Challenges associated with homologous directed repair using CRISPR-Cas9 and TALEN to edit the DMD genetic mutation in canine Duchenne muscular dystrophy
Mata López, Sara, Balog-Alvarez, Cynthia, Vitha, Stanislav, Bettis, Amanda K, Canessa, Emily H, Kornegay, Joe N, Nghiem, Peter P
Published in PloS one (21.01.2020)
Published in PloS one (21.01.2020)
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Journal Article
Short-term treatment of golden retriever muscular dystrophy (GRMD) dogs with rAAVrh74.MHCK7.GALGT2 induces muscle glycosylation and utrophin expression but has no significant effect on muscle strength
Martin, Paul T, Zygmunt, Deborah A, Ashbrook, Anna, Hamilton, Sonia, Packer, Davin, Birch, Sharla M, Bettis, Amanda K, Balog-Alvarez, Cynthia J, Guo, Lee-Jae, Nghiem, Peter P, Kornegay, Joe N
Published in PloS one (26.03.2021)
Published in PloS one (26.03.2021)
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Journal Article
Correction: Challenges associated with homologous directed repair using CRISPR-Cas9 and TALEN to edit the DMD genetic mutation in canine Duchenne muscular dystrophy
Mata López, Sara, Balog-Alvarez, Cynthia, Vitha, Stanislav, Bettis, Amanda K, Canessa, Emily H, Kornegay, Joe N, Nghiem, Peter P
Published in PloS one (22.10.2020)
Published in PloS one (22.10.2020)
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Journal Article
Expiratory dysfunction in young dogs with golden retriever muscular dystrophy
Hawkins, Eleanor C., Bettis, Amanda K., Kornegay, Joe N.
Published in Neuromuscular disorders : NMD (01.11.2020)
Published in Neuromuscular disorders : NMD (01.11.2020)
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Journal Article
Oxidative damage to urinary proteins from the GRMD dog and mdx mouse as biomarkers of dystropathology in Duchenne muscular dystrophy
Terrill, Jessica R, Al-Mshhdani, Basma A, Duong, Marisa N, Wingate, Catherine D, Abbas, Zahra, Baustista, Angelo P, Bettis, Amanda K, Balog-Alvarez, Cynthia J, Kornegay, Joe N, Nghiem, Peter P, Grounds, Miranda D, Arthur, Peter G
Published in PloS one (08.10.2020)
Published in PloS one (08.10.2020)
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Journal Article
Assessment of systemic AAV-microdystrophin gene therapy in the GRMD model of Duchenne muscular dystrophy
Birch, Sharla M, Lawlor, Michael W, Conlon, Thomas J, Guo, Lee-Jae, Crudele, Julie M, Hawkins, Eleanor C, Nghiem, Peter P, Ahn, Mihye, Meng, Hui, Beatka, Margaret J, Fickau, Brittany A, Prieto, Juan C, Styner, Martin A, Struharik, Michael J, Shanks, Courtney, Brown, Kristy J, Golebiowski, Diane, Bettis, Amanda K, Balog-Alvarez, Cynthia J, Clement, Nathalie, Coleman, Kirsten E, Corti, Manuela, Pan, Xiufang, Hauschka, Stephen D, Gonzalez, J Patrick, Morris, Carl A, Schneider, Joel S, Duan, Dongsheng, Chamberlain, Jeffrey S, Byrne, Barry J, Kornegay, Joe N
Published in Science translational medicine (04.01.2023)
Published in Science translational medicine (04.01.2023)
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Journal Article
Creation and characterization of an immortalized canine myoblast cell line: Myok9
López, Sara Mata, Balog-Alvarez, Cynthia, Canessa, Emily H., Hathout, Yetrib, Brown, Kristy J., Vitha, Stanislav, Bettis, Amanda K., Boehler, Jessica, Kornegay, Joe N., Nghiem, Peter P.
Published in Mammalian genome (01.04.2020)
Published in Mammalian genome (01.04.2020)
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Journal Article
Natural History of Cardiomyopathy in Adult Dogs With Golden Retriever Muscular Dystrophy
Guo, Lee-Jae, Soslow, Jonathan H, Bettis, Amanda K, Nghiem, Peter P, Cummings, Kevin J, Lenox, Mark W, Miller, Matthew W, Kornegay, Joe N, Spurney, Christopher F
Published in Journal of the American Heart Association (20.08.2019)
Published in Journal of the American Heart Association (20.08.2019)
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Journal Article
Glucose Metabolism as a Pre-clinical Biomarker for the Golden Retriever Model of Duchenne Muscular Dystrophy
Schneider, Sarah Morar, Sridhar, Vidya, Bettis, Amanda K., Heath-Barnett, Heather, Balog-Alvarez, Cynthia J., Guo, Lee-Jae, Johnson, Rachel, Jaques, Scott, Vitha, Stanislav, Glowcwski, Alan C., Kornegay, Joe N., Nghiem, Peter P.
