithan, Wesley L., Biechele, Travis L., Wu, Joseph C., Moon, Randall T., Si Dong, P. Duc, Karakikes, Ioannis, Cashman, John R., Mercola, Mark
Published in Cell chemical biology (20.05.2021)
Published in Cell chemical biology (20.05.2021)
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Journal Article
Coexpression of IL-5 and Eotaxin-2 in Mice Creates an Eosinophil-Dependent Model of Respiratory Inflammation with Characteristics of Severe Asthma
Ochkur, Sergei I, Jacobsen, Elizabeth A, Protheroe, Cheryl A, Biechele, Travis L, Pero, Ralph S, McGarry, Michael P, Wang, Huiying, O'Neill, Katie R, Colbert, Dana C, Colby, Thomas V, Shen, Huahao, Blackburn, Michael R, Irvin, Charles C, Lee, James J, Lee, Nancy A
Published in Journal of Immunology (15.06.2007)
Published in Journal of Immunology (15.06.2007)
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Journal Article
Protein Kinase PKN1 Represses Wnt/β-Catenin Signaling in Human Melanoma Cells
James, Richard G., Bosch, Katherine A., Kulikauskas, Rima M., Yang, Peitzu T., Robin, Nick C., Toroni, Rachel A., Biechele, Travis L., Berndt, Jason D., von Haller, Priska D., Eng, Jimmy K., Wolf-Yadlin, Alejandro, Chien, Andy J., Moon, Randall T.
Published in The Journal of biological chemistry (29.11.2013)
Published in The Journal of biological chemistry (29.11.2013)
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Journal Article
Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling
James, Richard G, Biechele, Travis L, Conrad, William H, Camp, Nathan D, Fass, Daniel M, Major, Michael B, Sommer, Karen, Yi, XianHua, Roberts, Brian S, Cleary, Michele A, Arthur, William T, MacCoss, Michael, Rawlings, David J, Haggarty, Stephen J, Moon, Randall T
Published in Science signaling (26.05.2009)
Published in Science signaling (26.05.2009)
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Journal Article
Transcription-based reporters of Wnt/beta-catenin signaling
Biechele, Travis L, Adams, Allison M, Moon, Randall T
Published in Cold Spring Harbor protocols (01.06.2009)
Published in Cold Spring Harbor protocols (01.06.2009)
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Journal Article
Integrative analysis of genome-wide RNA interference screens
Berndt, Jason D, Biechele, Travis L, Moon, Randall T, Major, Michael B
Published in Science signaling (12.05.2009)
Published in Science signaling (12.05.2009)
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Journal Article
Wilms Tumor Suppressor WTX Negatively Regulates WNT/ß-Catenin Signaling
Major, Michael B., Camp, Nathan D., Berndt, Jason D., Yi, XianHua, Goldenberg, Seth J., Hubbert, Charlotte, Biechele, Travis L., Gingras, Anne-Claude, Zheng, Ning, MacCoss, Michael J., Angers, Stephane, Moon, Randall T.
Published in Science (American Association for the Advancement of Science) (18.05.2007)
Published in Science (American Association for the Advancement of Science) (18.05.2007)
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Journal Article
Wilms Tumor Suppressor WTX Negatively Regulates WNT/β-Catenin Signaling
Major, Michael B, Camp, Nathan D, Berndt, Jason D, Yi, XianHua, Goldenberg, Seth J, Hubbert, Charlotte, Biechele, Travis L, Gingras, Anne-Claude, Zheng, Ning, MacCoss, Michael J, Angers, Stephane, Moon, Randall T
Published in Science (American Association for the Advancement of Science) (18.05.2007)
Published in Science (American Association for the Advancement of Science) (18.05.2007)
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Journal Article