Age- and Genotype-Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate-Glucuronosyltransferases in Human Liver
Bhatt, Deepak Kumar, Mehrotra, Aanchal, Gaedigk, Andrea, Chapa, Revathi, Basit, Abdul, Zhang, Haeyoung, Choudhari, Prachi, Boberg, Mikael, Pearce, Robin E, Gaedigk, Roger, Broeckel, Ulrich, Leeder, J Steven, Prasad, Bhagwat
Published in Clinical pharmacology and therapeutics (01.01.2019)
Published in Clinical pharmacology and therapeutics (01.01.2019)
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Journal Article
The Promises of Quantitative Proteomics in Precision Medicine
Prasad, Bhagwat, Vrana, Marc, Mehrotra, Aanchal, Johnson, Katherine, Bhatt, Deepak Kumar
Published in Journal of pharmaceutical sciences (01.03.2017)
Published in Journal of pharmaceutical sciences (01.03.2017)
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Journal Article
Abundance of Phase 1 and 2 Drug-Metabolizing Enzymes in Alcoholic and Hepatitis C Cirrhotic Livers: A Quantitative Targeted Proteomics Study
Prasad, Bhagwat, Bhatt, Deepak Kumar, Johnson, Katherine, Chapa, Revathi, Chu, Xiaoyan, Salphati, Laurent, Xiao, Guangqing, Lee, Caroline, Hop, Cornelis E C A, Mathias, Anita, Lai, Yurong, Liao, Mingxiang, Humphreys, William G, Kumer, Sean C, Unadkat, Jashvant D
Published in Drug metabolism and disposition (01.07.2018)
Published in Drug metabolism and disposition (01.07.2018)
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Journal Article
Interindividual variability in hepatic expression of human sulfotransferase 2A1: Absolute quantification by LC-MS/MS proteomics and effect of ethnicity, genotype, age and gender
Ladumor, Mayurbhai Kathadbhai, Bhatt, Deepak Kumar, Singh, Saranjit, Prasad, Bhagwat
Published in Drug metabolism and pharmacokinetics (01.01.2019)
Published in Drug metabolism and pharmacokinetics (01.01.2019)
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Journal Article
Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants
Boberg, Mikael, Vrana, Marc, Mehrotra, Aanchal, Pearce, Robin E., Gaedigk, Andrea, Bhatt, Deepak Kumar, Leeder, J. Steven, Prasad, Bhagwat
Published in Drug metabolism and disposition (01.02.2017)
Published in Drug metabolism and disposition (01.02.2017)
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Journal Article
Effect of oral testosterone on the plasma steroid metabolomics in humans
Basit, Abdul, Zhang, Hay Young, Bhatt, Deepak Kumar, Amory, John K., Prasad, Bhagwat
Published in Drug metabolism and pharmacokinetics (01.01.2018)
Published in Drug metabolism and pharmacokinetics (01.01.2018)
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Journal Article
Differential effects of tannic acid on cisplatin induced nephrotoxicity in rats
Tikoo, Kulbhushan, Bhatt, Deepak Kumar, Gaikwad, Anil Bhanudas, Sharma, Vikram, Kabra, Dhiraj G.
