Search Results - "Betz, SF" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of Potent Antagonists of the Antiapoptotic Protein XIAP for the Treatment of Cancer

Discovery of Potent Antagonists of the Antiapoptotic Protein XIAP for the Treatment of Cancer

by Oost, Thorsten K, Sun, Chaohong, Armstrong, Robert C, Al-Assaad, Ali-Samer, Betz, Stephen F, Deckwerth, Thomas L, Ding, Hong, Elmore, Steven W, Meadows, Robert P, Olejniczak, Edward T, Oleksijew, Andrew, Oltersdorf, Tilman, Rosenberg, Saul H, Shoemaker, Alexander R, Tomaselli, Kevin J, Zou, Hua, Fesik, Stephen W
Published in Journal of medicinal chemistry (26.08.2004)

Get full text

Journal Article

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

by Fesik, Stephen W, Liu, Zhihong, Sun, Chaohong, Olejniczak, Edward T, Meadows, Robert P, Betz, Stephen F, Oost, Thorsten, Herrmann, Julia, Wu, Joe C
Published in Nature (London) (21.12.2000)

Get full text

Journal Article

The Crystal Structure of a Quercetin 2,3-Dioxygenase from Bacillus subtilis Suggests Modulation of Enzyme Activity by a Change in the Metal Ion at the Active Site(s)

The Crystal Structure of a Quercetin 2,3-Dioxygenase from Bacillus subtilis Suggests Modulation of Enzyme Activity by a Change in the Metal Ion at the Active Site(s)

by Gopal, B, Madan, Lalima L, Betz, Stephen F, Kossiakoff, Anthony A
Published in Biochemistry (Easton) (11.01.2005)

Get full text

Journal Article

NMR-based screening of proteins containing C-13-labeled methyl groups

NMR-based screening of proteins containing C-13-labeled methyl groups

by Hajduk, PJ, Augeri, DJ, Mack, J, Mendoza, R, Yang, JG, Betz, SF, Fesik, SW
Published in Journal of the American Chemical Society (23.08.2000)

Get full text

Journal Article

Disulfide bonds and the stability of globular proteins

Disulfide bonds and the stability of globular proteins

by Betz, Stephen F.
Published in Protein science (01.10.1993)

Get full text

Journal Article

Overlapping, Nonidentical Binding Sites of Different Classes of Nonpeptide Antagonists for the Human Gonadotropin-Releasing Hormone Receptor

Overlapping, Nonidentical Binding Sites of Different Classes of Nonpeptide Antagonists for the Human Gonadotropin-Releasing Hormone Receptor

by Betz, Stephen F, Reinhart, Greg J, Lio, Francisco M, Chen, Struthers, R. Scott
Published in Journal of medicinal chemistry (26.01.2006)

Get full text

Journal Article

Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization

Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization

by Sanders, William J, Nienaber, Vicki L, Lerner, Claude G, McCall, J. Owen, Merrick, Sean M, Swanson, Susan J, Harlan, John E, Stoll, Vincent S, Stamper, Geoffrey F, Betz, Stephen F, Condroski, Kevin R, Meadows, Robert P, Severin, Jean M, Walter, Karl A, Magdalinos, Peter, Jakob, Clarissa G, Wagner, Rolf, Beutel, Bruce A
Published in Journal of medicinal chemistry (25.03.2004)

Get full text

Journal Article

Non-peptidic small molecule inhibitors of XIAP

Non-peptidic small molecule inhibitors of XIAP

by Park, Cheol-Min, Sun, Chaohong, Olejniczak, Edward T., Wilson, Alan E., Meadows, Robert P., Betz, Stephen F., Elmore, Steven W., Fesik, Stephen W.
Published in Bioorganic & medicinal chemistry letters (01.02.2005)

Get full text

Journal Article

Controlling Topology and Native-like Behavior of de Novo-Designed Peptides: Design and Characterization of Antiparallel Four-Stranded Coiled Coils

Controlling Topology and Native-like Behavior of de Novo-Designed Peptides: Design and Characterization of Antiparallel Four-Stranded Coiled Coils

by Betz, Stephen F, DeGrado, William F
Published in Biochemistry (Easton) (28.05.1996)

