When NO. Is not Enough: Chemical Systems, Advances and Challenges in the Development of NO. and HNO Donors for Old and Current Medical Issues
Muniz Carvalho, Edinilton, Silva Sousa, Eduardo Henrique, Bernardes‐Génisson, Vania, Gonzaga de França Lopes, Luiz
Published in European journal of inorganic chemistry (15.11.2021)
Published in European journal of inorganic chemistry (15.11.2021)
Get full text
Journal Article
Phenyl dialkynylcarbinols, a Bioinspired Series of Synthetic Antitumor Acetylenic Lipids
Bossuat, Margaux, Rullière, Pauline, Preuilh, Nadège, Peixoto, Antonio, Joly, Etienne, Gomez, Jean-Guillaume, Bourkhis, Maroua, Rodriguez, Frédéric, Gonçalves, Fernanda, Fabing, Isabelle, Gaspard, Hafida, Bernardes-Génisson, Vania, Maraval, Valérie, Ballereau, Stéphanie, Chauvin, Remi, Britton, Sébastien, Génisson, Yves
Published in Journal of medicinal chemistry (26.10.2023)
Published in Journal of medicinal chemistry (26.10.2023)
Get full text
Journal Article
Further Insights into the Oxidative Pathway of Thiocarbonyl-Type Antitubercular Prodrugs: Ethionamide, Thioacetazone, and Isoxyl
de Freitas Paulo, Tércio, Duhayon, Carine, de França Lopes, Luiz Gonzaga, Silva Sousa, Eduardo Henrique, Chauvin, Remi, Bernardes-Génisson, Vania
Published in Chemical research in toxicology (16.08.2021)
Published in Chemical research in toxicology (16.08.2021)
Get full text
Journal Article
Pentacyanoferrate(II) complex of pyridine-4- and pyrazine-2-hydroxamic acid as source of HNO: investigation of anti-tubercular and vasodilation activities
Carvalho, Edinilton Muniz, de Freitas Paulo, Tercio, Saquet, Alix Sournia, Abbadi, Bruno Lopes, Macchi, Fernanda Souza, Bizarro, Cristiano Valim, de Morais Campos, Rafael, Ferreira, Talles Luann Abrantes, do Nascimento, Nilberto Robson Falcão, Lopes, Luiz Gonzaga França, Chauvin, Remi, Sousa, Eduardo Henrique Silva, Bernardes-Génisson, Vania
Published in Journal of biological inorganic chemistry (01.09.2020)
Published in Journal of biological inorganic chemistry (01.09.2020)
Get full text
Journal Article
THE FUNDAMENTAL IMPORTANCE OF BASIC SCIENCE: EXAMPLES OF HIGH-IMPACT DISCOVERIES FROM AN INTERNATIONAL CHEMISTRY NETWORK
Lopes, Luiz, Sadler, Peter, Bernardes-Génissond, Vânia, Moura, José, Chauvin, Remi, Bernhardt, Paul V., Sousa, Eduardo
Published in Química Nova (01.09.2020)
Published in Química Nova (01.09.2020)
Get full text
Journal Article
SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species
Demange, Pascal, Joly, Etienne, Marcoux, Julien, Zanon, Patrick R A, Listunov, Dymytrii, Rullière, Pauline, Barthes, Cécile, Noirot, Céline, Izquierdo, Jean-Baptiste, Rozié, Alexandrine, Pradines, Karen, Hee, Romain, de Brito, Maria Vieira, Marcellin, Marlène, Serre, Remy-Felix, Bouchez, Olivier, Burlet-Schiltz, Odile, Oliveira, Maria Conceição Ferreira, Ballereau, Stéphanie, Bernardes-Génisson, Vania, Maraval, Valérie, Calsou, Patrick, Hacker, Stephan M, Génisson, Yves, Chauvin, Remi, Britton, Sébastien
Published in eLife (10.05.2022)
Published in eLife (10.05.2022)
Get full text
Journal Article
Chemical synthesis, biological evaluation and structure–activity relationship analysis of azaisoindolinones, a novel class of direct enoyl-ACP reductase inhibitors as potential antimycobacterial agents
Deraeve, Céline, Dorobantu, Ioana Miruna, Rebbah, Farah, Le Quéméner, Frédéric, Constant, Patricia, Quémard, Annaïk, Bernardes-Génisson, Vania, Bernadou, Jean, Pratviel, Geneviève
Published in Bioorganic & medicinal chemistry (01.11.2011)
Published in Bioorganic & medicinal chemistry (01.11.2011)
Get full text
Journal Article
Chemical modification of clay nanocomposites for the improvement of the catalytic properties of Lipase A from Candida antarctica
Cavalcante, Antônio Luthierre Gama, Chaves, Anderson Valério, Fechine, Pierre Basílio Almeida, Holanda Alexandre, Jeferson Yves Nunes, Freire, Tiago Melo, Davi, Dalila Maria Barbosa, Neto, Francisco Simão, de Sousa, Isamayra Germano, da Silva Moreira, Katerine, de Oliveira, André Luiz Barros, de Mattos, Marcos Carlos, Oliveira, Maria Conceição Ferreira, de Brito, Maria Vieira, Ballereau, Stéphanie, Bernardes-Génisson, Vania, da Fonseca, Aluísio Marques, dos Santos, José C.S.
