Within Peripheral Blood Mononuclear Cells, Antibody-Dependent Cellular Cytotoxicity of Rituximab-Opsonized Daudi cells Is Promoted by NK Cells and Inhibited by Monocytes due to Shaving
Beum, Paul V, Lindorfer, Margaret A, Taylor, Ronald P
Published in The Journal of immunology (1950) (15.08.2008)
Published in The Journal of immunology (1950) (15.08.2008)
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Journal Article
Loss of CD20 and bound CD20 antibody from opsonized B cells occurs more rapidly because of trogocytosis mediated by Fc receptor-expressing effector cells than direct internalization by the B cells
Beum, Paul V, Peek, Elizabeth M, Lindorfer, Margaret A, Beurskens, Frank J, Engelberts, Patrick J, Parren, Paul W H I, van de Winkel, Jan G J, Taylor, Ronald P
Published in The Journal of immunology (1950) (15.09.2011)
Published in The Journal of immunology (1950) (15.09.2011)
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Journal Article
The Shaving Reaction: Rituximab/CD20 Complexes Are Removed from Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia Cells by THP-1 Monocytes
Beum, Paul V, Kennedy, Adam D, Williams, Michael E, Lindorfer, Margaret A, Taylor, Ronald P
Published in Journal of Immunology (15.02.2006)
Published in Journal of Immunology (15.02.2006)
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Binding of Rituximab, Trastuzumab, Cetuximab, or mAb T101 to Cancer Cells Promotes Trogocytosis Mediated by THP-1 Cells and Monocytes
Beum, Paul V, Mack, David A, Pawluczkowycz, Andrew W, Lindorfer, Margaret A, Taylor, Ronald P
Published in The Journal of immunology (1950) (01.12.2008)
Published in The Journal of immunology (1950) (01.12.2008)
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Thrice-Weekly Low-Dose Rituximab Decreases CD20 Loss via Shaving and Promotes Enhanced Targeting in Chronic Lymphocytic Leukemia
Williams, Michael E, Densmore, John J, Pawluczkowycz, Andrew W, Beum, Paul V, Kennedy, Adam D, Lindorfer, Margaret A, Hamil, Susan H, Eggleton, Jane C, Taylor, Ronald P
Published in Journal of Immunology (15.11.2006)
Published in Journal of Immunology (15.11.2006)
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Journal Article
Rituximab Infusion Promotes Rapid Complement Depletion and Acute CD20 Loss in Chronic Lymphocytic Leukemia
Kennedy, Adam D, Beum, Paul V, Solga, Michael D, DiLillo, David J, Lindorfer, Margaret A, Hess, Charles E, Densmore, John J, Williams, Michael E, Taylor, Ronald P
Published in The Journal of immunology (1950) (01.03.2004)
Published in The Journal of immunology (1950) (01.03.2004)
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Journal Article
Fractionated subcutaneous rituximab is well-tolerated and preserves CD20 expression on tumor cells in patients with chronic lymphocytic leukemia
AUE, Georg, LINDORFER, Margaret A, BEUM, Paul V, PAWLUCZKOWYCZ, Andrew W, VIRE, Berengere, HUGHES, Thomas, TAYLOR, Ronald P, WIESTNER, Adrian
Published in Haematologica (Roma) (01.02.2010)
Published in Haematologica (Roma) (01.02.2010)
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Rapid clearance of rituximab may contribute to the continued high incidence of autoimmune hematologic complications of chemoimmunotherapy for chronic lymphocytic leukemia
Mo, Clifton C, Njuguna, Ndegwa, Beum, Paul V, Lindorfer, Margaret A, Vire, Berengere, Lee, Elinor, Marti, Gerald, Wilson, Wyndham H, Taylor, Ronald P, Wiestner, Adrian
Published in Haematologica (Roma) (01.08.2013)
Published in Haematologica (Roma) (01.08.2013)
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Journal Article
Exhaustion of cytotoxic effector systems may limit monoclonal antibody-based immunotherapy in cancer patients
Beurskens, Frank J, Lindorfer, Margaret A, Farooqui, Mohammed, Beum, Paul V, Engelberts, Patrick, Mackus, Wendy J M, Parren, Paul W H I, Wiestner, Adrian, Taylor, Ronald P
Published in The Journal of immunology (1950) (01.04.2012)
Published in The Journal of immunology (1950) (01.04.2012)
