Barriers and opportunities for gemcitabine in pancreatic cancer therapy
Beutel, Alica K, Halbrook, Christopher J
Published in American Journal of Physiology: Cell Physiology (01.02.2023)
Published in American Journal of Physiology: Cell Physiology (01.02.2023)
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Journal Article
Pancreatic cancer-derived organoids – a disease modeling tool to predict drug response
Frappart, Pierre-Olivier, Walter, Karolin, Gout, Johann, Beutel, Alica K, Morawe, Mareen, Arnold, Frank, Breunig, Markus, Barth, Thomas FE, Marienfeld, Ralf, Schulte, Lucas, Ettrich, Thomas, Hackert, Thilo, Svinarenko, Michael, Rösler, Reinhild, Wiese, Sebastian, Wiese, Heike, Perkhofer, Lukas, Müller, Martin, Lechel, André, Sainz, Bruno, Hermann, Patrick C, Seufferlein, Thomas, Kleger, Alexander
Published in United European gastroenterology journal (01.06.2020)
Published in United European gastroenterology journal (01.06.2020)
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Journal Article
A Prospective Feasibility Trial to Challenge Patient–Derived Pancreatic Cancer Organoids in Predicting Treatment Response
Beutel, Alica K., Schütte, Lena, Scheible, Jeanette, Roger, Elodie, Müller, Martin, Perkhofer, Lukas, Kestler, Annika M. T. U., Kraus, Johann M., Kestler, Hans A., Barth, Thomas F. E., Lemke, Johannes, Kornmann, Marko, Ettrich, Thomas J., Gout, Johann, Seufferlein, Thomas, Kleger, Alexander
Published in Cancers (21.05.2021)
Published in Cancers (21.05.2021)
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Journal Article
Maintenance Therapy for ATM-Deficient Pancreatic Cancer by Multiple DNA Damage Response Interferences after Platinum-Based Chemotherapy
Roger, Elodie, Gout, Johann, Arnold, Frank, Beutel, Alica K, Müller, Martin, Abaei, Alireza, Barth, Thomas F E, Rasche, Volker, Seufferlein, Thomas, Perkhofer, Lukas, Kleger, Alexander
Published in Cells (Basel, Switzerland) (16.09.2020)
Published in Cells (Basel, Switzerland) (16.09.2020)
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Targeting DNA Damage Repair Mechanisms in Pancreas Cancer
Perkhofer, Lukas, Golan, Talia, Cuyle, Pieter-Jan, Matysiak-Budnik, Tamara, Van Laethem, Jean-Luc, Macarulla, Teresa, Cauchin, Estelle, Kleger, Alexander, Beutel, Alica K, Gout, Johann, Stenzinger, Albrecht, Van Cutsem, Eric, Bellmunt, Joaquim, Hammel, Pascal, O'Reilly, Eileen M, Seufferlein, Thomas
Published in Cancers (24.08.2021)
Published in Cancers (24.08.2021)
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Conference Proceeding
Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells
Halbrook, Christopher J, Thurston, Galloway, Boyer, Seth, Anaraki, Cecily, Jiménez, Jennifer A, McCarthy, Amy, Steele, Nina G, Kerk, Samuel A, Hong, Hanna S, Lin, Lin, Law, Fiona V, Felton, Catherine, Scipioni, Lorenzo, Sajjakulnukit, Peter, Andren, Anthony, Beutel, Alica K, Singh, Rima, Nelson, Barbara S, Van Den Bergh, Fran, Krall, Abigail S, Mullen, Peter J, Zhang, Li, Batra, Sandeep, Morton, Jennifer P, Stanger, Ben Z, Christofk, Heather R, Digman, Michelle A, Beard, Daniel A, Viale, Andrea, Zhang, Ji, Crawford, Howard C, Pasca di Magliano, Marina, Jorgensen, Claus, Lyssiotis, Costas A
Published in Nature cancer (01.11.2022)
Published in Nature cancer (01.11.2022)
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Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration
