New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells
Alburquerque-González, Begoña, Bernabé-García, Manuel, Montoro-García, Silvia, Bernabé-García, Ángel, Rodrigues, Priscila Campioni, Ruiz Sanz, Javier, López-Calderón, Fernando F., Luque, Irene, Nicolas, Francisco José, Cayuela, María Luisa, Salo, Tuula, Pérez-Sánchez, Horacio, Conesa-Zamora, Pablo
Published in Experimental & molecular medicine (01.02.2020)
Published in Experimental & molecular medicine (01.02.2020)
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Journal Article
Telomerase reverse transcriptase activates transcription of miR500A to inhibit Hedgehog signalling and promote cell invasiveness
Bernabé‐García, Manuel, Martínez‐Balsalobre, Elena, García‐Moreno, Diana, García‐Castillo, Jesús, Revilla‐Nuin, Beatriz, Blanco‐Alcaina, Elena, Mulero, Victoriano, Alcaraz‐Pérez, Francisca, Cayuela, María L.
Published in Molecular oncology (01.07.2021)
Published in Molecular oncology (01.07.2021)
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Journal Article
Monastrol suppresses invasion and metastasis in human colorectal cancer cells by targeting fascin independent of kinesin-Eg5 pathway
Alburquerque-González, Begoña, Montoro-García, Silvia, Bernabé-García, Ángel, Bernabé-García, Manuel, Campioni-Rodrigues, Priscila, Rodríguez-Martínez, Alejandro, Luque, Irene, Salo, Tuula, Pérez-Garrido, Alfonso, Pérez-Sánchez, Horacio, Cayuela, María Luisa, Luengo-Gil, Ginés, Luchinat, Enrico, Postigo-Corrales, Fatima, Staderini, Tommaso, Nicolás, Francisco José, Conesa-Zamora, Pablo
Published in Biomedicine & pharmacotherapy (01.06.2024)
Published in Biomedicine & pharmacotherapy (01.06.2024)
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Journal Article
The FDA-Approved Antiviral Raltegravir Inhibits Fascin1-Dependent Invasion of Colorectal Tumor Cells In Vitro and In Vivo
Alburquerque-González, Begoña, Bernabé-García, Ángel, Bernabé-García, Manuel, Ruiz-Sanz, Javier, López-Calderón, Fernando Feliciano, Gonnelli, Leonardo, Banci, Lucia, Peña-García, Jorge, Luque, Irene, Nicolás, Francisco José, Cayuela-Fuentes, María Luisa, Luchinat, Enrico, Pérez-Sánchez, Horacio, Montoro-García, Silvia, Conesa-Zamora, Pablo
Published in Cancers (18.02.2021)
Published in Cancers (18.02.2021)
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Journal Article
Premature aging in telomerase-deficient zebrafish
Anchelin, Monique, Alcaraz-Pérez, Francisca, Martínez, Carlos M, Bernabé-García, Manuel, Mulero, Victoriano, Cayuela, María L
Published in Disease models & mechanisms (01.09.2013)
Published in Disease models & mechanisms (01.09.2013)
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Journal Article
Novel anti-invasive properties of a Fascin1 inhibitor on colorectal cancer cells
Montoro-García, Silvia, Alburquerque-González, Begoña, Bernabé-García, Ángel, Bernabé-García, Manuel, Rodrigues, Priscila Campioni, den-Haan, Helena, Luque, Irene, Nicolás, Francisco José, Pérez-Sánchez, Horacio, Cayuela, María Luisa, Salo, Tuula, Conesa-Zamora, Pablo
Published in Journal of molecular medicine (Berlin, Germany) (01.03.2020)
Published in Journal of molecular medicine (Berlin, Germany) (01.03.2020)
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Journal Article
Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis
García-Castillo, Jesús, Alcaraz-Pérez, Francisca, Martínez-Balsalobre, Elena, García-Moreno, Diana, Rossmann, Marlies P., Fernández-Lajarín, Miriam, Bernabé-García, Manuel, Pérez-Oliva, Ana B., Rodríguez-Cortez, Virginia C., Bueno, Clara, Adatto, Isaac, Agarwal, Suneet, Menéndez, Pablo, Zon, Leonard I., Mulero, Victoriano, Cayuela, María L.
