practical approach for exploration and modeling of the design space of a bacterial vaccine cultivation process
Streefland, M, Van Herpen, P.F.G, Van de Waterbeemd, B, Van der Pol, L.A, Beuvery, E.C, Tramper, J, Martens, D.E, Toft, M
Published in Biotechnology and bioengineering (15.10.2009)
Published in Biotechnology and bioengineering (15.10.2009)
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Journal Article
Modeling Neisseria meningitidis metabolism: from genome to metabolic fluxes
Baart, Gino J E, Zomer, Bert, de Haan, Alex, van der Pol, Leo A, Beuvery, E Coen, Tramper, Johannes, Martens, Dirk E
Published in Genome Biology (06.07.2007)
Published in Genome Biology (06.07.2007)
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Journal Article
Gene-expression-based quality scores indicate optimal harvest point in Bordetella pertussis cultivation for vaccine production
van de Waterbeemd, Bas, Streefland, Mathieu, Pennings, Jeroen, van der Pol, Leo, Beuvery, Coen, Tramper, Johannes, Martens, Dirk
Published in Biotechnology and bioengineering (01.08.2009)
Published in Biotechnology and bioengineering (01.08.2009)
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Journal Article
Modeling Neisseria meningitidis B metabolism at different specific growth rates
Baart, Gino J.E, Willemsen, Marieke, Khatami, Elnaz, de Haan, Alex, Zomer, Bert, Beuvery, E. Coen, Tramper, Johannes, Martens, Dirk E
Published in Biotechnology and bioengineering (01.12.2008)
Published in Biotechnology and bioengineering (01.12.2008)
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Journal Article
Death rate in a small air-lift loop reactor of vero cells grown on solid microcarriers and in macroporous microcarriers
MARTENS, D. E, NOLLEN, E. A. A, HARDEVELD, M, VAN DER VELDEN-DE GROOT, C. A. M, DE GOOIJER, C. D, BEUVERY, E. C, TRAMPER, J
Published in Cytotechnology (Dordrecht) (1997)
Published in Cytotechnology (Dordrecht) (1997)
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Journal Article
Improving the cellular pertussis vaccine: Increased potency and consistency
Thalen, Marcel, van der Ark, Arno, van den IJssel, Jan, van Straaten, Ineke, Jansen, Dennis, Beuvery, Coen, Martens, Dirk, Tramper, Johannes
Published in Vaccine (30.01.2008)
Published in Vaccine (30.01.2008)
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Journal Article
PAT for vaccines: The first stage of PAT implementation for development of a well-defined whole-cell vaccine against whooping cough disease
Streefland, Mathieu, van de Waterbeemd, Bas, Happé, Hester, van der Pol, Leo A, Beuvery, E. Coen, Tramper, Johannes, Martens, Dirk E
Published in Vaccine (20.04.2007)
Published in Vaccine (20.04.2007)
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Journal Article
Conference Proceeding
Expression of phosphofructokinase in Neisseria meningitidis
Baart, Gino J. E, Langenhof, Marc, van de Waterbeemd, Bas, Hamstra, Hendrik-Jan, Zomer, Bert, van der Pol, Leo A, Beuvery, E. C, Tramper, Johannes, Martens, Dirk E
Published in Microbiology (Society for General Microbiology) (01.02.2010)
Published in Microbiology (Society for General Microbiology) (01.02.2010)
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Journal Article
Scale-up for bulk production of vaccine against meningococcal disease
Baart, Gino J.E, de Jong, Govert, Philippi, Marvin, Riet, Klaas van’t, van der Pol, Leo A, Beuvery, E. Coen, Tramper, Johannes, Martens, Dirk E
Published in Vaccine (21.08.2007)
Published in Vaccine (21.08.2007)
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Journal Article
Evaluation of a critical process parameter: Oxygen limitation during cultivation has a fully reversible effect on gene expression of Bordetella pertussis
Streefland, Mathieu, van de Waterbeemd, Bas, Kint, Joeri, van der Pol, Leo A, Beuvery, E. Coen, Tramper, Johannes, Martens, Dirk E
Published in Biotechnology and bioengineering (2009)
Published in Biotechnology and bioengineering (2009)
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Journal Article
Effect of relevant culture parameters on Pertussis Toxin expression by Bordetella pertussis
Thalen, Marcel, Venema, Marian, van den IJssel, Jan, Berwald, Luc, Beuvery, Coen, Martens, Dirk, Tramper, Johannes
Published in Biologicals (01.09.2006)
Published in Biologicals (01.09.2006)
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Journal Article
Fed-batch cultivation of Bordetella pertussis: Metabolism and Pertussis Toxin production
Thalen, Marcel, Venema, Marian, Dekker, Anita, Berwald, Luc, van den IJssel, Jan, Zomer, Bert, Beuvery, Coen, Martens, Dirk, Tramper, Johannes
Published in Biologicals (01.12.2006)
Published in Biologicals (01.12.2006)
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Journal Article
Dual-substrate utilization by Bordetella pertussis
NEELEMAN, R, JOERINK, M, BEUVERY, C, VAN BOXTEL, T
Published in Applied microbiology and biotechnology (01.11.2001)
Published in Applied microbiology and biotechnology (01.11.2001)
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Journal Article
Manufacturing Vaccines: An Illustration of Using PAT Tools for Controlling the Cultivation of Bordetella pertussis
van Sprang, Eric N. M., Streefland, Mathieu, Ramaker, Henk-Jan, van der Pol, Leo A., Beuvery, E. Coen, Smilde, Age. K.
Published in Quality engineering (29.10.2007)
Published in Quality engineering (29.10.2007)
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Journal Article
Determination of amino acids using 0-phthalaldehyde-2-mercaptoethanol derivation. Effect of reaction conditions
Dorresteijn, R.C, Berwald, L.G, Zomer, G, Gooijer, C.D., de, Wieten, G, Beuvery, E.C
Published in Journal of Chromatography. A, Including electrophoresis and other separation methods (1996)
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Published in Journal of Chromatography. A, Including electrophoresis and other separation methods (1996)
Journal Article
Comparison of four bifunctional reagents for coupling peptides to proteins and the effect of the three moieties on the immunogenicity of the conjugates
Peeters, J M, Hazendonk, T G, Beuvery, E C, Tesser, G I
Published in Journal of immunological methods (02.06.1989)
Published in Journal of immunological methods (02.06.1989)
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Effect of dilution rate on growth, productivity, cell cycle and size, and shear sensitivity of a hybridoma cell in a continuous culture
Martens, D E, de Gooijer, C D, van der Velden-de Groot, C A, Beuvery, E C, Tramper, J
Published in Biotechnology and bioengineering (20.02.1993)
Published in Biotechnology and bioengineering (20.02.1993)
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