Regulation of pancreas plasticity and malignant transformation by Akt signaling
Elghazi, Lynda, Weiss, Aaron J, Barker, Daniel J, Callaghan, John, Staloch, Lora, Sandgren, Eric P, Gannon, Maureen, Adsay, Volkan N, Bernal-Mizrachi, Ernesto
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2009)
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2009)
Get more information
Journal Article
Transient early food restriction leads to hypothalamic changes in the long‐lived crowded litter female mice
Sadagurski, Marianna, Landeryou, Taylor, Cady, Gillian, Bartke, Andrzej, Bernal‐Mizrachi, Ernesto, Miller, Richard A.
Published in Physiological reports (01.04.2015)
Published in Physiological reports (01.04.2015)
Get full text
Journal Article
Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors
Kogot-Levin, Aviram, Hinden, Liad, Riahi, Yael, Israeli, Tal, Tirosh, Boaz, Cerasi, Erol, Mizrachi, Ernesto Bernal, Tam, Joseph, Mosenzon, Ofri, Leibowitz, Gil
Published in Cell reports (Cambridge) (28.07.2020)
Published in Cell reports (Cambridge) (28.07.2020)
Get full text
Journal Article
Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing
Blandino-Rosano, Manuel, Barbaresso, Rebecca, Jimenez-Palomares, Margarita, Bozadjieva, Nadejda, Werneck-de-Castro, Joao Pedro, Hatanaka, Masayuki, Mirmira, Raghavendra G, Sonenberg, Nahum, Liu, Ming, Rüegg, Markus A, Hall, Michael N, Bernal-Mizrachi, Ernesto
Published in Nature communications (12.07.2017)
Published in Nature communications (12.07.2017)
Get full text
Journal Article
OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1
Mohan, Ramkumar, Jo, Seokwon, Lockridge, Amber, Ferrington, Deborah A, Murray, Kevin, Eschenlauer, Arthur, Bernal-Mizrachi, Ernesto, Fujitani, Yoshio, Alejandro, Emilyn U
Published in Diabetes (New York, N.Y.) (01.11.2021)
Published in Diabetes (New York, N.Y.) (01.11.2021)
Get full text
Journal Article
Unbiased Phosphoproteome Mining Reveals New Functional Sites of Metabolite-Derived PTMs Involved in MASLD Development
Moltó, Eduardo, Pintado, Cristina, Louzada, Ruy Andrade, Bernal-Mizrachi, Ernesto, Andrés, Antonio, Gallardo, Nilda, Bonzon-Kulichenko, Elena
Published in International journal of molecular sciences (01.11.2023)
Published in International journal of molecular sciences (01.11.2023)
Get full text
Journal Article
Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner
Carlson, Zach, Hafner, Hannah, Mulcahy, Molly, Bullock, Kaylie, Zhu, Allen, Bridges, Dave, Bernal-Mizrachi, Ernesto, Gregg, Brigid
Published in American journal of physiology: endocrinology and metabolism (01.05.2020)
Published in American journal of physiology: endocrinology and metabolism (01.05.2020)
Get full text
Journal Article
Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance
Skovsø, Søs, Panzhinskiy, Evgeniy, Kolic, Jelena, Cen, Haoning Howard, Dionne, Derek A, Dai, Xiao-Qing, Sharma, Rohit B, Elghazi, Lynda, Ellis, Cara E, Faulkner, Katharine, Marcil, Stephanie A M, Overby, Peter, Noursadeghi, Nilou, Hutchinson, Daria, Hu, Xiaoke, Li, Hong, Modi, Honey, Wildi, Jennifer S, Botezelli, J Diego, Noh, Hye Lim, Suk, Sujin, Gablaski, Brian, Bautista, Austin, Kim, Ryekjang, Cras-Méneur, Corentin, Flibotte, Stephane, Sinha, Sunita, Luciani, Dan S, Nislow, Corey, Rideout, Elizabeth J, Cytrynbaum, Eric N, Kim, Jason K, Bernal-Mizrachi, Ernesto, Alonso, Laura C, MacDonald, Patrick E, Johnson, James D
Published in Nature communications (08.02.2022)
Published in Nature communications (08.02.2022)
Get full text
Journal Article
