Comparison of the mouse Embryonic Stem cell Test, the rat Whole Embryo Culture and the Zebrafish Embryotoxicity Test as alternative methods for developmental toxicity testing of six 1,2,4-triazoles
de Jong, Esther, Barenys, Marta, Hermsen, Sanne A.B., Verhoef, Aart, Ossendorp, Bernadette C., Bessems, Jos G.M., Piersma, Aldert H.
Published in Toxicology and applied pharmacology (01.06.2011)
Published in Toxicology and applied pharmacology (01.06.2011)
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Journal Article
Case study illustrating the WHO IPCS guidance on characterization and application of physiologically based pharmacokinetic models in risk assessment
Meek, M.E. (Bette), Barton, Hugh A., Bessems, Jos G., Lipscomb, John C., Krishnan, Kannan
Published in Regulatory toxicology and pharmacology (01.06.2013)
Published in Regulatory toxicology and pharmacology (01.06.2013)
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Journal Article
Quantitative Extrapolation of In Vitro Whole Embryo Culture Embryotoxicity Data to Developmental Toxicity In Vivo Using the Benchmark Dose Approach
Piersma, Aldert H., Janer, Gemma, Wolterink, Gerrit, Bessems, Jos G. M., Hakkert, Betty C., Slob, Wout
Published in Toxicological sciences (01.01.2008)
Published in Toxicological sciences (01.01.2008)
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Journal Article
Human risk assessment of dermal and inhalation exposures to chemicals assessed by route-to-route extrapolation: The necessity of kinetic data
Geraets, Liesbeth, Bessems, Jos G.M., Zeilmaker, Marco J., Bos, Peter M.J.
Published in Regulatory toxicology and pharmacology (01.10.2014)
Published in Regulatory toxicology and pharmacology (01.10.2014)
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Journal Article
Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches
Coecke, Sandra, Pelkonen, Olavi, Leite, Sofia Batista, Bernauer, Ulrike, Bessems, Jos GM, Bois, Frederic Y., Gundert-Remy, Ursula, Loizou, George, Testai, Emanuela, Zaldívar, José-Manuel
Published in Toxicology in vitro (01.08.2013)
Published in Toxicology in vitro (01.08.2013)
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Journal Article
Application of toxicogenomics in hepatic systems toxicology for risk assessment: Acetaminophen as a case study
Kienhuis, Anne S., Bessems, Jos G.M., Pennings, Jeroen L.A., Driessen, Marja, Luijten, Mirjam, van Delft, Joost H.M., Peijnenburg, Ad A.C.M., der Ven, Leo T.M. van
Published in Toxicology and applied pharmacology (15.01.2011)
Published in Toxicology and applied pharmacology (15.01.2011)
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Journal Article
PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment: recommendations from a joint EPAA--EURL ECVAM ADME workshop
Bessems, Jos G, Loizou, George, Krishnan, Kannan, Clewell, 3rd, Harvey J, Bernasconi, Camilla, Bois, Frederic, Coecke, Sandra, Collnot, Eva-Maria, Diembeck, Walter, Farcal, Lucian Romeo, Geraets, Liesbeth, Gundert-Remy, Ursula, Kramer, Nynke, Küsters, Gabriele, Leite, Sofia B, Pelkonen, Olavi R, Schröder, Klaus, Testai, Emanuela, Wilk-Zasadna, Iwona, Zaldívar-Comenges, José-Manuel
Published in Regulatory toxicology and pharmacology (01.02.2014)
Published in Regulatory toxicology and pharmacology (01.02.2014)
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Journal Article
Evaluation of semi-generic PBTK modeling for emergency risk assessment after acute inhalation exposure to volatile hazardous chemicals
Olie, J. Daniël N., Bessems, Jos G., Clewell, Harvey J., Meulenbelt, Jan, Hunault, Claudine C.
Published in Chemosphere (Oxford) (01.08.2015)
Published in Chemosphere (Oxford) (01.08.2015)
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Journal Article
Finding maximal transcriptome differences between reprotoxic and non-reprotoxic phthalate responses in rat testis
Yuan, Xiaolian, Jonker, Martijs J., de Wilde, Jillian, Verhoef, Aart, Wittink, Floyd R.A., van Benthem, Jan, Bessems, Jos G., Hakkert, Betty C., Kuiper, Raoul V., van Steeg, Harry, Breit, Timo M., Luijten, Mirjam
Published in Journal of applied toxicology (01.07.2011)
Published in Journal of applied toxicology (01.07.2011)
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Journal Article
Biotransformation of 1,2-dihydronaphthalene and 1,2-dihydroanthracene by rat liver microsomes and purified cytochromes P-450. Formation of arene hydrates of naphthalene and anthracene
Boyd, Derek R, Sharma, Narain D, Agarwal, Rajiv, McMordie, R. Austin S, Bessems, Jos G. M, van Ommen, Ben, van Bladeren, Peter J
Published in Chemical research in toxicology (01.11.1993)
Published in Chemical research in toxicology (01.11.1993)
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Journal Article
Neurobehavioural evaluation and kinetics of inhalation of constant or fluctuating toluene concentrations in human volunteers
Lammers, Jan H.C.M., Meuling, Wim J.A., Muijser, Hans, Freidig, Andreas P., Bessems, Jos G.M.
Published in Environmental toxicology and pharmacology (01.11.2005)
Published in Environmental toxicology and pharmacology (01.11.2005)
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Journal Article
PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment
Bessems, Jos G., Loizou, George, Krishnan, Kannan, Clewell, Harvey J., Bernasconi, Camilla, Bois, Frederic, Coecke, Sandra, Collnot, Eva-Maria, Diembeck, Walter, Farcal, Lucian Romeo, Geraets, Liesbeth, Gundert-Remy, Ursula, Kramer, Nynke, Küsters, Gabriele, Leite, Sofia B., Pelkonen, Olavi R., Schröder, Klaus, Testai, Emanuela, Wilk-Zasadna, Iwona, Zaldívar-Comenges, José-Manuel
Published in Regulatory toxicology and pharmacology (01.02.2014)
Published in Regulatory toxicology and pharmacology (01.02.2014)
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Journal Article
Dermal Absorption of Pesticides
Hakkert, Betty C, van de Sandt, J.J.M. (Han), Bessems, Jos G.M, de Heer, Cees
Published in Occupational and Residential Exposure Assessment for Pesticides (14.01.2005)
Published in Occupational and Residential Exposure Assessment for Pesticides (14.01.2005)
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Book Chapter