CRISPR/Cas9 gene editing for the creation of an MGAT1-deficient CHO cell line to control HIV-1 vaccine glycosylation
Byrne, Gabriel, O'Rourke, Sara M, Alexander, David L, Yu, Bin, Doran, Rachel C, Wright, Meredith, Chen, Qiushi, Azadi, Parastoo, Berman, Phillip W
Published in PLoS biology (29.08.2018)
Published in PLoS biology (29.08.2018)
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V1V2-specific complement activating serum IgG as a correlate of reduced HIV-1 infection risk in RV144
Perez, Lautaro G, Martinez, David R, deCamp, Allan C, Pinter, Abraham, Berman, Phillip W, Francis, Donald, Sinangil, Faruk, Lee, Carter, Greene, Kelli, Gao, Hongmei, Nitayaphan, Sorachai, Rerks-Ngarm, Supachai, Kaewkungwal, Jaranit, Pitisuttithum, Punnee, Tartaglia, James, O'Connell, Robert J, Robb, Merlin L, Michael, Nelson L, Kim, Jerome H, Gilbert, Peter, Montefiori, David C
Published in PloS one (05.07.2017)
Published in PloS one (05.07.2017)
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Gene editing in CHO cells to prevent proteolysis and enhance glycosylation: Production of HIV envelope proteins as vaccine immunogens
Li, Sophia W, Wright, Meredith, Healey, John F, Hutchinson, Jennie M, O'Rourke, Sara, Mesa, Kathryn A, Lollar, Pete, Berman, Phillip W
Published in PloS one (29.05.2020)
Published in PloS one (29.05.2020)
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Robotic selection for the rapid development of stable CHO cell lines for HIV vaccine production
O'Rourke, Sara M, Byrne, Gabriel, Tatsuno, Gwen, Wright, Meredith, Yu, Bin, Mesa, Kathryn A, Doran, Rachel C, Alexander, David, Berman, Phillip W
Published in PloS one (02.08.2018)
Published in PloS one (02.08.2018)
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Magnitude and Breadth of a Nonprotective Neutralizing Antibody Response in an Efficacy Trial of a Candidate HIV-1 gp120 Vaccine
Gilbert, Peter, Wang, Maggie, Wrin, Terri, Petropoulos, Chris, Gurwith, Marc, Sinangil, Faruk, D'Souza, Patricia, Rodriguez-Chavez, Isaac R., DeCamp, Allan, Giganti, Mike, Berman, Phillip W., Self, Steve G., Montefiori, David C.
Published in The Journal of infectious diseases (15.08.2010)
Published in The Journal of infectious diseases (15.08.2010)
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Glycan modifications to the gp120 immunogens used in the RV144 vaccine trial improve binding to broadly neutralizing antibodies
Doran, Rachel C, Tatsuno, Gwen P, O'Rourke, Sara M, Yu, Bin, Alexander, David L, Mesa, Kathryn A, Berman, Phillip W
Published in PloS one (24.04.2018)
Published in PloS one (24.04.2018)
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Correlation between Immunologic Responses to a Recombinant Glycoprotein 120 Vaccine and Incidence of HIV-1 Infection in a Phase 3 HIV-1 Preventive Vaccine Trial
Gilbert, Peter B., Peterson, Michael L., Follmann, Dean, Hudgens, Michael G., Francis, Donald P., Gurwith, Marc, Heyward, William L., Jobes, David V., Popovic, Vladimir, Self, Steven G., Sinangil, Faruk, Burke, Donald, Berman, Phillip W.
