Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets
Tham, Yow Keat, Bernardo, Bianca C., Ooi, Jenny Y. Y., Weeks, Kate L., McMullen, Julie R.
Published in Archives of Toxicology. Archiv für Toxikologie (01.09.2015)
Published in Archives of Toxicology. Archiv für Toxikologie (01.09.2015)
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Book Review
Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function
Bernardo, Bianca C, Gao, Xiao-Ming, Winbanks, Catherine E, Boey, Esther J. H, Tham, Yow Keat, Kiriazis, Helen, Gregorevic, Paul, Obad, Susanna, Kauppinen, Sakari, Du, Xiao-Jun, Lin, Ruby C. Y, McMullen, Julie R
Published in Proceedings of the National Academy of Sciences - PNAS (23.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (23.10.2012)
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Journal Article
The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass
Winbanks, Catherine E, Chen, Justin L, Qian, Hongwei, Liu, Yingying, Bernardo, Bianca C, Beyer, Claudia, Watt, Kevin I, Thomson, Rachel E, Connor, Timothy, Turner, Bradley J, McMullen, Julie R, Larsson, Lars, McGee, Sean L, Harrison, Craig A, Gregorevic, Paul
Published in The Journal of cell biology (28.10.2013)
Published in The Journal of cell biology (28.10.2013)
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Journal Article
Lipidomic Profiles of the Heart and Circulation in Response to Exercise versus Cardiac Pathology: A Resource of Potential Biomarkers and Drug Targets
Tham, Yow Keat, Bernardo, Bianca C., Huynh, Kevin, Ooi, Jenny Y.Y., Gao, Xiao Ming, Kiriazis, Helen, Giles, Corey, Meikle, Peter J., McMullen, Julie R.
Published in Cell reports (Cambridge) (04.09.2018)
Published in Cell reports (Cambridge) (04.09.2018)
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Journal Article
The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice
Sapra, Geeta, Tham, Yow Keat, Cemerlang, Nelly, Matsumoto, Aya, Kiriazis, Helen, Bernardo, Bianca C., Henstridge, Darren C., Ooi, Jenny Y. Y., Pretorius, Lynette, Boey, Esther J. H., Lim, Lydia, Sadoshima, Junichi, Meikle, Peter J., Mellet, Natalie A., Woodcock, Elizabeth A., Marasco, Silvana, Ueyama, Tomomi, Du, Xiao-Jun, Febbraio, Mark A., McMullen, Julie R.
Published in Nature communications (09.12.2014)
Published in Nature communications (09.12.2014)
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Journal Article
Cartilage Intermediate Layer Protein 2 (CILP-2) Is Expressed in Articular and Meniscal Cartilage and Down-regulated in Experimental Osteoarthritis
Bernardo, Bianca C., Belluoccio, Daniele, Rowley, Lynn, Little, Christopher B., Hansen, Uwe, Bateman, John F.
Published in The Journal of biological chemistry (28.10.2011)
Published in The Journal of biological chemistry (28.10.2011)
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Journal Article
Therapeutic silencing of miR-652 restores heart function and attenuates adverse remodeling in a setting of established pathological hypertrophy
Bernardo, Bianca C, Nguyen, Sally S, Winbanks, Catherine E, Gao, Xiao-Ming, Boey, Esther J H, Tham, Yow Keat, Kiriazis, Helen, Ooi, Jenny Y Y, Porrello, Enzo R, Igoor, Sindhu, Thomas, Colleen J, Gregorevic, Paul, Lin, Ruby C Y, Du, Xiao-Jun, McMullen, Julie R
Published in The FASEB journal (01.12.2014)
Published in The FASEB journal (01.12.2014)
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Journal Article
Generation of MicroRNA-34 Sponges and Tough Decoys for the Heart: Developments and Challenges
Bernardo, Bianca C, Gregorevic, Paul, Ritchie, Rebecca H, McMullen, Julie R
Published in Frontiers in pharmacology (21.09.2018)
Published in Frontiers in pharmacology (21.09.2018)
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Journal Article
Silencing of miR-34a attenuates cardiac dysfunction in a setting of moderate, but not severe, hypertrophic cardiomyopathy
Bernardo, Bianca C, Gao, Xiao-Ming, Tham, Yow Keat, Kiriazis, Helen, Winbanks, Catherine E, Ooi, Jenny Y Y, Boey, Esther J H, Obad, Susanna, Kauppinen, Sakari, Gregorevic, Paul, Du, Xiao-Jun, Lin, Ruby C Y, McMullen, Julie R
Published in PloS one (27.02.2014)
Published in PloS one (27.02.2014)
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Journal Article
Changes in the Chondrocyte and Extracellular Matrix Proteome during Post-natal Mouse Cartilage Development
Wilson, Richard, Norris, Emma L., Brachvogel, Bent, Angelucci, Constanza, Zivkovic, Snezana, Gordon, Lavinia, Bernardo, Bianca C., Stermann, Jacek, Sekiguchi, Kiyotoshi, Gorman, Jeffrey J., Bateman, John F.
Published in Molecular & cellular proteomics (01.01.2012)
Published in Molecular & cellular proteomics (01.01.2012)
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Journal Article
Gene delivery of medium chain acyl-coenzyme A dehydrogenase induces physiological cardiac hypertrophy and protects against pathological remodelling
Bernardo, Bianca C, Weeks, Kate L, Pongsukwechkul, Thawin, Gao, Xiaoming, Kiriazis, Helen, Cemerlang, Nelly, Boey, Esther J H, Tham, Yow Keat, Johnson, Chad J, Qian, Hongwei, Du, Xiao-Jun, Gregorevic, Paul, McMullen, Julie R
Published in Clinical science (1979) (14.02.2018)
Published in Clinical science (1979) (14.02.2018)
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Journal Article
The therapeutic potential of miRNAs regulated in settings of physiological cardiac hypertrophy
Ooi, Jenny Y Y, Bernardo, Bianca C, McMullen, Julie R
Published in Future medicinal chemistry (01.02.2014)
Published in Future medicinal chemistry (01.02.2014)
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Journal Article
Adeno-Associated Virus Gene Therapy: Translational Progress and Future Prospects in the Treatment of Heart Failure
Bass-Stringer, Sebastian, Bernardo, Bianca C., May, Clive N., Thomas, Colleen J., Weeks, Kate L., McMullen, Julie R.
Published in Heart, lung & circulation (01.11.2018)
Published in Heart, lung & circulation (01.11.2018)
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Journal Article
Long-Term Overexpression of Hsp70 Does Not Protect against Cardiac Dysfunction and Adverse Remodeling in a MURC Transgenic Mouse Model with Chronic Heart Failure and Atrial Fibrillation
Bernardo, Bianca C, Sapra, Geeta, Patterson, Natalie L, Cemerlang, Nelly, Kiriazis, Helen, Ueyama, Tomomi, Febbraio, Mark A, McMullen, Julie R
Published in PloS one (14.12.2015)
Published in PloS one (14.12.2015)
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Journal Article
β-Adrenergic Stimulation Induces Histone Deacetylase 5 (HDAC5) Nuclear Accumulation in Cardiomyocytes by B55α-PP2A-Mediated Dephosphorylation
Weeks, Kate L, Ranieri, Antonella, Karaś, Agnieszka, Bernardo, Bianca C, Ashcroft, Alexandra S, Molenaar, Chris, McMullen, Julie R, Avkiran, Metin
Published in Journal of the American Heart Association (01.04.2017)
Published in Journal of the American Heart Association (01.04.2017)
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