A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation
Wagner, Gregory R, Bhatt, Dhaval P, O'Connell, Thomas M, Thompson, J Will, Dubois, Laura G, Backos, Donald S, Yang, Hao, Mitchell, Grant A, Ilkayeva, Olga R, Stevens, Robert D, Grimsrud, Paul A, Hirschey, Matthew D
Published in Cell metabolism (04.04.2017)
Published in Cell metabolism (04.04.2017)
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Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell
Puray-Chavez, Maritza, LaPak, Kyle M., Schrank, Travis P., Elliott, Jennifer L., Bhatt, Dhaval P., Agajanian, Megan J., Jasuja, Ria, Lawson, Dana Q., Davis, Keanu, Rothlauf, Paul W., Liu, Zhuoming, Jo, Heejoon, Lee, Nakyung, Tenneti, Kasyap, Eschbach, Jenna E., Shema Mugisha, Christian, Cousins, Emily M., Cloer, Erica W., Vuong, Hung R., VanBlargan, Laura A., Bailey, Adam L., Gilchuk, Pavlo, Crowe, James E., Diamond, Michael S., Hayes, D. Neil, Whelan, Sean P.J., Horani, Amjad, Brody, Steven L., Goldfarb, Dennis, Major, M. Ben, Kutluay, Sebla B.
Published in Cell reports (Cambridge) (13.07.2021)
Published in Cell reports (Cambridge) (13.07.2021)
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Mechanism‐Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure–Activity Relationship, Biostructural, and Kinetic Insight
Rajabi, Nima, Auth, Marina, Troelsen, Kathrin R., Pannek, Martin, Bhatt, Dhaval P., Fontenas, Martin, Hirschey, Matthew D., Steegborn, Clemens, Madsen, Andreas S., Olsen, Christian A.
Published in Angewandte Chemie International Edition (20.11.2017)
Published in Angewandte Chemie International Edition (20.11.2017)
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Journal Article
Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria
Speck, Sarah L., Bhatt, Dhaval P., Zhang, Qiang, Adak, Sangeeta, Yin, Li, Dong, Guifang, Feng, Chu, Zhang, Wei, Ben Major, M., Wei, Xiaochao, Semenkovich, Clay F.
Published in Cell reports (Cambridge) (28.11.2023)
Published in Cell reports (Cambridge) (28.11.2023)
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Journal Article
daf-16 /FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival
Hibshman, Jonathan D, Doan, Alexander E, Moore, Brad T, Kaplan, Rebecca Ew, Hung, Anthony, Webster, Amy K, Bhatt, Dhaval P, Chitrakar, Rojin, Hirschey, Matthew D, Baugh, L Ryan
Published in eLife (24.10.2017)
Published in eLife (24.10.2017)
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A sensitive HPLC-based method to quantify adenine nucleotides in primary astrocyte cell cultures
Bhatt, Dhaval P., Chen, Xuesong, Geiger, Jonathan D., Rosenberger, Thad A.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.03.2012)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.03.2012)
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Early-life mitochondrial DNA damage results in lifelong deficits in energy production mediated by redox signaling in Caenorhabditis elegans
Hershberger, Kathleen A., Rooney, John P., Turner, Elena A., Donoghue, Lauren J., Bodhicharla, Rakesh, Maurer, Laura L., Ryde, Ian T., Kim, Jina J., Joglekar, Rashmi, Hibshman, Jonathan D., Smith, Latasha L., Bhatt, Dhaval P., Ilkayeva, Olga R., Hirschey, Matthew D., Meyer, Joel N.
Published in Redox biology (01.07.2021)
Published in Redox biology (01.07.2021)
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Journal Article
93-OR: Hepatic Acyl-Protein Thioesterases Prevent Insulin Resistance
SPECK, SARAH L., ZHANG, QIANG, BHATT, DHAVAL P., ADAK, SANGEETA, DONG, GUIFANG, WEI, XIAOCHAO, SEMENKOVICH, CLAY F.
