Combination of an Oxindole Derivative with (-)-β-Elemene Alters Cell Death Pathways in FLT3/ITD + Acute Myeloid Leukemia Cells
Alanazi, Jowaher, Bender, Onur, Dogan, Rumeysa, Malik, Jonaid Ahmad, Atalay, Arzu, Ali, Taha F S, Beshr, Eman A M, Shawky, Ahmed M, Aly, Omar M, Alqahtani, Yasir Nasser H, Anwar, Sirajudheen
Published in Molecules (Basel, Switzerland) (01.07.2023)
Published in Molecules (Basel, Switzerland) (01.07.2023)
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Development of Halogenated-Chalcones Bearing with Dimethoxy Phenyl Head as Monoamine Oxidase-B Inhibitors
Rehuman, Nisha Abdul, Oh, Jong Min, Abdelgawad, Mohamed A, Beshr, Eman A M, Abourehab, Mohammed A S, Gambacorta, Nicola, Nicolotti, Orazio, Jat, Rakesh Kumar, Kim, Hoon, Mathew, Bijo
Published in Pharmaceuticals (Basel, Switzerland) (16.09.2022)
Published in Pharmaceuticals (Basel, Switzerland) (16.09.2022)
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Design, Synthesis, and Biological Evaluation of Novel 3-Cyanopyridone/Pyrazoline Hybrids as Potential Apoptotic Antiproliferative Agents Targeting EGFR/BRAFV600E Inhibitory Pathways
Al-Wahaibi, Lamya H., Abou-Zied, Hesham A., Hisham, Mohamed, Beshr, Eman A. M., Youssif, Bahaa G. M., Bräse, Stefan, Hayallah, Alaa M., Abdel-Aziz, Mohamed
Published in Molecules (Basel, Switzerland) (12.09.2023)
Published in Molecules (Basel, Switzerland) (12.09.2023)
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Design, Synthesis, Antiproliferative Actions, and DFT Studies of New Bis–Pyrazoline Derivatives as Dual EGFR/BRAFV600E Inhibitors
Al-Wahaibi, Lamya H., Abou-Zied, Hesham A., Beshr, Eman A. M., Youssif, Bahaa G. M., Hayallah, Alaa M., Abdel-Aziz, Mohamed
Published in International journal of molecular sciences (22.05.2023)
Published in International journal of molecular sciences (22.05.2023)
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Pyrrolizine/Indolizine-NSAID Hybrids: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies
Abourehab, Mohammed A S, Alqahtani, Alaa M, Almalki, Faisal A, Zaher, Dana M, Abdalla, Ashraf N, Gouda, Ahmed M, Beshr, Eman A M
Published in Molecules (Basel, Switzerland) (30.10.2021)
Published in Molecules (Basel, Switzerland) (30.10.2021)
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Design and Synthesis of New Hydantoin Acetanilide Derivatives as Anti-NSCLC Targeting EGFRL858R/T790M Mutations
Hassanin, Moamen A., Mustafa, Muhamad, Abourehab, Mohammed A. S., Hassan, Heba A., Aly, Omar M., Beshr, Eman A. M.
Published in Pharmaceuticals (Basel, Switzerland) (12.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (12.07.2022)
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Spirohydantoins and 1,2,4-triazole-3-carboxamide derivatives as inhibitors of histone deacetylase: Design, synthesis, and biological evaluation
Aboeldahab, Alshimaa M.A., Beshr, Eman A.M., Shoman, Mai E., Rabea, Safwat M., Aly, Omar M.
Published in European journal of medicinal chemistry (25.02.2018)
Published in European journal of medicinal chemistry (25.02.2018)
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Design, synthesis, and molecular docking of novel pyrazole-chalcone analogs of lonazolac as 5-LOX, iNOS and tubulin polymerization inhibitors with potential anticancer and anti-inflammatory activities
Ahmed, Asmaa H.H., Mohamed, Mamdouh F.A., Allam, Rasha M., Nafady, Ayman, Mohamed, Shaaban K., Gouda, Ahmed E., Beshr, Eman A.M.
Published in Bioorganic chemistry (01.12.2022)
Published in Bioorganic chemistry (01.12.2022)
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Discovery of oxindole‐based FLT3 inhibitors as a promising therapeutic lead for acute myeloid leukemia carrying the oncogenic ITD mutation
Bender, Onur, Shoman, Mai E., Ali, Taha F. S., Dogan, Rumeysa, Celik, Ismail, Mollica, Adriano, Hamed, Mohammed I. A., Aly, Omar M., Alamri, Abdulwahab, Alanazi, Jowaher, Ahemad, Nafees, Gan, Siew Hua, Malik, Jonaid Ahmad, Anwar, Sirajudheen, Atalay, Arzu, Beshr, Eman A. M.