Inhibition of Foxo1 Protects Pancreatic Islet β-Cells Against Fatty Acid and Endoplasmic Reticulum Stress–Induced Apoptosis
Martinez, Sara C, Tanabe, Katsuya, Cras-Méneur, Corentin, Abumrad, Nada A, Bernal-Mizrachi, Ernesto, Permutt, M Alan
Published in Diabetes (New York, N.Y.) (01.04.2008)
Published in Diabetes (New York, N.Y.) (01.04.2008)
Get full text
Journal Article
Disruption of Tsc2 in pancreatic β cells induces β cell mass expansion and improved glucose tolerance in a TORC1-dependent manner
Rachdi, Latif, Balcazar, Norman, Osorio-Duque, Fernando, Elghazi, Lynda, Weiss, Aaron, Gould, Aaron, Chang-Chen, Karen J, Gambello, Michael J, Bernal-Mizrachi, Ernesto
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2008)
Get full text
Journal Article
Inhibition of mTORC1 by ER stress impairs neonatal β-cell expansion and predisposes to diabetes in the Akita mouse
Riahi, Yael, Israeli, Tal, Yeroslaviz, Roni, Chimenez, Shoshana, Avrahami, Dana, Stolovich-Rain, Miri, Alter, Ido, Sebag, Marina, Polin, Nava, Bernal-Mizrachi, Ernesto, Dor, Yuval, Cerasi, Erol, Leibowitz, Gil
Published in eLife (09.11.2018)
Published in eLife (09.11.2018)
Get full text
Journal Article
Disruption of O-linked N-Acetylglucosamine Signaling Induces ER Stress and β Cell Failure
Alejandro, Emilyn U., Bozadjieva, Nadejda, Kumusoglu, Doga, Abdulhamid, Sarah, Levine, Hannah, Haataja, Leena, Vadrevu, Suryakiran, Satin, Leslie S., Arvan, Peter, Bernal-Mizrachi, Ernesto
Published in Cell reports (Cambridge) (22.12.2015)
Published in Cell reports (Cambridge) (22.12.2015)
Get full text
Journal Article
Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms
Hegedus, Balazs, Dasgupta, Biplab, Shin, Jung Eun, Emnett, Ryan J, Hart-Mahon, Elizabeth K, Elghazi, Lynda, Bernal-Mizrachi, Ernesto, Gutmann, David H
Published in Cell stem cell (11.10.2007)
Published in Cell stem cell (11.10.2007)
Get full text
Journal Article
Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells
Xu, Weiwei, Qadir, M.M. Fahd, Nasteska, Daniela, Mota de Sa, Paula, Gorvin, Caroline M., Blandino-Rosano, Manuel, Evans, Charles R., Ho, Thuong, Potapenko, Evgeniy, Veluthakal, Rajakrishnan, Ashford, Fiona B., Bitsi, Stavroula, Fan, Jia, Bhondeley, Manika, Song, Kejing, Sure, Venkata N., Sakamuri, Siva S.V.P., Schiffer, Lina, Beatty, Wandy, Wyatt, Rachael, Frigo, Daniel E., Liu, Xiaowen, Katakam, Prasad V., Arlt, Wiebke, Buck, Jochen, Levin, Lonny R., Hu, Tony, Kolls, Jay, Burant, Charles F., Tomas, Alejandra, Merrins, Matthew J., Thurmond, Debbie C., Bernal-Mizrachi, Ernesto, Hodson, David J., Mauvais-Jarvis, Franck
Published in Cell reports (Cambridge) (30.05.2023)
Published in Cell reports (Cambridge) (30.05.2023)
Get full text
Journal Article
Maternal High-Fat Diet During Pre-Conception and Gestation Predisposes Adult Female Offspring to Metabolic Dysfunction in Mice
Akhaphong, Brian, Gregg, Brigid, Kumusoglu, Doga, Jo, Seokwon, Singer, Kanakadurga, Scheys, Joshua, DelProposto, Jennifer, Lumeng, Carey, Bernal-Mizrachi, Ernesto, Alejandro, Emilyn U
Published in Frontiers in endocrinology (Lausanne) (17.01.2022)
Published in Frontiers in endocrinology (Lausanne) (17.01.2022)
Get full text
Journal Article
Raptor levels are critical for β-cell adaptation to a high-fat diet in male mice
Blandino-Rosano, Manuel, Louzada, Ruy Andrade, Werneck-De-Castro, Joao Pedro, Lubaczeuski, Camila, Almaça, Joana, Rüegg, Markus A., Hall, Michael N., Leibowitz, Gil, Bernal-Mizrachi, Ernesto
Published in Molecular metabolism (Germany) (01.09.2023)
Published in Molecular metabolism (Germany) (01.09.2023)
Get full text
Journal Article