Arnold, Frank, Mahaddalkar, Pallavi U, Kraus, Johann M., Zhong, Xiaowei, Bergmann, Wendy, Srinivasan, Dharini, Gout, Johann, Roger, Elodie, Beutel, Alica K., Zizer, Eugen, Tharehalli, Umesh, Daiss, Nora, Russell, Ronan, Perkhofer, Lukas, Oellinger, Rupert, Lin, Qiong, Azoitei, Ninel, Weiss, Frank‐Ulrich, Lerch, Markus M., Liebau, Stefan, Katz, Sarah‐Fee, Lechel, André, Rad, Roland, Seufferlein, Thomas, Kestler, Hans A., Ott, Michael, Sharma, Amar Deep, Hermann, Patrick C., Kleger, Alexander
Published in Advanced science (01.07.2021)
Published in Advanced science (01.07.2021)
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Cabozantinib in Advanced Hepatocellular Carcinoma: Efficacy and Safety Data from an International Multicenter Real-Life Cohort
Finkelmeier, Fabian, Scheiner, Bernhard, Leyh, Catherine, Best, Jan, Fründt, Thorben Wilhelm, Czauderna, Carolin, Beutel, Alica, Bettinger, Dominik, Weiß, Johannes, Meischl, Tobias, Kütting, Fabian, Waldschmidt, Dirk-Thomas, Radu, Pompilia, Schultheiß, Michael, Peiffer, Kai-Henrik, Ettrich, Thomas J., Weinmann, Arndt, Wege, Henning, Venerito, Marino, Dufour, Jean-Francois, Lange, Christian M., Pinter, Matthias, Waidmann, Oliver
Published in Liver cancer (Basel ) (01.07.2021)
Published in Liver cancer (Basel ) (01.07.2021)
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Serum IgG4 levels outperform IgG4/IgG RNA ratio in differential diagnosis of IgG4-related disease
Schulte, Lucas A., Arnold, Frank, Siegel, Florian, Backhus, Johanna, Beyer, Georg, Weiss, Frank Ulrich, Perkhofer, Lukas, Beutel, Alica, Seufferlein, Thomas, Müller, Martin, Kleger, Alexander
Published in JHEP reports (01.08.2020)
Published in JHEP reports (01.08.2020)
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Journal Article
Organoid-based precision medicine in pancreatic cancer
Beutel, Alica K, Ekizce, Menar, Ettrich, Thomas J, Seufferlein, Thomas, Lindenmayer, Jessica, Gout, Johann, Kleger, Alexander
Published in United European gastroenterology journal (14.11.2024)
Published in United European gastroenterology journal (14.11.2024)
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Journal Article
A Blood-Based Multi Marker Assay Supports the Differential Diagnosis of Early-Stage Pancreatic Cancer
Berger, Andreas W, Schwerdel, Daniel, Reinacher-Schick, Anke, Uhl, Waldemar, Algül, Hana, Friess, Helmut, Janssen, Klaus-Peter, König, Alexander, Ghadimi, Michael, Gallmeier, Eike, Bartsch, Detlef K, Geissler, Michael, Staib, Ludger, Tannapfel, Andrea, Kleger, Alexander, Beutel, Alica, Schulte, Lucas-Alexander, Kornmann, Marko, Ettrich, Thomas J, Seufferlein, Thomas
Published in Theranostics (01.01.2019)
Published in Theranostics (01.01.2019)
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Journal Article
Abstract A055: Multiomics profiling reveals druggable tumor-stroma interactions in ATM-deficient pancreatic cancer
Roger, Elodie, Mummey, Hannah M., Zimmer, Eleni, Ragg, Julia, Lee, Yuna, Gaulton, Kyle J., Beutel, Alica K., Halbrook, Christopher J., Perkhofer, Lukas, Gout, Johann, Kleger, Alexander
Published in Cancer research (Chicago, Ill.) (15.09.2024)
Published in Cancer research (Chicago, Ill.) (15.09.2024)
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Journal Article
Abstract PR023: Targeting gemcitabine resistance in pancreatic cancer
Beutel, Alica Katrin, Singh, Rima, Anaraki, Cecily, Tong, Gregory, Martinez, Thomas, Kleger, Alexander, Jutric, Zeljka, Halbrook, Christopher James
Published in Cancer research (Chicago, Ill.) (15.11.2022)
Published in Cancer research (Chicago, Ill.) (15.11.2022)
