A translational pharmacokinetic/pharmacodynamic model to characterize bacterial kill in the presence of imipenem-relebactam
Bhagunde, Pratik, Zhang, Zufei, Racine, Fred, Carr, Donna, Wu, Jin, Young, Katherine, Rizk, Matthew L.
Published in International journal of infectious diseases (01.12.2019)
Published in International journal of infectious diseases (01.12.2019)
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Journal Article
Exploring the Pharmacokinetic/Pharmacodynamic Relationship of Relebactam (MK-7655) in Combination with Imipenem in a Hollow-Fiber Infection Model
Wu, Jin, Racine, Fred, Wismer, Michael K, Young, Katherine, Carr, Donna M, Xiao, Jing C, Katwaru, Ravi, Si, Qian, Harradine, Paul, Motyl, Mary, Bhagunde, Pratik R, Rizk, Matthew L
Published in Antimicrobial agents and chemotherapy (01.05.2018)
Published in Antimicrobial agents and chemotherapy (01.05.2018)
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Journal Article
Population Pharmacokinetic Analysis for Imipenem–Relebactam in Healthy Volunteers and Patients With Bacterial Infections
Bhagunde, Pratik, Patel, Parul, Lala, Mallika, Watson, Kenny, Copalu, William, Xu, Ming, Kulkarni, Pooja, Young, Katherine, Rizk, Matthew L.
Published in CPT: pharmacometrics and systems pharmacology (01.10.2019)
Published in CPT: pharmacometrics and systems pharmacology (01.10.2019)
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Journal Article
Novel Modeling Framework To Guide Design of Optimal Dosing Strategies for β-Lactamase Inhibitors
BHAGUNDE, Pratik, CHANG, Kai-Tai, HIRSCH, Elizabeth B, LEDESMA, Kimberly R, NIKOLAOU, Michael, TAM, Vincent H
Published in Antimicrobial Agents and Chemotherapy (01.05.2012)
Published in Antimicrobial Agents and Chemotherapy (01.05.2012)
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Journal Article
Discovery of Efficacious Pseudomonas aeruginosa-Targeted Siderophore-Conjugated Monocarbams by Application of a Semi-mechanistic Pharmacokinetic/Pharmacodynamic Model
Murphy-Benenato, Kerry E, Bhagunde, Pratik R, Chen, April, Davis, Hajnalka E, Durand-Réville, Thomas F, Ehmann, David E, Galullo, Vincent, Harris, Jennifer J, Hatoum-Mokdad, Holia, Jahić, Haris, Kim, Aryun, Manjunatha, M. R, Manyak, Erika L, Mueller, John, Patey, Sara, Quiroga, Olga, Rooney, Michael, Sha, Li, Shapiro, Adam B, Sylvester, Mark, Tan, Beesan, Tsai, Andy S, Uria-Nickelsen, Maria, Wu, Ye, Zambrowski, Mark, Zhao, Shannon X
Published in Journal of medicinal chemistry (12.03.2015)
Published in Journal of medicinal chemistry (12.03.2015)
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Journal Article
Mathematical Modeling To Characterize the Inoculum Effect
BHAGUNDE, Pratik, CHANG, Kai-Tai, SINGH, Renu, SINGH, Vandana, GAREY, Kevin W, NIKOLAOU, Michael, TAM, Vincent H
Published in Antimicrobial Agents and Chemotherapy (01.11.2010)
Published in Antimicrobial Agents and Chemotherapy (01.11.2010)
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Journal Article
A Population Pharmacokinetic (PopPK) Model to Characterize Efanesoctocog Alfa (BIVV001) Factor VIII (FVIII) Activity Levels in Patients with Severe Hemophilia A
Bhagunde, Pratik, Lu, Qiang, Demissie, Marek, Willemze, Annemieke, Katragadda, Suresh
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Fitusiran Population Pharmacokinetic and Pharmacodynamic Modeling Utilizing Phase 3 Clinical Trial Data to Confirm Doses Tested in Phase 3 Trials to Support an Antithrombin-Based Dose Regimen
Madrasi, Kumpal, Bhagunde, Pratik, Iqbal, Sajida, Puurunen, Marja, Demissie, Marek, Andersson, Shauna, Macha, Sreeraj, Ahamadi, Malidi
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Development of a Quantitative Systems Pharmacology Model to Explore Hemostatic Equivalency of Antithrombin Lowering