Published in Archiv der Pharmazie (Weinheim) (01.02.2023)
Published in Archiv der Pharmazie (Weinheim) (01.02.2023)
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Design, synthesis, cytotoxic activities, and molecular docking of chalcone hybrids bearing 8-hydroxyquinoline moiety with dual tubulin/EGFR kinase inhibition
Amin, Mohammed M., Abuo-Rahma, Gamal El-Din A., Shaykoon, Montaser Sh. A., Marzouk, Adel A., Abourehab, Mohammed A.S., Saraya, Roshdy E., Badr, Mohamed, Sayed, Ahmed M., Beshr, Eman A.M.
Published in Bioorganic chemistry (01.05.2023)
Published in Bioorganic chemistry (01.05.2023)
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1,2,4-Triazole/oxime hybrids as new strategy for nitric oxide donors: Synthesis, anti-inflammatory, ulceroginicity and antiproliferative activities
Abuo-Rahma, Gamal El-Din A.A., Abdel-Aziz, Mohamed, Beshr, Eman A.M., Ali, Taha F.S.
Published in European journal of medicinal chemistry (01.01.2014)
Published in European journal of medicinal chemistry (01.01.2014)
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New 1,3,4-oxadiazole/oxime hybrids: Design, synthesis, anti-inflammatory, COX inhibitory activities and ulcerogenic liability
Abd-Ellah, Heba S., Abdel-Aziz, Mohamed, Shoman, Mai E., Beshr, Eman A.M., Kaoud, TamerS, Ahmed, Al-Shaimaa F.F.
Published in Bioorganic chemistry (01.10.2017)
Published in Bioorganic chemistry (01.10.2017)
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Discovery of new cyanopyridine/chalcone hybrids as dual inhibitors of EGFR/BRAFV600E with promising antiproliferative properties
Abou‐Zied, Hesham A., Beshr, Eman A. M., Gomaa, Hesham A. M., Mostafa, Yaser A., Youssif, Bahaa G. M., Hayallah, Alaa M., Abdel‐Aziz, Mohamed
Published in Archiv der Pharmazie (Weinheim) (01.04.2023)
Published in Archiv der Pharmazie (Weinheim) (01.04.2023)
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Journal Article
Discovery of new cyanopyridine/chalcone hybrids as dual inhibitors of EGFR/BRAF V600E with promising antiproliferative properties
Abou-Zied, Hesham A, Beshr, Eman A M, Gomaa, Hesham A M, Mostafa, Yaser A, Youssif, Bahaa G M, Hayallah, Alaa M, Abdel-Aziz, Mohamed
Published in Archiv der Pharmazie (Weinheim) (01.04.2023)
Published in Archiv der Pharmazie (Weinheim) (01.04.2023)
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Novel 1,3,4-oxadiazole/oxime hybrids: Synthesis, docking studies and investigation of anti-inflammatory, ulcerogenic liability and analgesic activities
Abd-Ellah, Heba S., Abdel-Aziz, Mohamed, Shoman, Mai E., Beshr, Eman A.M., Kaoud, Tamer S., Ahmed, Al-Shaimaa F.F.
Published in Bioorganic chemistry (01.12.2016)
Published in Bioorganic chemistry (01.12.2016)
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HSP70 induction by bleomycin metal core analogs
Ali, Taha F.S., Taira, Naomi, Iwamaru, Kana, Koga, Ryoko, Kamo, Masahiro, Radwan, Mohamed O., Tateishi, Hiroshi, Kurosaki, Hiromasa, Abdel-Aziz, Mohamed, Abuo-Rahma, Gamal El-Din A.A., Beshr, Eman A.M., Otsuka, Masami, Fujita, Mikako
Published in Bioorganic & medicinal chemistry letters (01.04.2020)
Published in Bioorganic & medicinal chemistry letters (01.04.2020)
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Vanillin-Based Indolin-2-one Derivative Bearing a Pyridyl Moiety as a Promising Anti-Breast Cancer Agent via Anti-Estrogenic Activity
Bender, Onur, Celik, Ismail, Dogan, Rumeysa, Atalay, Arzu, Shoman, Mai E., Ali, Taha F. S., Beshr, Eman A. M., Mohamed, Mahmoud, Alaaeldin, Eman, Shawky, Ahmed M., Awad, Eman M., Ahmed, Al-Shaimaa F., Younes, Kareem M., Ansari, Mukhtar, Anwar, Sirajudheen
Published in ACS omega (21.02.2023)
Published in ACS omega (21.02.2023)
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