The Pharmacology of T Cell Therapies
Milone, Michael C, Bhoj, Vijay G
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Published in Molecular therapy. Methods & clinical development (16.03.2018)
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CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy
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MAVS and MyD88 Are Essential for Innate Immunity but Not Cytotoxic T Lymphocyte Response against Respiratory Syncytial Virus
Bhoj, Vijay G., Sun, Qinmiao, Bhoj, Elizabeth J., Somers, Cynthia, Chen, Xiang, Torres, Juan-Pablo, Mejias, Asuncion, Gomez, Ana M., Jafri, Hasan, Ramilo, Octavio, Chen, Zhijian J.
Published in Proceedings of the National Academy of Sciences - PNAS (16.09.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (16.09.2008)
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Adoptive T cell immunotherapy for medullary thyroid carcinoma targeting GDNF family receptor alpha 4
Bhoj, Vijay G., Li, Lucy, Parvathaneni, Kalpana, Zhang, Zheng, Kacir, Stephen, Arhontoulis, Dimitrios, Zhou, Kenneth, McGettigan-Croce, Bevin, Nunez-Cruz, Selene, Gulendran, Gayathri, Boesteanu, Alina C., Johnson, Laura, Feldman, Michael D., Radaelli, Enrico, Mansfield, Keith, Nasrallah, MacLean, Goydel, Rebecca S., Peng, Haiyong, Rader, Christoph, Milone, Michael C., Siegel, Don L.
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Published in Molecular therapy. Oncolytics (26.03.2021)
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Making inroads to precision medicine for the treatment of autoimmune diseases: Harnessing genomic studies to better diagnose and treat complex disorders
Baglaenko, Yuriy, Wagner, Catriona, Bhoj, Vijay G, Brodin, Petter, Gershwin, M Eric, Graham, Daniel, Invernizzi, Pietro, Kidd, Kenneth K, Korsunsky, Ilya, Levy, Michael, Mammen, Andrew L, Nizet, Victor, Ramirez-Valle, Francisco, Stites, Edward C, Williams, Marc S, Wilson, Michael, Rose, Noel R, Ladd, Virginia, Sirota, Marina
Published in Cambridge prisms. Precision medicine (2023)
Published in Cambridge prisms. Precision medicine (2023)
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Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease
Ellebrecht, Christoph T., Bhoj, Vijay G., Nace, Arben, Choi, Eun Jung, Mao, Xuming, Cho, Michael Jeffrey, Di Zenzo, Giovanni, Lanzavecchia, Antonio, Seykora, John T., Cotsarelis, George, Milone, Michael C., Payne, Aimee S.
Published in Science (American Association for the Advancement of Science) (08.07.2016)
Published in Science (American Association for the Advancement of Science) (08.07.2016)
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Respiratory Syncytial Virus Persistence in the Lungs Correlates with Airway Hyperreactivity in the Mouse Model
Estripeaut, Dora, Torres, Juan Pablo, Somers, Cynthia S., Tagliabue, Claudia, Khokhar, Shama, Bhoj, Vijay G., Grube, Steve M., Wozniakowski, Aneta, Gomez, Ana M., Ramilo, Octavio, Jafri, Hasan S., Mejias, Asuncion
Published in The Journal of infectious diseases (15.11.2008)
Published in The Journal of infectious diseases (15.11.2008)
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Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies
Parker, Kevin R., Migliorini, Denis, Perkey, Eric, Yost, Kathryn E., Bhaduri, Aparna, Bagga, Puneet, Haris, Mohammad, Wilson, Neil E., Liu, Fang, Gabunia, Khatuna, Scholler, John, Montine, Thomas J., Bhoj, Vijay G., Reddy, Ravinder, Mohan, Suyash, Maillard, Ivan, Kriegstein, Arnold R., June, Carl H., Chang, Howard Y., Posey, Avery D., Satpathy, Ansuman T.
