An extended APOBEC3A mutation signature in cancer
Langenbucher, Adam, Bowen, Danae, Sakhtemani, Ramin, Bournique, Elodie, Wise, Jillian F, Zou, Lee, Bhagwat, Ashok S, Buisson, Rémi, Lawrence, Michael S
Published in Nature communications (11.03.2021)
Published in Nature communications (11.03.2021)
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Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation
Hashimoto, Hideharu, Hong, Samuel, Bhagwat, Ashok S, Zhang, Xing, Cheng, Xiaodong
Published in Nucleic acids research (01.11.2012)
Published in Nucleic acids research (01.11.2012)
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Strand-biased cytosine deamination at the replication fork causes cytosine to thymine mutations in Escherichia coli
Bhagwat, Ashok S., Hao, Weilong, Townes, Jesse P., Lee, Heewook, Tang, Haixu, Foster, Patricia L.
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2016)
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The Novel β-Lactam Enhancer Zidebactam Augments the In Vivo Pharmacodynamic Activity of Cefepime in a Neutropenic Mouse Lung Acinetobacter baumannii Infection Model
Bhagwat, S S, Periasamy, H, Takalkar, S S, Palwe, S R, Khande, H N, Patel, M V
Published in Antimicrobial agents and chemotherapy (01.04.2019)
Published in Antimicrobial agents and chemotherapy (01.04.2019)
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Distinguishing preferences of human APOBEC3A and APOBEC3B for cytosines in hairpin loops, and reflection of these preferences in APOBEC-signature cancer genome mutations
Butt, Yasha, Sakhtemani, Ramin, Mohamad-Ramshan, Rukshana, Lawrence, Michael S, Bhagwat, Ashok S
Published in Nature communications (18.03.2024)
Published in Nature communications (18.03.2024)
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Human activation-induced deaminase lacks strong replicative strand bias or preference for cytosines in hairpin loops
Sakhtemani, Ramin, Perera, Madusha L W, Hübschmann, Daniel, Siebert, Reiner, Lawrence, Michael S, Bhagwat, Ashok S
Published in Nucleic acids research (20.05.2022)
Published in Nucleic acids research (20.05.2022)
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Formulation and Development of Transferrin Targeted Solid Lipid Nanoparticles for Breast Cancer Therapy
Bhagwat, Geeta S, Athawale, Rajani B, Gude, Rajeev P, Md, Shadab, Alhakamy, Nabil A, Fahmy, Usama A, Kesharwani, Prashant
Published in Frontiers in pharmacology (27.11.2020)
Published in Frontiers in pharmacology (27.11.2020)
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AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML)
Zarrinkar, Patrick P., Gunawardane, Ruwanthi N., Cramer, Merryl D., Gardner, Michael F., Brigham, Daniel, Belli, Barbara, Karaman, Mazen W., Pratz, Keith W., Pallares, Gabriel, Chao, Qi, Sprankle, Kelly G., Patel, Hitesh K., Levis, Mark, Armstrong, Robert C., James, Joyce, Bhagwat, Shripad S.
Published in Blood (01.10.2009)
Published in Blood (01.10.2009)
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SP600125, An Anthrapyrazolone Inhibitor of Jun N-Terminal Kinase
Bennett, Brydon L., Sasaki, Dennis T., Murray, Brion W., O'Leary, Eoin C., Sakata, Steve T., Xu, Weiming, Leisten, Jim C., Motiwala, Aparna, Pierce, Steve, Satoh, Yoshitaka, Bhagwat, Shripad S., Manning, Anthony M., Anderson, David W.
Published in Proceedings of the National Academy of Sciences - PNAS (20.11.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (20.11.2001)
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A Tumor-Promoting Phorbol Ester Causes a Large Increase in APOBEC3A Expression and a Moderate Increase in APOBEC3B Expression in a Normal Human Keratinocyte Cell Line without Increasing Genomic Uracils
Siriwardena, Sachini U., Perera, Madusha L. W., Senevirathne, Vimukthi, Stewart, Jessica, Bhagwat, Ashok S.
Published in Molecular and cellular biology (01.01.2019)
Published in Molecular and cellular biology (01.01.2019)
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Effect of sine-Gaussian glitches on searches for binary coalescence
Canton, T Dal, Bhagwat, S, Dhurandhar, S V, Lundgren, A
Published in Classical and quantum gravity (07.01.2014)
Published in Classical and quantum gravity (07.01.2014)
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RAF inhibitor LY3009120 sensitizes RAS or BRAF mutant cancer to CDK4/6 inhibition by abemaciclib via superior inhibition of phospho-RB and suppression of cyclin D1
Chen, S-H, Gong, X, Zhang, Y, Van Horn, R D, Yin, T, Huber, L, Burke, T F, Manro, J, Iversen, P W, Wu, W, Bhagwat, S V, Beckmann, R P, Tiu, R V, Buchanan, S G, Peng, S-B
Published in Oncogene (08.02.2018)
Published in Oncogene (08.02.2018)
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An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis
Tran, Vinh G, Mishra, Somesh, Bhagwat, Sarang S, Shafaei, Saman, Shen, Yihui, Allen, Jayne L, Crosly, Benjamin A, Tan, Shih-I, Fatma, Zia, Rabinowitz, Joshua D, Guest, Jeremy S, Singh, Vijay, Zhao, Huimin
Published in Nature communications (03.10.2023)
Published in Nature communications (03.10.2023)
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