Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis
Wang, Si, Rijk, Jeroen C W, Besselink, Harrie T, Houtman, René, Peijnenburg, Ad A C M, Brouwer, Abraham, Rietjens, Ivonne M C M, Bovee, Toine F H
Published in Toxicological sciences (01.09.2014)
Published in Toxicological sciences (01.09.2014)
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Journal Article
Intra- and interlaboratory calibration of the DR CALUX® bioassay for the analysis of dioxins and dioxin-like chemicals in sediments
Besselink, Harrie T., Schipper, Cor, Klamer, Hans, Leonards, Pim, Verhaar, Henk, Felzel, Emiel, Murk, Albertinka J., Thain, John, Hosoe, Kazunori, Schoeters, Greet, Legler, Juliette, Brouwer, Bram
Published in Environmental toxicology and chemistry (01.12.2004)
Published in Environmental toxicology and chemistry (01.12.2004)
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Journal Article
Toxicity of TCDD in European flounder ( Platichthys flesus) with emphasis on histopathology and cytochrome P450 1A induction in several organ systems
Grinwis, G.C.M, Besselink, H.T, van den Brandhof, E.J, Bulder, A.S, Engelsma, M.Y, Kuiper, R.V, Wester, P.W, Vaal, M.A, Vethaak, A.D, Vos, J.G
Published in Aquatic toxicology (01.10.2000)
Published in Aquatic toxicology (01.10.2000)
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Journal Article
Low Inducibility of CYP1A Activity by Polychlorinated Biphenyls (PCBs) in Flounder (Platichthys flesus): Characterization of the Ah Receptor and the Role of CYP1A Inhibition
Besselink, H.T., Denison, M.S., Hahn, M.E., Karchner, S.I., Vethaak, A.D., Koeman, J.H., Brouwer, A.
Published in Toxicological sciences (01.06.1998)
Published in Toxicological sciences (01.06.1998)
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Journal Article
HIGH INDUCTION OF CYTOCHROME P4501A ACTIVITY WITHOUT CHANGES IN RETINOID AND THYROID HORMONE LEVELS IN FLOUNDER (PLATICHTHYS FLESUS) EXPOSED TO 2,3,7,8-TETRACHLORODIBENZO-p-DIOXIN
Besselink, H.T., van Santen, E., Vorstman, W., Vethaak, A.D., Koeman, J.H., Brouwer, A.
Published in Environmental toxicology and chemistry (01.04.1997)
Published in Environmental toxicology and chemistry (01.04.1997)
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Journal Article
Low inducibility of CYP 1A activity by polychlorinated biphenyls (PCBs) in flounder (Platichtys flesus): characterization of the Ah receptor and the role of CYP1A inhibition
Besselink, H.T, Denison, M.S, Hahn, M.H, Karchner, S.I, Vethaak, A.D, Koeman, J.H, Brouwer, A
Published in Toxicological sciences (1998)
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Published in Toxicological sciences (1998)
Journal Article
Low hepatic 7-ethoxyresorufin- O-deethylase (EROD) activity and minor alterations in retinoid and thyroid hormone levels in flounder ( Platichthys flesus) exposed to the polychlorinated biphenyl (PCB) mixture, Clophen A50
Besselink, H.T., van Beusekom, S., Roex, E., Vethaak, A.D., Koeman, J.H., Brouwer, A.
Published in Environmental pollution (1987) (1996)
Published in Environmental pollution (1987) (1996)
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Journal Article
High induction of cytochrome p4501a activity without changes in retinoid and thyroid hormone levels in flounder (Platichthys flesus) exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin
Besselink, H. T., van Santen, E., Vorstman, W., Vethaak, A. D., Koeman, J. H., Brouwer, A.
Published in Environmental toxicology and chemistry (01.04.1997)
Published in Environmental toxicology and chemistry (01.04.1997)
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Journal Article
Alterations in plasma and hepatic retinoid levels in flounder ( Platichthys flesus) after chronic exposure to contaminated harbour sludge in a mesocosm study
Besselink, Harry T, Flipsen, Esther M.T.E, Eggens, Martin L, Vethaak, A.Dick, Koeman, Jan H, Brouwer, Abraham
Published in Aquatic toxicology (01.08.1998)
Published in Aquatic toxicology (01.08.1998)
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Journal Article
Low hepatic 7-ethoxypresofurin-o-deethylase (erod)activity and minor alterations in retinoid and thyroid hormone levels in flounder (Platichtys flesus) exposed to the polychlorinated biphenyl (PCB) mixture, clophen A50
Besselink, H.T, Beusekom, S., van, Roex, E, Vethaak, A.D, Koeman, J.H, Brouwer, A
Published in Environmental pollution (1987) (1996)
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Published in Environmental pollution (1987) (1996)
Journal Article
The liver, kidney, and thyroid toxicity of chlorinated benzenes
Besten, C. den (Agricultural University, Wageningen, The Netherlands), Vet, J.J.R.M, Besselink, H.T, Kiel, G.S, Berkel, B.J.M. van, Beems, R, Bladeren, P.J. van
Published in Toxicology and applied pharmacology (01.10.1991)
Published in Toxicology and applied pharmacology (01.10.1991)
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Journal Article
Post-mortem stability of blubber DLCs, PCB and tDDT in by-caught harbour porpoises (Phocoena phocoena)
Borrell, A, Aquilar, A, Zeljkovic, S, Brouwer, A, Besselink, H.T, Koopman, H, Read, A, Reijnders, P.J
Year of Publication 2007
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Year of Publication 2007
Journal Article
Toxicity of TCDD in European flounder (Platichthys flesus) with emphasis on histopathology and cytochrome P450 1A induction in several organ systems
Grinwis, G.C.M, Besselink, H.T, Brandhof, E.J. van den, Bulder, A.S, Engelsma, M.Y, Kuiper, R.V, Wester, P.W, Vaal, M.A, Vethaak, A.D, Vos, J.G
Year of Publication 2000
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Year of Publication 2000
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