Published in Proceedings of the National Academy of Sciences - PNAS (10.08.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (10.08.2021)
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Journal Article
Corrigendum to “Monastrol suppresses invasion and metastasis in human colorectal cancer cells by targeting fascin independent of kinesin-Eg5 pathway” [Biomed. Pharmacother. 175 (2024) 116785]
Alburquerque-González, Begoña, Montoro-García, Silvia, Bernabé-García, Ángel, Bernabé-García, Manuel, Campioni-Rodrigues, Priscila, Rodríguez-Martínez, Alejandro, Luque, Irene, Salo, Tuula, Pérez-Garrido, Alfonso, Pérez-Sánchez, Horacio, Cayuela, María Luisa, Luengo-Gil, Ginés, Luchinat, Enrico, Postigo-Corrales, Fatima, Staderini, Tommaso, Nicolás, Francisco José, Conesa-Zamora, Pablo
Published in Biomedicine & pharmacotherapy (01.10.2024)
Published in Biomedicine & pharmacotherapy (01.10.2024)
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Journal Article
Corrigendum to "Monastrol suppresses invasion and metastasis in human colorectal cancer cells by targeting fascin independent of kinesin-Eg5 pathway" Biomed. Pharmacother. 175 (2024) 116785
Alburquerque-González, Begoña, Montoro-García, Silvia, Bernabé-García, Ángel, Bernabé-García, Manuel, Campioni-Rodrigues, Priscila, Rodríguez-Martínez, Alejandro, Luque, Irene, Salo, Tuula, Pérez-Garrido, Alfonso, Pérez-Sánchez, Horacio, Cayuela, María Luisa, Luengo-Gil, Ginés, Luchinat, Enrico, Postigo-Corrales, Fatima, Staderini, Tommaso, Nicolás, Francisco José, Conesa-Zamora, Pablo
Published in Biomedicine & pharmacotherapy (01.10.2024)
Published in Biomedicine & pharmacotherapy (01.10.2024)
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Journal Article
Inhibition of Lrrk2 reduces ethanol preference in a model of acute exposure in zebrafish
Paiva, Isadora Marques, de Carvalho, Luana Martins, Di Chiaccio, Isabela Martins, Lima Assis, Isadora de, Naranjo, Elena Sánchez, Bernabé, Manuel Garcia, Ferreira, Felipe Norberto Alves, Cayuela, Maria Luisa, Murgas, Luis David Solis, Brunialti Godard, Ana Lúcia
Published in Progress in neuro-psychopharmacology & biological psychiatry (08.06.2020)
Published in Progress in neuro-psychopharmacology & biological psychiatry (08.06.2020)
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Journal Article
TERT-mediated induction of MIR500A contributes to tumor invasiveness by targeting Hedgehog pathway
Bernabé-García, Manuel, Martínez-Balsalobre, Elena, García-Moreno, Diana, García-Castillo, Jesús, Revilla-Nuin, Beatriz, Blanco-Alcaina, Elena, Mulero, Victoriano, Alcaraz-Perez, Francisca, Cayuela, Maria L
Published in bioRxiv (19.02.2020)
Published in bioRxiv (19.02.2020)
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Paper
Imipramine for use as an inhibitor of fascin1 overexpression
NICOLÁS VILLAESCUSA, Francisco José, CAMPIONI RODRIGUES, Priscila, GARCÍA SOLANO, José, BERNABÉ GARCÍA, Angel, ALBURQUERQUE GONZALEZ, Begoña, MONTORO GARCÍA, Silvia, CONESA ZAMORA, Pablo, LUQUE FERNÁNDEZ, Irene, CAYUELA FUENTES, Maria Luisa, MARTÍNEZ HERRERÍAS, Jose Cristobal, SALO, Tuula, PEREZ SANCHEZ, Horacio, RUIZ SANZ, Javier, BERNABÉ GARCÍA, Manuel
Year of Publication 20.05.2021
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Year of Publication 20.05.2021
Patent
IMIPRAMINE FOR USE AS AN INHIBITOR OF FASCIN1 OVEREXPRESSION
NICOLÁS VILLAESCUSA, Francisco José, CAMPIONI RODRIGUES, Priscila, GARCÍA SOLANO, José, BERNABÉ GARCÍA, Angel, ALBURQUERQUE GONZALEZ, Begoña, MONTORO GARCÍA, Silvia, CONESA ZAMORA, Pablo, LUQUE FERNÁNDEZ, Irene, CAYUELA FUENTES, Maria Luisa, MARTÍNEZ HERRERÍAS, Jose Cristobal, SALO, Tuula, PEREZ SANCHEZ, Horacio, RUIZ SANZ, Javier, BERNABÉ GARCÍA, Manuel