Published in Process biochemistry (1991) (01.09.2022)
Published in Process biochemistry (1991) (01.09.2022)
Get full text
Journal Article
Dendritic Pyridine-Imine Copper Complexes as Metallo-Drugs
Laurent, Régis, Maraval, Valérie, Bernardes-Génisson, Vania, Caminade, Anne-Marie
Published in Molecules (Basel, Switzerland) (01.04.2024)
Published in Molecules (Basel, Switzerland) (01.04.2024)
Get full text
Journal Article
Metalloporphyrin-Catalyzed Oxidation of Sunitinib and Pazopanib, Two Anticancer Tyrosine Kinase Inhibitors: Evidence for New Potentially Toxic Metabolites
Paludetto, Marie-Noëlle, Bijani, Christian, Puisset, Florent, Bernardes-Génisson, Vania, Arellano, Cécile, Robert, Anne
Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
Get full text
Journal Article
Involvement of Pazopanib and Sunitinib Aldehyde Reactive Metabolites in Toxicity and Drug–Drug Interactions in Vitro and in Patient Samples
Paludetto, Marie-Noëlle, Stigliani, Jean-Luc, Robert, Anne, Bernardes-Génisson, Vania, Chatelut, Etienne, Puisset, Florent, Arellano, Cécile
Published in Chemical research in toxicology (21.01.2020)
Published in Chemical research in toxicology (21.01.2020)
Get full text
Journal Article
A divergent mode of activation of a nitrosyl iron complex with unusual antiangiogenic activity
Carvalho, Edinilton Muniz, Ridnour, Lisa A., Júnior, Florêncio Sousa Gouveia, Cabral, Pedro Henrique Bezerra, do Nascimento, Nilberto Robson Falcão, Wink, David A., Franco, Douglas W., de Medeiros, Mayara Jane Campos, de Lima Pontes, Daniel, Longhinotti, Elisane, de Freitas Paulo, Tércio, Bernardes-Génisson, Vania, Chauvin, Remi, Sousa, Eduardo Henrique Silva, Lopes, Luiz Gonzaga de França
Published in Journal of inorganic biochemistry (01.09.2020)
Published in Journal of inorganic biochemistry (01.09.2020)
Get full text
Journal Article
Synthesis and mechanistic investigation of iron(II) complexes of isoniazid and derivatives as a redox-mediated activation strategy for anti-tuberculosis therapy
Laborde, Julie, Deraeve, Céline, de Mesquita Vieira, Francisca Gilmara, Sournia-Saquet, Alix, Rechignat, Lionel, Villela, Anne Drumond, Abbadi, Bruno Lopes, Macchi, Fernanda Souza, Pissinate, Kenia, Bizarro, Cristiano V., Machado, Pablo, Basso, Luiz Augusto, Pratviel, Geneviève, de França Lopes, Luiz Gonzaga, Sousa, Eduardo Henrique Silva, Bernardes-Génisson, Vania
Published in Journal of inorganic biochemistry (01.02.2018)
Published in Journal of inorganic biochemistry (01.02.2018)
Get full text
Journal Article
Development of isoniazid–NAD truncated adducts embedding a lipophilic fragment as potential bi-substrate InhA inhibitors and antimycobacterial agents
Delaine, Tamara, Bernardes-Génisson, Vania, Quémard, Annaïk, Constant, Patricia, Meunier, Bernard, Bernadou, Jean
Published in European journal of medicinal chemistry (01.10.2010)
Published in European journal of medicinal chemistry (01.10.2010)
Get full text
Journal Article
Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: toward in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis
Chollet, Aurélien, Stigliani, Jean-Luc, Pasca, Maria Rosalia, Mori, Giorgia, Lherbet, Christian, Constant, Patricia, Quémard, Annaïk, Bernadou, Jean, Pratviel, Geneviève, Bernardes-Génisson, Vania
Published in Chemical biology & drug design (01.11.2016)
Published in Chemical biology & drug design (01.11.2016)
Get full text
Journal Article
Reactivity of an o-Indoloquinone to 1-and 2-Azadienes
GENISSON, Vania BERNARDES, NEBOIS, Pascal
Published in Chemical & pharmaceutical bulletin (01.06.2000)
Published in Chemical & pharmaceutical bulletin (01.06.2000)
Get full text
Journal Article
Preliminary Investigations of the Effect of Lipophilic Analogues of the Active Metabolite of Isoniazid Toward Bacterial and Plasmodial Strains
Delaine, Tamara, Bernardes-Génisson, Vania, Quémard, Annaïk, Constant, Patricia, Cosledan, Frédéric, Meunier, Bernard, Bernadou, Jean
Published in Chemical biology & drug design (01.06.2012)
Published in Chemical biology & drug design (01.06.2012)
Get full text
Journal Article