Asymmetric synthesis of L-azetidine-2-carboxylic acid and 3-substituted congeners—conformationally constrained analogs of phenylalanine, naphthylalanine, and leucine
Hanessian, Stephen, Bernstein, Naomy, Yang, Rui-Yang, Maguire, Robert
Published in Bioorganic & medicinal chemistry letters (17.05.1999)
Published in Bioorganic & medicinal chemistry letters (17.05.1999)
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Discovery of N-(2-Aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide (MGCD0103), an Orally Active Histone Deacetylase Inhibitor
Zhou, Nancy, Moradei, Oscar, Raeppel, Stephane, Leit, Silvana, Frechette, Sylvie, Gaudette, Frederic, Paquin, Isabelle, Bernstein, Naomy, Bouchain, Giliane, Vaisburg, Arkadii, Jin, Zhiyun, Gillespie, Jeff, Wang, James, Fournel, Marielle, Yan, Pu T, Trachy-Bourget, Marie-Claude, Kalita, Ann, Lu, Aihua, Rahil, Jubrail, MacLeod, A. Robert, Li, Zuomei, Besterman, Jeffrey M, Delorme, Daniel
Published in Journal of medicinal chemistry (24.07.2008)
Published in Journal of medicinal chemistry (24.07.2008)
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Discovery of a novel and potent series of thieno[3,2- b]pyridine-based inhibitors of c-Met and VEGFR2 tyrosine kinases
Claridge, Stephen, Raeppel, Franck, Granger, Marie-Claude, Bernstein, Naomy, Saavedra, Oscar, Zhan, Lijie, Llewellyn, David, Wahhab, Amal, Deziel, Robert, Rahil, Jubrail, Beaulieu, Normand, Nguyen, Hannah, Dupont, Isabelle, Barsalou, Annie, Beaulieu, Carole, Chute, Ian, Gravel, Serge, Robert, Marie-France, Lefebvre, Sylvain, Dubay, Marja, Pascal, Roussen, Gillespie, Jeff, Jin, Zhiyun, Wang, James, Besterman, Jeffrey M., MacLeod, A. Robert, Vaisburg, Arkadii
Published in Bioorganic & medicinal chemistry (01.05.2008)
Published in Bioorganic & medicinal chemistry (01.05.2008)
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Constrained ( l-)- S-adenosyl- l-homocysteine (SAH) analogues as DNA methyltransferase inhibitors
Isakovic, Ljubomir, Saavedra, Oscar M., Llewellyn, David B., Claridge, Stephen, Zhan, Lijie, Bernstein, Naomy, Vaisburg, Arkadii, Elowe, Nadine, Petschner, Andrea J., Rahil, Jubrail, Beaulieu, Norman, Gauthier, France, MacLeod, A. Robert, Delorme, Daniel, Besterman, Jeffrey M., Wahhab, Amal
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
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SAR around ( l)- S-adenosyl- l-homocysteine, an inhibitor of human DNA methyltransferase (DNMT) enzymes
Saavedra, Oscar M., Isakovic, Ljubomir, Llewellyn, David B., Zhan, Lijie, Bernstein, Naomy, Claridge, Stephen, Raeppel, Franck, Vaisburg, Arkadii, Elowe, Nadine, Petschner, Andrea J., Rahil, Jubrail, Beaulieu, Norman, MacLeod, A. Robert, Delorme, Daniel, Besterman, Jeffrey M., Wahhab, Amal
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
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Journal Article
Design and synthesis of 4-[( s-triazin-2-ylamino)methyl]- N-(2-aminophenyl)-benzamides and their analogues as a novel class of histone deacetylase inhibitors
Paquin, Isabelle, Raeppel, Stéphane, Leit, Silvana, Gaudette, Frédéric, Zhou, Nancy, Moradei, Oscar, Saavedra, Oscar, Bernstein, Naomy, Raeppel, Franck, Bouchain, Giliane, Fréchette, Sylvie, Woo, Soon H., Vaisburg, Arkadii, Fournel, Marielle, Kalita, Ann, Robert, Marie-France, Lu, Aihua, Trachy-Bourget, Marie-Claude, Yan, Pu Theresa, Liu, Jianhong, Rahil, Jubrail, MacLeod, A. Robert, Besterman, Jeffrey M., Li, Zuomei, Delorme, Daniel
Published in Bioorganic & medicinal chemistry (01.02.2008)
Published in Bioorganic & medicinal chemistry (01.02.2008)
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Journal Article
Structurally Simple Trichostatin A-Like Straight Chain Hydroxamates as Potent Histone Deacetylase Inhibitors
