Acetyl‐CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents
Goedeke, Leigh, Bates, Jamie, Vatner, Daniel F., Perry, Rachel J., Wang, Ting, Ramirez, Ricardo, Li, Li, Ellis, Matthew W., Zhang, Dongyan, Wong, Kari E., Beysen, Carine, Cline, Gary W., Ray, Adrian S., Shulman, Gerald I.
Published in Hepatology (Baltimore, Md.) (01.12.2018)
Published in Hepatology (Baltimore, Md.) (01.12.2018)
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Acetyl‐coenzyme A carboxylase inhibition reduces de novo lipogenesis in overweight male subjects: A randomized, double‐blind, crossover study
Stiede, Kathryn, Miao, Wenyan, Blanchette, Heather S., Beysen, Carine, Harriman, Geraldine, Harwood, H. James, Kelley, Heather, Kapeller, Rosana, Schmalbach, Tess, Westlin, William F.
Published in Hepatology (Baltimore, Md.) (01.08.2017)
Published in Hepatology (Baltimore, Md.) (01.08.2017)
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Journal Article
Insulin and glucose metabolism with olanzapine and a combination of olanzapine and samidorphan: exploratory phase 1 results in healthy volunteers
Toledo, Frederico G S, Martin, William F, Morrow, Linda, Beysen, Carine, Bajorunas, Daiva, Jiang, Ying, Silverman, Bernard L, McDonnell, David, Namchuk, Mark N, Newcomer, John W, Graham, Christine
Published in Neuropsychopharmacology (New York, N.Y.) (01.02.2022)
Published in Neuropsychopharmacology (New York, N.Y.) (01.02.2022)
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Journal Article
MicroRNA-29 Fine-tunes the Expression of Key FOXA2-Activated Lipid Metabolism Genes and Is Dysregulated in Animal Models of Insulin Resistance and Diabetes
KURTZ, C. Lisa, PECK, Bailey C. E, BIDDINGER, Sudha B, VICKERS, Kasey C, SETHUPATHY, Praveen, FANNIN, Emily E, BEYSEN, Carine, JI MIAO, LANDSTREET, Stuart R, SHENGLI DING, TURAGA, Vandana, LUND, P. Kay, TURNER, Scott
Published in Diabetes (New York, N.Y.) (01.09.2014)
Published in Diabetes (New York, N.Y.) (01.09.2014)
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Journal Article
Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion
Sedgeman, Leslie R., Beysen, Carine, Ramirez Solano, Marisol A., Michell, Danielle L., Sheng, Quanhu, Zhao, Shilin, Turner, Scott, Linton, MacRae F., Vickers, Kasey C.
Published in Scientific reports (07.03.2019)
Published in Scientific reports (07.03.2019)
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Journal Article
Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis[S]
Pickens, Michael K., Yan, Jim S., Ng, Raymond K., Ogata, Hisanobu, Grenert, James P., Beysen, Carine, Turner, Scott M., Maher, Jacquelyn J.
Published in Journal of lipid research (01.10.2009)
Published in Journal of lipid research (01.10.2009)
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Uncovering a Predictive Molecular Signature for the Onset of NASH-Related Fibrosis in a Translational NASH Mouse Model
van Koppen, Arianne, Verschuren, Lars, van den Hoek, Anita M, Verheij, Joanne, Morrison, Martine C, Li, Kelvin, Nagabukuro, Hiroshi, Costessi, Adalberto, Caspers, Martien P.M, van den Broek, Tim J, Sagartz, John, Kluft, Cornelis, Beysen, Carine, Emson, Claire, van Gool, Alain J, Goldschmeding, Roel, Stoop, Reinout, Bobeldijk-Pastorova, Ivana, Turner, Scott M, Hanauer, Guido, Hanemaaijer, Roeland
Published in Cellular and molecular gastroenterology and hepatology (01.01.2018)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2018)
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A pilot study of the effects of pioglitazone and rosiglitazone on de novo lipogenesis in type 2 diabetes
Beysen, Carine, Murphy, Elizabeth J., Nagaraja, Hirisadarahally, Decaris, Martin, Riiff, Timothy, Fong, Alex, Hellerstein, Marc K., Boyle, Patrick J.