Year of Publication 02.04.2020
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Year of Publication 02.04.2020
Patent
IMIPRAMINE FOR USE AS INHIBITOR OF FASCIN1 OVEREXPRESSION
GARCIA SOLANO, Jose, NICOLAS VILLAESCUSA, Francisco Jose, CAMPIONI RODRIGUES, Priscila, BERNABÉ GARCÍA, Angel, MARTINEZ HERRERIAS, Jose Cristobal, LUQUE FERNANDEZ, Irene, ALBURQUERQUE GONZALEZ, Begona, CONESA ZAMORA, Pablo, JAVIER, Ruiz Sanz, MONTORO GARCIA, Silvia, CAYUELA FUENTES, Maria Luisa, SALO, Tuula, PEREZ SANCHEZ, Horacio, BERNABÉ GARCÍA, Manuel
Year of Publication 01.04.2020
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Year of Publication 01.04.2020
Patent
Phosphorylation of NHERF1 S279 and S301 differentially regulates breast cancer cell phenotype and metastatic organotropism
Greco, Maria Raffaella, Bon, Emeline, Rubino, Rosa, Guerra, Lorenzo, Bernabe-Garcia, Manuel, Cannone, Stefania, Cayuela, Maria-Luisa, Ciaccia, Loredana, Marionneau-Lambot, Séverine, Oullier, Thibauld, Fromont, Gaëlle, Guibon, Roseline, Roger, Sébastien, Reshkin, Stephan Joel, Cardone, Rosa Angela
Published in Biochimica et biophysica acta. Molecular basis of disease (01.01.2019)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.01.2019)
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Journal Article
IMIPRAMINE FOR USE AS AN INHIBITOR OF FASCIN1 OVEREXPRESSION
LUQUEFERNANDEZ, Irene, NICOLÁS VILLAESCUSA, Francisco José, GARCÍA SOLANO, José, BERNABÉ GARCÍA, Angel, ALBURQUERQUE GONZALEZ, Begoña, CAMPIONI RODRIGUES, Prisclla, BERNABE GARCIA, Manuel, MARTINEZ HERRERiAS, Jose Cristobal, CONESA ZAMORA, Pablo, MONTORO GARCIA, Silvia, CAYUELA FUENTES, Maria Luisa, SALO, Tuula, PEREZ SANCHEZ, Horacio, RUIZ SANZ, Javier
Year of Publication 19.10.2023
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Year of Publication 19.10.2023
Patent
RALTEGRAVIR PARA USO COMO INHIBIDOR DE LA FASCINA1 EN CANCER
RUIZ SANZ, JAVIER, PEREZ SANCHEZ, HORACIO, NICOLAS VILLAESCUSA, FRANCISCO JOSE, CAYUELA FUENTES, MARIA LUISA, BERNABE GARCIA, MANUEL, PENA GARCIA, JORGE, CONESA ZAMORA, PABLO, LUQUE FERNANDEZ, IRENE, ALBURQUERQUE GONZALEZ, BEGONA, BERNABE GARCIA, ANGEL, MARTINEZ HERRERIAS, JOSE CRISTOBAL, GARCIA SOLANO, JOSE, MONTORO GARCIA, SILVIA
Year of Publication 15.06.2023
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Year of Publication 15.06.2023
Patent
IMIPRAMINE FOR USE AS AN INHIBITOR OF FASCIN1 OVEREXPRESSION
RUIZ SANZ, JAVIER, PEREZ SANCHEZ, HORACIO, NICOLAS VILLAESCUSA, FRANCISCO JOSE, CAYUELA FUENTES, MARIA LUISA, BERNABE GARCIA, MANUEL, CONESA ZAMORA, PABLO, SALO, TUULA, CAMPIONI RODRIGUES, PRISCILA, LUQUE FERNANDEZ, IRENE, ALBURQUERQUE GONZALEZ, BEGONA, BERNABE GARCIA, ANGEL, MARTINEZ HERRERIAS, JOSE CRISTOBAL, GARCIA SOLANO, JOSE, MONTORO GARCIA, SILVIA
Year of Publication 02.04.2020
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Year of Publication 02.04.2020
Patent
Raltegravir for use as a fascin1 inhibitor in cancer (Machine-translation by Google Translate, not legally binding)
RUIZ SANZ, JAVIER, PEREZ SANCHEZ, HORACIO, NICOLAS VILLAESCUSA, FRANCISCO JOSE, CAYUELA FUENTES, MARIA LUISA, BERNABE GARCIA, MANUEL, PENA GARCIA, JORGE, CONESA ZAMORA, PABLO, LUQUE FERNANDEZ, IRENE, ALBURQUERQUE GONZALEZ, BEGONA, BERNABE GARCIA, ANGEL, MARTINEZ HERRERIAS, JOSE CRISTOBAL, GARCIA SOLANO, JOSE, MONTORO GARCIA, SILVIA
Year of Publication 27.07.2022
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Year of Publication 27.07.2022
Patent