Get full text

Journal Article

De novo protein design: from molten globules to native-like states

De novo protein design: from molten globules to native-like states

by Betz, Stephen F., Raleigh, Daniel P., DeGrado, William F.
Published in Current opinion in structural biology (01.08.1993)

Get full text

Journal Article

De Novo Design of Native Proteins: Characterization of Proteins Intended To Fold into Antiparallel, Rop-like, Four-Helix Bundles

De Novo Design of Native Proteins: Characterization of Proteins Intended To Fold into Antiparallel, Rop-like, Four-Helix Bundles

by Betz, Stephen F, Liebman, Paul A, DeGrado, William F
Published in Biochemistry (Easton) (04.03.1997)

Get full text

Journal Article

Native-like and structurally characterized designed α-helical bundles

Native-like and structurally characterized designed α-helical bundles

by Betz, Stephen F, Bryson, James W, DeGrado, William F
Published in Current opinion in structural biology (01.08.1995)

Get full text

Journal Article

A de Novo Designed Protein Mimics the Native State of Natural Proteins

A de Novo Designed Protein Mimics the Native State of Natural Proteins

by Raleigh, Daniel P, Betz, Stephen F, DeGrado, William F
Published in Journal of the American Chemical Society (01.07.1995)

Get full text

Journal Article

Hydrophobic Core Malleability of a De Novo Designed Three-helix Bundle Protein

Hydrophobic Core Malleability of a De Novo Designed Three-helix Bundle Protein

by Walsh, Scott T.R., Sukharev, Vladislav I., Betz, Stephen F., Vekshin, Nikolai L., DeGrado, William F.
Published in Journal of molecular biology (12.01.2001)

Get full text

Journal Article

Function first: a powerful approach to post-genomic drug discovery

Function first: a powerful approach to post-genomic drug discovery

by Betz, Stephen F., Baxter, Susan M., Fetrow, Jacquelyn S.
Published in Drug Discovery Today (15.08.2002)

Get full text

Book Review Journal Article

A strategy for high-throughput assay development using leads derived from nuclear magnetic resonance-based screening

A strategy for high-throughput assay development using leads derived from nuclear magnetic resonance-based screening

by Hajduk, Philip J, Betz, Stephen F, Mack, Jamey, Ruan, Xiaoan, Towne, Danli L, Lerner, Claude G, Beutel, Bruce A, Fesik, Stephen W
Published in Journal of biomolecular screening (01.10.2002)

Get full text

Journal Article

Introduction of a disulfide bond into cytochrome c stabilizes a compact denatured state

Introduction of a disulfide bond into cytochrome c stabilizes a compact denatured state

by Betz, Stephen F, Pielak, Gary J
Published in Biochemistry (Easton) (15.12.1992)

Get full text

Journal Article

Solution Structure of the Cytohesin-1 (B2-1) Sec7 Domain and Its Interaction with the GTPase ADP Ribosylation Factor 1

Solution Structure of the Cytohesin-1 (B2-1) Sec7 Domain and Its Interaction with the GTPase ADP Ribosylation Factor 1

by Betz, Stephen F., Schnuchel, Arndt, Wang, Hong, Olejniczak, Edward T., Meadows, Robert P., Lipsky, Brian P., Edith A. S. Harris, Staunton, Donald E., Fesik, Stephen W.
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.1998)

Get full text

Journal Article

Unusual Effects of an Engineered Disulfide on Global and Local Protein Stability

Unusual Effects of an Engineered Disulfide on Global and Local Protein Stability

by Betz, Stephen F, Marmorino, Jennifer L, Saunders, Aleister J, Doyle, Donald F, Young, Gregory B, Pielak, Gary J
Published in Biochemistry (Easton) (11.06.1996)

Get full text

Journal Article

Protein thermal denaturation, side-chain models, and evolution: amino acid substitutions at a conserved helix-helix interface

Protein thermal denaturation, side-chain models, and evolution: amino acid substitutions at a conserved helix-helix interface

by Pielak, Gary J, Auld, Douglas S, Beasley, James R, Betz, Stephen F, Cohen, David S, Doyle, Donald F, Finger, Shelley A, Fredericks, Zoey L, Hilgen-Willis, Sharon
Published in Biochemistry (Easton) (14.03.1995)

Get full text

Journal Article