Published in Cell (01.10.2020)
Published in Cell (01.10.2020)
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Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell
Ruella, Marco, Xu, Jun, Barrett, David M, Fraietta, Joseph A, Reich, Tyler J, Ambrose, David E, Klichinsky, Michael, Shestova, Olga, Patel, Prachi R, Kulikovskaya, Irina, Nazimuddin, Farzana, Bhoj, Vijay G, Orlando, Elena J, Fry, Terry J, Bitter, Hans, Maude, Shannon L, Levine, Bruce L, Nobles, Christopher L, Bushman, Frederic D, Young, Regina M, Scholler, John, Gill, Saar I, June, Carl H, Grupp, Stephan A, Lacey, Simon F, Melenhorst, J Joseph
Published in Nature medicine (01.10.2018)
Published in Nature medicine (01.10.2018)
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Respiratory syncytial virus (RSV) RNA loads in peripheral blood correlates with disease severity in mice
Torres, Juan Pablo, Gomez, Ana M, Khokhar, Shama, Bhoj, Vijay G, Tagliabue, Claudia, Chang, Michael L, Kiener, Peter A, Revell, Paula A, Ramilo, Octavio, Mejias, Asuncion
Published in Respiratory research (15.09.2010)
Published in Respiratory research (15.09.2010)
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Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy
Bhoj, Vijay G., Arhontoulis, Dimitrios, Wertheim, Gerald, Capobianchi, James, Callahan, Colleen A., Ellebrecht, Christoph T., Obstfeld, Amrom E., Lacey, Simon F., Melenhorst, Jan J., Nazimuddin, Farzana, Hwang, Wei-Ting, Maude, Shannon L., Wasik, Mariusz A., Bagg, Adam, Schuster, Stephen, Feldman, Michael D., Porter, David L., Grupp, Stephen A., June, Carl H., Milone, Michael C.
Published in Blood (21.07.2016)
Published in Blood (21.07.2016)
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BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia
Kong, Weimin, Dimitri, Alexander, Wang, Wenliang, Jung, In-Young, Ott, Christopher J, Fasolino, Maria, Wang, Yan, Kulikovskaya, Irina, Gupta, Minnal, Yoder, Todd, DeNizio, Jamie E, Everett, John K, Williams, Erik F, Xu, Jun, Scholler, John, Reich, Tyler J, Bhoj, Vijay G, Haines, Kathleen M, Maus, Marcela V, Melenhorst, J. Joseph, Young, Regina M, Jadlowsky, Julie K, Marcucci, Katherine T, Bradner, James E, Levine, Bruce L, Porter, David L, Bushman, Frederic D, Kohli, Rahul M, June, Carl H, Davis, Megan M, Lacey, Simon F, Vahedi, Golnaz, Fraietta, Joseph A
Published in The Journal of clinical investigation (15.08.2021)
Published in The Journal of clinical investigation (15.08.2021)
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Enhanced procoagulant activity of select hemophilia B causing factor IX variants with emicizumab
Lee, Kyumin, Chau, Julia Q., Suber, Yani B., Sternberg, Anna R., Pishko, Allyson M., George, Lindsey A., Bhoj, Vijay G., Doshi, Bhavya S., Samelson-Jones, Benjamin J.
Published in Blood (12.09.2024)
Published in Blood (12.09.2024)
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Red cell exchange for rapid leukoreduction in adults with hyperleukocytosis and leukostasis
Mack, Ethan A., Dougher, Meaghan C., Ginda, Ashley M., Cahill, Caitlin, Murter, Melissa, Schell, Kevin, Tanhehco, Yvette C., Bhoj, Vijay G., Fesnak, Andrew D., Siegel, Don L., Kambayashi, Taku, Aqui, Nicole A., O’Doherty, Una
Published in Blood (14.03.2024)
Published in Blood (14.03.2024)
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SARS-CoV-2 Spike-Specific T-Cell Responses in Patients With B-Cell Depletion Who Received Chimeric Antigen Receptor T-Cell Treatments
Parvathaneni, Kalpana, Torres-Rodriguez, Kyabeth, Meng, Wenzhao, Hwang, Wei-Ting, Frey, Noelle, Naji, Ali, Bhoj, Vijay G
Published in JAMA oncology (01.01.2022)
Published in JAMA oncology (01.01.2022)
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Absolute lymphocyte count proliferation kinetics after CAR T-cell infusion impact response and relapse
Faude, Sophia, Wei, Jane, Muralidharan, Kavitha, Xu, Xiaoming, Wertheim, Gerald, Paessler, Michele, Bhoj, Vijay G., Grupp, Stephan A., Maude, Shannon L., Rheingold, Susan R., Pillai, Vinodh
Published in Blood advances (27.04.2021)
Published in Blood advances (27.04.2021)
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