Kaddi, Chanchala, Tao, Mengdi, Leiser, Randolph, Salvador, Ane, Kattula, Sravya, Bhagunde, Pratik, Cano Garcia, Viridiana, Chhabra, Ekta Seth, Zaph, Susana
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Pharmacokinetics, Safety, and Tolerability of Single and Multiple Doses of Relebactam, a β-Lactamase Inhibitor, in Combination with Imipenem and Cilastatin in Healthy Participants
Rhee, Elizabeth G, Rizk, Matthew L, Calder, Nicole, Nefliu, Marcela, Warrington, Steven J, Schwartz, Michael S, Mangin, Eric, Boundy, Keith, Bhagunde, Pratik, Colon-Gonzalez, Francheska, Jumes, Patricia, Liu, Yang, Butterton, Joan R
Published in Antimicrobial agents and chemotherapy (01.09.2018)
Published in Antimicrobial agents and chemotherapy (01.09.2018)
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Journal Article
피투시란을 이용한 혈우병의 치료
ANDERSSON SHAUNA, POLOSKEY STACEY, BHAGUNDE PRATIK R, MEI BAISONG, CUI YUE, IQBAL SAJIDA
Year of Publication 08.08.2023
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Year of Publication 08.08.2023
Patent
Impact of renal impairment and human organic anion transporter inhibition on pharmacokinetics, safety and tolerability of relebactam combined with imipenem and cilastatin
Bhagunde, Pratik, Colon‐Gonzalez, Francheska, Liu, Yang, Wu, Jin, Xu, Shiyao Sherrie, Garrett, Graigory, Jumes, Patricia, Lasseter, Kenneth, Marbury, Thomas, Rizk, Matthew L., Lala, Mallika, Rhee, Elizabeth G., Butterton, Joan R., Boundy, Keith
Published in British journal of clinical pharmacology (01.05.2020)
Published in British journal of clinical pharmacology (01.05.2020)
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Journal Article
Pharmacokinetics of elbasvir and grazoprevir in subjects with end-stage renal disease or severe renal impairment
Caro, Luzelena, Wenning, Larissa, Feng, Hwa-Ping, Guo, Zifang, Du, Lihong, Bhagunde, Pratik, Fandozzi, Christine, Panebianco, Deborah, Marshall, William L., Butterton, Joan R., Iwamoto, Marian, Yeh, Wendy W.
Published in European journal of clinical pharmacology (01.05.2019)
Published in European journal of clinical pharmacology (01.05.2019)
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Journal Article
Erratum for Rhee et al., "Pharmacokinetics, Safety, and Tolerability of Single and Multiple Doses of Relebactam, a β-Lactamase Inhibitor, in Combination with Imipenem and Cilastatin in Healthy Participants"
Rhee, Elizabeth G, Rizk, Matthew L, Calder, Nicole, Nefliu, Marcela, Warrington, Steven J, Schwartz, Michael S, Mangin, Eric, Boundy, Keith, Bhagunde, Pratik, Colon-Gonzalez, Francheska, Jumes, Patricia, Liu, Yang, Butterton, Joan R
Published in Antimicrobial agents and chemotherapy (01.12.2018)
Published in Antimicrobial agents and chemotherapy (01.12.2018)
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Journal Article
Thorough QTc Study of a Single Supratherapeutic Dose of Relebactam in Healthy Participants
Boundy, Keith, Liu, Yang, Bhagunde, Pratik, O'Reilly, Terry E., Colon‐Gonzalez, Francheska, Friedman, Evan J., Lala, Mallika, Rhee, Elizabeth G., Rizk, Matthew L.
Published in Clinical pharmacology in drug development (01.05.2020)
Published in Clinical pharmacology in drug development (01.05.2020)
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Journal Article
Novel Modeling Framework To Guide Design of Optimal Dosing Strategies for ?-Lactamase Inhibitors
Bhagunde, Pratik, Chang, Kai-Tai, Hirsch, Elizabeth B, Ledesma, Kimberly R, Nikolaou, Michael, Tam, Vincent H
Published in Antimicrobial agents and chemotherapy (01.05.2012)
Published in Antimicrobial agents and chemotherapy (01.05.2012)
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Journal Article