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Binding of Submaximal C1q Promotes Complement-Dependent Cytotoxicity (CDC) of B Cells Opsonized with Anti-CD20 mAbs Ofatumumab (OFA) or Rituximab (RTX): Considerably Higher Levels of CDC Are Induced by OFA than by RTX
Pawluczkowycz, Andrew W, Beurskens, Frank J, Beum, Paul V, Lindorfer, Margaret A, van de Winkel, Jan G. J, Parren, Paul W. H. I, Taylor, Ronald P
Published in The Journal of immunology (1950) (01.07.2009)
Published in The Journal of immunology (1950) (01.07.2009)
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Journal Article
Complement Activation on B Lymphocytes Opsonized with Rituximab or Ofatumumab Produces Substantial Changes in Membrane Structure Preceding Cell Lysis
Beum, Paul V, Lindorfer, Margaret A, Beurskens, Frank, Stukenberg, P. Todd, Lokhorst, Henk M, Pawluczkowycz, Andrew W, Parren, Paul W. H. I, van de Winkel, Jan G. J, Taylor, Ronald P
Published in The Journal of immunology (1950) (01.07.2008)
Published in The Journal of immunology (1950) (01.07.2008)
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Journal Article
Chemoimmunotherapy for relapsed/refractory and progressive 17p13‐deleted chronic lymphocytic leukemia (CLL) combining pentostatin, alemtuzumab, and low‐dose rituximab is effective and tolerable and limits loss of CD20 expression by circulating CLL cells
Zent, Clive S., Taylor, Ronald P., Lindorfer, Margaret A., Beum, Paul V., LaPlant, Betsy, Wu, Wenting, Call, Timothy G., Bowen, Deborah A., Conte, Michael J., Frederick, Lori A., Link, Brian K., Blackwell, Sue E., Veeramani, Suresh, Baig, Nisar A., Viswanatha, David S., Weiner, George J., Witzig, Thomas E.
Published in American journal of hematology (01.07.2014)
Published in American journal of hematology (01.07.2014)
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Journal Article
Penetration of antibody-opsonized cells by the membrane attack complex of complement promotes Ca(2+) influx and induces streamers
Beum, Paul V, Lindorfer, Margaret A, Peek, Elizabeth M, Stukenberg, P Todd, de Weers, Michel, Beurskens, Frank J, Parren, Paul W H I, van de Winkel, Jan G J, Taylor, Ronald P
Published in European journal of immunology (01.08.2011)
Published in European journal of immunology (01.08.2011)
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Journal Article
Penetration of antibody‐opsonized cells by the membrane attack complex of complement promotes Ca2+ influx and induces streamers
Beum, Paul V., Lindorfer, Margaret A., Peek, Elizabeth M., Stukenberg, P. Todd, de Weers, Michel, Beurskens, Frank J., Parren, Paul W. H. I., van de Winkel, Jan G. J., Taylor, Ronald P.
Published in European journal of immunology (01.08.2011)
Published in European journal of immunology (01.08.2011)
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Journal Article
Quantitative analysis of protein co-localization on B cells opsonized with rituximab and complement using the ImageStream multispectral imaging flow cytometer
Beum, Paul V., Lindorfer, Margaret A., Hall, Brian E., George, Thaddeus C., Frost, Keith, Morrissey, Philip J., Taylor, Ronald P.
Published in Journal of immunological methods (20.12.2006)
Published in Journal of immunological methods (20.12.2006)
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Journal Article
Three new assays for rituximab based on its immunological activity or antigenic properties: analyses of sera and plasmas of RTX-treated patients with chronic lymphocytic leukemia and other B cell lymphomas
Beum, Paul V, Kennedy, Adam D, Taylor, Ronald P
Published in Journal of immunological methods (01.06.2004)
Published in Journal of immunological methods (01.06.2004)
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Journal Article
Mucin biosynthesis: upregulation of core 2 β1,6 N -acetylglucosaminyltransferase by retinoic acid and Th2 cytokines in a human airway epithelial cell line
Beum, Paul V., Basma, Hesham, Bastola, Dhundy R., Cheng, Pi-Wan
Published in American journal of physiology. Lung cellular and molecular physiology (01.01.2005)
Published in American journal of physiology. Lung cellular and molecular physiology (01.01.2005)
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