Published in FEBS letters (15.05.2007)
Published in FEBS letters (15.05.2007)
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Journal Article
Critical Issues and Optimized Practices in Quantification of Protein Abundance Level to Determine Interindividual Variability in DMET Proteins by LC-MS/MS Proteomics
Bhatt, Deepak Kumar, Prasad, Bhagwat
Published in Clinical pharmacology and therapeutics (01.04.2018)
Published in Clinical pharmacology and therapeutics (01.04.2018)
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Journal Article
PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice
Li, Cindy Yanfei, Dempsey, Joseph L, Wang, Dongfang, Lee, SooWan, Weigel, Kris M, Fei, Qiang, Bhatt, Deepak Kumar, Prasad, Bhagwat, Raftery, Daniel, Gu, Haiwei, Cui, Julia Yue
Published in Drug metabolism and disposition (01.08.2018)
Published in Drug metabolism and disposition (01.08.2018)
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Journal Article
Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism
Ladumor, Mayur K, Bhatt, Deepak Kumar, Gaedigk, Andrea, Sharma, Sheena, Thakur, Aarzoo, Pearce, Robin E, Leeder, J Steven, Bolger, Michael B, Singh, Saranjit, Prasad, Bhagwat
Published in Drug metabolism and disposition (01.08.2019)
Published in Drug metabolism and disposition (01.08.2019)
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Journal Article
In Vivo-to-In Vitro Extrapolation of Transporter-Mediated Renal Clearance: Relative Expression Factor Versus Relative Activity Factor Approach
Kumar, Aditya R, Prasad, Bhagwat, Bhatt, Deepak Kumar, Mathialagan, Sumathy, Varma, Manthena V S, Unadkat, Jashvant D
Published in Drug metabolism and disposition (01.06.2021)
Published in Drug metabolism and disposition (01.06.2021)
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Journal Article
In Vitro–to–In Vivo Extrapolation of Transporter-Mediated Renal Clearance: Relative Expression Factor Versus Relative Activity Factor Approach
Kumar, Aditya R., Prasad, Bhagwat, Bhatt, Deepak Kumar, Mathialagan, Sumathy, Varma, Manthena V. S., Unadkat, Jashvant D.
Published in Drug metabolism and disposition (01.06.2021)
Published in Drug metabolism and disposition (01.06.2021)
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Journal Article
Nitric oxide synthase, calcitonin gene-related peptide and NK-1 receptor mechanisms are involved in GTN-induced neuronal activation
Ramachandran, Roshni, Bhatt, Deepak Kumar, Ploug, Kenneth Beri, Hay-Schmidt, Anders, Jansen-Olesen, Inger, Gupta, Saurabh, Olesen, Jes
Published in Cephalalgia (01.02.2014)
Published in Cephalalgia (01.02.2014)
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Journal Article
Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants
Boberg, Mikael, Vrana, Marc, Mehrotra, Aanchal, Pearce, Robin E, Gaedigk, Andrea, Bhatt, Deepak Kumar, Leeder, J Steven, Prasad, Bhagwat
Published in Drug metabolism and disposition (01.02.2017)
Published in Drug metabolism and disposition (01.02.2017)
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Journal Article
Integrative molecular characterisation of gallbladder cancer reveals micro-environment-associated subtypes
Nepal, Chirag, Zhu, Bin, O’Rourke, Colm J., Bhatt, Deepak Kumar, Lee, Donghyuk, Song, Lei, Wang, Difei, Van Dyke, Alison L., Choo-Wosoba, Hyoyoung, Liu, Zhiwei, Hildesheim, Allan, Goldstein, Alisa M., Dean, Michael, LaFuente-Barquero, Juan, Lawrence, Scott, Mutreja, Karun, Olanich, Mary E., Lorenzo Bermejo, Justo, Ferreccio, Catterina, Roa, Juan Carlos, Rashid, Asif, Hsing, Ann W., Gao, Yu-Tang, Chanock, Stephen J., Araya, Juan Carlos, Andersen, Jesper B., Koshiol, Jill
Published in Journal of hepatology (01.05.2021)
Published in Journal of hepatology (01.05.2021)
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Journal Article
Effect of TRPA1 activator allyl isothiocyanate (AITC) on rat dural and pial arteries
Hansted, Anna Koldbro, Bhatt, Deepak Kumar, Olesen, Jes, Jensen, Lars Jørn, Jansen-Olesen, Inger
Published in Pharmacological reports (01.08.2019)
Published in Pharmacological reports (01.08.2019)
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Journal Article
Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver
Xu, Meijuan, Bhatt, Deepak Kumar, Yeung, Catherine K, Claw, Katrina G, Chaudhry, Amarjit S, Gaedigk, Andrea, Pearce, Robin E, Broeckel, Ulrich, Gaedigk, Roger, Nickerson, Deborah A, Schuetz, Erin, Rettie, Allan E, Leeder, J Steven, Thummel, Kenneth E, Prasad, Bhagwat
Published in The Journal of pharmacology and experimental therapeutics (01.11.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2017)
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Journal Article