TKTL1 Is Activated by Promoter Hypomethylation and Contributes to Head and Neck Squamous Cell Carcinoma Carcinogenesis through Increased Aerobic Glycolysis and HIF1α Stabilization
Sun, Wenyue, Liu, Yan, Glazer, Chad A., Shao, Chunbo, Bhan, Sheetal, Demokan, Semra, Zhao, Ming, Rudek, Michelle A., Ha, Patrick K., Califano, Joseph A.
Published in Clinical cancer research (01.02.2010)
Published in Clinical cancer research (01.02.2010)
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Integrated, Genome-Wide Screening for Hypomethylated Oncogenes in Salivary Gland Adenoid Cystic Carcinoma
CHUNBO SHAO, WENYUE SUN, MOSKALUK, Christopher A, SIDRANSKY, David, CALIFANO, Joseph A, HA, Patrick K, TAN, Marietta, GLAZER, Chad A, BHAN, Sheetal, XIAOLI ZHONG, FAKHRY, Carole, SHARMA, Rajni, WESTRA, William H, HOQUE, Mohammad O
Published in Clinical cancer research (01.07.2011)
Published in Clinical cancer research (01.07.2011)
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Integrative discovery of epigenetically derepressed cancer testis antigens in NSCLC
Glazer, Chad A, Smith, Ian M, Ochs, Michael F, Begum, Shahnaz, Westra, William, Chang, Steven S, Sun, Wenyue, Bhan, Sheetal, Khan, Zubair, Ahrendt, Steven, Califano, Joseph A
Published in PloS one (04.12.2009)
Published in PloS one (04.12.2009)
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Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer
Smith, Ian M, Glazer, Chad A, Mithani, Suhail K, Ochs, Michael F, Sun, Wenyue, Bhan, Sheetal, Vostrov, Alexander, Abdullaev, Ziedulla, Lobanenkov, Victor, Gray, Andrew, Liu, Chunyan, Chang, Steven S, Ostrow, Kimberly L, Westra, William H, Begum, Shahnaz, Dhara, Mousumi, Califano, Joseph
Published in PloS one (23.03.2009)
Published in PloS one (23.03.2009)
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Dose-dependent activation of putative oncogene SBSN by BORIS
Gaykalova, Daria, Vatapalli, Rajita, Glazer, Chad A, Bhan, Sheetal, Shao, Chunbo, Sidransky, David, Ha, Patrick K, Califano, Joseph A
Published in PloS one (05.07.2012)
Published in PloS one (05.07.2012)
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MAGEA4 induces growth in normal oral keratinocytes by inhibiting growth arrest and apoptosis
BHAN, SHEETAL, CHUANG, ALICE, NEGI, SANDEEP S, GLAZER, CHAD A, CALIFANO, JOSEPH A
Published in Oncology reports (01.10.2012)
Published in Oncology reports (01.10.2012)
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Exomic Sequencing of Medullary Thyroid Cancer Reveals Dominant and Mutually Exclusive Oncogenic Mutations in RET and RAS
Agrawal, Nishant, Jiao, Yuchen, Sausen, Mark, Leary, Rebecca, Bettegowda, Chetan, Roberts, Nicholas J, Bhan, Sheetal, Ho, Allen S, Khan, Zubair, Bishop, Justin, Westra, William H, Wood, Laura D, Hruban, Ralph H, Tufano, Ralph P, Robinson, Bruce, Dralle, Henning, Toledo, Sergio P. A, Toledo, Rodrigo A, Morris, Luc G. T, Ghossein, Ronald A, Fagin, James A, Chan, Timothy A, Velculescu, Victor E, Vogelstein, Bert, Kinzler, Kenneth W, Papadopoulos, Nickolas, Nelkin, Barry D, Ball, Douglas W
Published in The journal of clinical endocrinology and metabolism (01.02.2013)
Published in The journal of clinical endocrinology and metabolism (01.02.2013)
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Trametinib with and without pazopanib has potent preclinical activity in thyroid cancer