Woo, Soon Hyung, Frechette, Sylvie, Khalil, Elie Abou, Bouchain, Giliane, Vaisburg, Arkadii, Bernstein, Naomy, Moradei, Oscar, Leit, Silvana, Allan, Martin, Fournel, Marielle, Trachy-Bourget, Marie-Claude, Li, Zuomei, Besterman, Jeffrey M, Delorme, Daniel
Published in Journal of medicinal chemistry (20.06.2002)
Published in Journal of medicinal chemistry (20.06.2002)
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N-(2-Amino-phenyl)-4-(heteroarylmethyl)-benzamides as new histone deacetylase inhibitors
Vaisburg, Arkadii, Paquin, Isabelle, Bernstein, Naomy, Frechette, Sylvie, Gaudette, Frederic, Leit, Silvana, Moradei, Oscar, Raeppel, Stephane, Zhou, Nancy, Bouchain, Giliane, Woo, Soon Hyung, Jin, Zhiyun, Gillespie, Jeff, Wang, James, Fournel, Marielle, Yan, Pu Theresa, Trachy-Bourget, Marie-Claude, Robert, Marie-France, Lu, Aihua, Yuk, Jimmy, Rahil, Jubrail, MacLeod, A. Robert, Besterman, Jeffrey M., Li, Zuomei, Delorme, Daniel
Published in Bioorganic & medicinal chemistry letters (15.12.2007)
Published in Bioorganic & medicinal chemistry letters (15.12.2007)
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Journal Article
N super(3)-Arylmalonamides: A new series of thieno[3,2-b]pyridine based inhibitors of c-Met and VEGFR2 tyrosine kinases
Saavedra, Oscar, Claridge, Stephen, Zhan, Lijie, Raeppel, Franck, Granger, Marie-Claude, Raeppel, Stephane, Mannion, Michael, Gaudette, Frederic, Zhou, Nancy, Isakovic, Ljubomir, Bernstein, Naomy, Deziel, Robert, Nguyen, Hannah, Beaulieu, Normand, Beaulieu, Carole, Dupont, Isabelle, Wang, James, Macleod, ARobert, Besterman, Jeffrey M, Vaisburg, Arkadii
Published in Bioorganic & medicinal chemistry letters (15.12.2009)
Published in Bioorganic & medicinal chemistry letters (15.12.2009)
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Journal Article
N3-Arylmalonamides: A new series of thieno[3,2-b]pyridine based inhibitors of c-Met and VEGFR2 tyrosine kinases
Saavedra, Oscar, Claridge, Stephen, Zhan, Lijie, Raeppel, Franck, Granger, Marie-Claude, Raeppel, Stéphane, Mannion, Michael, Gaudette, Frédéric, Zhou, Nancy, Isakovic, Ljubomir, Bernstein, Naomy, Déziel, Robert, Nguyen, Hannah, Beaulieu, Normand, Beaulieu, Carole, Dupont, Isabelle, Wang, James, Macleod, A. Robert, Besterman, Jeffrey M., Vaisburg, Arkadii
Published in Bioorganic & medicinal chemistry letters (15.12.2009)
Published in Bioorganic & medicinal chemistry letters (15.12.2009)
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Journal Article
(2-Amino-phenyl)-amides of ω-substituted alkanoic acids as new histone deacetylase inhibitors
Vaisburg, Arkadii, Bernstein, Naomy, Frechette, Sylvie, Allan, Martin, Abou-Khalil, Elie, Leit, Silvana, Moradei, Oscar, Bouchain, Giliane, Wang, James, Woo, Soon Hyung, Fournel, Marielle, Yan, Pu T., Trachy-Bourget, Marie-Claude, Kalita, Ann, Beaulieu, Carole, Li, Zuomei, MacLeod, A.Robert, Besterman, Jeffrey M., Delorme, Daniel
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
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Year of Publication 25.05.2021
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inibidores de sinalização de receptor de vegf e de receptor de hgf e composição farmacêutica
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Year of Publication 11.12.2012
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Year of Publication 11.12.2012
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Inhibitors of VEGF receptor and HGF receptor signaling
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Year of Publication 11.12.2012
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Year of Publication 11.12.2012
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INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING
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Year of Publication 05.04.2012
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