Published in Molecular imaging and biology (01.10.2018)
Published in Molecular imaging and biology (01.10.2018)
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Journal Article
Use of the six-minute walk test to characterize golden retriever muscular dystrophy
Acosta, Austin R, Van Wie, Emiko, Stoughton, William B, Bettis, Amanda K, Barnett, Heather H, LaBrie, Nicholas R, Balog-Alvarez, Cynthia J, Nghiem, Peter P, Cummings, Kevin J, Kornegay, Joe N
Published in Neuromuscular disorders : NMD (01.12.2016)
Published in Neuromuscular disorders : NMD (01.12.2016)
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Journal Article
Changes in Muscle Metabolism are Associated with Phenotypic Variability in Golden Retriever Muscular Dystrophy
Nghiem, Peter P, Bello, Luca, Stoughton, William B, López, Sara Mata, Vidal, Alexander H, Hernandez, Briana V, Hulbert, Katherine N, Gourley, Taylor R, Bettis, Amanda K, Balog-Alvarez, Cynthia J, Heath-Barnett, Heather, Kornegay, Joe N
Published in The Yale journal of biology & medicine (01.09.2017)
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Published in The Yale journal of biology & medicine (01.09.2017)
Journal Article
Abstract 17108: Natural History of Cardiomyopathy and Cardiac Stress Response in Young Dogs With Golden Retriever Muscular Dystrophy
Guo, Lee-Jae, Bettis, Amanda K, Nghiem, Peter P, Soslow, Jonathan H, SPURNEY, Christopher F, Kornegay, Joe N
Published in Circulation (New York, N.Y.) (17.11.2020)
Published in Circulation (New York, N.Y.) (17.11.2020)
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Journal Article
Short-term treatment of golden retriever muscular dystrophy
Martin, Paul T, Zygmunt, Deborah A, Ashbrook, Anna, Hamilton, Sonia, Packer, Davin, Birch, Sharla M, Bettis, Amanda K, Balog-Alvarez, Cynthia J, Guo, Lee-Jae, Nghiem, Peter P, Kornegay, Joe N
Published in PloS one (26.03.2021)
Published in PloS one (26.03.2021)
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Journal Article
Whole genome sequencing reveals a 7 base-pair deletion in DMD exon 42 in a dog with muscular dystrophy
Nghiem, Peter P., Bello, Luca, Balog-Alvarez, Cindy, López, Sara Mata, Bettis, Amanda, Barnett, Heather, Hernandez, Briana, Schatzberg, Scott J., Piercy, Richard J., Kornegay, Joe N.
Published in Mammalian genome (01.04.2017)
Published in Mammalian genome (01.04.2017)
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Journal Article
Computational Texture Features and Mechanical Anisotropy Reflect Structure and Composition of Dystrophic Canine Skeletal Muscle
Moore, Christopher J., Montgomery, Stephanie, Prieto, Juan, Selzo, Mallory, Spaulding, Kathy, Bettis, Amanda, Heath-Barnett, Heather, Styner, Martin, Caughey, Melissa, Kornegay, Joe, Gallippi, Caterina M.
Published in 2018 IEEE International Ultrasonics Symposium (IUS) (01.10.2018)
Published in 2018 IEEE International Ultrasonics Symposium (IUS) (01.10.2018)
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Conference Proceeding
VisR ultrasound evaluation of dystrophic muscle degeneration in a dog cross-section and comparison to histology and MRI
Selzo, Mallory R., Kornegay, Joe N., Spaulding, Kathy A., Bettis, Amanda, Snook, Eric, Styner, Martin, Jiahui Wang, Gallippi, Caterina M.
Published in 2015 IEEE International Ultrasonics Symposium (IUS) (01.10.2015)
Published in 2015 IEEE International Ultrasonics Symposium (IUS) (01.10.2015)
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Conference Proceeding
Management of Research Animal Breeding Colonies
Elliott, James J., Miller, Charles T., Hagarman, James A., Kelley, Stephen T., Tardif, Suzette D., Hacker, Sander O., Bettis, Amanda
Published in Management of Animal Care and Use Programs in Research, Education, and Testing (2017)
Published in Management of Animal Care and Use Programs in Research, Education, and Testing (2017)
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Book Chapter