BALL, DOUGLAS W, JIN, NING, XUE, PING, BHAN, SHEETAL, AHMED, SHABINA R, ROSEN, D. MARC, SCHAYOWITZ, ADAM, CLARK, DOUGLAS P, NELKIN, BARRY D
Published in Oncology reports (01.11.2015)
Published in Oncology reports (01.11.2015)
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BORIS Binding to the Promoters of Cancer Testis Antigens, MAGEA2, MAGEA3, and MAGEA4, Is Associated with Their Transcriptional Activation in Lung Cancer
BHAN, Sheetal, NEGI, Sandeep S, CHUNBO SHAO, GLAZER, Chad A, CHUANG, Alice, GAYKALOVA, Daria A, WENYUE SUN, SIDRANSKY, David, HA, Patrick K, CALIFANO, Joseph A
Published in Clinical cancer research (01.07.2011)
Published in Clinical cancer research (01.07.2011)
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Abstract 5001: BORIS and MageA expression correlate positively in melanoma
Bhan, Sheetal, Shao, Chunbo, Wang, Hao, Glazer, Chad, Lobanenkov, Victor, Ha, Patrick, Califano, Joseph
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Abstract 2042: Cancer-specific transcription factor BORIS has different effects on expression of its target genes via chromatin structure alterations
Gaykalova, Daria A., Glazer, Chad A., Vatapalli, Rajita, Bhan, Sheetal, Shao, Chunbo, Ha, Patrick K., Califano, Joseph A.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Abstract 4802: Cat eye syndrome chromosome region, candidate 1 (CECR1) is overexpressed and hypomethylated in salivary gland adenoid cystic carcinoma
Shao, Chunbo, Tan, Marietta, Glazer, Chad A., Bhan, Sheetal, Chang, Xiaofei, Uemura, Mamoru, Kim, Myoung S., Moskaluk, Christopher, Sidransky, David, Califano, Joseph A., Ha, Patrick K.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Abstract 4966: BORIS binding to the promoters of cancer testes antigens, MageA2 and MageA3, causes transcriptional activation of these genes in lung cancer
Bhan, Sheetal, Negi, Sandeep S., Glazer, Chad, Chuang, Alice, Sun, Wenyue, Gaykalova, Daria, Shao, Chunbo, Ha, Patrick K., Califano, Joseph A.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Abstract 2202: Integrated screening for epigenetically controlled tumor suppressor genes and oncogenes in salivary adenoid cystic carcinoma
Shao, Chunbo, Sun, Wenyue, Cope, Leslie, Bai, Weiliang, Bhan, Sheetal, Zhong, Xiaoli, Sidransky, David, Califano, Joseph A., Moskaluk, Christopher, Ha, Patrick K.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Abstract 63: TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis via increased aerobic glycolysis and HIF1-alpha stabilization
Sun, Wenyue, Liu, Yan, Glazer, Chad A., Shao, Chunbo, Bhan, Sheetal, Demokan, Semra, Zhao, Ming, Rudek, Michelle A., Ha, Patrick K., Califano, Joseph A.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization
Sun, Wenyue, Liu, Yan, Glazer, Chad A, Shao, Chunbo, Bhan, Sheetal, Demokan, Semra, Zhao, Ming, Rudek, Michelle A, Ha, Patrick K, Califano, Joseph A
Published in Clinical cancer research (01.02.2010)
Published in Clinical cancer research (01.02.2010)
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Journal Article
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis via increased aerobic glycolysis and HIF1α stabilization
Sun, Wenyue, Liu, Yan, Glazer, Chad A., Shao, Chunbo, Bhan, Sheetal, Demokan, Semra, Zhao, Ming, Rudek, Michelle A., Ha, Patrick K., Califano, Joseph A.
Published in Clinical cancer research (26.01.2010)
Published in Clinical cancer research (26.01.2010)
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