Published in Journal of lipid research (01.12.2008)
Published in Journal of lipid research (01.12.2008)
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Journal Article
Whole-Body Glycolysis Measured by the Deuterated-Glucose Disposal Test Correlates Highly With Insulin Resistance In Vivo
Beysen, Carine, Murphy, Elizabeth J, McLaughlin, Tracey, Riiff, Timothy, Lamendola, Cindy, Turner, Holly C, Awada, Mohamad, Turner, Scott M, Reaven, Gerald, Hellerstein, Marc K
Published in Diabetes care (01.05.2007)
Published in Diabetes care (01.05.2007)
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Journal Article
low α-linolenic intake during early life increases adiposity in the adult guinea pig
Pouteau, Etienne, Aprikian, Olivier, Grenot, Catherine, Reynaud, Denis, Pace-Asciak, Cecil, Cuilleron, Claude Yves, Castaneda-Gutierrez, Euridice, Moulin, Julie, Pescia, Gregory, Beysen, Carine, Turner, Scott, Mace, Katherine
Published in Nutrition & metabolism (29.01.2010)
Published in Nutrition & metabolism (29.01.2010)
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Journal Article
Sotagliflozin Decreases Postprandial Glucose and Insulin Concentrations by Delaying Intestinal Glucose Absorption
Powell, David R, Zambrowicz, Brian, Morrow, Linda, Beysen, Carine, Hompesch, Marcus, Turner, Scott, Hellerstein, Marc, Banks, Phillip, Strumph, Paul, Lapuerta, Pablo
Published in The journal of clinical endocrinology and metabolism (01.04.2020)
Published in The journal of clinical endocrinology and metabolism (01.04.2020)
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Journal Article
Potential Mechanisms Leading to the Abnormal Lipid Profile in Patients With Rheumatoid Arthritis Versus Healthy Volunteers and Reversal by Tofacitinib
Charles‐Schoeman, Christina, Fleischmann, Roy, Davignon, Jean, Schwartz, Howard, Turner, Scott M., Beysen, Carine, Milad, Mark, Hellerstein, Marc K., Luo, Zhen, Kaplan, Irina V., Riese, Richard, Zuckerman, Andrea, McInnes, Iain B.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2015)
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Journal Article
Inhibition of fatty acid synthase with FT‐4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with non‐alcoholic fatty liver disease: Results from two early‐phase randomized trials
Beysen, Carine, Schroeder, Patricia, Wu, Eric, Brevard, Julie, Ribadeneira, Maria, Lu, Wei, Dole, Kiran, O'Reilly, Terry, Morrow, Linda, Hompesch, Marcus, Hellerstein, Marc K., Li, Kelvin, Johansson, Lars, Kelly, Patrick F.
Published in Diabetes, obesity & metabolism (01.03.2021)
Published in Diabetes, obesity & metabolism (01.03.2021)
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Journal Article
Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood
Decaris, Martin L., Li, Kelvin W., Emson, Claire L., Gatmaitan, Michelle, Liu, Shanshan, Wang, Yenny, Nyangau, Edna, Colangelo, Marc, Angel, Thomas E., Beysen, Carine, Cui, Jeffrey, Hernandez, Carolyn, Lazaro, Len, Brenner, David A., Turner, Scott M., Hellerstein, Marc K., Loomba, Rohit
Published in Hepatology (Baltimore, Md.) (01.01.2017)
Published in Hepatology (Baltimore, Md.) (01.01.2017)
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Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans
Stanhope, Kimber L, Schwarz, Jean Marc, Keim, Nancy L, Griffen, Steven C, Bremer, Andrew A, Graham, James L, Hatcher, Bonnie, Cox, Chad L, Dyachenko, Artem, Zhang, Wei, McGahan, John P, Seibert, Anthony, Krauss, Ronald M, Chiu, Sally, Schaefer, Ernst J, Ai, Masumi, Otokozawa, Seiko, Nakajima, Katsuyuki, Nakano, Takamitsu, Beysen, Carine, Hellerstein, Marc K, Berglund, Lars, Havel, Peter J
Published in The Journal of clinical investigation (01.05.2009)
Published in The Journal of clinical investigation (01.05.2009)
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Journal Article
Dietary sugar restriction reduces hepatic de novo lipogenesis in adolescent boys with fatty liver disease
Cohen, Catherine C, Li, Kelvin W, Alazraki, Adina L, Beysen, Carine, Carrier, Carissa A, Cleeton, Rebecca L, Dandan, Mohamad, Figueroa, Janet, Knight-Scott, Jack, Knott, Cynthia J, Newton, Kimberly P, Nyangau, Edna M, Sirlin, Claude B, Ugalde-Nicalo, Patricia A, Welsh, Jean A, Hellerstein, Marc K, Schwimmer, Jeffrey B, Vos, Miriam B
Published in The Journal of clinical investigation (15.12.2021)
Published in The Journal of clinical investigation (15.12.2021)
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Journal Article
107-LB: Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK-1092 in Healthy Subjects (HS)
MORROW, LINDA, GRIMM, MICHAEL, BEYSEN, CARINE, WALFORD, GEOFFREY, DUNCAN, KELLY, MITRA, PRANAB K., VADDADY, PAVAN, HOMPESCH, MARCUS
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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Journal Article
106-LB: Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK-1092 in Subjects with T1DM and T2DM
MORROW, LINDA, GRIMM, MICHAEL, BEYSEN, CARINE, WALFORD, GEOFFREY, DUNCAN, KELLY, MITRA, PRANAB K., VADDADY, PAVAN, HOMPESCH, MARCUS
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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Journal Article
Dose-dependent quantitative effects of acute fructose administration on hepatic de novo lipogenesis in healthy humans
Beysen, Carine, Ruddy, Marcella, Stoch, Aubrey, Mixson, Lori, Rosko, Kimberly, Riiff, Timothy, Turner, Scott M, Hellerstein, Marc K, Murphy, Elizabeth J
Published in American journal of physiology: endocrinology and metabolism (01.07.2018)
Published in American journal of physiology: endocrinology and metabolism (01.07.2018)
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