Activity of MGCD290, a Hos2 Histone Deacetylase Inhibitor, in Combination with Azole Antifungals against Opportunistic Fungal Pathogens
Pfaller, M.A, Messer, S.A, Georgopapadakou, N, Martell, L.A, Besterman, J.M, Diekema, D.J
Published in Journal of Clinical Microbiology (01.12.2009)
Published in Journal of Clinical Microbiology (01.12.2009)
Get full text
Journal Article
A phase I pharmacokinetic and pharmacodynamic study of the DNA methyltransferase 1 inhibitor MG98 administered twice weekly
Stewart, D. J., Donehower, R. C., Eisenhauer, E. A., Wainman, N., Shah, A. K., Bonfils, C., MacLeod, A. R., Besterman, J. M., Reid, G. K.
Published in Annals of oncology (01.05.2003)
Published in Annals of oncology (01.05.2003)
Get full text
Journal Article
Models of Human Metastatic Colon Cancer in Nude Mice Orthotopically Constructed by Using Histologically Intact Patient Specimens
Fu, Xinyu, Besterman, Jeffrey M., Monosov, Ann, Hoffman, Robert M.
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.1991)
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.1991)
Get full text
Journal Article
Elevation of topoisomerase I messenger RNA, protein, and catalytic activity in human tumors : demonstration of tumor-type specificity and implications for cancer chemotherapy
INTISAR HUSAIN, MOHLER, J. L, SEIGLER, H. F, BESTERMAN, J. M
Published in Cancer research (Chicago, Ill.) (15.01.1994)
Get full text
Published in Cancer research (Chicago, Ill.) (15.01.1994)
Journal Article
Synthesis and Antitumor Activity of Novel Water Soluble Derivatives of Camptothecin as Specific Inhibitors of Topoisomerase I
Luzzio, Michael J, Besterman, Jeffrey M, Emerson, David L, Evans, Michael G, Lackey, Karen, Leitner, Peter L, McIntyre, Gordon, Morton, Bradley, Myers, Peter L, Peel, Michael, Sisco, Jay M, Sternbach, Daniel D, Tong, Wei-Qin, Truesdale, Ann, Uehling, David E, Vuong, Alan, Yates, Julie
Published in Journal of medicinal chemistry (01.02.1995)
Published in Journal of medicinal chemistry (01.02.1995)
Get full text
Journal Article
Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination
Chen, Jingwen, Tomkinson, Alan E., Ramos, William, Mackey, Zachary B., Danehower, Sue, Walter, Christi A., Schultz, Roger A., Besterman, Jeffrey M., Husain, Intisar
Published in Molecular and Cellular Biology (01.10.1995)
Published in Molecular and Cellular Biology (01.10.1995)
Get full text
Journal Article
Sulfonamide anilides, a novel class of histone deacetylase inhibitors, are antiproliferative against human tumors
FOURNEL, Marielle, TRACHY-BOURGET, Marie-Claude, DELORME, Daniel, MACLEOD, A. Robert, BESTERMAN, Jeffrey M, ZUOMEI LI, YAN, P. Theresa, KALITA, Ann, BONFILS, Claire, BEAULIEU, Carole, FRECHETTE, Sylvie, LEIT, Silvana, ABOU-KHALIL, Elie, WOO, Soon-Hyung
Published in Cancer research (Chicago, Ill.) (01.08.2002)
Get full text
Published in Cancer research (Chicago, Ill.) (01.08.2002)
Journal Article
395 MGCD265, an orally active Met/VEGFR multitargeted kinase inhibitor, in combination with erlotinib: clinical and preclinical experience
Patnaik, A, Besterman, J, Tolcher, A.W, Mehran, M, Drouin, M, Maroun, C, Bonfils, C, Beeram, M, Martell, R, Papadopoulos, K
Published in European journal of cancer supplements (2010)
Published in European journal of cancer supplements (2010)
Get full text
Journal Article
396 MGCD265, an orally active Met/VEGFR multitargeted kinase inhibitor, in combination with docetaxel: clinical and preclinical experience
O'Dwyer, P, Papadopoulos, K, Amaravadi, R, Harlacker, K, Beeram, M, Drouin, M, Mehran, M, Besterman, J, Maroun, C, Patnaik, A
Published in European journal of cancer supplements (2010)
Published in European journal of cancer supplements (2010)
Get full text
Journal Article
Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange
J M Besterman, W S May, Jr, H LeVine, 3rd, E J Cragoe, Jr, P Cuatrecasas
Published in The Journal of biological chemistry (01.01.1985)
Published in The Journal of biological chemistry (01.01.1985)
Get full text
Journal Article
Collagen cross-link metabolites in urine as markers of bone metastases in prostatic carcinoma
Miyamoto, K K, McSherry, S A, Robins, S P, Besterman, J M, Mohler, J L
Published in The Journal of urology (01.04.1994)
Published in The Journal of urology (01.04.1994)
Get more information
Journal Article
In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues
EMERSON, D. L, BESTERMAN, J. M, BROWN, H. R, EVANS, M. G, LEITNER, P. P, LUZZIO, M. J, SHAFFER, J. E, STERNBACH, D. D, UEHLING, D, VUONG, A
Published in Cancer research (Chicago, Ill.) (01.02.1995)
Get full text
Published in Cancer research (Chicago, Ill.) (01.02.1995)
Journal Article
Mammalian DNA ligase II is highly homologous with vaccinia DNA ligase. Identification of the DNA ligase II active site for enzyme-adenylate formation
Wang, Y.C., Burkhart, W.A., Mackey, Z.B., Moyer, M.B., Ramos, W, Husain, I, Chen, J, Besterman, J.M., Tomkinson, A.E.
Published in The Journal of biological chemistry (16.12.1994)
Published in The Journal of biological chemistry (16.12.1994)
Get full text
Journal Article
Protein Kinase C Phosphorylates Topoisomerase II: Topoisomerase Activation and Its Possible Role in Phorbol Ester-Induced Differentiation of HL-60 Cells
Sahyoun, Naji, Wolf, Marlene, Besterman, Jeffrey, Hsieh, Tao-Shih, Sander, Miriam, LeVine, Harry, Chang, Kwen-Jen, Cuatrecasas, Pedro
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.1986)
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.1986)
Get full text
Journal Article