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Journal Article
Nintedanib versus placebo in patients receiving mFOLFOX6 for metastatic, chemorefractory colorectal cancer: TRICC-C trial—Final results from the randomized phase II trial of the AIO
Ettrich, Thomas Jens, Berger, Andreas Wolfgang, Decker, Thomas, Hofheinz, Ralf, Heinemann, Volker, Hoffmann, Thomas, Hebart, Holger Frithjof, Herrmann, Thomas, Hannig, Carla Verena, Buechner-Steudel, Petra, Guethle, Melanie, Bartholomaeus, Hanna, Beutel, Alica, Perkhofer, Lukas, Seufferlein, Thomas
Published in Journal of clinical oncology (01.02.2019)
Published in Journal of clinical oncology (01.02.2019)
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Journal Article
Cabozantinib in advanced hepatocellular carcinoma: Efficacy and safety data from an international multicenter real-world cohort
Finkelmeier, Fabian, Scheiner, Bernhard, Leyh, Catherine, Best, Jan, Fründt, Thorben Wilhelm, Czauderna, Carolin, Beutel, Alica, Bettinger, Dominik, Weiß, Johannes, Meischl, Tobias, Kuetting, Fabian, Waldschmidt, Dirk Thomas, Schultheiß, Michael, Ettrich, Thomas Jens, Weinmann, Arndt, Wege, Henning, Venerito, Marino, Lange, Christian, Pinter, Matthias, Waidmann, Oliver
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Abstract C053: Pancreatic cancer patient-derived organoids, preclinical tools for therapeutic profiling, patient response prediction, and tumor evolution
Gout, Johann, Resheq, Yazid J, Lindenmayer, Jessica, Schwab, Julian D, Roger, Elodie, Kraus, Johann M, Ettrich, Thomas, Beutel, Alica K, Perkhofer, Lukas, Kestler, Hans A, Seufferlein, Thomas, Kleger, Alexander
Published in Cancer research (Chicago, Ill.) (15.09.2024)
Published in Cancer research (Chicago, Ill.) (15.09.2024)
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Journal Article
Abstract C052: Repurposing Statins to Target Gemcitabine Resistance in Pancreatic Cancer
Calderon, Sabrina, Beutel, Alica K., Nghiem, Ethan, Singh, Rima, Yousefian, Natalie, Anaraki, Cecily, Gulay, Kevin, Juarez, Dennis, Kleger, Alexander, Seufferlein, Thomas, Muir, Alexander, Jang, Cholsoon, Tiriac, Herve, Fruman, David, Halbrook, Christopher
Published in Cancer research (Chicago, Ill.) (15.09.2024)
Published in Cancer research (Chicago, Ill.) (15.09.2024)
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Journal Article
Abstract A056: Targeting the mevalonate biosynthesis pathway in gemcitabine resistant pancreatic cancer
Beutel, Alica K., Calderon, Sabrina, Nghiem, Ethan, Singh, Rima, Anaraki, Cecily, Gulay, Kevin, Tiriac, Herve, Kleger, Alexander, Seufferlein, Thomas, Muir, Alexander, Jang, Cholsoon, Juarez, Dennis, Fruman, David, Halbrook, Christopher
Published in Cancer research (Chicago, Ill.) (16.01.2024)
Published in Cancer research (Chicago, Ill.) (16.01.2024)
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Journal Article
Abstract B012: Differential stress responses drive asparagine exchange in pancreatic cancer
Anaraki, Cecily, Thurston, Galloway, Steele, Nina G., Kerk, Samuel A., Hong, Hanna, Sajjakulnukit, Peter, Andren, Anthony, Felton, Catherine, Beutel, Alica, Singh, Rima, Christofk, Heather R., Viale, Andrea, Crawford, Howard, di Magliano, Marina Pasca, Jorgensen, Claus, Lyssiotis, Costas A., Halbrook, Christopher J.
Published in Cancer research (Chicago, Ill.) (15.11.2022)
Published in Cancer research (Chicago, Ill.) (15.11.2022)
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