Published in The Journal of infectious diseases (01.03.2005)
Published in The Journal of infectious diseases (01.03.2005)
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Peptide Targeted by Human Antibodies Associated with HIV Vaccine-Associated Protection Assumes a Dynamic α-Helical Structure
Aiyegbo, Mohammed S, Shmelkov, Evgeny, Dominguez, Lorenzo, Goger, Michael, Battacharya, Shibani, deCamp, Allan C, Gilbert, Peter B, Berman, Phillip W, Cardozo, Timothy
Published in PloS one (01.01.2017)
Published in PloS one (01.01.2017)
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Ancestral sequences from an elite neutralizer proximal to the development of neutralization resistance as a potential source of HIV vaccine immunogens
Mesa, Kathryn A, Yu, Bin, Wrin, Terri, Petropoulos, Christos J, Pogson, Grant H, Alexander, David L, Perez, Gerardo, O'Rourke, Sara M, Sinangil, Faruk, Robinson, Joseph, Conant, Marcus A, Berman, Phillip W
Published in PloS one (10.04.2019)
Published in PloS one (10.04.2019)
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Unusual Cysteine Content in V1 Region of gp120 From an Elite Suppressor That Produces Broadly Neutralizing Antibodies
Hutchinson, Jennie M, Mesa, Kathryn A, Alexander, David L, Yu, Bin, O'Rourke, Sara M, Limoli, Kay L, Wrin, Terri, Deeks, Steven G, Berman, Phillip W
Published in Frontiers in immunology (15.05.2019)
Published in Frontiers in immunology (15.05.2019)
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Development of a Stable MGAT1 - CHO Cell Line to Produce Clade C gp120 With Improved Binding to Broadly Neutralizing Antibodies
Doran, Rachel C, Yu, Bin, Wright, Meredith, O'Rourke, Sara M, Yin, Lu, Richardson, Jennie M, Byrne, Gabriel, Mesa, Kathryn A, Berman, Phillip W
Published in Frontiers in immunology (05.10.2018)
Published in Frontiers in immunology (05.10.2018)
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Glycoform and net charge heterogeneity in gp120 immunogens used in HIV vaccine trials
Yu, Bin, Morales, Javier F, O'Rourke, Sara M, Tatsuno, Gwen P, Berman, Phillip W
Published in PloS one (22.08.2012)
Published in PloS one (22.08.2012)
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Glycans flanking the hypervariable connecting peptide between the A and B strands of the V1/V2 domain of HIV-1 gp120 confer resistance to antibodies that neutralize CRF01_AE viruses
O'Rourke, Sara M, Sutthent, Ruengpung, Phung, Pham, Mesa, Kathryn A, Frigon, Normand L, To, Briana, Horthongkham, Navin, Limoli, Kay, Wrin, Terri, Berman, Phillip W
Published in PloS one (20.03.2015)
Published in PloS one (20.03.2015)
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Mutation at a Single Position in the V2 Domain of the HIV-1 Envelope Protein Confers Neutralization Sensitivity to a Highly Neutralization-Resistant Virus
O'ROURKE, Sara M, SCHWEIGHARDT, Becky, PHUNG, Pham, FONSECA, Dora P. A. J, TERRY, Karianne, WRIN, Terri, SINANGIL, Faruk, BERMAN, Phillip W
Published in Journal of Virology (01.11.2010)
Published in Journal of Virology (01.11.2010)
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Phylodynamics of HIV-1 from a phase III AIDS vaccine trial in Bangkok, Thailand
Pérez-Losada, Marcos, Jobes, David V, Sinangil, Faruk, Crandall, Keith A, Arenas, Miguel, Posada, David, Berman, Phillip W
Published in PloS one (10.03.2011)
Published in PloS one (10.03.2011)
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Sequences in Glycoprotein gp41, the CD4 Binding Site, and the V2 Domain Regulate Sensitivity and Resistance of HIV-1 to Broadly Neutralizing Antibodies
O'ROURKE, Sara M, SCHWEIGHARDT, Becky, BERMAN, Phillip W, PHUNG, Pham, MESA, Kathryn A, VOLLRATH, Aaron L, TATSUNO, Gwen P, TO, Briana, SINANGIL, Faruk, LIMOLI, Kay, WRIN, Terri
Published in Journal of Virology (01.11.2012)
Published in Journal of Virology (01.11.2012)
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Journal Article
Novel Ring Structure in the gp41 Trimer of Human Immunodeficiency Virus Type 1 That Modulates Sensitivity and Resistance to Broadly Neutralizing Antibodies
O'ROURKE, Sara M, SCHWEIGHARDT, Becky, SCOTT, William G, WRIN, Terri, FONSECA, Dora P. A. J, SINANGIL, Faruk, BERMAN, Phillip W
Published in Journal of Virology (01.08.2009)
Published in Journal of Virology (01.08.2009)
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