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Boi, Roberto, Bergwall, Lovisa, Ebefors, Kerstin, Bergö, Martin O, Nyström, Jenny, Buvall, Lisa
Published in Journal of the American Society of Nephrology (01.04.2023)
Published in Journal of the American Society of Nephrology (01.04.2023)
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Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression
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Published in The Journal of clinical investigation (01.11.2013)
Published in The Journal of clinical investigation (01.11.2013)
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Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice
Jeong, Angela, Cheng, Shaowu, Zhong, Rui, Bennett, David A, Bergö, Martin O, Li, Ling
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Published in Acta neuropathologica communications (27.07.2021)
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The MTH1 inhibitor TH588 is a microtubule-modulating agent that eliminates cancer cells by activating the mitotic surveillance pathway
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Published in Scientific reports (11.10.2019)
Published in Scientific reports (11.10.2019)
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Rho-GTPase dependent leukocyte interaction generates pro-inflammatory thymic Tregs and causes arthritis
Malmhäll-Bah, Eric, Andersson, Karin M.E., Erlandsson, Malin C., Akula, Murali K., Brisslert, Mikael, Wiel, Clotilde, El Zowalaty, Ahmed E., Sayin, Volkan I., Bergö, Martin O., Bokarewa, Maria I.
Published in Journal of autoimmunity (01.06.2022)
Published in Journal of autoimmunity (01.06.2022)
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Genomic profiling of the transcription factor Zfp148 and its impact on the p53 pathway
Zou, Zhiyuan V., Gul, Nadia, Lindberg, Markus, Bokhari, Abdulmalik A., Eklund, Ella M., Garellick, Viktor, Patel, Angana A. H., Dzanan, Jozefina J., Titmuss, Ben O., Le Gal, Kristell, Johansson, Inger, Tivesten, Åsa, Forssell-Aronsson, Eva, Bergö, Martin O., Staffas, Anna, Larsson, Erik, Sayin, Volkan I., Lindahl, Per
Published in Scientific reports (25.08.2020)
Published in Scientific reports (25.08.2020)
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BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
Wiel, Clotilde, Le Gal, Kristell, Ibrahim, Mohamed X., Jahangir, Chowdhury Arif, Kashif, Muhammad, Yao, Haidong, Ziegler, Dorian V., Xu, Xiufeng, Ghosh, Tanushree, Mondal, Tanmoy, Kanduri, Chandrasekhar, Lindahl, Per, Sayin, Volkan I., Bergo, Martin O.
Published in Cell (11.07.2019)
Published in Cell (11.07.2019)
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Antioxidants accelerate lung cancer progression in mice
Sayin, Volkan I, Ibrahim, Mohamed X, Larsson, Erik, Nilsson, Jonas A, Lindahl, Per, Bergo, Martin O
Published in Science translational medicine (29.01.2014)
Published in Science translational medicine (29.01.2014)
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Antioxidants can increase melanoma metastasis in mice
Le Gal, Kristell, Ibrahim, Mohamed X, Wiel, Clotilde, Sayin, Volkan I, Akula, Murali K, Karlsson, Christin, Dalin, Martin G, Akyürek, Levent M, Lindahl, Per, Nilsson, Jonas, Bergo, Martin O
Published in Science translational medicine (07.10.2015)
Published in Science translational medicine (07.10.2015)
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Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions
Akula, Murali K., Ibrahim, Mohamed X., Ivarsson, Emil G., Khan, Omar M., Kumar, Israiel T., Erlandsson, Malin, Karlsson, Christin, Xu, Xiufeng, Brisslert, Mikael, Brakebusch, Cord, Wang, Donghai, Bokarewa, Maria, Sayin, Volkan I., Bergo, Martin O.
Published in Nature communications (04.09.2019)
Published in Nature communications (04.09.2019)
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Mevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress
Du, X., Zeng, H., Liu, S., Guy, C., Dhungana, Y., Neale, G., Bergö, Martin O., Chi, H.
