Assessment of the safety, pharmacokinetics and pharmacodynamics of GSK3335065, an inhibitor of kynurenine monooxygenase, in a randomised placebo‐controlled first‐in‐human study in healthy volunteers
Fernando, Disala, Dimelow, Richard, Gorey, Ciara, Zhu, Xinyi, Muya, Catherine, Parker, Connie, Wright, Wayne, Soleman, Sara, Walsh, Sarah, Crause, Madelein, Vlasakakis, Georgios, Guiney, William, Robertson, Nicola, Bergeal, Marylise, Cui, Yi, Krug, Alexander W., Uings, Iain
Published in British journal of clinical pharmacology (01.02.2022)
Published in British journal of clinical pharmacology (01.02.2022)
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Development of a Series of Kynurenine 3‑Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis
Walker, Ann L, Ancellin, Nicolas, Beaufils, Benjamin, Bergeal, Marylise, Binnie, Margaret, Bouillot, Anne, Clapham, David, Denis, Alexis, Haslam, Carl P, Holmes, Duncan S, Hutchinson, Jonathan P, Liddle, John, McBride, Andrew, Mirguet, Olivier, Mowat, Christopher G, Rowland, Paul, Tiberghien, Nathalie, Trottet, Lionel, Uings, Iain, Webster, Scott P, Zheng, Xiaozhong, Mole, Damian J
Published in Journal of medicinal chemistry (27.04.2017)
Published in Journal of medicinal chemistry (27.04.2017)
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