312 A Novel Assay for the Met Inhibitory Activity of MGCD265 in Plasma From Solid Tumor Patients in a Dose Escalating Phase I Study
Fournel, M, Wang, J, Beaulieu, N, Bonfils, C, Hurwitz, H, Shapiro, G, Kollmannsberger, C.K, Juretic, M, Besterman, J.M, Maroun, C.R
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Published in European journal of cancer (1990) (01.11.2012)
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81 POSTER Preclinical pharmacodynamic markers of MGCD265, a potent orally active c-Met/VEGFR multitargeted kinase inhibitor in Phase I clinical trials
Beaulieu, N, Dupont, I, Beaulieu, C, Nguyen, H, Ste-Croix, H, Claridge, S, Isakovic, L, Vaisburg, A, Besterman, J.M, Maroun, C
Published in European journal of cancer supplements (2008)
Published in European journal of cancer supplements (2008)
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Mammalian DNA ligase II is highly homologous with vaccinia DNA ligase. Identification of the DNA ligase II active site for enzyme-adenylate formation
Wang, Y.C., Burkhart, W.A., Mackey, Z.B., Moyer, M.B., Ramos, W, Husain, I, Chen, J, Besterman, J.M., Tomkinson, A.E.
Published in The Journal of biological chemistry (16.12.1994)
Published in The Journal of biological chemistry (16.12.1994)
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Activity of MGCD290, a Hos2 Histone Deacetylase Inhibitor, in Combination with Azole Antifungals against Opportunistic Fungal Pathogens
Pfaller, M.A, Messer, S.A, Georgopapadakou, N, Martell, L.A, Besterman, J.M, Diekema, D.J
Published in Journal of Clinical Microbiology (01.12.2009)
Published in Journal of Clinical Microbiology (01.12.2009)
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A phase I pharmacokinetic and pharmacodynamic study of the DNA methyltransferase 1 inhibitor MG98 administered twice weekly
Stewart, D. J., Donehower, R. C., Eisenhauer, E. A., Wainman, N., Shah, A. K., Bonfils, C., MacLeod, A. R., Besterman, J. M., Reid, G. K.
Published in Annals of oncology (01.05.2003)
Published in Annals of oncology (01.05.2003)
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Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination
Chen, Jingwen, Tomkinson, Alan E., Ramos, William, Mackey, Zachary B., Danehower, Sue, Walter, Christi A., Schultz, Roger A., Besterman, Jeffrey M., Husain, Intisar
Published in Molecular and Cellular Biology (01.10.1995)
Published in Molecular and Cellular Biology (01.10.1995)
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Lupane Derivatives from Lophopetalum wallichii with Farnesyl Protein Transferase Inhibitory Activity
Sturm, Sonja, Gil, Roberto R, Chai, Hee-Byung, Ngassapa, Olipa D, Santisuk, Thawatchai, Reutrakul, Vichai, Howe, Anne, Moss, Marcia, Besterman, Jeffrey M, Yang, Shi-Lin, Farthing, John E, Tait, R. Murray, Lewis, Jane A, O'Neill, Melanie J, Farnsworth, Norman R, Cordell, Geoffrey A, Pezzuto, John M, Kinghorn, A. Douglas
Published in Journal of natural products (Washington, D.C.) (01.07.1996)
Published in Journal of natural products (Washington, D.C.) (01.07.1996)
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Stimulated release of arachidonate and prostaglandins is vectorial in MDCK epithelial cells
Cortizo, A.M., Besterman, J.M., Leitner, P.P., Chandrabose, K.A.
Published in Prostaglandins (01.10.1992)
Published in Prostaglandins (01.10.1992)
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