Published in The Journal of experimental medicine (03.02.2020)
Published in The Journal of experimental medicine (03.02.2020)
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Lack of RAC1 in macrophages protects against atherosclerosis
Bandaru, Sashidar, Ala, Chandu, Ekstrand, Matias, Akula, Murali K, Pedrelli, Matteo, Liu, Xi, Bergström, Göran, Håversen, Liliana, Borén, Jan, Bergo, Martin O, Akyürek, Levent M, Lutgens, Esther, Bader, Michael
Published in PloS one (17.09.2020)
Published in PloS one (17.09.2020)
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SOX9 drives KRAS-induced lung adenocarcinoma progression and suppresses anti-tumor immunity
Zhong, Hua, Lu, Wen, Tang, Yong, Wiel, Clotilde, Wei, Yong, Cao, Jian, Riedlinger, Gregory, Papagiannakopoulos, Thales, Guo, Jessie Yanxiang, Bergo, Martin O., Kang, Yibin, Ganesan, Shridar, Sabaawy, Hatim E., Pine, Sharon R.
Published in Oncogene (30.06.2023)
Published in Oncogene (30.06.2023)
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Transient expression of an adenine base editor corrects the Hutchinson-Gilford progeria syndrome mutation and improves the skin phenotype in mice
Whisenant, Daniel, Lim, Kayeong, Revêchon, Gwladys, Yao, Haidong, Bergo, Martin O., Machtel, Piotr, Kim, Jin-Soo, Eriksson, Maria
Published in Nature communications (02.06.2022)
Published in Nature communications (02.06.2022)
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Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice
López-Posadas, Rocío, Fastancz, Petra, Martínez-Sánchez, Luz del Carmen, Panteleev-Ivlev, Julia, Thonn, Veronika, Kisseleva, Tatyana, Becker, Lukas S., Schulz-Kuhnt, Anja, Zundler, Sebastian, Wirtz, Stefan, Atreya, Raja, Carlé, Birgitta, Friedrich, Oliver, Schürmann, Sebastian, Waldner, Maximilian J., Neufert, Clemens, Brakebusch, Cord H., Bergö, Martin O., Neurath, Markus F., Atreya, Imke
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2019)
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Targeting Isoprenylcysteine Methylation Ameliorates Disease in a Mouse Model of Progeria
Ibrahim, Mohamed X., Sayin, Volkan I., Akula, Murali K., Liu, Meng, Fong, Loren G., Young, Stephen G., Bergo, Martin O.
Published in Science (American Association for the Advancement of Science) (14.06.2013)
Published in Science (American Association for the Advancement of Science) (14.06.2013)
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The long noncoding RNA ADIPINT regulates human adipocyte metabolism via pyruvate carboxylase
Kerr, Alastair G., Wang, Zuoneng, Wang, Na, Kwok, Kelvin H. M., Jalkanen, Jutta, Ludzki, Alison, Lecoutre, Simon, Langin, Dominique, Bergo, Martin O., Dahlman, Ingrid, Mim, Carsten, Arner, Peter, Gao, Hui
Published in Nature communications (26.05.2022)
Published in Nature communications (26.05.2022)
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Antioxidants stimulate BACH1-dependent tumor angiogenesis
Wang, Ting, Dong, Yongqiang, Huang, Zhiqiang, Zhang, Guoqing, Zhao, Ying, Yao, Haidong, Hu, Jianjiang, Tüksammel, Elin, Cai, Huan, Liang, Ning, Xu, Xiufeng, Yang, Xijie, Schmidt, Sarah, Qiao, Xi, Schlisio, Susanne, Strömblad, Staffan, Qian, Hong, Jiang, Changtao, Treuter, Eckardt, Bergo, Martin O.
Published in The Journal of clinical investigation (16.10.2023)
Published in The Journal of clinical investigation (16.10.2023)
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ROS-lowering doses of vitamins C and A accelerate malignant melanoma metastasis
Kashif, Muhammad, Yao, Haidong, Schmidt, Sarah, Chen, Xue, Truong, Michelle, Tüksammel, Elin, Liu, Yiran, Bergo, Martin O.
Published in Redox biology (01.04.2023)
Published in Redox biology (01.04.2023)
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