Published in Diabetes (New York, N.Y.) (20.06.2023)
Published in Diabetes (New York, N.Y.) (20.06.2023)
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Proximity proteomic analysis of the NRF family reveals the Parkinson's disease protein ZNF746/PARIS as a co-complexed repressor of NRF2
LaPak, Kyle M, Saeidi, Soma, Bok, Ilah, Wamsley, Nathan T, Plutzer, Isaac B, Bhatt, Dhaval P, Luo, Jingqin, Ashrafi, Ghazaleh, Ben Major, M
Published in Science signaling (12.12.2023)
Published in Science signaling (12.12.2023)
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Protein proximity networks and functional evaluation of the casein kinase 1 gamma family reveal unique roles for CK1γ3 in WNT signaling
Agajanian, Megan J., Potjewyd, Frances M., Bowman, Brittany M., Solomon, Smaranda, LaPak, Kyle M., Bhatt, Dhaval P., Smith, Jeffery L., Goldfarb, Dennis, Axtman, Alison D., Major, Michael B.
Published in The Journal of biological chemistry (01.06.2022)
Published in The Journal of biological chemistry (01.06.2022)
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Multiple metabolic changes mediate the response of Caenorhabditis elegans to the complex I inhibitor rotenone
Gonzalez-Hunt, Claudia P., Luz, Anthony L., Ryde, Ian T., Turner, Elena A., Ilkayeva, Olga R., Bhatt, Dhaval P., Hirschey, Matthew D., Meyer, Joel N.
Published in Toxicology (Amsterdam) (15.01.2021)
Published in Toxicology (Amsterdam) (15.01.2021)
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Journal Article
Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice
Bhatt, Dhaval P., Mills, C. Allie, Anderson, Kristin A., Henriques, Bárbara J., Lucas, Tânia G., Francisco, Sara, Liu, Juan, Ilkayeva, Olga R., Adams, Alexander E., Kulkarni, Shreyas R., Backos, Donald S., Major, Michael B., Grimsrud, Paul A., Gomes, Cláudio M., Hirschey, Matthew D.
Published in The Journal of biological chemistry (01.04.2022)
Published in The Journal of biological chemistry (01.04.2022)
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Journal Article
Nicotinamide mononucleotide requires SIRT3 to improve cardiac function and bioenergetics in a Friedreich's ataxia cardiomyopathy model
Martin, Angelical S, Abraham, Dennis M, Hershberger, Kathleen A, Bhatt, Dhaval P, Mao, Lan, Cui, Huaxia, Liu, Juan, Liu, Xiaojing, Muehlbauer, Michael J, Grimsrud, Paul A, Locasale, Jason W, Payne, R Mark, Hirschey, Matthew D
Published in JCI insight (20.07.2017)
Published in JCI insight (20.07.2017)
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Sirtuin 5 Is Regulated by the SCFCyclin F Ubiquitin Ligase and Is Involved in Cell Cycle Control
Mills, Christine A., Wang, Xianxi, Bhatt, Dhaval P., Grimsrud, Paul A., Matson, Jacob Peter, Lahiri, Debojyoti, Burke, Daniel J., Cook, Jeanette Gowen, Hirschey, Matthew D., Emanuele, Michael J.
Published in Molecular and cellular biology (25.01.2021)
Published in Molecular and cellular biology (25.01.2021)
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Journal Article
Frontispiece: Mechanism‐Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure–Activity Relationship, Biostructural, and Kinetic Insight
Rajabi, Nima, Auth, Marina, Troelsen, Kathrin R., Pannek, Martin, Bhatt, Dhaval P., Fontenas, Martin, Hirschey, Matthew D., Steegborn, Clemens, Madsen, Andreas S., Olsen, Christian A.
Published in Angewandte Chemie International Edition (20.11.2017)
Published in Angewandte Chemie International Edition (20.11.2017)
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Journal Article
Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-Like Effect in Caenorhabditis elegans
Luz, Anthony T, Godebo, Tewodros R, Bhatt, Dhaval P, Ilkayeva, Olga R, Maurer, Laura L, Hirschey, Matthew D, Meyer, Joel N
Published in Toxicological sciences (01.11.2016)
Published in Toxicological sciences (01.11.2016)
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Journal Article
Acetate supplementation modulates brain adenosine metabolizing enzymes and adenosine A₂A receptor levels in rats subjected to neuroinflammation
Smith, Mark D, Bhatt, Dhaval P, Geiger, Jonathan D, Rosenberger, Thad A
Published in Journal of neuroinflammation (04.06.2014)
Published in Journal of neuroinflammation (04.06.2014)
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